Professor Amirali Popat
Professor

Amirali Popat

Email: 
Phone: 
+61 7 334 61870

Background

Research Interests

  • Advanced Drug Delivery and Nanomedicine 1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Qualifications

  • Master of Pharmaceutical Science, Gujarat University
  • Bachelor of Pharmacy, Gujarat University

Availability

Professor Amirali Popat is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Chemical Sciences Inorganic chemistry Nanobiotechnology Nanomaterials Nanomedicine Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Pharmacy, Gujarat University
  • Masters (Research), Gujarat University

Research interests

  • Advanced Drug Delivery and Nanomedicine

    1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Search Professor Amirali Popat’s works on UQ eSpace

108 works between 2011 and 2025
All (108) Journal Article (97) Book Chapter (3) Conference Publication (3) Other Outputs (5)

81 - 100 of 108 works

2017

Journal Article

Bifunctional succinylated ε-polylysine-coated mesoporous silica nanoparticles for pH-responsive and intracellular drug delivery targeting the colon

Nguyen, Chau T. H., Webb, Richard I., Lambert, Lynette K., Strounina, Ekaterina, Lee, Edward C., Parat, Marie-Odile, McGuckin, Michael A., Popat, Amirali, Cabot, Peter J. and Ross, Benjamin P. (2017). Bifunctional succinylated ε-polylysine-coated mesoporous silica nanoparticles for pH-responsive and intracellular drug delivery targeting the colon. ACS Applied Materials and Interfaces, 9 (11), 9470-9483. doi: 10.1021/acsami.7b00411

Bifunctional succinylated ε-polylysine-coated mesoporous silica nanoparticles for pH-responsive and intracellular drug delivery targeting the colon

2017

Journal Article

Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles

Tyagi, Nisha, De, Ranjit, Begun, Jakob and Popat, Amirali (2017). Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles. International Journal of Pharmaceutics, 518 (1-2), 220-227. doi: 10.1016/j.ijpharm.2016.12.030

Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles

2017

Journal Article

Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate

Pujara, Naisarg, Jambhrunkar, Siddharth, Wong, Kuan Yau, McGuckin, Michael and Popat, Amirali (2017). Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate. Journal of Colloid and Interface Science, 488, 303-308. doi: 10.1016/j.jcis.2016.11.015

Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate

2016

Journal Article

GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses

Lee, Edward C., Davis-Poynter, Nicholas, Nguyen, Chau T. H., Peters, Amelia A., Monteith, Gregory R., Strounina, Ekaterina, Popat, Amirali and Ross, Benjamin P. (2016). GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses. Nanoscale, 8 (36), 16192-16196. doi: 10.1039/c6nr03878f

GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses

2016

Journal Article

Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol

Summerlin, Natalie, Qu, Zhi, Pujara, Naisarg, Sheng, Yong, Jambhrunkar, Siddharth, McGuckin, Michael and Popat, Amirali (2016). Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol. Colloids and Surfaces B: Biointerfaces, 144 (4), 1-7. doi: 10.1016/j.colsurfb.2016.03.076

Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol

2016

Journal Article

Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach

Soo, Ernest, Thakur, Sachin, Qu, Zhi, Jambhrunkar, Siddharth, Parekh, Harebdra S. and Popat, Amirali (2016). Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach. Journal of Colloid and Interface Science, 462, 368-374. doi: 10.1016/j.jcis.2015.10.022

Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach

2015

Journal Article

Resveratrol nanoformulations: challenges and opportunities

Summerlin, Natalie, Soo, Ernest, Thakur, Sachin, Qu, Zhi, Jambhrunkar, Siddharth and Popat, Amirali (2015). Resveratrol nanoformulations: challenges and opportunities. International Journal of Pharmaceutics, 479 (2), 282-290. doi: 10.1016/j.ijpharm.2015.01.003

Resveratrol nanoformulations: challenges and opportunities

2014

Journal Article

Floating tablets from mesoporous silica nanoparticles

Abbaraju, Prasanna Lakshmi, Meka, Anand kumar, Jambhrunkar, Siddharth, Zhang, Jun, Xu, Chun, Popat, Amirali and Yu, Chengzhong (2014). Floating tablets from mesoporous silica nanoparticles. Journal of Materials Chemistry B, 2 (47), 8298-8302. doi: 10.1039/c4tb01337a

Floating tablets from mesoporous silica nanoparticles

2014

Journal Article

Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein

Mody, Karishma T., Mahony, Donna, Zhang, Jun, Cavallaro, Antonino S., Zhang, Bing, Popat, Amirali, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2014). Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein. Biomaterials, 35 (37), 9972-9983. doi: 10.1016/j.biomaterials.2014.08.044

Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein

2014

Journal Article

Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency

Zhang, Jun, Raphael, Anthony P., Yang, Yannan, Popat, Amirali, Prow, Tarl W. and Yu, Chengzhong (2014). Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency. Journal of Materials Chemistry B, 2 (44), 7673-7678. doi: 10.1039/c4tb01332h

Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency

2014

Journal Article

Modulating in vitro release and solubility of griseofulvin using functionalized mesoporous silica nanoparticles

Jambhrunkar, Siddharth, Qu, Zhi, Popat, Amirali, Karmakar, Surajit, Xu, Chun and Yu, Chengzhong (2014). Modulating in vitro release and solubility of griseofulvin using functionalized mesoporous silica nanoparticles. Journal of Colloid and Interface Science, 434, 218-225. doi: 10.1016/j.jcis.2014.08.019

Modulating in vitro release and solubility of griseofulvin using functionalized mesoporous silica nanoparticles

2014

Journal Article

Effect of surface functionality of silica nanoparticles on cellular uptake and cytotoxicity

Jambhrunkar, Siddharth, Qu, Zhi, Popat, Amirali, Yang, Jie, Noonan, Owen, Acauan, Luiz, Ahmad Nor, Yusilawati, Yu, Chengzhong and Karmakar, Surajit (2014). Effect of surface functionality of silica nanoparticles on cellular uptake and cytotoxicity. Molecular Pharmaceutics, 11 (10), 3642-3655. doi: 10.1021/mp500385n

Effect of surface functionality of silica nanoparticles on cellular uptake and cytotoxicity

2014

Journal Article

Curcumin-cyclodextrin encapsulated chitosan nanoconjugates with enhanced solubility and cell cytotoxicity

Popat, Amirali, Karmakar, Surajit, Jambhrunkar, Siddharth, Xu, Chun and Yu, Chengzhong (2014). Curcumin-cyclodextrin encapsulated chitosan nanoconjugates with enhanced solubility and cell cytotoxicity. Colloids and Surfaces B: Biointerfaces, 117, 520-527. doi: 10.1016/j.colsurfb.2014.03.005

Curcumin-cyclodextrin encapsulated chitosan nanoconjugates with enhanced solubility and cell cytotoxicity

2014

Journal Article

Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery

Popat, Amirali, Jambhrunkar, Siddharth, Zhang, Jun, Yang, Jie, Zhang, Honwei, Meka, Anand and Yu, Chengzhong (2014). Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery. Chemical Communications, 50 (42), 5547-5550. doi: 10.1039/C4CC00620H

Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery

2014

Journal Article

Rod-like mesoporous silica nanoparticles with rough surfaces for enhanced cellular delivery

Xu, Chun, Niu, Yuting, Popat, Amirali, Jambhrunkar, Siddharth, Karmakar, Surajit and Yu, Chengzhong (2014). Rod-like mesoporous silica nanoparticles with rough surfaces for enhanced cellular delivery. Journal of Materials Chemistry B, 2 (3), 253-256. doi: 10.1039/c3tb21431a

Rod-like mesoporous silica nanoparticles with rough surfaces for enhanced cellular delivery

2014

Journal Article

Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

Jambhrunkar, Siddharth, Karmakar, Surajit, Popat, Amirali, Yu, Meihua and Yu, Chengzhong (2014). Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin. RSC Advances, 4 (2), 709-712. doi: 10.1039/c3ra44257h

Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

2014

Journal Article

Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy

Yang, Yannan, Karmakar, Surajit, Yu, Meihua, Popat, Amirali and Yu, Chengzhong (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, Article in press (3), 316-318. doi: 10.1246/cl.130930

Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy

2014

Journal Article

An overview of recent patents on nanosuspension

Modh, Nirav, Mehta, Dharmik, Parejiya, Punit, Popat, Amirali and Barot, Bhavesh (2014). An overview of recent patents on nanosuspension. Recent Patents on Drug Delivery and Formulation, 8 (2), 144-154. doi: 10.2174/1872211308666140422150819

An overview of recent patents on nanosuspension

2013

Journal Article

Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery

Mody, Karishma T., Popat, Amirali, Mahony, Donna, Cavallaro, Antonino S., Yu, Chengzhong and Mitter, Neena (2013). Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery. Nanoscale, 5 (12), 5167-5179. doi: 10.1039/c3nr00357d

Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery

2013

Journal Article

pH-Responsive Nutraceutical-Mesoporous Silica Nanoconjugates with Enhanced Colloidal Stability

Guillet-Nicolas, Rémy, Popat, Amirali, Bridot, Jean-Luc, Monteith, Gregory, Qiao, Shi Zhang and Kleitz, Freddy (2013). pH-Responsive Nutraceutical-Mesoporous Silica Nanoconjugates with Enhanced Colloidal Stability. Angewandte Chemie, 125 (8), 2374-2378. doi: 10.1002/ange.201208840

pH-Responsive Nutraceutical-Mesoporous Silica Nanoconjugates with Enhanced Colloidal Stability

Current funding

  • 2024 - 2025
    Targeting brain tumour using rationally designed nanomedicine
    Brain Foundation Research Grant
    Open grant
  • 2023 - 2028
    ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR)
    ARC Industrial Transformation Training Centres
    Open grant
  • 2020 - 2025
    Ovarian cancer early detection, monitoring and therapeutic intervention using extracellular vesicles
    NHMRC MRFF EPCDR - Ovarian Cancer Research
    Open grant

Past funding

  • 2024 - 2025
    Ultrasmall nanoparticles for overcoming biological barriers in the treatment of Glioblastoma
    Cure Cancer Early Career Research Grants
    Open grant
  • 2023 - 2024
    Overcome biological barriers in cancer for the treatment of glioblastoma using personalised nanomedicine
    TdC Pioneering Grant
    Open grant
  • 2023
    Compounding Personalised Medicines using 3D Printing
    UQ Knowledge Exchange & Translation Fund
    Open grant
  • 2021 - 2024
    Innovative delivery methods for the biologic soluble RAGE to prevent Type 1 Diabetes
    JDRF Pilot and Innovation Awards
    Open grant
  • 2019
    Enhanced osseointegration on growth factor releasing anodized 3D printed titanium dental implants with titania nanotubes
    Australian Dental Research Fund Inc
    Open grant
  • 2019 - 2021
    Parameters controlling naonparticle biodistribution upon oral administration under inflammatory conditions (Siloral)
    DAAD - German Academic Exchange Service
    Open grant
  • 2018 - 2020
    Encapsulation of plant extracts formulation using variety of protein based nanoparticles (former C03644-001)
    Integria Healthcare (Australia) Pty Ltd
    Open grant
  • 2018 - 2021
    Platform Nanotechnologies for Oral Delivery of Drugs, Therapeutic Protein and Peptide Delivery
    NHMRC Career Development Fellowship
    Open grant
  • 2017 - 2023
    Australian Centre for Cannabinoids and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community (NHMRC CRE administered by University of Newcastl
    University of Newcastle
    Open grant
  • 2016 - 2018
    HDAC3 as a novel orchestrator of lipid oxidation in the intestine and potential therapeutic target in obesity (NHMRC Project Grant administered by La Trobe University)
    La Trobe University
    Open grant
  • 2015
    Programmable nanoparticles for the treatment of Inflammatory Bowel Disease
    UQ Early Career Researcher
    Open grant
  • 2014 - 2017
    NHMRC Early Career Fellowship (Peter Doherty - Australian Biomedical Fellowship): Bioresponsive nanocarriers for controlled and targeted delivery to efficiently treat Inflamatory Bowel Disease (IBD)
    NHMRC Early Career Fellowships
    Open grant
  • 2014 - 2015
    Nanoencapsulation of bifenthrin for higher stability, efficacy, and controlled release.
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant

Availability

Professor Amirali Popat is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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