Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2026
Journal Article
Autism traits, ADHD symptoms, and stigma as predictors of social camouflaging in adults from the Australian ASD and ADHD study
Giblett, Matthew J., Lind, Penelope A. and Medland, Sarah E. (2026). Autism traits, ADHD symptoms, and stigma as predictors of social camouflaging in adults from the Australian ASD and ADHD study. Research in Neurodiversity, 2 100047, 1-11. doi: 10.1016/j.rin.2026.100047
2026
Journal Article
A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner
Boltz, Toni A., Chu, Benjamin B., DeFelice, Matthew, Liao, Calwing, Sealock, Julia M., Ye, Robert, Goldstein, Jacqueline I., Majara, Lerato, Fu, Jack M., Service, Susan K., Zhan, Lingyu, Medland, Sarah E., Chapman, Sinéad B., Rubinacci, Simone, Grimsby, Jonna L., Abebe, Tamrat, Alemayehu, Melkam, Ashaba, Fred K., Atkinson, Elizabeth G., Bigdeli, Tim B., Bradway, Amanda B., Brand, Harrison, Chibnik, Lori B., DeLuca, Samuel, Diaz-Zuluaga, Ana M., Fekadu, Abebaw, Gatzen, Michael, Gelaye, Bizu, Gichuru, Stella ... Martin, Alicia R. (2026). A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner. Nature Genetics. doi: 10.1038/s41588-026-02669-w
2026
Journal Article
Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorder
ter Kuile, Abigail R., Mitchell, Brittany L., Lee, Sang Hyuck, Morneau-Vaillancourt, Geneviève, Skelton, Megan, Coleman, Jonathan R. I., Davies, Helena L., Mundy, Jessica, Peel, Alicia J., Hübel, Christopher, Davies, Molly R., Fürtjes, Anna E., Ahmad, Zain, Lin, Yuhao, Adey, Brett N., McGregor, Thomas, Palmos, Alish, Zvrskovec, Johan, Hotopf, Matthew, Kalsi, Gursharan, Smith, Daniel J., Veale, David, Walters, James T. R., Armour, Chérie, Hirsch, Colette R., McIntosh, Andrew M., Wray, Naomi R., Medland, Sarah E., Byrne, Enda M. ... Eley, Thalia C. (2026). Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorder. Molecular Psychiatry, 1-14. doi: 10.1038/s41380-026-03677-2
2026
Journal Article
Can we improve the prediction of early onset mania and hypomania in the community?
Scott, Jan, Crouse, Jacob J., Medland, Sarah E., Mitchell, Brittany L., Gillespie, Nathan A., Martin, Nicholas G. and Hickie, Ian B. (2026). Can We Improve the Prediction of Early Onset Mania and Hypomania in the Community?. Bipolar Disorders, 28 (5) e70140, e70140-e70140. doi: 10.1111/bdi.70140
2026
Journal Article
Genetic and environmental influences on educational disparities in adult weight change: an individual-based pooled analysis of 11 twin cohorts
Obeso, Alvaro, Drouard, Gabin, Jelenkovic, Aline, Medda, Emanuela, Fagnani, Corrado, Toccaceli, Virgilia, Latvala, Antti, Aaltonen, Sari, Medland, Sarah E., Gordon, Scott D., Lee, Jooyeon, Lee, Soo Ji, Sung, Joohon, Pyun, Hyojin, Duncan, Glen E., Buchwald, Dedra, Ordoñana, Juan R., Sánchez-Romera, Juan F., Carrillo, Eduvigis, Franz, Carol E., Kremen, William S., Corley, Robin P., Huibregtse, Brooke M., Magnusson, Patrik KE, Karlsson, Ida K., Dahl Aslan, Anna K., Lyons, Michael J., Bartels, Meike, Ligthart, Lannie ... Silventoinen, Karri (2026). Genetic and environmental influences on educational disparities in adult weight change: an individual-based pooled analysis of 11 twin cohorts. International Journal of Obesity, 1-10. doi: 10.1038/s41366-026-02116-0
2026
Journal Article
Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry
Skelton, Megan, Mitchell, Brittany L., Assary, Elham, Li, Danyang, Morneau-Vaillancourt, Genevieve, Murphy, Alan E., ter Kuile, Abigail R., Wang, Rujia, Adams, Mark J., Byrne, Enda M., Corfield, Elizabeth C., Grimes, Poppy Z., Hannigan, Laurie J., Hu, Jihua, Kõiv, Kadri, Kwong, Alex S. F., Papiol, Sergi, Pettersen, Johanne H., Pistis, Giorgio, Castelao, Enrique, Strom, Nora I., van der Most, Peter J., Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Bacanu, Silviu-Alin, Cheesman, Rosa, Purves, Kirstin L., Gedik, Hüseyin, Faucon, Annika B., Singh, Kritika ... Eley, Thalia C. (2026). Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry. Nature Human Behaviour. doi: 10.1038/s41562-026-02476-7
2026
Journal Article
Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depression
Kiewa, Jacqueline, Lind, Penelope A., Hickie, Ian B., Medland, Sarah E., Mitchell, Brittany E., Middeldorp, Christel M., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2026). Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depression. Archives of Womens Mental Health, 29 (3) 71, 1-13. doi: 10.1007/s00737-026-01708-z
2026
Journal Article
Development of a perinatal trauma screening tool: Detecting the silent struggle of perinatal post-traumatic stress disorder
Mackle, Tracey, Colodro-Conde, Lucia, De Dassel, Therese, Clarkson, Tessa R., Grasby, Katrina L., Braun, Anastasia N., Burke, Kylie and Medland, Sarah E. (2026). Development of a perinatal trauma screening tool: Detecting the silent struggle of perinatal post-traumatic stress disorder. Australian and New Zealand Journal of Psychiatry. doi: 10.1177/00048674261434407
2026
Journal Article
A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma
Jayasinghe, G. J. M. Shanika R., Zhu, Gu, Pandeya, Nirmala, Olsen, Catherine M., Martin, Nicholas G., Lind, Penelope A., Medland, Sarah E., Gordon, Scott D., Diaz-Torres, Santiago, Lingham, Gareth, Lee, Samantha S. Y., Nijsten, Tamar, Kayser, Manfred, Pardo, Luba M., Montgomery, Grant W., Hayward, Nicholas K., Palmer, Jane M., Hunter, David J., Han, Jiali, Hewitt, Alex W., Falchi, Mario, Bishop, D. Timothy, Brown, Kevin M., Bataille, Veronique, Mackey, David A., Iles, Mark M., Whiteman, David C., Duffy, David L., MacGregor, Stuart and Law, Matthew H. (2026). A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma. Nature Communications, 17 (1) 3772, 1-11. doi: 10.1038/s41467-026-70368-5
2026
Journal Article
Deciphering the causal influence of BMI and related metabolic, inflammatory, and cardiovascular factors on brain structure: a Mendelian Randomization Study
Painter, Jodie N., Refisch, Alexander, Rau, Moritz, Walter, Martin, Mackey, Scott, Laurent, Jennifer, Thompson, Paul M., Grasby, Katrina L., Hajek, Tomas, Medland, Sarah E. and Opel, Nils (2026). Deciphering the causal influence of BMI and related metabolic, inflammatory, and cardiovascular factors on brain structure: a Mendelian Randomization Study. Molecular Psychiatry, 31 (7), 1-8. doi: 10.1038/s41380-026-03501-x
2026
Journal Article
Genetic and phenotypic associations With sustained antidepressant use in major depressive disorder
Walker, Alicia, Mitchell, Brittany L., Lin, Tian, Crouse, Jacob J., Albinana, Clara, Yap, Chloe X., Lynall, Mary Ellen, Lind, Penelope A., Cipriani, Andrea, Byrne, Enda M., Medland, Sarah E., Martin, Nicholas G., Taquet, Maxime, Hickie, Ian B. and Wray, Naomi R. (2026). Genetic and phenotypic associations With sustained antidepressant use in major depressive disorder. Jama Psychiatry, 83 (3), 247-258. doi: 10.1001/jamapsychiatry.2025.4372
2026
Journal Article
Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies
Shen, Xueyi, Toenders, Yara J., Han, Laura K. M., Weihs, Antoine, Alexander, Nina, Andlauer, Till F. M., Brosch, Katharina, Forstner, Andreas J., Grotegerd, Dominik, Hahn, Tim, Hermesdorf, Marco, Hosten, Norbert, Jamalabadi, Hamidreza, Meinert, Susanne, Milaneschi, Yuri, Sämann, Philipp G., Stein, Frederike, Stolicyn, Aleks, Teutenberg, Lea, Thng, Gladi, Adams, Mark J., Thomas-Odenthal, Florian, Usemann, Paula, Völker, Uwe, Wittfeld, Katharina, Herrera-Rivero, Marisol, Jiang, Yunxuan, Tian, Chao, on behalf of the 23andMe Research Team ... de Zubicaray, Greig (2025). Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies. Molecular Psychiatry, 31 (2), 611-621. doi: 10.1038/s41380-025-03136-4
2026
Journal Article
Unravelling sex differences in the genetic architecture of anxiety
Hu, Jihua, Lupton, Michelle K., Byrne, Enda M., Martin, Nicholas G., Whiteman, David C., Olsen, Catherine M., Thomas, Jodi T., Medland, Sarah E., Grasby, Katrina L. and Mitchell, Brittany L. (2026). Unravelling sex differences in the genetic architecture of anxiety. Psychological Medicine, 56 e191, e191-56. doi: 10.1017/s0033291726104760
2026
Journal Article
Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapies
Koch, Elise, Puusepp, Tuuli, Einarsson, Guðmundur, Mitchell, Brittany L., Harder, Arvid, Lin, Yuhao, García-Marín, Luis M., Krebs, Kristi, Shadrin, Alexey A., Xiong, Ying, Estonian Biobank Research Team, Metspalu, Andres, Esko, Tõnu, Mägi, Reedik, Nelis, Mari, Hudjashov, Georgi, Frei, Oleksandr, Lu, Yi, Hägg, Sara, Rentería, Miguel E., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G., Hübel, Christopher, Breen, Gerome, Thorgeirsson, Thorgeir, Stefánsson, Hreinn, Stefánsson, Kári, Lehto, Kelli ... O’Connell, Kevin S. (2026). Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapies. Molecular Psychiatry, 31 (4), 2005-2013. doi: 10.1038/s41380-025-03357-7
2026
Journal Article
Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohorts
Obeso, Alvaro, Drouard, Gabin, Jelenkovic, Aline, Ordoñana, Juan R., Sánchez-Romera, Juan F., Colodro-Conde, Lucía, Ollikainen, Miina, Aaltonen, Sari, Corley, Robin P., Huibregtse, Brooke M., Medda, Emanuela, Fagnani, Corrado, Toccaceli, Virgilia, Gatz, Margaret, Butler, David A., Bartels, Meike, Ligthart, Lannie, de Geus, Eco JC, Christensen, Kaare, Skytthe, Axel, Kyvik, Kirsten O., Medland, Sarah E., Gordon, Scott D., Rasmussen, Finn E., Tynelius, Per, Franz, Carol E., Kremen, William S., Lyons, Michael J., Spector, Timothy ... Silventoinen, Karri (2026). Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohorts. International Journal of Obesity, 50 (4), 768-776. doi: 10.1038/s41366-025-01998-w
2026
Journal Article
Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profile
Shin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, Mckenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Merikangas, Kathleen R., Wray, Naomi R., Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2026). Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profile. Biological Psychiatry. doi: 10.1016/j.biopsych.2026.01.003
2025
Journal Article
Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk
Curtis, Madeleine, Colodro‐Conde, Lucia, Medland, Sarah E., Gordon, Scott, Martin, Nicholas G., Wade, Tracey D. and Cohen‐Woods, Sarah (2025). Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk. Journal of Child Psychology and Psychiatry, 66 (12), 1795-1806. doi: 10.1111/jcpp.70012
2025
Journal Article
An exploration of the genetic architecture of pregnancy-related linea nigra and its relationship with pigmentation phenotypes
Bivol, Svetlana, Seviiri, Mathias, Colodro-Conde, Lucia, Mitchell, Brittany L., Olsen, Catherine M., Whiteman, David C., Law, Matthew H., Lind, Penelope A., Painter, Jodie N. and Medland, Sarah E. (2025). An exploration of the genetic architecture of pregnancy-related linea nigra and its relationship with pigmentation phenotypes. Twin Research and Human Genetics, 28 (5), 409-415. doi: 10.1017/thg.2025.10026
2025
Journal Article
The genetic architecture of the human corpus callosum and its subregions
Bhatt, Ravi R., Gadewar, Shruti P., Shetty, Ankush, Ba Gari, Iyad, Haddad, Elizabeth, Javid, Shayan, Ramesh, Abhinaav, Nourollahimoghadam, Elnaz, Zhu, Alyssa H., de Leeuw, Christiaan, Thompson, Paul M., Medland, Sarah E. and Jahanshad, Neda (2025). The genetic architecture of the human corpus callosum and its subregions. Nature Communications, 16 (1) 9708, 1-20. doi: 10.1038/s41467-025-64791-3
2025
Conference Publication
Quantifying the impact of genetic variation on healthcare cost across 1.4 million individuals from 11 studies and 7 countries: the GenCost consortium (Award Candidate)
May-Wilson, Sebastian Marcus, Nakanishi, Tomoko, Lee, Jiwoo, Dixon, Padraig, Davies, Neil, Ganna, Andrea, Vork, Andres, Milani, Lili, Abner, Erik, van Heel, David, Kanoni, Stavroula, van der Laan, Camiel M., Boomsma, Dorret, Brunak, Soren, Banasik, Karina, Louloudis, Ioannis, McCartney, Daniel, Marioni, Riccardo, Richmond, Anne, Yang, Zhiyu, Fahr, Patrick, Lind, Penelope, Medland, Sarah, Zguro, Kristina, Mbarek, Hamdi, Saad, Chadi, Torkki, Paulus M., Speed, Doug and German, Jakob (2025). Quantifying the impact of genetic variation on healthcare cost across 1.4 million individuals from 11 studies and 7 countries: the GenCost consortium (Award Candidate). 58th Conference of the European-Society-of-Human-Genetics (ESHG), Milan Italy, May 24-27, 2025. LONDON: SPRINGERNATURE.
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Doctor Philosophy
Support, Stigma, and Attitudes towards Autism andADHD in Adults and Parents from the Australian ASD and ADHD Study
Principal Advisor
-
Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Principal Advisor
Other advisors: Professor Dan Siskind
-
Master Philosophy
Novel efficient statistical methods for biobank-scale prediction from brain imaging
Principal Advisor
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Associate Advisor
Other advisors: Honorary Professor Nick Martin
Completed supervision
-
2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
-
2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
-
2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Honorary Professor Nick Martin
-
2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
-
2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Honorary Professor Nick Martin, Dr Lucia Colodro-Conde
-
-
2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Honorary Professor Nick Martin
-
2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Honorary Professor Nick Martin
-
2011
Doctor Philosophy
Genetic influences on quality of life throughout the life span: Genetic and environmental influences on the variation in and covariation among traits related to quality of life throughout life time and in the aged.
Associate Advisor
Other advisors: Honorary Professor Nick Martin
Media
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