Honorary Professor

Sarah Medland

Email: 

Background

Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.

Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.

ORCID: 0000-0003-1382-380X

ResearcherID: C-7630-2013

Scopus Author ID: 34571085600

Email: sarah.medland@qimrberghofer.edu.au

Qualifications

2006 PhD (Psychology), University of Queensland

Dean's Award for Outstanding Research Higher Degree Thesis

2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)

Availability

Honorary Professor Sarah Medland is:
Available for supervision

Fields of research

Applied economics Psychology

Search Professor Sarah Medland’s works on UQ eSpace

525 works between 2001 and 2025
All (525) Journal Article (443) Other Outputs (1) Conference Publication (76) Book Chapter (5)

1 - 20 of 525 works

2025

Conference Publication

Brain region-specific genetic architecture of suicidal ideation and attempt: insights from stratified LDSC, SMR, and functional enrichment analyses

Ceja, Zuriel, Edwards, Alexis, Martin, Nick, Medland, Sarah E. and Rentería, Miguel E. (2025). Brain region-specific genetic architecture of suicidal ideation and attempt: insights from stratified LDSC, SMR, and functional enrichment analyses. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.283

Brain region-specific genetic architecture of suicidal ideation and attempt: insights from stratified LDSC, SMR, and functional enrichment analyses

2025

Conference Publication

Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scripts

Walker, Alicia, Mitchell, Brittany, Lin, Tian, Crouse, Jacob, Martin, Nick, Taquet, Maxime, Medland, Sarah E., Hickie, Ian and Wray, Naomi (2025). Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scripts. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.504

Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scripts

2025

Conference Publication

Polygenic scores for eating disorders as a putative predictor for suicide behaviour

Aguilar-Roldan, Aura, Ceja, Zuriel, Medland, Sarah E., Martin, Nick and Rentería, Miguel E. (2025). Polygenic scores for eating disorders as a putative predictor for suicide behaviour. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.564

Polygenic scores for eating disorders as a putative predictor for suicide behaviour

2025

Journal Article

Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

Silva, Ana I., Sønderby, Ida E., Kirov, George, Abdellaoui, Abdel, Agartz, Ingrid, Ames, David, Armstrong, Nicola J., Artiges, Eric, Banaschewski, Tobias, Bassett, Anne S., Bearden, Carrie E., Blangero, John, Boen, Rune, Boomsma, Dorret I., Bülow, Robin, Butcher, Nancy J., Calhoun, Vince, Campbell, Linda E., Chow, Eva W.C., Ciufolini, Simone, Craig, Michael C., Crespo-Farroco, Benedicto, Cunningham, Adam C., Dalvie, Shareefa, Daly, Eileen, Dazzan, Paola, de Geus, Eco J.C., de Zubicaray, Greig I., Doherty, Joanne L. ... for the ENIGMA-CNV working group (2025). Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 10 (10), 1093-1106. doi: 10.1016/j.bpsc.2025.05.010

Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

2025

Conference Publication

Seeing the forest but not the trees: a lack of stability in polygenic risk scores

Ferreira, Andreza, Lind, Penelope A., Parker, Richard, Cross, Simone, Moody, Hayley, Medland, Richard and Medland, Sarah E. (2025). Seeing the forest but not the trees: a lack of stability in polygenic risk scores. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.228

Seeing the forest but not the trees: a lack of stability in polygenic risk scores

2025

Conference Publication

Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank

Hu, Jihua, Lupton, Michelle, Byrne, Enda M., Martin, Nicholas G., Whiteman, David, Olsen, Catherine, Thomas, Jodi, Medland, Sarah E., Grasby, Katrina and Mitchell, Brittany (2025). Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.288

Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank

2025

Journal Article

Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

van der Laan, Camiel M., Ip, Hill F., Schipper, Marijn, Hottenga, Jouke-Jan, St Pourcain, Beate, Zayats, Tetyana, Pool, René, Krapohl, Eva M. L., Brikell, Isabell, Soler Artigas, María, Cabana-Domínguez, Judit, Llonga, Natalia, Nolte, Ilja M., Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Gordon, Scott, Aliev, Fazil, Burt, S. Alexandra, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S. ... Boomsma, Dorret I. (2025). Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. Nature Genetics, 57 (10), 1-1. doi: 10.1038/s41588-025-02383-z

Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

2025

Conference Publication

Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression

Crouse, Jacob, Park, Shin Ho, Mitchell, Brittany, Byrne, Enda, Medland, Sarah, Lin, Tian, Scott, Jan, de Haan, Zsofi, Tonini, Emiliana, Iorfino, Frank, Wray, Naomi, Martin, Nicholas and Hickie, Ian (2025). Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression. HOBOKEN: WILEY.

Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression

2025

Conference Publication

Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression

Shin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, McKenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Wray, Naomi, Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2025). Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression. HOBOKEN: WILEY.

Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression

2025

Conference Publication

Circadian Depression Subtype in Adolescents: Validation Using the Brisbane Longitudinal Twin Study

Shin, Mirim, Crouse, Jacob J., Mitchell, Brittany L., Park, Shin Ho, Tonini, Emiliana, Carpenter, Joanne S., Mcaloney, Kerrie, Byrne, Enda, Medland, Sarah, Martin, Nicholas and Hickie, Ian B. (2025). Circadian Depression Subtype in Adolescents: Validation Using the Brisbane Longitudinal Twin Study. HOBOKEN: WILEY.

Circadian Depression Subtype in Adolescents: Validation Using the Brisbane Longitudinal Twin Study

2025

Journal Article

A systematic analysis of contemporary whole exome sequencing capture kits to optimise high-coverage capture of CCDS regions

Lopez, Fernando Vazquez, Ashton, James J., Cheng, Guo and Ennis, Sarah (2025). A systematic analysis of contemporary whole exome sequencing capture kits to optimise high-coverage capture of CCDS regions. Nar Genomics and Bioinformatics, 7 (3) lqaf115. doi: 10.1093/nargab/lqaf115

A systematic analysis of contemporary whole exome sequencing capture kits to optimise high-coverage capture of CCDS regions

2025

Conference Publication

Clinical and Genetic Correlates of Circadian Depression in the Australian Genetics of Depression Study

Tonini, Emiliana, Crouse, Jacob J., Byrne, Enda, Mitchell, Brittany L., Shin, Mirim, Carpenter, Joanne S., Medland, Sarah, Scott, Jan, Martin, Nicholas G. and Hickie, Ian B. (2025). Clinical and Genetic Correlates of Circadian Depression in the Australian Genetics of Depression Study. HOBOKEN: WILEY.

Clinical and Genetic Correlates of Circadian Depression in the Australian Genetics of Depression Study

2025

Journal Article

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits

Johnson, Emma C., Lai, Dongbing, Balbona, Jared V., Miller, Alex P., Hatoum, Alexander S., Deak, Joseph D., Jennings, Mariela, Baranger, David A. A., Galimberti, Marco, Sanichwankul, Kittipong, Thorgeirsson, Thorgeir, Colbert, Sarah M. C., Adhikari, Keyrun, Docherty, Anna R., Degenhardt, Louisa, Edwards, Tobias, Fox, Louis, Giannelis, Alexandros, Jeffries, Paul W., Korhonen, Tellervo, Morrison, Claire L., Nunez, Yaira Z., Palviainen, Teemu, Su, Mei-Hsin, Romero Villela, Pamela N., Wetherill, Leah, Willoughby, Emily A., Zellers, Stephanie M., Bierut, Laura J. ... Agrawal, Arpana (2025). Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychological Medicine, 55 e234. doi: 10.1017/S0033291725100883

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits

2025

Journal Article

Exploring the Relationship between Polygenic Scores, Community-Shared Socioeconomic Indicators and Major Depressive Disorder Outcome

Sepulveda, Dante T., Thorp, Jackson G., Lind, Penelope A., Martin, Nicholas G., Medland, Sarah E. and Mitchell, Brittany L. (2025). Exploring the Relationship between Polygenic Scores, Community-Shared Socioeconomic Indicators and Major Depressive Disorder Outcome. Twin Research and Human Genetics, 28 (3), 1-9. doi: 10.1017/thg.2025.10011

Exploring the Relationship between Polygenic Scores, Community-Shared Socioeconomic Indicators and Major Depressive Disorder Outcome

2025

Journal Article

Efficacy and safety of semaglutide versus placebo for people with schizophrenia on clozapine with obesity (COaST): a phase 2, multi-centre, participant and investigator- blinded, randomised controlled trial in Australia

Siskind, Dan, Baker, Andrea, Arnautovska, Urska, Warren, Nicola, Russell, Anthony, DeMonte, Veronica, Halstead, Sean, Iyer, Ravi, Korman, Nicole, McKeon, Gemma, Medland, Sarah, Parker, Stephen, Stedman, Terry and Trott, Mike (2025). Efficacy and safety of semaglutide versus placebo for people with schizophrenia on clozapine with obesity (COaST): a phase 2, multi-centre, participant and investigator- blinded, randomised controlled trial in Australia. The Lancet Psychiatry, 12 (7), 493-503. doi: 10.1016/S2215-0366(25)00129-4

Efficacy and safety of semaglutide versus placebo for people with schizophrenia on clozapine with obesity (COaST): a phase 2, multi-centre, participant and investigator- blinded, randomised controlled trial in Australia

2025

Conference Publication

Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity

Du-Harpur, Xinyi, Maxwell, Jessye, Mitchell, Brittany L., Pardo, Luba M, Witkam, Willemijn C. A. M., Dand, Nick, Bartels, Meike, Betti, Michael, Boomsma, Dorret I., Dong, Xianjun, Gerring, Zachary, Finer, Sarah, Hagenbeek, Fiona A., Hottenga, Jouke Jan, Hripcsak, George, Huilaja, Laura, Hveem, Kristian, Jacobs, Benjamin, Kals, Mart, Kaufman-Cook, James, Kettunen, Johannes, Khan, Atlas, Kingo, Kulli, Kiryluk, Krzysztof, Løset, Mari, Lunter, Gerton, Lupton, Michelle, Min, Josine L., Martin, Nicholas G. ... Simpson, Michael A. (2025). Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity. 105th Annual Meeting of the British Association of Dermatologists, Glasgow, United Kingdom, 1-3 July 2025. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/bjd/ljaf085.025

Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity

2025

Journal Article

Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling

Sunny, Sharon, Cheng, Guo, Haria, Joshua, Nazari, Iman, Chauhan, Jagmohan and Ennis, Sarah (2025). Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling. Mammalian Genome, 36 (3), 914-927. doi: 10.1007/s00335-025-10140-0

Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling

2025

Journal Article

Dissecting causal relationships between cortical morphology and neuropsychiatric disorders: a bidirectional Mendelian randomization study

Lin, Bochao Danae, Li, Yunzhi, Goula, Anastasia A., Chang, Xiao, Grasby, Katrina L., Medland, Sarah, Andreassen, Ole A., Rutten, Bart P. F., Guloksuz, Sinan, van der Meer, Dennis and Luykx, Jurjen J. (2025). Dissecting causal relationships between cortical morphology and neuropsychiatric disorders: a bidirectional Mendelian randomization study. Nature Mental Health, 3 (6) 447, 613-625. doi: 10.1038/s44220-025-00397-4

Dissecting causal relationships between cortical morphology and neuropsychiatric disorders: a bidirectional Mendelian randomization study

2025

Journal Article

Genetic links between subcortical brain morphometry and suicide attempt risk in children and adults

Ceja, Zuriel, García‐Marín, Luis M., Hung, I‐Tzu, Medland, Sarah E., Edwards, Alexis C., Rentería, Miguel E. and Rabinowitz, Jill A. (2025). Genetic links between subcortical brain morphometry and suicide attempt risk in children and adults. Human Brain Mapping, 46 (7) e70220. doi: 10.1002/hbm.70220

Genetic links between subcortical brain morphometry and suicide attempt risk in children and adults

2025

Journal Article

Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI

Zhu, Alyssa H., Nir, Talia M., Javid, Shayan, Villalón-Reina, Julio E., Rodrigue, Amanda L., Strike, Lachlan T., de Zubicaray, Greig I., McMahon, Katie L., Wright, Margaret J., Medland, Sarah E., Blangero, John, Glahn, David C., Kochunov, Peter, Williamson, Douglas E., Håberg, Asta K., Thompson, Paul M. and Jahanshad, Neda (2025). Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI. Scientific Data, 12 (1) 748, 748. doi: 10.1038/s41597-025-05028-2

Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI

Availability

Honorary Professor Sarah Medland is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.

    Principal Advisor

  • Master Philosophy

    Novel efficient statistical methods for biobank-scale prediction from brain imaging

    Principal Advisor

  • Doctor Philosophy

    Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    Genetic architecture of differences in symptomatology and treatment response in major depressive disorder

    Principal Advisor

    Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería

  • Doctor Philosophy

    Genetic and environmental risk factors influencing mood disorders

    Principal Advisor

Completed supervision

Enquiries

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