Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2022
Conference Publication
Differentiation of unipolar and bipolar depression based on clinical features: a systematic review and meta-analysis.
Hopkins, Kristen, Siskind, Dan, McMahon, Laura, Philips, Elise, Lind, Penelope, Medland, Sarah and Warren, Nicola (2022). Differentiation of unipolar and bipolar depression based on clinical features: a systematic review and meta-analysis.. The 24th Annual Conference of the International Society for Bipolar Disorders, Online, 10–12 June 2022. Hoboken, NJ United States: Wiley-Blackwell.
2022
Journal Article
Lifetime prevalence and correlates of perinatal depression in a case-cohort study of depression
Kiewa, Jacqueline, Meltzer-Brody, Samantha, Milgrom, Jeannette, Bennett, Elizabeth, Mackle, Tracey, Guintivano, Jerry, Hickie, Ian B, Colodro-Conde, Lucia, Medland, Sarah E, Martin, Nick, Wray, Naomi and Byrne, Enda (2022). Lifetime prevalence and correlates of perinatal depression in a case-cohort study of depression. BMJ Open, 12 (8) e059300, 1-7. doi: 10.1136/bmjopen-2021-059300
2022
Journal Article
Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults
Crouse, Jacob J., Ho, Nicholas, Scott, Jan, Parker, Richard, Park, Shin Ho, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Byrne, Enda M., Hermens, Daniel F., Medland, Sarah E., Martin, Nicholas G., Gillespie, Nathan A. and Hickie, Ian B. (2022). Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults. European Psychiatry, 65 (1) e32, 1-24. doi: 10.1192/j.eurpsy.2022.23
2022
Journal Article
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Howe, Laurence J., Nivard, Michel G., Morris, Tim T., Hansen, Ailin F., Rasheed, Humaira, Cho, Yoonsu, Chittoor, Geetha, Ahlskog, Rafael, Lind, Penelope A., Palviainen, Teemu, van der Zee, Matthijs D., Cheesman, Rosa, Mangino, Massimo, Wang, Yunzhang, Li, Shuai, Klaric, Lucija, Ratliff, Scott M., Bielak, Lawrence F., Nygaard, Marianne, Giannelis, Alexandros, Willoughby, Emily A., Reynolds, Chandra A., Balbona, Jared V., Andreassen, Ole A., Ask, Helga, Baras, Aris, Bauer, Christopher R., Boomsma, Dorret I., Campbell, Archie ... Within Family Consortium (2022). Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects. Nature Genetics, 54 (5), 581-592. doi: 10.1038/s41588-022-01062-7
2022
Journal Article
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Brouwer, Rachel M., Klein, Marieke, Grasby, Katrina L., Schnack, Hugo G., Jahanshad, Neda, Teeuw, Jalmar, Thomopoulos, Sophia I., Sprooten, Emma, Franz, Carol E., Gogtay, Nitin, Kremen, William S., Panizzon, Matthew S., Olde Loohuis, Loes M., Whelan, Christopher D., Aghajani, Moji, Alloza, Clara, Alnæs, Dag, Artiges, Eric, Ayesa-Arriola, Rosa, Barker, Gareth J., Bastin, Mark E., Blok, Elisabet, Bøen, Erlend, Breukelaar, Isabella A., Bright, Joanna K., Buimer, Elizabeth E. L., Bülow, Robin, Cannon, Dara M., Ciufolini, Simone ... the IMAGEN Consortium (2022). Genetic variants associated with longitudinal changes in brain structure across the lifespan. Nature Neuroscience, 25 (4), 421-432. doi: 10.1038/s41593-022-01042-4
2022
Journal Article
DNA methylation in peripheral tissues and left-handedness
Odintsova, Veronika V., Suderman, Matthew, Hagenbeek, Fiona A., Caramaschi, Doretta, Hottenga, Jouke-Jan, Pool, René, Dolan, Conor V., Ligthart, Lannie, van Beijsterveldt, Catharina E M, Willemsen, Gonneke, de Geus, Eco J C, Beck, Jeffrey J., Ehli, Erik A., Cuellar-Partida, Gabriel, Evans, David M., Medland, Sarah E., Relton, Caroline L., Boomsma, Dorret I. and van Dongen, Jenny (2022). DNA methylation in peripheral tissues and left-handedness. Scientific Reports, 12 (1) 5606, 5606. doi: 10.1038/s41598-022-08998-0
2022
Journal Article
Genetic and environmental influences on biological essentialism, heuristic thinking, need for closure, and conservative values: insights from a survey and twin study
Morosoli, J. J., Barlow, F. K., Colodro-Conde, L. and Medland, S. E. (2022). Genetic and environmental influences on biological essentialism, heuristic thinking, need for closure, and conservative values: insights from a survey and twin study. Behavior Genetics, 52 (3), 170-183. doi: 10.1007/s10519-022-10101-2
2022
Journal Article
censusADHD Study: an Australian-wide medication-based recruitment study for Attention-Deficit/Hyperactivity Disorder
Lind, Penelope A. and Medland, Sarah E. (2022). censusADHD Study: an Australian-wide medication-based recruitment study for Attention-Deficit/Hyperactivity Disorder. Australian & New Zealand Journal of Psychiatry, 57 (2) ARTN 00048674221089234, 1-12. doi: 10.1177/00048674221089234
2022
Journal Article
Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression
Kiewa, Jacqueline, Meltzer‐Brody, Samantha, Milgrom, Jeanette, Guintivano, Jerry, Hickie, Ian B., Whiteman, David C., Olsen, Catherine M., Colodro‐Conde, Lucía, Medland, Sarah E., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2022). Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression. Depression and Anxiety, 39 (3), 182-191. doi: 10.1002/da.23232
2022
Journal Article
Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use
Rabinowitz, Jill A., Campos, Adrian I., Ong, Jue-Sheng, García-Marín, Luis M., Alcauter, Sarael, Mitchell, Brittany L, Grasby, Katrina L, Cuéllar-Partida, Gabriel, Gillespie, Nathan A, Huhn, Andrew S, Martin, Nicholas G, Thompson, Paul M, Medland, Sarah E, Maher, Brion S and Rentería, Miguel E (2022). Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use. Cerebral Cortex, 32 (4), 796-807. doi: 10.1093/cercor/bhab243
2022
Journal Article
Subtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium
Sha, Zhiqiang, van Rooij, Daan, Anagnostou, Evdokia, Arango, Celso, Auzias, Guillaume, Behrmann, Marlene, Bernhardt, Boris, Bolte, Sven, Busatto, Geraldo F., Calderoni, Sara, Calvo, Rosa, Daly, Eileen, Deruelle, Christine, Duan, Meiyu, Duran, Fabio Luis Souza, Durston, Sarah, Ecker, Christine, Ehrlich, Stefan, Fair, Damien, Fedor, Jennifer, Fitzgerald, Jacqueline, Floris, Dorothea L., Franke, Barbara, Freitag, Christine M., Gallagher, Louise, Glahn, David C., Haar, Shlomi, Hoekstra, Liesbeth, Jahanshad, Neda ... Francks, Clyde (2022). Subtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium. Molecular Psychiatry, 27 (4), 2114-2125. doi: 10.1038/s41380-022-01452-7
2022
Journal Article
Australian Parkinson’s Genetics Study (APGS): pilot (n=1532)
Bivol, Svetlana, Mellick, George D., Gratten, Jacob, Parker, Richard, Mulcahy, Aoibhe, Mosley, Philip E., Poortvliet, Peter C., Campos, Adrian I., Mitchell, Brittany L., Garcia-Marin, Luis M., Cross, Simone, Ferguson, Mary, Lind, Penelope A., Loesch, Danuta Z., Visscher, Peter M., Medland, Sarah E., Scherzer, Clemens R., Martin, Nicholas G. and Rentería, Miguel E. (2022). Australian Parkinson’s Genetics Study (APGS): pilot (n=1532). BMJ Open, 12 (2) e052032, e052032. doi: 10.1136/bmjopen-2021-052032
2022
Journal Article
Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study
Campos, Adrian I., Byrne, Enda M., Mitchell, Brittany L., Wray, Naomi R., Lind, Penelope A., Licinio, Julio, Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2022). Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study. The Pharmacogenomics Journal, 22 (2), 130-135. doi: 10.1038/s41397-022-00267-7
2022
Journal Article
Limb development genes underlie variation in human fingerprint patterns
Li, Jinxi, Glover, James D., Zhang, Haiguo, Peng, Meifang, Tan, Jingze, Mallick, Chandana Basu, Hou, Dan, Yang, Yajun, Wu, Sijie, Liu, Yu, Peng, Qianqian, Zheng, Shijie C., Crosse, Edie I., Medvinsky, Alexander, Anderson, Richard A., Brown, Helen, Yuan, Ziyu, Zhou, Shen, Xu, Yanqing, Kemp, John P., Ho, Yvonne Y.W., Loesch, Danuta Z., Wang, Lizhong, Li, Yingxiang, Tang, Senwei, Wu, Xiaoli, Walters, Robin G., Lin, Kuang, Meng, Ruogu ... Wang, Sijia (2022). Limb development genes underlie variation in human fingerprint patterns. Cell, 185 (1), 95-112.e18. doi: 10.1016/j.cell.2021.12.008
2022
Journal Article
Bridging the gap: Short structural variants in the genetics of anorexia nervosa
Berthold, Natasha, Pytte, Julia, Bulik, Cynthia M., Tschochner, Monika, Medland, Sarah E. and Akkari, Patrick Anthony (2022). Bridging the gap: Short structural variants in the genetics of anorexia nervosa. International Journal of Eating Disorders, 55 (6), 747-753. doi: 10.1002/eat.23716
2022
Conference Publication
Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank
Nir, Talia M., Zhu, Alyssa H., Gari, Iyad Ba, Dixon, Daniel, Islam, Tasfiya, Villalon-Reina, Julio E., Medland, Sarah E., Thompson, Paul M. and Jahanshad, Neda (2022). Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank. Pacific Symposium on Biocomputing 2022, Kohala Coast, HI United States, 3 – 7 January 2022. Singapore: World Scientific Publishing. doi: 10.1142/9789811250477_0012
2021
Journal Article
Comparing empirical kinship derived heritability for imaging genetics traits in the UK biobank and human connectome project
Gao, Si, Donohue, Brian, Hatch, Kathryn S., Chen, Shuo, Ma, Tianzhou, Ma, Yizhou, Kvarta, Mark D., Bruce, Heather, Adhikari, Bhim M., Jahanshad, Neda, Thompson, Paul M., Blangero, John, Hong, L. Elliot, Medland, Sarah E., Ganjgahi, Habib, Nichols, Thomas E. and Kochunov, Peter (2021). Comparing empirical kinship derived heritability for imaging genetics traits in the UK biobank and human connectome project. NeuroImage, 245 118700, 1-11. doi: 10.1016/j.neuroimage.2021.118700
2021
Journal Article
Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD
García-Marín, Luis M., Campos, Adrián I., Cuéllar-Partida, Gabriel, Medland, Sarah E., Kollins, Scott H. and Rentería, Miguel E. (2021). Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD. Scientific Reports, 11 (1) 22628, 22628. doi: 10.1038/s41598-021-01517-7
2021
Journal Article
Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume
Zheng, Yuanchao, Garrett, Melanie E., Sun, Delin, Clarke-Rubright, Emily K., Haswell, Courtney C., Maihofer, Adam X., Elman, Jeremy A., Franz, Carol E., Lyons, Michael J., Kremen, William S., Peverill, Matthew, Sambrook, Kelly, McLaughlin, Katie A., Davenport, Nicholas D., Disner, Seth, Sponheim, Scott R., Andrew, Elpiniki, Korgaonkar, Mayuresh, Bryant, Richard, Varkevisser, Tim, Geuze, Elbert, Coleman, Jonathan, Beckham, Jean C., Kimbrel, Nathan A., Sullivan, Danielle, Miller, Mark, Hayes, Jasmeet, Verfaellie, Mieke, Wolf, Erika ... Morey, Rajendra A. (2021). Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume. Translational Psychiatry, 11 (1) 637, 637. doi: 10.1038/s41398-021-01707-x
2021
Journal Article
Understanding genetic risk factors for common side effects of antidepressant medications
Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Principal Advisor
Other advisors: Professor Nick Martin
-
Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Doctor Philosophy
Genetics of affective disorders, personality traits, and responses to treatment
Associate Advisor
-
Doctor Philosophy
Statistical Genetic Analyses of Major Depressive Disorder
Associate Advisor
Completed supervision
-
2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
-
2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
-
2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
-
2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
-
2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
-
2016
Doctor Philosophy
Complex trait genetics: mapping, correlation and causation
Associate Advisor
Other advisors: Professor Grant Montgomery
-
2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
-
2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
Enquiries
For media enquiries about Honorary Professor Sarah Medland's areas of expertise, story ideas and help finding experts, contact our Media team: