Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2022
Journal Article
Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use
Rabinowitz, Jill A., Campos, Adrian I., Ong, Jue-Sheng, García-Marín, Luis M., Alcauter, Sarael, Mitchell, Brittany L, Grasby, Katrina L, Cuéllar-Partida, Gabriel, Gillespie, Nathan A, Huhn, Andrew S, Martin, Nicholas G, Thompson, Paul M, Medland, Sarah E, Maher, Brion S and Rentería, Miguel E (2022). Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use. Cerebral Cortex, 32 (4), 796-807. doi: 10.1093/cercor/bhab243
2022
Journal Article
Subtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium
Sha, Zhiqiang, van Rooij, Daan, Anagnostou, Evdokia, Arango, Celso, Auzias, Guillaume, Behrmann, Marlene, Bernhardt, Boris, Bolte, Sven, Busatto, Geraldo F., Calderoni, Sara, Calvo, Rosa, Daly, Eileen, Deruelle, Christine, Duan, Meiyu, Duran, Fabio Luis Souza, Durston, Sarah, Ecker, Christine, Ehrlich, Stefan, Fair, Damien, Fedor, Jennifer, Fitzgerald, Jacqueline, Floris, Dorothea L., Franke, Barbara, Freitag, Christine M., Gallagher, Louise, Glahn, David C., Haar, Shlomi, Hoekstra, Liesbeth, Jahanshad, Neda ... Francks, Clyde (2022). Subtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium. Molecular Psychiatry, 27 (4), 2114-2125. doi: 10.1038/s41380-022-01452-7
2022
Journal Article
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors
Mullins, Niamh, Kang, JooEun, Campos, Adrian I., Coleman, Jonathan R I, Edwards, Alexis C., Galfalvy, Hanga, Levey, Daniel F., Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J., Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D., Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B., Bergen, Andrew W., Berrettini, Wade H., Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J., Chen, Hsi-Chung ... Ruderfer, Douglas M. (2022). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors. Biological Psychiatry, 91 (3), 313-327. doi: 10.1016/j.biopsych.2021.05.029
2022
Journal Article
Australian Parkinson’s Genetics Study (APGS): pilot (n=1532)
Bivol, Svetlana, Mellick, George D., Gratten, Jacob, Parker, Richard, Mulcahy, Aoibhe, Mosley, Philip E., Poortvliet, Peter C., Campos, Adrian I., Mitchell, Brittany L., Garcia-Marin, Luis M., Cross, Simone, Ferguson, Mary, Lind, Penelope A., Loesch, Danuta Z., Visscher, Peter M., Medland, Sarah E., Scherzer, Clemens R., Martin, Nicholas G. and Rentería, Miguel E. (2022). Australian Parkinson’s Genetics Study (APGS): pilot (n=1532). BMJ Open, 12 (2) e052032, e052032. doi: 10.1136/bmjopen-2021-052032
2022
Journal Article
Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study
Campos, Adrian I., Byrne, Enda M., Mitchell, Brittany L., Wray, Naomi R., Lind, Penelope A., Licinio, Julio, Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2022). Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study. The Pharmacogenomics Journal, 22 (2), 130-135. doi: 10.1038/s41397-022-00267-7
2022
Journal Article
Limb development genes underlie variation in human fingerprint patterns
Li, Jinxi, Glover, James D., Zhang, Haiguo, Peng, Meifang, Tan, Jingze, Mallick, Chandana Basu, Hou, Dan, Yang, Yajun, Wu, Sijie, Liu, Yu, Peng, Qianqian, Zheng, Shijie C., Crosse, Edie I., Medvinsky, Alexander, Anderson, Richard A., Brown, Helen, Yuan, Ziyu, Zhou, Shen, Xu, Yanqing, Kemp, John P., Ho, Yvonne Y.W., Loesch, Danuta Z., Wang, Lizhong, Li, Yingxiang, Tang, Senwei, Wu, Xiaoli, Walters, Robin G., Lin, Kuang, Meng, Ruogu ... Wang, Sijia (2022). Limb development genes underlie variation in human fingerprint patterns. Cell, 185 (1), 95-112.e18. doi: 10.1016/j.cell.2021.12.008
2022
Conference Publication
Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank
Nir, Talia M., Zhu, Alyssa H., Gari, Iyad Ba, Dixon, Daniel, Islam, Tasfiya, Villalon-Reina, Julio E., Medland, Sarah E., Thompson, Paul M. and Jahanshad, Neda (2022). Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank. Pacific Symposium on Biocomputing 2022, Kohala Coast, HI United States, 3 – 7 January 2022. Singapore: World Scientific Publishing. doi: 10.1142/9789811250477_0012
2022
Journal Article
Bridging the gap: Short structural variants in the genetics of anorexia nervosa
Berthold, Natasha, Pytte, Julia, Bulik, Cynthia M., Tschochner, Monika, Medland, Sarah E. and Akkari, Patrick Anthony (2022). Bridging the gap: Short structural variants in the genetics of anorexia nervosa. International Journal of Eating Disorders, 55 (6), 747-753. doi: 10.1002/eat.23716
2021
Journal Article
Comparing empirical kinship derived heritability for imaging genetics traits in the UK biobank and human connectome project
Gao, Si, Donohue, Brian, Hatch, Kathryn S., Chen, Shuo, Ma, Tianzhou, Ma, Yizhou, Kvarta, Mark D., Bruce, Heather, Adhikari, Bhim M., Jahanshad, Neda, Thompson, Paul M., Blangero, John, Hong, L. Elliot, Medland, Sarah E., Ganjgahi, Habib, Nichols, Thomas E. and Kochunov, Peter (2021). Comparing empirical kinship derived heritability for imaging genetics traits in the UK biobank and human connectome project. NeuroImage, 245 118700, 1-11. doi: 10.1016/j.neuroimage.2021.118700
2021
Journal Article
Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD
García-Marín, Luis M., Campos, Adrián I., Cuéllar-Partida, Gabriel, Medland, Sarah E., Kollins, Scott H. and Rentería, Miguel E. (2021). Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD. Scientific Reports, 11 (1) 22628, 22628. doi: 10.1038/s41598-021-01517-7
2021
Journal Article
Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume
Zheng, Yuanchao, Garrett, Melanie E., Sun, Delin, Clarke-Rubright, Emily K., Haswell, Courtney C., Maihofer, Adam X., Elman, Jeremy A., Franz, Carol E., Lyons, Michael J., Kremen, William S., Peverill, Matthew, Sambrook, Kelly, McLaughlin, Katie A., Davenport, Nicholas D., Disner, Seth, Sponheim, Scott R., Andrew, Elpiniki, Korgaonkar, Mayuresh, Bryant, Richard, Varkevisser, Tim, Geuze, Elbert, Coleman, Jonathan, Beckham, Jean C., Kimbrel, Nathan A., Sullivan, Danielle, Miller, Mark, Hayes, Jasmeet, Verfaellie, Mieke, Wolf, Erika ... Morey, Rajendra A. (2021). Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume. Translational Psychiatry, 11 (1) 637, 637. doi: 10.1038/s41398-021-01707-x
2021
Journal Article
Understanding genetic risk factors for common side effects of antidepressant medications
Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8
2021
Journal Article
Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3
Nolan, James, Campbell, Purdey J, Brown, Suzanne J, Zhu, Gu, Gordon, Scott, Lim, Ee Mun, Joseph, John, Cross, Simone M, Panicker, Vijay, Medland, Sarah E, Melton, Phillip E, Beilin, Lawrence J, Mori, Trevor A, Mullin, Benjamin H, Pennell, Craig E, Wang, Carol A, Dudbridge, Frank, Walsh, John P, Martin, Nicholas G and Wilson, Scott G (2021). Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3. European Journal of Endocrinology, 185 (5), 743-753. doi: 10.1530/EJE-21-0614
2021
Journal Article
The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes
Mitchell, Brittany L., Campos, Adrian I., Whiteman, David C., Olsen, Catherine M., Gordon, Scott D., Walker, Adam J., Dean, Olivia M., Berk, Michael, Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G. and Byrne, Enda M. (2021). The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes. Biological Psychiatry, 92 (3), 227-235. doi: 10.1016/j.biopsych.2021.10.021
2021
Journal Article
Investigating perceived heritability of mental health disorders and attitudes toward genetic testing in the United States, United Kingdom, and Australia
Morosoli, José Juan, Colodro‐Conde, Lucía, Barlow, Fiona Kate and Medland, Sarah E. (2021). Investigating perceived heritability of mental health disorders and attitudes toward genetic testing in the United States, United Kingdom, and Australia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186 (6), 341-352. doi: 10.1002/ajmg.b.32875
2021
Journal Article
Polygenic risk scores derived from varying definitions of depression and risk of depression
Mitchell, Brittany L., Thorp, Jackson G., Wu, Yeda, Campos, Adrian I., Nyholt, Dale R., Gordon, Scott D., Whiteman, David C., Olsen, Catherine M., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Wray, Naomi R. and Byrne, Enda M. (2021). Polygenic risk scores derived from varying definitions of depression and risk of depression. JAMA Psychiatry, 78 (10), 1152-1160. doi: 10.1001/jamapsychiatry.2021.1988
2021
Journal Article
Genetic insights into biological mechanisms governing human ovarian ageing
Ruth, Katherine S., Day, Felix R., Hussain, Jazib, Martínez-Marchal, Ana, Aiken, Catherine E., Azad, Ajuna, Thompson, Deborah J., Knoblochova, Lucie, Abe, Hironori, Tarry-Adkins, Jane L., Gonzalez, Javier Martin, Fontanillas, Pierre, Claringbould, Annique, Bakker, Olivier B., Sulem, Patrick, Walters, Robin G., Terao, Chikashi, Turon, Sandra, Horikoshi, Momoko, Lin, Kuang, Onland-Moret, N. Charlotte, Sankar, Aditya, Hertz, Emil Peter Thrane, Timshel, Pascal N., Shukla, Vallari, Borup, Rehannah, Olsen, Kristina W., Aguilera, Paula, Ferrer-Roda, Mònica ... Perry, John R. B. (2021). Genetic insights into biological mechanisms governing human ovarian ageing. Nature, 596 (7872), 393-397. doi: 10.1038/s41586-021-03779-7
2021
Journal Article
Genetic association study of childhood aggression across raters, instruments, and age
Ip, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, Nolte, Ilja M., St Pourcain, Beate, Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Colodro-Conde, Lucía, Gordon, Scott, Zayats, Tetyana, Aliev, Fazil, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Seppälä, Ilkka, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S., Day, Felix R., Hottenga, Jouke-Jan ... Boomsma, Dorret I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11 (1) 413, 413. doi: 10.1038/s41398-021-01480-x
2021
Journal Article
Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype
Campos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) 00048674211031491, 1-10. doi: 10.1177/00048674211031491
2021
Journal Article
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Mullins, Niamh, Forstner, Andreas J., O'Connell, Kevin S., Coombes, Brandon, Coleman, Jonathan R I, Qiao, Zhen, Als, Thomas D., Bigdeli, Tim B., Børte, Sigrid, Bryois, Julien, Charney, Alexander W., Drange, Ole Kristian, Gandal, Michael J., Hagenaars, Saskia P., Ikeda, Masashi, Kamitaki, Nolan, Kim, Minsoo, Krebs, Kristi, Panagiotaropoulou, Georgia, Schilder, Brian M., Sloofman, Laura G., Steinberg, Stacy, Trubetskoy, Vassily, Winsvold, Bendik S., Won, Hong-Hee, Abramova, Liliya, Adorjan, Kristina, Agerbo, Esben, Al Eissa, Mariam ... Andreassen, Ole A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature genetics, 53 (6), 817-829. doi: 10.1038/s41588-021-00857-4
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Principal Advisor
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Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Principal Advisor
Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería
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Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
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Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
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2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
-
2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
-
2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
Enquiries
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