Honorary Professor

Sarah Medland

Email: 

Background

Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.

Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.

ORCID: 0000-0003-1382-380X

ResearcherID: C-7630-2013

Scopus Author ID: 34571085600

Email: sarah.medland@qimrberghofer.edu.au

Qualifications

2006 PhD (Psychology), University of Queensland

Dean's Award for Outstanding Research Higher Degree Thesis

2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)

Availability

Honorary Professor Sarah Medland is:
Available for supervision

Fields of research

Applied economics Psychology

Search Professor Sarah Medland’s works on UQ eSpace

531 works between 2001 and 2025
All (531) Journal Article (449) Other Outputs (1) Conference Publication (76) Book Chapter (5)

81 - 100 of 531 works

2023

Journal Article

Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study

Howe, Laurence J., Rasheed, Humaira, Jones, Paul R., Boomsma, Dorret I., Evans, David M., Giannelis, Alexandros, Hayward, Caroline, Hopper, John L., Hughes, Amanda, Lahtinen, Hannu, Li, Shuai, Lind, Penelope A., Martin, Nicholas G., Martikainen, Pekka, Medland, Sarah E., Morris, Tim T., Nivard, Michel G., Pingault, Jean-Baptiste, Silventoinen, Karri, Smith, Jennifer A., Willoughby, Emily A., Wilson, James F., Ahlskog, Rafael, Andreassen, Ole A., Ask, Helga, Campbell, Archie, Cheesman, Rosa, Cho, Yoonsu, Christensen, Kaare ... Within Family Consortium (2023). Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study. International Journal of Epidemiology, 52 (5), 1579-1591. doi: 10.1093/ije/dyad079

Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study

2023

Journal Article

Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers

Boen, Rune, Kaufmann, Tobias, van der Meer, Dennis, Frei, Oleksandr, Agartz, Ingrid, Ames, David, Andersson, Micael, Armstrong, Nicola J., Artiges, Eric, Atkins, Joshua R., Bauer, Jochen, Benedetti, Francesco, Boomsma, Dorret I., Brodaty, Henry, Brosch, Katharina, Buckner, Randy L., Cairns, Murray J., Calhoun, Vince, Caspers, Svenja, Cichon, Sven, Corvin, Aiden P., Facorro, Benedicto Crespo, Dannlowski, Udo, David, Friederike S., de Geus, Eco J.C., de Zubicaray, Greig I., Desrivières, Sylvane, Doherty, Joanne L., Donohoe, Gary ... Sonderby, Ida E. (2023). Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers. Biological Psychiatry, 95 (2), 147-160. doi: 10.1016/j.biopsych.2023.08.018

Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers

2023

Journal Article

Effects of semaglutide on body weight in clozapine-treated people with schizophrenia and obesity: study protocol for a placebo-controlled, randomised multicentre trial (COaST)

Siskind, Dan, Baker, Andrea, Russell, Anthony, Warren, Nicola, Robinson, Gail, Parker, Stephen, Medland, Sarah, Kisely, Steve, Hager, Tineka and Arnautovska, Urska (2023). Effects of semaglutide on body weight in clozapine-treated people with schizophrenia and obesity: study protocol for a placebo-controlled, randomised multicentre trial (COaST). BJPsych Open, 9 (4) e136, 1-6. doi: 10.1192/bjo.2023.532

Effects of semaglutide on body weight in clozapine-treated people with schizophrenia and obesity: study protocol for a placebo-controlled, randomised multicentre trial (COaST)

2023

Journal Article

Supervised Machine Learning Classifies Inflammatory Bowel Disease Patients by Subtype Using Whole Exome Sequencing Data

Stafford, Imogen S., Ashton, James J., Mossotto, Enrico, Cheng, Guo, Beattie, R. Mark and Ennis, Sarah (2023). Supervised Machine Learning Classifies Inflammatory Bowel Disease Patients by Subtype Using Whole Exome Sequencing Data. Journal of Crohns & Colitis, 17 (10), 1672-1680. doi: 10.1093/ecco-jcc/jjad084

Supervised Machine Learning Classifies Inflammatory Bowel Disease Patients by Subtype Using Whole Exome Sequencing Data

2023

Journal Article

A genotype-to-phenotype approach suggests under-reporting of single nucleotide variants in nephrocystin-1 (NPHP1) related disease (UK 100,000 Genomes Project)

Leggatt, Gary, Cheng, Guo, Narain, Sumit, Briseno-Roa, Luis, Annereau, Jean-Philippe, Gast, Christine, Gilbert, Rodney D. and Ennis, Sarah (2023). A genotype-to-phenotype approach suggests under-reporting of single nucleotide variants in nephrocystin-1 (NPHP1) related disease (UK 100,000 Genomes Project). Scientific Reports, 13 (1) 9369, 1-12. doi: 10.1038/s41598-023-32169-4

A genotype-to-phenotype approach suggests under-reporting of single nucleotide variants in nephrocystin-1 (NPHP1) related disease (UK 100,000 Genomes Project)

2023

Journal Article

“Echoes of a dark past” is a history of maternal childhood maltreatment a perinatal risk factor for pregnancy and postpartum trauma experiences? A longitudinal study

Mackle, Tracey, Colodro-Conde, Lucía, de Dassel, Therese, Braun, Anastasia, Pope, Adele, Bennett, Elizabeth, Kothari, Alka, Bruxner, George, Medland, Sarah E. and Patterson, Sue (2023). “Echoes of a dark past” is a history of maternal childhood maltreatment a perinatal risk factor for pregnancy and postpartum trauma experiences? A longitudinal study. BMC Pregnancy and Childbirth, 23 (1) 397, 1-12. doi: 10.1186/s12884-023-05714-2

“Echoes of a dark past” is a history of maternal childhood maltreatment a perinatal risk factor for pregnancy and postpartum trauma experiences? A longitudinal study

2023

Conference Publication

Childhood Trauma Exposure and PTSD Diagnosis Interact With Polygenic Determinants of Hippocampal and Amygdala Volume

Logue, Mark, Zheng, Yuanchao, Garrett, Melanie, Maihofer, Adam, Clarke, Emily, Haswell, Courtney, Sun, Delin, Peverill, Matthew, McLaughlin, Katie, Sambrook, Kelly, Davenport, Nicholas, Disner, Seth, Korgaonkar, Mayuresh, Bryant, Richard, Varkevisser, Tim, Geuze, Elbert, Beckham, Jean, Kimbrel, Nathan, Coleman, Jonathan, Sullivan, Danielle, Wolf, Erika, Hayes, Jasmeet, Verfaellie, Mieke, Salat, David, Spielberg, Jeffrey M., McGlinchey, Regina, Milberg, William, Medland, Sarah E., Nievergelt, Caroline ... Morey, Rajendra (2023). Childhood Trauma Exposure and PTSD Diagnosis Interact With Polygenic Determinants of Hippocampal and Amygdala Volume. 78th Annual Meeting of the Society of Biological Psychiatry, San Diego, CA United States, 27-29 April 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.biopsych.2023.02.056

Childhood Trauma Exposure and PTSD Diagnosis Interact With Polygenic Determinants of Hippocampal and Amygdala Volume

2023

Journal Article

A palindrome-like structure on 16p13.3 is associated with the formation of complex structural variations and SRRM2 haploinsufficiency

Pagnamenta, Alistair T. T., Yu, Jing, Willis, Tracey A. A., Hashim, Mona, Seaby, Eleanor G. G., Walker, Susan, Xian, Jiaqi, Cheng, Emily W. Y., Tavares, Ana Lisa Taylor, Forzano, Francesca, Cox, Helen, Dabir, Tabib, Brady, Angela F. F., Ghali, Neeti, Atanur, Santosh S. S., Ennis, Sarah, Baralle, Diana and Taylor, Jenny C. C. (2023). A palindrome-like structure on 16p13.3 is associated with the formation of complex structural variations and SRRM2 haploinsufficiency. Human Mutation, 2023 6633248, 1-9. doi: 10.1155/2023/6633248

A palindrome-like structure on 16p13.3 is associated with the formation of complex structural variations and SRRM2 haploinsufficiency

2023

Journal Article

Large- scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

Schijven, Dick, Postema, Merel C., Fukunaga, Masaki, Matsumoto, Junya, Miura, Kenichiro, de Zwarte, Sonja M. C., van Haren, Neeltje E. M., Cahn, Wiepke, Pol, Hilleke E. Hulshoff, Kahn, Rene S., Ayesa-Arriola, Rosa, de la Foz, Victor Ortiz-Garcia, Tordesillas-Gutierrez, Diana, Vazquez-Bourgon, Javier, Crespo-Facorro, Benedicto, Alnaes, Dag, Dahl, Andreas, Westlye, Lars T., Agartz, Ingrid, Andreassen, Ole A., Jonsson, Erik G., Kochunov, Peter, Bruggemann, Jason M., Catts, Stanley V., Michie, Patricia T., Mowry, Bryan J., Quide, Yann, Rasser, Paul E., Schall, Ulrich ... ENIGMA consortium (2023). Large- scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium. Proceedings of the National Academy of Sciences of the United States of America, 120 (14) e2213880120, 1-12. doi: 10.1073/pnas.2213880120

Large- scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

2023

Journal Article

The association between trauma exposure, polygenic risk and individual depression symptoms

Thorp, Jackson G., Gerring, Zachary F., Colodro-Conde, Lucía, Byrne, Enda M., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2023). The association between trauma exposure, polygenic risk and individual depression symptoms. Psychiatry Research, 321 115101, 1-8. doi: 10.1016/j.psychres.2023.115101

The association between trauma exposure, polygenic risk and individual depression symptoms

2023

Journal Article

Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

Demontis, Ditte, Walters, G. Bragi, Athanasiadis, Georgios, Walters, Raymond, Therrien, Karen, Nielsen, Trine Tollerup, Farajzadeh, Leila, Voloudakis, Georgios, Bendl, Jaroslav, Zeng, Biau, Zhang, Wen, Grove, Jakob, Als, Thomas D., Duan, Jinjie, Satterstrom, F. Kyle, Bybjerg-Grauholm, Jonas, Bækved-Hansen, Marie, Gudmundsson, Olafur O., Magnusson, Sigurdur H., Baldursson, Gisli, Davidsdottir, Katrin, Haraldsdottir, Gyda S., Agerbo, Esben, Hoffman, Gabriel E., Dalsgaard, Søren, Martin, Jonna, Ribasés, Marta, Boomsma, Dorret I., Soler Artigas, Maria ... iPSYCH-Broad Consortium (2023). Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics, 55 (4), 730-730. doi: 10.1038/s41588-023-01350-w

Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

2023

Journal Article

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

Demontis, Ditte, Walters, G. Bragi, Athanasiadis, Georgios, Walters, Raymond, Therrien, Karen, Nielsen, Trine Tollerup, Farajzadeh, Leila, Voloudakis, Georgios, Bendl, Jaroslav, Zeng, Biau, Zhang, Wen, Grove, Jakob, Als, Thomas D., Duan, Jinjie, Satterstrom, F. Kyle, Bybjerg-Grauholm, Jonas, Bækved-Hansen, Marie, Gudmundsson, Olafur O., Magnusson, Sigurdur H., Baldursson, Gisli, Davidsdottir, Katrin, Haraldsdottir, Gyda S., Agerbo, Esben, Hoffman, Gabriel E., Dalsgaard, Søren, Martin, Joanna, Ribasés, Marta, Boomsma, Dorret I., Soler Artigas, Maria ... iPSYCH-Broad Consortium (2023). Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics, 55 (2), 198-208. doi: 10.1038/s41588-022-01285-8

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

2023

Journal Article

Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults

Scott, Jan, Crouse, Jacob J., Medland, Sarah, Byrne, Enda, Iorfino, Frank, Mitchell, Brittany, Gillespie, Nathan A., Martin, Nicholas, Wray, Naomi and Hickie, Ian B. (2023). Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults. Early Intervention in Psychiatry, 18 (6), 397-405. doi: 10.1111/eip.13472

Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults

2022

Journal Article

Genetic diversity fuels gene discovery for tobacco and alcohol use

Saunders, Gretchen R. B., Wang, Xingyan, Chen, Fang, Jang, Seon-Kyeong, Liu, Mengzhen, Wang, Chen, Gao, Shuang, Jiang, Yu, Khunsriraksakul, Chachrit, Otto, Jacqueline M., Addison, Clifton, Akiyama, Masato, Albert, Christine M., Aliev, Fazil, Alonso, Alvaro, Arnett, Donna K., Ashley-Koch, Allison E., Ashrani, Aneel A., Barnes, Kathleen C., Barr, R. Graham, Bartz, Traci M., Becker, Diane M., Bielak, Lawrence F., Benjamin, Emelia J., Bis, Joshua C., Bjornsdottir, Gyda, Blangero, John, Bleecker, Eugene R., Boardman, Jason D. ... Vrieze, Scott (2022). Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature, 612 (7941), 720-724. doi: 10.1038/s41586-022-05477-4

Genetic diversity fuels gene discovery for tobacco and alcohol use

2022

Journal Article

Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts

Silventoinen, Karri, Piirtola, Maarit, Jelenkovic, Aline, Sund, Reijo, Tarnoki, Adam D., Tarnoki, David L., Medda, Emanuela, Nisticò, Lorenza, Toccaceli, Virgilia, Honda, Chika, Inui, Fujio, Tomizawa, Rie, Watanabe, Mikio, Sakai, Norio, Gatz, Margaret, Butler, David A., Lee, Jooyeon, Lee, Soo Ji, Sung, Joohon, Franz, Carol E., Kremen, William S., Lyons, Michael J., Derom, Catherine A., Vlietinck, Robert F., Loos, Ruth J. F., Tynelius, Per, Rasmussen, Finn, Martin, Nicholas G., Medland, Sarah E. ... Kaprio, Jaakko (2022). Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts. Scientific Reports, 12 (1) 13148, 1-9. doi: 10.1038/s41598-022-17536-x

Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts

2022

Journal Article

Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study

Gomez, Lina, Díaz-Torres, Santiago, Colodro-Conde, Lucía, Garcia-Marin, Luis M., Yap, Chloe X., Byrne, Enda M., Yengo, Loic, Lind, Penelope A., Wray, Naomi R., Medland, Sarah E., Hickie, Ian B., Lupton, Michelle K., Rentería, Miguel E., Martin, Nicholas G. and Campos, Adrian I. (2022). Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study. European Archives of Psychiatry and Clinical Neuroscience, 273 (6), 1359-1368. doi: 10.1007/s00406-022-01527-0

Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study

2022

Conference Publication

Can polygenic Risk Scores Predict Who Will Receive or Respond Better to Electroconvulsive Therapy for Treatment of Major Depressive Disorder?

Hopkins, Kristen L., Lind, Penelope A., Mitchell, Brittany L., Whiteman, David C., Olsen, Catherine M., Siskind, Dan J., Hickie, Ian B., Martin, Nicholas G. and Medland, Sarah E. (2022). Can polygenic Risk Scores Predict Who Will Receive or Respond Better to Electroconvulsive Therapy for Treatment of Major Depressive Disorder?. 51st Annual Meeting of the Behavior-Genetics-Association (BGA), Los Angeles Ca, Jun 22-25, 2022. NEW YORK: SPRINGER.

Can polygenic Risk Scores Predict Who Will Receive or Respond Better to Electroconvulsive Therapy for Treatment of Major Depressive Disorder?

2022

Conference Publication

Challenges to Incorporating Polygenic Risk Scores in Clinical Mental Health Practice

Medland, Sarah E., Mitchell, Brittany, Campos, Adrian, Whiteman, David C., Olsen, Catherine M., Siskind, Dan J., Hickie, Ian, Lind, Penelope A. and Martin, Nicholas G. (2022). Challenges to Incorporating Polygenic Risk Scores in Clinical Mental Health Practice. 51st Annual Meeting of the Behavior-Genetics-Association (BGA), Los Angeles Ca, Jun 22-25, 2022. NEW YORK: SPRINGER.

Challenges to Incorporating Polygenic Risk Scores in Clinical Mental Health Practice

2022

Journal Article

Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis

Tielbeek, Jorim J., Uffelmann, Emil, Williams, Benjamin S., Colodro-Conde, Lucía, Gagnon, Éloi, Mallard, Travis T., Levitt, Brandt E., Jansen, Philip R., Johansson, Ada, Sallis, Hannah M., Pistis, Giorgio, Saunders, Gretchen R. B., Allegrini, Andrea G., Rimfeld, Kaili, Konte, Bettina, Klein, Marieke, Hartmann, Annette M., Salvatore, Jessica E., Nolte, Ilja M., Demontis, Ditte, Malmberg, Anni L. K., Burt, S. Alexandra, Savage, Jeanne E., Sugden, Karen, Poulton, Richie, Harris, Kathleen Mullan, Vrieze, Scott, McGue, Matt, Iacono, William G. ... Spit for Science Working Group (2022). Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis. Molecular Psychiatry, 27 (11), 4453-4463. doi: 10.1038/s41380-022-01793-3

Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis

2022

Journal Article

Genetic map of regional sulcal morphology in the human brain from UK biobank data

Sun, Benjamin B., Loomis, Stephanie J., Pizzagalli, Fabrizio, Shatokhina, Natalia, Painter, Jodie N., Foley, Christopher N., Sun, Benjamin, Tsai, Ellen, Bronson, Paola, Sexton, David, John, Sally, Marshall, Eric, Patel, Mehool, Duraisamy, Saranya, Swan, Timothy, Baird, Dennis, Chen, Chia-Yen, Eaton, Susan, Gagnon, Jake, Gao, Feng, Gubbels, Cynthia, Huang, Yunfeng, Kupelian, Varant, Li, Kejie, Liu, Dawei, Loomis, Stephanie, McLaughlin, Helen, Mitchell, Adele, Jensen, Megan E. ... Biogen Biobank Team (2022). Genetic map of regional sulcal morphology in the human brain from UK biobank data. Nature Communications, 13 (1) 6071, 1-13. doi: 10.1038/s41467-022-33829-1

Genetic map of regional sulcal morphology in the human brain from UK biobank data

Availability

Honorary Professor Sarah Medland is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.

    Principal Advisor

  • Master Philosophy

    Novel efficient statistical methods for biobank-scale prediction from brain imaging

    Principal Advisor

  • Doctor Philosophy

    Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    Genetic architecture of differences in symptomatology and treatment response in major depressive disorder

    Principal Advisor

    Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería

  • Doctor Philosophy

    Genetic and environmental risk factors influencing mood disorders

    Principal Advisor

Completed supervision

Enquiries

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