Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2020
Journal Article
Comparison of genome-wide association scans for quantitative and observational measures of human hair curvature
Ho, Yvonne Y. W., Mina-Vargas, Angela, Zhu, Gu, Brims, Mark, Mcnevin, Dennis, Montgomery, Grant W., Martin, Nicholas G., Medland, Sarah E. and Painter, Jodie N. (2020). Comparison of genome-wide association scans for quantitative and observational measures of human hair curvature. Twin Research and Human Genetics, 23 (5) PII S183242742000078X, 271-277. doi: 10.1017/thg.2020.78
2020
Journal Article
Genome-wide association study identifies 48 common genetic variants associated with handedness
Cuellar-Partida, Gabriel, Tung, Joyce Y., Eriksson, Nicholas, Albrecht, Eva, Aliev, Fazil, Andreassen, Ole A., Barroso, Inês, Beckmann, Jacques S., Boks, Marco P., Boomsma, Dorret I., Boyd, Heather A., Breteler, Monique M. B., Campbell, Harry, Chasman, Daniel I., Cherkas, Lynn F., Davies, Gail, de Geus, Eco J. C., Deary, Ian J., Deloukas, Panos, Dick, Danielle M., Duffy, David L., Eriksson, Johan G., Esko, Tõnu, Feenstra, Bjarke, Geller, Frank, Gieger, Christian, Giegling, Ina, Gordon, Scott D., Han, Jiali ... Medland, Sarah E. (2020). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature Human Behaviour, 5 (1), 59-70. doi: 10.1038/s41562-020-00956-y
2020
Journal Article
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
Hofer, Edith, Roshchupkin, Gennady V., Adams, Hieab H. H., Knol, Maria J., Lin, Honghuang, Li, Shuo, Zare, Habil, Ahmad, Shahzad, Armstrong, Nicola J., Satizabal, Claudia L., Bernard, Manon, Bis, Joshua C., Gillespie, Nathan A., Luciano, Michelle, Mishra, Aniket, Scholz, Markus, Teumer, Alexander, Xia, Rui, Jian, Xueqiu, Mosley, Thomas H., Saba, Yasaman, Pirpamer, Lukas, Seiler, Stephan, Becker, James T., Carmichael, Owen, Rotter, Jerome I., Psaty, Bruce M., Lopez, Oscar L., Amin, Najaf ... Hansell, Narelle K. (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications, 11 (1) 4796, 4796. doi: 10.1038/s41467-020-18367-y
2020
Journal Article
Septic shock: a genomewide association study and polygenic risk score analysis
D'Urso, Shannon, Rajbhandari, Dorrilyn, Peach, Elizabeth, De Guzman, Erika, Li, Qiang, Medland, Sarah E., Gordon, Scott D., Martin, Nicholas G., Ligthart, Symen, Brown, Matthew A., Powell, Joseph, McArthur, Colin, Rhodes, Andrew, Meyer, Jason, Finfer, Simon, Myburgh, John, Blumenthal, Antje, Cohen, Jeremy, Venkatesh, Balasubramanian, Cuellar-Partida, Gabriel and Evans, David M. (2020). Septic shock: a genomewide association study and polygenic risk score analysis. Twin Research and Human Genetics, 23 (4) PII S1832427420000602, 204-213. doi: 10.1017/thg.2020.60
2020
Journal Article
Cohort profile: the Australian genetics of depression study
Byrne, Enda M., Kirk, Katherine M., Medland, Sarah E., McGrath, John J., Colodro-Conde, Lucia, Parker, Richard, Cross, Simone, Sullivan, Lenore, Statham, Dixie J., Levinson, Douglas F., Licinio, Julio, Wray, Naomi R, Hickie, Ian B. and Martin, Nicholas G. (2020). Cohort profile: the Australian genetics of depression study. BMJ Open, 10 (5) e032580, e032580. doi: 10.1136/bmjopen-2019-032580
2020
Journal Article
Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
Han, Laura K. M., Dinga, Richard, Hahn, Tim, Ching, Christopher R. K., Eyler, Lisa T., Aftanas, Lyubomir, Aghajani, Moji, Aleman, André, Baune, Bernhard T., Berger, Klaus, Brak, Ivan, Filho, Geraldo Busatto, Carballedo, Angela, Connolly, Colm G., Couvy-Duchesne, Baptiste, Cullen, Kathryn R., Dannlowski, Udo, Davey, Christopher G., Dima, Danai, Duran, Fabio L. S., Enneking, Verena, Filimonova, Elena, Frenzel, Stefan, Frodl, Thomas, Fu, Cynthia H. Y., Godlewska, Beata R., Gotlib, Ian H., Grabe, Hans J., Groenewold, Nynke A. ... Schmaal, Lianne (2020). Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group. Molecular Psychiatry, 26 (9), 5124-5139. doi: 10.1038/s41380-020-0754-0
2020
Journal Article
Mapping brain asymmetry in health and disease through the ENIGMA consortium
Kong, Xiang-Zhen, Postema, Merel C., Guadalupe, Tulio, de Kovel, Carolien, Boedhoe, Premika S. W., Hoogman, Martine, Mathias, Samuel R., van Rooij, Daan, Schijven, Dick, Glahn, David C., Medland, Sarah E., Jahanshad, Neda, Thomopoulos, Sophia I., Turner, Jessica A., Buitelaar, Jan, van Erp, Theo G. M., Franke, Barbara, Fisher, Simon E., van den Heuvel, Odile A., Schmaal, Lianne, Thompson, Paul M. and Francks, Clyde (2020). Mapping brain asymmetry in health and disease through the ENIGMA consortium. Human Brain Mapping, 43 (1) hbm.25033, 167-181. doi: 10.1002/hbm.25033
2020
Journal Article
Educational attainment polygenic scores are associated with cortical total surface area and regions important for language and memory
Mitchell, Brittany L., Cuéllar-Partida, Gabriel, Grasby, Katrina L., Campos, Adrian I., Strike, Lachlan T., Hwang, Liang-Dar, Okbay, Aysu, Thompson, Paul M., Medland, Sarah E., Martin, Nicholas G., Wright, Margaret J. and Rentería, Miguel E. (2020). Educational attainment polygenic scores are associated with cortical total surface area and regions important for language and memory. NeuroImage, 212 116691, 116691. doi: 10.1016/j.neuroimage.2020.116691
2020
Journal Article
Curly questions
Medland, Sarah E. (2020). Curly questions. Twin Research and Human Genetics, 23 (2), 98-99. doi: 10.1017/thg.2020.23
2020
Journal Article
Editorial
Evans, David, Medland, Sarah E. and Gillespie, Nathan (2020). Editorial. Twin Research and Human Genetics, 23 (2), 67-67. doi: 10.1017/thg.2020.45
2020
Journal Article
ENIGMA and global neuroscience: a decade of large-scale studies of the brain in health and disease across more than 40 countries
Thompson, Paul M., Jahanshad, Neda, Ching, Christopher R. K., Salminen, Lauren E., Thomopoulos, Sophia I., Bright, Joanna, Baune, Bernhard T., Bertolín, Sara, Bralten, Janita, Bruin, Willem B., Bülow, Robin, Chen, Jian, Chye, Yann, Dannlowski, Udo, de Kovel, Carolien G. F., Donohoe, Gary, Eyler, Lisa T., Faraone, Stephen V., Favre, Pauline, Filippi, Courtney A., Frodl, Thomas, Garijo, Daniel, Gil, Yolanda, Grabe, Hans J., Grasby, Katrina L., Hajek, Tomas, Han, Laura K. M., Hatton, Sean N., Hilbert, Kevin ... Zelman, Vladimir (2020). ENIGMA and global neuroscience: a decade of large-scale studies of the brain in health and disease across more than 40 countries. Translational psychiatry, 10 (1) 100, 100. doi: 10.1038/s41398-020-0705-1
2020
Journal Article
The genetic architecture of the human cerebral cortex
Grasby, Katrina L., Jahanshad, Neda, Painter, Jodie N., Colodro-Conde, Lucía, Bralten, Janita, Hibar, Derrek P., Lind, Penelope A., Pizzagalli, Fabrizio, Ching, Christopher R. K., McMahon, Mary Agnes B., Shatokhina, Natalia, Zsembik, Leo C. P., Thomopoulos, Sophia I., Zhu, Alyssa H., Strike, Lachlan T., Agartz, Ingrid, Alhusaini, Saud, Almeida, Marcio A. A., Alnæs, Dag, Amlien, Inge K., Andersson, Micael, Ard, Tyler, Armstrong, Nicola J., Ashley-Koch, Allison, Atkins, Joshua R., Bernard, Manon, Brouwer, Rachel M., Buimer, Elizabeth E. L., Bülow, Robin ... Medland, Sarah E. (2020). The genetic architecture of the human cerebral cortex. Science, 367 (6484) aay6690, 1-17. doi: 10.1126/science.aay6690
2020
Journal Article
Genome-wide association analysis in humans links nucleotide metabolism to Leukocyte Telomere Length
Li, Chen, Stoma, Svetlana, Lotta, Luca A., Warner, Sophie, Albrecht, Eva, Allione, Alessandra, Arp, Pascal P., Broer, Linda, Buxton, Jessica L., Da Silva Couto Alves, Alexessander, Deelen, Joris, Fedko, Iryna O., Gordon, Scott D., Jiang, Tao, Karlsson, Robert, Kerrison, Nicola, Loe, Taylor K., Mangino, Massimo, Milaneschi, Yuri, Miraglio, Benjamin, Pervjakova, Natalia, Russo, Alessia, Surakka, Ida, van der Spek, Ashley, Verhoeven, Josine E., Amin, Najaf, Beekman, Marian, Blakemore, Alexandra I., Canzian, Federico ... Codd, Veryan (2020). Genome-wide association analysis in humans links nucleotide metabolism to Leukocyte Telomere Length. American Journal of Human Genetics, 106 (3), 389-404. doi: 10.1016/j.ajhg.2020.02.006
2020
Journal Article
Rethinking Measurement of Parenting Stress in ADHD-Affected Families: A Principal Components Analysis of the Disruptive Behaviour Stress Inventory
Maclean, Emmalie I., Andrew, Brooke, Lind, Penelope A. and Medland, Sarah E. (2020). Rethinking Measurement of Parenting Stress in ADHD-Affected Families: A Principal Components Analysis of the Disruptive Behaviour Stress Inventory. Journal of Child and Family Studies, 29 (11), 3253-3264. doi: 10.1007/s10826-020-01799-x
2020
Journal Article
Prevalence of self-reported subthreshold phenotypes of major mental disorders and their association with functional impairment, treatment and full-threshold syndromes in a community-residing cohort of young adults
Scott, Jan, Martin, Nicholas G., Parker, Richard, Couvy-Duchesne, Baptiste, Medland, Sarah E. and Hickie, Ian (2020). Prevalence of self-reported subthreshold phenotypes of major mental disorders and their association with functional impairment, treatment and full-threshold syndromes in a community-residing cohort of young adults. Early Intervention in Psychiatry, 15 (2) eip.12942, 306-313. doi: 10.1111/eip.12942
2020
Conference Publication
Association between polygenic risk score and risk of myopia
Mojarrad, Neema Ghorbani, Plotnikov, Denis, Williams, Cathy, Guggenheim, Jeremy A., Aslam, Tariq, Barman, Sarah A., Barrett, Jenny H., Bishop, Paul, Blows, Peter, Bunce, Catey, Carare, Roxana O., Chakravarthy, Usha, Chan, Michelle, Chua, Sharon Y. L., Crabb, David P., Cumberland, Philippa M., Day, Alexander, Desai, Parul, Dhillon, Bal, Dick, Andrew D., Egan, Cathy, Ennis, Sarah, Foster, Paul, Fruttiger, Marcus, Gallacher, John E. J., Garway-Heath, David F., Gibson, Jane, Gore, Dan, Guggenheim, Jeremy A. ... Zheng, Yalin (2020). Association between polygenic risk score and risk of myopia. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Vancouver, Canada, 28 April-2 May 2019. Chicago, IL USA: American Medical Association. doi: 10.1001/jamaophthalmol.2019.4421
2020
Journal Article
Shared genetic risk between eating disorder- and substance-use-related phenotypes: evidence from genome-wide association studies
Munn-Chernoff, Melissa A., Johnson, Emma C., Chou, Yi-Ling, Coleman, Jonathan R.I., Thornton, Laura M., Walters, Raymond K., Yilmaz, Zeynep, Baker, Jessica H., Hübel, Christopher, Gordon, Scott, Medland, Sarah E., Watson, Hunna J., Gaspar, Héléna A., Bryois, Julien, Hinney, Anke, Leppä, Virpi M., Mattheisen, Manuel, Ripke, Stephan, Yao, Shuyang, Giusti-Rodríguez, Paola, Hanscombe, Ken B., Adan, Roger A.H., Alfredsson, Lars, Ando, Tetsuya, Andreassen, Ole A., Berrettini, Wade H., Boehm, Ilka, Boni, Claudette, Boraska Perica, Vesna ... Agrawal, Arpana (2020). Shared genetic risk between eating disorder- and substance-use-related phenotypes: evidence from genome-wide association studies. Addiction Biology, 26 (1) e12880, e12880. doi: 10.1111/adb.12880
2019
Journal Article
Altered cortical brain structure and increased risk for disease seen decades after perinatal exposure to maternal smoking: a study of 9000 adults in the UK Biobank
Salminen, Lauren E., Wilcox, Rand R., Zhu, Alyssa H., Riedel, Brandalyn C., Ching, Christopher R K, Rashid, Faisal, Thomopoulos, Sophia I., Saremi, Arvin, Harrison, Marc B., Ragothaman, Anjanibhargavi, Knight, Victoria, Boyle, Christina P., Medland, Sarah E., Thompson, Paul M. and Jahanshad, Neda (2019). Altered cortical brain structure and increased risk for disease seen decades after perinatal exposure to maternal smoking: a study of 9000 adults in the UK Biobank. Cerebral Cortex, 29 (12), 5217-5233. doi: 10.1093/cercor/bhz060
2019
Journal Article
Associations between polygenic risk for tobacco and alcohol use and liability to tobacco and alcohol use, and psychiatric disorders in an independent sample of 13,999 Australian adults
Chang, Lun-Hsien, Whitfield, John B., Liu, Mengzhen, Medland, Sarah E., Hickie, Ian B., Martin, Nicholas G., Verhulst, Brad, Heath, Andrew C., Madden, Pamela A., Statham, Dixie J., Gillespie, Nathan A. and GSCAN Consortium (2019). Associations between polygenic risk for tobacco and alcohol use and liability to tobacco and alcohol use, and psychiatric disorders in an independent sample of 13,999 Australian adults. Drug and Alcohol Dependence, 205 107704, 107704. doi: 10.1016/j.drugalcdep.2019.107704
2019
Journal Article
Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings
Adams, Hieab H.H., Roshchupkin, Gennady V., DeCarli, Charles, Franke, Barbara, Grabe, Hans J., Habes, Mohamad, Jahanshad, Neda, Medland, Sarah E., Niessen, Wiro, Satizabal, Claudia L., Schmidt, Reinhold, Seshadri, Sudha, Teumer, Alexander, Thompson, Paul M., Vernooij, Meike W., Wittfeld, Katharina and Ikram, M. Arfan (2019). Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11 (C), 286-290. doi: 10.1016/j.dadm.2019.02.003
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
-
Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Principal Advisor
Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
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2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
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2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
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2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
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