Honorary Professor

Sarah Medland

Email: 

Background

Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.

Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.

ORCID: 0000-0003-1382-380X

ResearcherID: C-7630-2013

Scopus Author ID: 34571085600

Email: sarah.medland@qimrberghofer.edu.au

Qualifications

2006 PhD (Psychology), University of Queensland

Dean's Award for Outstanding Research Higher Degree Thesis

2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)

Availability

Honorary Professor Sarah Medland is:
Available for supervision

Fields of research

Applied economics Psychology

Search Professor Sarah Medland’s works on UQ eSpace

541 works between 2001 and 2025
All (541) Journal Article (458) Other Outputs (1) Conference Publication (77) Book Chapter (5)

21 - 40 of 541 works

2025

Conference Publication

Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity

Du-Harpur, Xinyi, Maxwell, Jessye, Mitchell, Brittany L., Pardo, Luba M, Witkam, Willemijn C. A. M., Dand, Nick, Bartels, Meike, Betti, Michael, Boomsma, Dorret I., Dong, Xianjun, Gerring, Zachary, Finer, Sarah, Hagenbeek, Fiona A., Hottenga, Jouke Jan, Hripcsak, George, Huilaja, Laura, Hveem, Kristian, Jacobs, Benjamin, Kals, Mart, Kaufman-Cook, James, Kettunen, Johannes, Khan, Atlas, Kingo, Kulli, Kiryluk, Krzysztof, Løset, Mari, Lunter, Gerton, Lupton, Michelle, Min, Josine L., Martin, Nicholas G. ... Simpson, Michael A. (2025). Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity. 105th Annual Meeting of the British Association of Dermatologists, Glasgow, United Kingdom, 1-3 July 2025. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/bjd/ljaf085.025

Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity

2025

Journal Article

Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling

Sunny, Sharon, Cheng, Guo, Haria, Joshua, Nazari, Iman, Chauhan, Jagmohan and Ennis, Sarah (2025). Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling. Mammalian Genome, 36 (3), 914-927. doi: 10.1007/s00335-025-10140-0

Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling

2025

Journal Article

Dissecting causal relationships between cortical morphology and neuropsychiatric disorders: a bidirectional Mendelian randomization study

Lin, Bochao Danae, Li, Yunzhi, Goula, Anastasia A., Chang, Xiao, Grasby, Katrina L., Medland, Sarah, Andreassen, Ole A., Rutten, Bart P. F., Guloksuz, Sinan, van der Meer, Dennis and Luykx, Jurjen J. (2025). Dissecting causal relationships between cortical morphology and neuropsychiatric disorders: a bidirectional Mendelian randomization study. Nature Mental Health, 3 (6) 447, 613-625. doi: 10.1038/s44220-025-00397-4

Dissecting causal relationships between cortical morphology and neuropsychiatric disorders: a bidirectional Mendelian randomization study

2025

Journal Article

Genetic links between subcortical brain morphometry and suicide attempt risk in children and adults

Ceja, Zuriel, García‐Marín, Luis M., Hung, I‐Tzu, Medland, Sarah E., Edwards, Alexis C., Rentería, Miguel E. and Rabinowitz, Jill A. (2025). Genetic links between subcortical brain morphometry and suicide attempt risk in children and adults. Human Brain Mapping, 46 (7) e70220, e70220. doi: 10.1002/hbm.70220

Genetic links between subcortical brain morphometry and suicide attempt risk in children and adults

2025

Journal Article

Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI

Zhu, Alyssa H., Nir, Talia M., Javid, Shayan, Villalón-Reina, Julio E., Rodrigue, Amanda L., Strike, Lachlan T., de Zubicaray, Greig I., McMahon, Katie L., Wright, Margaret J., Medland, Sarah E., Blangero, John, Glahn, David C., Kochunov, Peter, Williamson, Douglas E., Håberg, Asta K., Thompson, Paul M. and Jahanshad, Neda (2025). Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI. Scientific Data, 12 (1) 748, 748. doi: 10.1038/s41597-025-05028-2

Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI

2025

Journal Article

Impulsivity behaviors and white matter mediate the relationship between genetic risk for cannabis use disorder and early cannabis use in adolescents

Cupertino, Renata Basso, Medland, Sarah Elizabeth, Ottino-Gonzalez, Jonatan, Cao, Zhipeng, Juliano, Anthony, Pancholi, Devarshi, Banaschewski, Tobias, Bokde, Arun L. W., Desrivières, Sylvane, Flor, Herta, Grigis, Antoine, Gowland, Penny, Heinz, Andreas, Brühl, Rüdiger, Martinot, Jean-Luc, Martinot, Marie-Laure Paillère, Artiges, Eric, Nees, Frauke, Orfanos, Dimitri Papadopoulos, Lemaitre, Herve, Paus, Tomáš, Poustka, Luise, Hohmann, Sarah, Fröhner, Juliane H., Smolka, Michael N., Walter, Henrik, Whelan, Robert, Schumann, Gunter, Conrod, Patricia ... Mackey, Scott (2025). Impulsivity behaviors and white matter mediate the relationship between genetic risk for cannabis use disorder and early cannabis use in adolescents. Addiction, 120 (5), 984-996. doi: 10.1111/add.16750

Impulsivity behaviors and white matter mediate the relationship between genetic risk for cannabis use disorder and early cannabis use in adolescents

2025

Journal Article

A genome-wide association study of brain function across multiple cognitive domains

Waller, L, Bröcker, A-L, Elbersgerd, N, Jaeck, F, Lipka, R, Mograby, L, Neidhart, M, Puzicha, R, Rahimova, F, Reinhardt, P, Reppmann, Z, Schäfer, N, Serin, E, Vaidya, N, Vogel, B, Wellan, S, Winterer, J, Göller, D, Henze, G-I, Pizzagalli, F, D'Agostino, C, Liao, Z, Paus, T, Nyberg, L, Andersson, M, Hermesdorf, M, Berger, K, Dannlowski, U, Kircher, T ... Walter, H (2025). A genome-wide association study of brain function across multiple cognitive domains. Pharmacopsychiatry, 58 (03), 147-148. doi: 10.1055/s-0045-1807310

A genome-wide association study of brain function across multiple cognitive domains

2025

Journal Article

Recent breakthroughs in genetic and brain structural correlates of suicidal behaviours: a short review

Ceja, Zuriel, Van Velzen, Laura S., Campos, Adrian I., Jahanshad, Neda, Medland, Sarah E., Edwards, Alexis C., Schmaal, Lianne and Rentería, Miguel E. (2025). Recent breakthroughs in genetic and brain structural correlates of suicidal behaviours: a short review. Biological Psychiatry, 97 (8), 775-785. doi: 10.1016/j.biopsych.2024.09.010

Recent breakthroughs in genetic and brain structural correlates of suicidal behaviours: a short review

2025

Journal Article

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

Mosley, Philip E., van der Meer, Johan N., Hamilton, Lachlan H. W., Fripp, Jurgen, Parker, Stephen, Jeganathan, Jayson, Breakspear, Michael, Parker, Richard, Holland, Rebecca, Mitchell, Brittany L., Byrne, Enda, Hickie, Ian B., Medland, Sarah E., Martin, Nicholas G. and Cocchi, Luca (2025). Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli. Molecular Psychiatry, 30 (3) 11605, 848-860. doi: 10.1038/s41380-024-02699-y

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

2025

Journal Article

Clozapine efficacy and adverse drug reactions among a nationwide study of 1021 Australians prescribed clozapine: The ClozaGene Study

Lind, Penelope A., Parker, Richard K., Northwood, Korinne, Siskind, Dan J. and Medland, Sarah E. (2025). Clozapine efficacy and adverse drug reactions among a nationwide study of 1021 Australians prescribed clozapine: The ClozaGene Study. Schizophrenia Bulletin, 51 (2) sbae065, 458-469. doi: 10.1093/schbul/sbae065

Clozapine efficacy and adverse drug reactions among a nationwide study of 1021 Australians prescribed clozapine: The ClozaGene Study

2025

Journal Article

Polygenic risk scores and help-seeking behaviour in young people with recent onset of mood and psychotic disorders

Scott, Jan, Crouse, Jacob J., Medland, Sarah E., Mitchell, Brittany L., Gillespie, Nathan A., Martin, Nicholas G. and Hickie, Ian B. (2025). Polygenic risk scores and help-seeking behaviour in young people with recent onset of mood and psychotic disorders. Journal of Affective Disorders, 372, 40-47. doi: 10.1016/j.jad.2024.11.067

Polygenic risk scores and help-seeking behaviour in young people with recent onset of mood and psychotic disorders

2025

Journal Article

Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression

Crouse, Jacob J., Park, Shin Ho, Mitchell, Brittany L., Byrne, Enda M., Medland, Sarah E., Lin, Tian, Scott, Jan, de Haan, Zsofi, Tonini, Emiliana, Iorfino, Frank, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2025). Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression. European Psychiatry, 68 (1) e41, 1-9. doi: 10.1192/j.eurpsy.2025.20

Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression

2025

Journal Article

Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses

Panagiotaropoulou, Georgia, Hellberg, Kajsa-Lotta Georgii, Coleman, Jonathan R. I., Seok, Darsol, Kalman, Janos, Mitchell, Philip B., Schofield, Peter R., Forstner, Andreas J., Bauer, Michael, Scott, Laura J., Pato, Carlos N., Pato, Michele T., Li, Qingqin S., Kirov, George, Landén, Mikael, Jonsson, Lina, Müller-Myhsok, Bertram, Smoller, Jordan W., Binder, Elisabeth B., Brückl, Tanja M., Czamara, Darina, Van Der Auwera, Sandra, Grabe, Hans J., Homuth, Georg, Schmidt, Carsten O., Potash, James B., Depaulo, J. Raymond, Goes, Fernando S., Mackinnon, Dean F. ... Olde Loohuis, Loes (2025). Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses. British Journal of Psychiatry, 226 (2), 1-12. doi: 10.1192/bjp.2024.125

Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses

2025

Journal Article

Genomics yields biological and phenotypic insights into bipolar disorder

O’Connell, Kevin S., Koromina, Maria, van der Veen, Tracey, Boltz, Toni, David, Friederike S., Yang, Jessica Mei Kay, Lin, Keng-Han, Wang, Xin, Coleman, Jonathan R. I., Mitchell, Brittany L., McGrouther, Caroline C., Rangan, Aaditya V., Lind, Penelope A., Koch, Elise, Harder, Arvid, Parker, Nadine, Bendl, Jaroslav, Adorjan, Kristina, Agerbo, Esben, Albani, Diego, Alemany, Silvia, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F. M., Antoniou, Anastasia, Ask, Helga, Bass, Nicholas, Bauer, Michael, Beins, Eva C. ... Andreassen, Ole A. (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639 (8056), 968-975. doi: 10.1038/s41586-024-08468-9

Genomics yields biological and phenotypic insights into bipolar disorder

2025

Journal Article

Investigating the Relationship Between Maternal Smoking During Pregnancy and Offspring Handedness: Extending the Proxy Gene-by-Environment Mendelian Randomization Study Design to Include Polygenic Risk Scores

Crick, Daisy C. P., Medland, Sarah E., Smith, George Davey and Evans, David M. (2025). Investigating the Relationship Between Maternal Smoking During Pregnancy and Offspring Handedness: Extending the Proxy Gene-by-Environment Mendelian Randomization Study Design to Include Polygenic Risk Scores. Behavior Genetics, 55 (4), 1-13. doi: 10.1007/s10519-025-10226-0

Investigating the Relationship Between Maternal Smoking During Pregnancy and Offspring Handedness: Extending the Proxy Gene-by-Environment Mendelian Randomization Study Design to Include Polygenic Risk Scores

2024

Conference Publication

A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner

Boltz, Toni, Chu, Benjamin, Sealock, Julia, Liao, Calwing, Zhan, Lingyu, Fu, Jack, Ye, Robert, Majara, Lerato, Chapman, Sinead, DeFelice, Matthew, Grimsby, Jonna, Rubinacci, Simone, Akena, Dickens, Atkinson, Elizabeth, Atwoli, Lukoye, Bigdeli, Tim, Freimer, Nelson, Gatzen, Michael, Huang, Hailiang, Kachulis, Christopher, Kariuki, Symon, Kim, Soyeon, Koenen, Karestan, Jaramillo, Carlos Lopez, McMahon, Justin, Medland, Sarah, Newton, Charles, Veira, Ana Maria Olivares, Pato, Carlos ... Martin, Alicia (2024). A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner. 57th Conference of the European-Society-of-Human-Genetics (ESHG), Berlin Germany, Jun 01-04, 2024. LONDON: SPRINGERNATURE.

A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner

2024

Conference Publication

Harnessing RNA-Sequencing in rare disease diagnostics: Insights from a multi-regional pilot project

Oquendo, Carolina Jaramillo, Lyon, Matthew, Bunyan, Dave, Abbott, Jacob, Woodley, Jessica, Court, Samantha, Bell, Jennie, Douglas, Andrew, Willis, Sarah, Thomas, N. Simon, Williams, Anthony, Ennis, Sarah and Baralle, Diana (2024). Harnessing RNA-Sequencing in rare disease diagnostics: Insights from a multi-regional pilot project. LONDON: SPRINGERNATURE.

Harnessing RNA-Sequencing in rare disease diagnostics: Insights from a multi-regional pilot project

2024

Journal Article

Accelerating heritability, genetic correlation, and genome‐wide association imaging genetic analyses in complex pedigrees

Donohue, Brian, Gao, Si, Nichols, Thomas E., Adhikari, Bhim M., Ma, Yizhou, Jahanshad, Neda, Thompson, Paul M., McMahon, Francis J., Humphries, Elizabeth M., Burroughs, William, Ament, Seth A., Mitchell, Braxton D., Ma, Tianzhou, Chen, Shuo, Medland, Sarah E., Blangero, John, Hong, L. Elliot and Kochunov, Peter (2024). Accelerating heritability, genetic correlation, and genome‐wide association imaging genetic analyses in complex pedigrees. Human Brain Mapping, 45 (17) e70044, 1-15. doi: 10.1002/hbm.70044

Accelerating heritability, genetic correlation, and genome‐wide association imaging genetic analyses in complex pedigrees

2024

Journal Article

The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety

Monistrol-Mula, Anna, Felez-Nobrega, Mireia, Byrne, Enda M., Lind, Penelope A., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Colodro-Conde, Lucía and Mitchell, Brittany L. (2024). The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety. Psychological Medicine, 54 (15), 4140-4149. doi: 10.1017/s0033291724001983

The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety

2024

Conference Publication

Shared Genetic Liability Between Nausea and Vomiting During Pregnancy and Mental Health Disorders

Painter, Jodie N., Grasby, Katrina G., Lind, Penelope A., Colodro-Conde, Lucia and Medland, Sarah E. (2024). Shared Genetic Liability Between Nausea and Vomiting During Pregnancy and Mental Health Disorders. 54th Annual Meeting of the Behavior-Genetics-Association (BGA), London England, Jun 26-29, 2024. NEW YORK: SPRINGER.

Shared Genetic Liability Between Nausea and Vomiting During Pregnancy and Mental Health Disorders

Availability

Honorary Professor Sarah Medland is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.

    Principal Advisor

  • Master Philosophy

    Novel efficient statistical methods for biobank-scale prediction from brain imaging

    Principal Advisor

  • Doctor Philosophy

    Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    Genetic and environmental risk factors influencing mood disorders

    Principal Advisor

  • Doctor Philosophy

    Genetic architecture of differences in symptomatology and treatment response in major depressive disorder

    Associate Advisor

    Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería

Completed supervision

Enquiries

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