Overview
Background
Prof Siskind trained as a psychiatrist in Australia and the United States. He graduated from medicine at the University of Queensland in 1998. After working with Doctors Without Borders in Chechnya in 2000, he became interested in psychiatry. He moved to Boston in 2002, where he did his psychiatry residency at Boston University and a Master of Public Health at Harvard University. He returned to Brisbane in June 2008 as a clinical academic psychiatrist at the Metro South Addiction and Mental Health Service. He completed his Ph.D in Feb 2014. His research interests include clozapine and treatment refractory schizophrenia, the physical health of people with severe and persistent mental illness, supported accommodation, assertive community treatment and mental health services research. He was awarded an NHMRC Investigator Grant as a Leadership Fellow (L1 2027-2031) an Emerging Leadership Fellow (EL2 2021-2025) and an NHMRC Early Career Fellowship (ECF 2016-2019). He has a current CIA MRFF RCRDUN grant looking at treatments to reduce cardiometabolic morbidity among people with schizophrenia. He was the SIRS 2026 Outstanding Clinical and Community Research Award recipient, and was elected to the Australian Academy of Health and Medical Sciences in 2025. He has over 350 peer reviewed publications, including first author in the highly ranked Lancet, World Psychiatry, Lancet Psychiatry, BJPsych, ANZJP, & Schizophrenia Bulletin. He is a named investigator on over $65 million in competitive research grants, with over $9 million as CIA.
Availability
- Professor Dan Siskind is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Schizophrenia
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Physical Health Comorbidity
Research impacts
Prof Siskind's research has had direct, measurable impact on clinical practice and policy. His landmark studies on clozapine-associated neutropenia demonstrated that routine monitoring could safely cease after two years, evidence that has driven the removal of long-term monitoring mandates by regulators — improving safe and quality access to clozapine for more than 2.5 million people globally. His work establishing optimal plasma clozapine reference ranges is now used by pathology providers across Australia, while his findings on antipsychotic-associated metabolic risk and weight gain have been incorporated into international guidelines and adopted into clinical practice, with metformin augmentation now regularly prescribed for patients commencing antipsychotics. His Lancet Psychiatry Commission on physical health in people with mental illness helped set the global agenda for integrating physical and mental healthcare, informing policy from the WHO, OECD, and across multiple countries. As Chair of the INTEGRATE Steering Committee, he led development of the first consensus-based, algorithmic international guidelines for schizophrenia treatment, which have been endorsed by peak bodies. Through sustained engagement with regulators, professional colleges and health services, Prof Siskind has ensured his research translates rapidly from bench to bedside to policy, cementing his reputation as a global leader in schizophrenia care.
Works
Search Professor Dan Siskind’s works on UQ eSpace
2017
Conference Publication
Schizophrenia and physical health - a whole body experience
Hahn, L., Kisely, S., Suetani, S., Lappin, Julia and Siskind, D. (2017). Schizophrenia and physical health - a whole body experience. LONDON: SAGE PUBLICATIONS LTD. doi: 10.1177/0004867417702054
2017
Conference Publication
Are collaborations the key to successful public sector research?
Galletly, C., Sujeeve, S., Liu, D., Schubert, O. and Siskind, D. (2017). Are collaborations the key to successful public sector research?. RANZCP 2017 Congress, Adelaide, Australia, 30 April - 4 May 2017. London, United Kingdom: Sage Publications.
2017
Conference Publication
Clozapine and ECT for treatment-refractory schizophrenia
Siskind, D. (2017). Clozapine and ECT for treatment-refractory schizophrenia. RANZCP 2017 Congress, Adelaide, Australia, 30 April - 4 May 2017. London, United Kingdom: Sage Publications.
2017
Conference Publication
Evaluating Effects of a Physical Activity Intervention Implemented At a Residential Mental Health Rehabilitation Unit
Korman, N., Siskind, D., Shah, S., Dark, F., Kendall, K. and Nadareishvili, K. (2017). Evaluating Effects of a Physical Activity Intervention Implemented At a Residential Mental Health Rehabilitation Unit. RANZCP 2017 Congress, Adelaide, Australia, 30 April - 4 May 2017. London, United Kingdom: Sage Publications.
2017
Conference Publication
Integrating psychiatric rehabilitation into clinical practice
Killaspy, H., Harvey, C., Dark, F. and Siskind, D. (2017). Integrating psychiatric rehabilitation into clinical practice. RANZCP 2017 Congress, Adelaide, Australia, 30 April - 4 May 2017. London, United Kingdom: Sage Publications.
2016
Journal Article
Fever, confusion, acute kidney injury: is this atypical neuroleptic malignant syndrome following polypharmacy with clozapine and risperidone?
Cherry, Scott, Siskind, Dan, Spivak, Valeria, Wysoczanski, Daniel and Halangoda, Priyangika (2016). Fever, confusion, acute kidney injury: is this atypical neuroleptic malignant syndrome following polypharmacy with clozapine and risperidone?. Australasian Psychiatry, 24 (6), 602-603. doi: 10.1177/1039856216649768
2016
Journal Article
Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis
Siskind, Dan, McCartney, Lara, Goldschlager, Romi and Kisely, Steve (2016). Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis. British Journal of Psychiatry, 209 (5), 385-392. doi: 10.1192/bjp.bp.115.177261
2016
Journal Article
An evidence-based scale for the antecedents of depressive symptoms in Australian adults
Liu, Xin, Furuya-Kanamori, Luis, Siskind, Dan, Crompton, David, Williams, Gail M., Kostner, Karam, Vitetta, Luis and Doi, Suhail A. (2016). An evidence-based scale for the antecedents of depressive symptoms in Australian adults. Australasian Psychiatry, 24 (5), 466-469. doi: 10.1177/1039856216629842
2016
Journal Article
N-acetylcysteine (NAC) in schizophrenia resistant to clozapine: a double blind randomised placebo controlled trial targeting negative symptoms
Rossell, Susan L., Francis, Paul S., Galletly, Cherrie, Harris, Anthony, Siskind, Dan, Berk, Michael, Bozaoglu, Kiymet, Dark, Frances, Dean, Olivia, Liu, Dennis, Meyer, Denny, Neill, Erica, Phillipou, Andrea, Sarris, Jerome and Castle, David J. (2016). N-acetylcysteine (NAC) in schizophrenia resistant to clozapine: a double blind randomised placebo controlled trial targeting negative symptoms. BMC Psychiatry, 16 (1) 320, 320. doi: 10.1186/s12888-016-1030-3
2016
Journal Article
Metabolic monitoring and management among clozapine users
Tso, Grace, Kumar, Puja, Jayasooriya, Thilini, Kisely, Steve and Siskind, Dan (2016). Metabolic monitoring and management among clozapine users. Australasian Psychiatry, 25 (1), 48-52. doi: 10.1177/1039856216665282
2016
Journal Article
Successful rechallenge with clozapine after treatment associated eosinophilia
McArdle, Peter A., Siskind, Dan J., Kolur, Uday, Parker, Stephen, Korman, Nicole and Purushothaman, Subramanian (2016). Successful rechallenge with clozapine after treatment associated eosinophilia. Australasian Psychiatry, 24 (4), 365-367. doi: 10.1177/1039856216654399
2016
Journal Article
The oral health of people with anxiety and depressive disorders - A systematic review and meta-analysis
Kisely, Steve, Sawyer, Emily, Siskind, Dan and Lalloo, Ratilal (2016). The oral health of people with anxiety and depressive disorders - A systematic review and meta-analysis. Journal of Affective Disorders, 200, 119-132. doi: 10.1016/j.jad.2016.04.040
2016
Journal Article
Clozapine users in Australia: their characteristics and experiences of care based on data from the 2010 National Survey of High Impact Psychosis
Siskind, D. J., Harris, M., Phillipou, A., Morgan, V. A., Waterreus, A., Galletly, C., Carr, V. J., Harvey, C. and Castle, D. (2016). Clozapine users in Australia: their characteristics and experiences of care based on data from the 2010 National Survey of High Impact Psychosis. Epidemiology and Psychiatric Sciences, 26 (3), 1-13. doi: 10.1017/S2045796016000305
2016
Journal Article
Weight loss associated with exenatide in an obese man with diabetes commenced on clozapine
Siskind, Dan, Wysoczanski, Daniel, Russell, Anthony and Ashford, Mark (2016). Weight loss associated with exenatide in an obese man with diabetes commenced on clozapine. Australian and New Zealand Journal of Psychiatry, 50 (7), 702-703. doi: 10.1177/0004867416636243
2016
Journal Article
Metformin for clozapine associated obesity: a systematic review and meta-analysis
Siskind, Dan J., Leung, Janni, Russell, Anthony W., Wysoczanski, Daniel and Kisely, Steve (2016). Metformin for clozapine associated obesity: a systematic review and meta-analysis. PLoS ONE, 11 (6) e0156208, e0156208. doi: 10.1371/journal.pone.0156208
2016
Journal Article
Longitudinal comparative evaluation of the equivalence of an integrated peer-support and clinical staffing model for residential mental health rehabilitation: a mixed methods protocol incorporating multiple stakeholder perspectives
Parker, Stephen, Dark, Frances, Newman, Ellie, Korman, Nicole, Meurk, Carla, Siskind, Dan and Harris, Meredith (2016). Longitudinal comparative evaluation of the equivalence of an integrated peer-support and clinical staffing model for residential mental health rehabilitation: a mixed methods protocol incorporating multiple stakeholder perspectives. BMC Psychiatry, 16 (1) 179, 179. doi: 10.1186/s12888-016-0882-x
2016
Journal Article
People living with psychosocial disability: rehabilitation and recovery-informed service provision within the second Australian national survey of psychosis
Harvey, Carol, Brophy, Lisa, Parsons, Samuel, Moeller-Saxone, Kristen, Grigg, Margaret and Siskind, Dan (2016). People living with psychosocial disability: rehabilitation and recovery-informed service provision within the second Australian national survey of psychosis. Australian and New Zealand Journal of Psychiatry, 50 (6), 534-547. doi: 10.1177/0004867415610437
2016
Conference Publication
An Introduction to Conducting Research in Clinical Settings
Siskind, D., Parker, S. and Kisely, S. (2016). An Introduction to Conducting Research in Clinical Settings. LONDON: SAGE PUBLICATIONS LTD.
2016
Conference Publication
How to Write a Research Question
Siskind, D. (2016). How to Write a Research Question.
2016
Journal Article
The mental health of older persons after human-induced disasters: A systematic review and meta-analysis of epidemiological data
Siskind, Dan J, Sawyer, Emily, Lee, Irene, Lie, David C., Martin-Khan, Melinda, Farrington, Julia, Crompton, David and Kisely, Steve (2016). The mental health of older persons after human-induced disasters: A systematic review and meta-analysis of epidemiological data. American Journal of Geriatric Psychiatry, 24 (5), 379-388. doi: 10.1016/j.jagp.2015.12.010
Funding
Current funding
Supervision
Availability
- Professor Dan Siskind is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Manifestations, impacts, and clinical implications of physical multimorbidity in people living with severe mental illness
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Steve Kisely
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Doctor Philosophy
Food and nutrition security in individuals with severe mental illness
Principal Advisor
Other advisors: Dr Urska Arnautovska
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Doctor Philosophy
Measuring cognitive flexibility in rodents
Associate Advisor
Other advisors: Professor Thomas Burne
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Doctor Philosophy
Management of myocarditis among people with schizophrenia commencing clozapine
Associate Advisor
Other advisors: Associate Professor Nicola Warren
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Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Associate Advisor
Other advisors: Honorary Professor Sarah Medland
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Master Philosophy
A quantitative and qualitative study of forensic orders in Queensland
Associate Advisor
Other advisors: Professor Steve Kisely, Dr Claudia Bull
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Doctor Philosophy
Smoking Cessation in People with a Serious Mental Illness
Associate Advisor
Other advisors: Professor Steve Kisely, Professor Coral Gartner
Completed supervision
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2026
Doctor Philosophy
The Quality and Safe Use of Clozapine
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Michael Barras, Professor Steve Kisely
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2025
Doctor Philosophy
Investigating clozapine rechallenge using granulocyte-colony stimulating factor in people previously experiencing clozapine-associated neutropenia.
Principal Advisor
Other advisors: Professor Steve Kisely
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2021
Doctor Philosophy
Psychiatric clinical decision making in anti-NMDA receptor encephalitis
Principal Advisor
Other advisors: Associate Professor Stefan Blum, Professor Steve Kisely
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2024
Doctor Philosophy
The Role of the Gut Microbiome in Psychiatric Illness: From Prenatal Risk Factors to Treatment Resistance
Associate Advisor
Other advisors: Honorary Professor Jake Gratten, Honorary Professor Darryl Eyles
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2023
Doctor Philosophy
Measuring and improving cognition in a rodent model relevant to schizophrenia
Associate Advisor
Other advisors: Dr James Kesby, Professor Thomas Burne
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2022
Doctor Philosophy
Nose-to-Brain Delivery of Clozapine in Sol-Gel Systems
Associate Advisor
Other advisors: Associate Professor Harendra Parekh, Dr Preeti Pandey, Dr James Robert Falconer
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2020
Doctor Philosophy
Exploring the characteristics and service needs of carers for adults with mental illness to inform mental health service planning
Associate Advisor
Other advisors: Associate Professor Meredith Harris
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2020
Doctor Philosophy
Who receives what, from whom, and to what effect at clinically operated, community-based residential mental health rehabilitation for Severe and Persistent Mental Illness in Australia?
Associate Advisor
Other advisors: Associate Professor Meredith Harris
Media
Enquiries
Contact Professor Dan Siskind directly for media enquiries about:
- Cardiometabolic co-morbidity of schizophrenia
- Treatment Refractory Schizophrenia
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