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Associate Professor Stefan Blum
Associate Professor

Stefan Blum

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Overview

Background

Stefan is a Staff Specialist in Neurology at the Princess Alexandra Hospital (PAH) and the Mater Centre for Neuroscience. He finished his training as neurologist in 2012.

He runs dedicated multiple sclerosis (MS) and Neuroimmunology clinics at the PAH, leading in modern MS therapies. Moreover, he has been at the forefront of advancing the field of neuroimmunology in Queensland, with establishment of dedicated neuroimmunology outpatient clinics at the RBWH and PAH, combining expertise from neurologists and immunologists in the care of this very complex group of disorders.

In addition to his busy, full-time clinical workload, Stefan has been involved as PI or CI in a range of clinical trials in the fields of MS, botulinum toxin, CIDP and Pompe’s disease. Additionally, he has performed and is involved in ongoing research projects of neuroimmunological disorders such as neuromyelitis optica, myasthenia gravis and autoimmune limbic encephalitis. He has been a member of the New Horizons study to assess prevalence of anti-neuronal antibodies in patients with new onset psychosis.

Prior to this, Stefan finished a PhD in the field of ‘Immunogenetics of Guillain-Barre Syndrome and Chronic inflammatory polyneuropathy’ at the University of Queensland in 2014. He also completed a doctoral thesis at the University of Heidelberg, Germany in 2002 in the field of T cell immunology. During this time, he has developed solid skills in bench-side immunological research.

Currently, he is neurological lead in a diverse group of clinicians and scientists investigating the role of antineuronal antibodies in neurological and psychiatric disease. He supervises 3 PhD students in the field of advanced imaging in autoimmune encephalitis and multiple sclerosis. He is currently building up a laboratory to test antineuronal antibodies using live cell assays.

Availability

Associate Professor Stefan Blum is:
Available for supervision

Research interests

  • Neuronal cell surface antibodies in neurological and psychiatric disease

  • Social cognition in Multiple Sclerosis

  • The role of low dose Rituximab in autoimmune neurological disease

Research impacts

Stefan has been medical advisor and organiser of conferences of the national myasthenia gravis association. He is neurological advisor of the state-wide blood product services regarding use of immunoglobulins in neuroimmunological disorders. He is involved in the organisation of the International Society of Neuroimmunology Conference in Brisbane 2018. He is secretary of Neuroimmunology Australia, a national group of clinicians and researchers in the field of neuroimmunology. He was lead clinician in the development of referral guidelines for state-wide referral guidelines to Queensland Health Neurology services (CPC). He has been involved for many years in the education of medical student and young doctors, winning several teaching awards.

Works

Search Professor Stefan Blum’s works on UQ eSpace

90 works between 2000 and 2024

1 - 20 of 90 works

2024

Journal Article

The clinical relevance of MOG antibody testing in cerebrospinal fluid

Reynolds, Molly, Tan, Irene, Nguyen, Kristy, Merheb, Vera, Lee, Fiona X. Z., Trewin, Benjamin P, Lerch, Magdalena, Shah, Snehal, Wolfe, Nigel, Buzzard, Katherine, Lechner-Scott, Jeannette, Fabis-Pedrini, Marzena, Fok, Anthony, John, Nevin, Kneebone, Chris, Yiannikas, Con, Brown, David A., Kermode, Allan G., Reddel, Stephen, Dale, Russell C., Brilot, Fabienne, Ramanathan, Sudarshini, Adam, Robert, Andersen, Jane, Andrews, Ian, Antony, Jayne, Aouad, Patrick, Badve, Monica, Barnett, Michael H. ... on behalf of the Australasian MOGAD Study Group (2024). The clinical relevance of MOG antibody testing in cerebrospinal fluid. Annals of Clinical and Translational Neurology, 11 (9), 1-6. doi: 10.1002/acn3.52163

The clinical relevance of MOG antibody testing in cerebrospinal fluid

2024

Journal Article

Long-term efficacy and safety of Rituximab in the treatment of neuromyelitis optica spectrum disorder

Hayes, Michael Thomas Gerard, Adam, Robert J., McCombe, Pamela Ann, Walsh, Michael and Blum, Stefan (2024). Long-term efficacy and safety of Rituximab in the treatment of neuromyelitis optica spectrum disorder. Multiple Sclerosis Journal, 10 (2) ARTN 20552173241257876, 20552173241257876. doi: 10.1177/20552173241257876

Long-term efficacy and safety of Rituximab in the treatment of neuromyelitis optica spectrum disorder

2024

Journal Article

Onboarding of siponimod in secondary progressive multiple sclerosis patients in Australia: Novel, real-world evidence from the MSGo digital support programme

Hardy, TA, Aouad, P, Barnett, MH, Blum, S, Broadley, S, Carroll, WM, Crimmins, D, Griffiths, D, Hodgkinson, S, Lechner-Scott, J, Lee, A, Malhotra, R, McCombe, P, Parratt, J, Plummer, C, Van der Walt, A, Martel, K and Walker, RA (2024). Onboarding of siponimod in secondary progressive multiple sclerosis patients in Australia: Novel, real-world evidence from the MSGo digital support programme. Multiple Sclerosis Journal - Experimental, Translational and Clinical, 10 (1) ARTN 20552173231226106, 20552173231226106. doi: 10.1177/20552173231226106

Onboarding of siponimod in secondary progressive multiple sclerosis patients in Australia: Novel, real-world evidence from the MSGo digital support programme

2023

Journal Article

Phenotypic variability within the desminopathies: A case series of three patients

Yeow, Dennis, Katz, Matthew, Henderson, Robert, Prasad, Sandhir, Denman, Russell, Blum, Stefan, Davis, Mark, Robertson, Thomas and McCombe, Pamela (2023). Phenotypic variability within the desminopathies: A case series of three patients. Frontiers in Neurology, 13 1110934. doi: 10.3389/fneur.2022.1110934

Phenotypic variability within the desminopathies: A case series of three patients

2022

Journal Article

Neuroimaging characteristics may aid in diagnosis, subtyping, and prognosis in autoimmune encephalitis

Broadley, James, Wesselingh, Robb, Beech, Paul, Seneviratne, Udaya, Kyndt, Chris, Buzzard, Katherine, Nesbitt, Cassie, D’Souza, Wendyl, Brodtmann, Amy, Macdonell, Richard, Kalincik, Tomas, O’Brien, Terence J., Butzkueven, Helmut, Monif, Mastura, Griffiths, Sarah, Rushen, Tiffany, Tan, Tracie, Malpas, Charles, Halliday, Amy, Alpitsis, Rubina, Seery, Nabil, Tarlinton, David, Reddel, Steve, Hardy, Todd, Taylor, Bruce, Long, Brian, Wijeratne, Tissa, White, Owen, Fielding, Jo ... Clough, Meaghan (2022). Neuroimaging characteristics may aid in diagnosis, subtyping, and prognosis in autoimmune encephalitis. Neurological Sciences, 44 (4), 1327-1340. doi: 10.1007/s10072-022-06523-9

Neuroimaging characteristics may aid in diagnosis, subtyping, and prognosis in autoimmune encephalitis

2022

Journal Article

Oral health‐related quality of life is more strongly correlated with mental health than with oral health in relapsing‐remitting multiple sclerosis

Nangle, Matthew R., Manchery, Nithin, Swayne, Andrew, Boocock, Helen, Blum, Stefan and Henry, Julie D. (2022). Oral health‐related quality of life is more strongly correlated with mental health than with oral health in relapsing‐remitting multiple sclerosis. Journal of Oral Rehabilitation, 50 (1), 62-68. doi: 10.1111/joor.13387

Oral health‐related quality of life is more strongly correlated with mental health than with oral health in relapsing‐remitting multiple sclerosis

2022

Journal Article

Psychiatric manifestations of autoimmune encephalitis

Ford, Hannah, Griffith, Sarah, Warren, Nicola, Swayne, Adrew, Blum, Stefan, Butzkueven, Helmut, O'Brien, Terence J., Velakoulis, Dennis, Kulkarni, Jayashri and Monif, Mastura (2022). Psychiatric manifestations of autoimmune encephalitis. Autoimmunity Reviews, 21 (9) 103145, 1-7. doi: 10.1016/j.autrev.2022.103145

Psychiatric manifestations of autoimmune encephalitis

2022

Conference Publication

Novel generation of real-world evidence through MSGo, a digital support program supporting the use of siponimod in secondary progressive multiple sclerosis patients in Australia

Hardy, Todd, Aouad, Patrick, Blum, Stefan, Broadley, Simon, Carroll, William, Crimmins, Denis, Griffiths, Dayna, Hodgkinson, Suzanne, Lechner-Scott, Jeanette, Lee, Andrew, Malhotra, Ram, Parratt, John, Plummer, Chris, Walt, Anneke Van der and Walker, Robert (2022). Novel generation of real-world evidence through MSGo, a digital support program supporting the use of siponimod in secondary progressive multiple sclerosis patients in Australia. ANZAN Annual Scientific Meeting 2022, Melbourne, VIC Australia, 10-13 May 2022. London, United Kingdom: BMJ Group. doi: 10.1136/bmjno-2022-anzan.64

Novel generation of real-world evidence through MSGo, a digital support program supporting the use of siponimod in secondary progressive multiple sclerosis patients in Australia

2022

Journal Article

Treatment satisfaction in patients with relapsing-remitting multiple sclerosis initiated on teriflunomide in routine clinical practice: Australian observational data

Hardy, Todd A., Parratt, John, Beadnall, Heidi, Blum, Stefan, Macdonell, Richard, Beran, Roy G, Shuey, Neil, Lee, Andrew, Carroll, William, Shaw, Cameron, Worrell, Richard, Moody, Jana, Sedhom, Mamdouh, Barnett, Michael and Vucic, Steve (2022). Treatment satisfaction in patients with relapsing-remitting multiple sclerosis initiated on teriflunomide in routine clinical practice: Australian observational data. BMJ Neurology Open, 4 (2) e000315, 1-9. doi: 10.1136/bmjno-2022-000315

Treatment satisfaction in patients with relapsing-remitting multiple sclerosis initiated on teriflunomide in routine clinical practice: Australian observational data

2022

Journal Article

Analysing triggers for anti‐NMDA‐receptor encephalitis including herpes simplex virus encephalitis and ovarian teratoma: results from the Queensland autoimmune encephalitis cohort

Swayne, Andrew, Warren, Nicola, Prain, Kerri, Gillis, David, Wong, Richard and Blum, Stefan (2022). Analysing triggers for anti‐NMDA‐receptor encephalitis including herpes simplex virus encephalitis and ovarian teratoma: results from the Queensland autoimmune encephalitis cohort. Internal Medicine Journal, 52 (11), 1943-1949. doi: 10.1111/imj.15472

Analysing triggers for anti‐NMDA‐receptor encephalitis including herpes simplex virus encephalitis and ovarian teratoma: results from the Queensland autoimmune encephalitis cohort

2022

Journal Article

Anti-glutamic acid decarboxylase antibody screening in first-episode psychosis

Warren, Nicola, Freier, Karen, Siskind, Dan, O’Gorman, Cullen, Blum, Stefan, Gillis, David and Scott, James G (2022). Anti-glutamic acid decarboxylase antibody screening in first-episode psychosis. Australian and New Zealand Journal of Psychiatry, 57 (4) ARTN 00048674221089560, 48674221089560-612. doi: 10.1177/00048674221089560

Anti-glutamic acid decarboxylase antibody screening in first-episode psychosis

2022

Journal Article

Episodic foresight in multiple sclerosis

Manchery, Nithin, Henry, Julie D., Blum, Stefan, Swayne, Andrew, Beer, Reuben, Rendell, Peter G. and Nangle, Matthew R. (2022). Episodic foresight in multiple sclerosis. Neuropsychology, 36 (2), 140-149. doi: 10.1037/neu0000785

Episodic foresight in multiple sclerosis

2021

Journal Article

Cognitive function and oral health in relapsing–remitting multiple sclerosis

Manchery, Nithin, Henry, Julie D., Swayne, Andrew, Beer, Reuben, Blum, Stefan and Nangle, Matthew R. (2021). Cognitive function and oral health in relapsing–remitting multiple sclerosis. Clinical Oral Investigations, 26 (3), 2899-2907. doi: 10.1007/s00784-021-04272-1

Cognitive function and oral health in relapsing–remitting multiple sclerosis

2021

Journal Article

MRI patterns distinguish AQP4 antibody positive neuromyelitis optica spectrum disorder from multiple sclerosis

Clarke, Laura, Arnett, Simon, Bukhari, Wajih, Khalilidehkordi, Elham, Jimenez Sanchez, Sofia, O'Gorman, Cullen, Sun, Jing, Prain, Kerri M., Woodhall, Mark, Silvestrini, Roger, Bundell, Christine S., Abernethy, David A., Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brownlee, Wallace, Butzkueven, Helmut, Carroll, William M., Chen, Cella, Coulthard, Alan, Dale, Russell C., Das, Chandi, Fabis-Pedrini, Marzena J., Gillis, David, Hawke, Simon, Heard, Robert, Henderson, Andrew P. D. ... Broadley, Simon A. (2021). MRI patterns distinguish AQP4 antibody positive neuromyelitis optica spectrum disorder from multiple sclerosis. Frontiers in Neurology, 12 722237, 722237. doi: 10.3389/fneur.2021.722237

MRI patterns distinguish AQP4 antibody positive neuromyelitis optica spectrum disorder from multiple sclerosis

2021

Journal Article

NMOSD and MS prevalence in the Indigenous populations of Australia and New Zealand

Bukhari, Wajih, Khalilidehkordi, Elham, Mason, Deborah F., Barnett, Michael H., Taylor, Bruce V., Fabis-Pedrini, Marzena, Kermode, Allan G., Subramanian, Sankar, Waters, Patrick, Broadley, Simon A., Bukhari, Wajih, Broadley, Simon A., Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brilot, Fabienne, Brownlee, Wallace J., Bundell, Christine S., Butzkueven, Helmut, Carroll, William M., Chen, Celia, Clarke, Laura, Coulthard, Alan, Dale, Russell C., Das, Chandi, Dear, Keith ... Yiu, Eppie M. (2021). NMOSD and MS prevalence in the Indigenous populations of Australia and New Zealand. Journal of Neurology, 269 (2), 836-845. doi: 10.1007/s00415-021-10665-9

NMOSD and MS prevalence in the Indigenous populations of Australia and New Zealand

2021

Conference Publication

Case Series: Two Cases of First Presentation AQP4-IgG Antibody Positive Neuromyelitis Optica in Patients of Advanced Age as a Possible Paraneoplastic Phenomenon

Beer, Reuben, Shahid, Hassan, Brown, Helen and Blum, Stefan (2021). Case Series: Two Cases of First Presentation AQP4-IgG Antibody Positive Neuromyelitis Optica in Patients of Advanced Age as a Possible Paraneoplastic Phenomenon. AAN 73rd Annual Meeting, Online, 17-22 April 2021. Ovid Technologies (Wolters Kluwer Health). doi: 10.1212/wnl.96.15_supplement.2975

Case Series: Two Cases of First Presentation AQP4-IgG Antibody Positive Neuromyelitis Optica in Patients of Advanced Age as a Possible Paraneoplastic Phenomenon

2021

Journal Article

A case of Anti-LGi1 antibody positive autoimmune epilepsy following deep brain stimulator implantation for essential tremor

Beer, Reuben, Lehn, Alex and Blum, Stefan (2021). A case of Anti-LGi1 antibody positive autoimmune epilepsy following deep brain stimulator implantation for essential tremor. Journal of Neuroimmunology, 353 577503, 1-2. doi: 10.1016/j.jneuroim.2021.577503

A case of Anti-LGi1 antibody positive autoimmune epilepsy following deep brain stimulator implantation for essential tremor

2021

Journal Article

Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy

Ioannides, Zara A., Csurhes, Peter A., Douglas, Nanette L., Mackenroth, Gem, Swayne, Andrew, Thompson, Kate M., Hopkins, Tracey J., Green, Kerryn A., Blum, Stefan, Hooper, Kaye D., Wyssusek, Kerstin H., Coulthard, Alan and Pender, Michael P. (2021). Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy. Frontiers in Neurology, 12 652811, 652811. doi: 10.3389/fneur.2021.652811

Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy

2021

Journal Article

A case of IVIg responsive paraneoplastic SOX1 peripheral neuropathy in a male with breast carcinoma

Beer, Reuben, O'Gorman, Cullen, Horwood, Keith and Blum, Stefan (2021). A case of IVIg responsive paraneoplastic SOX1 peripheral neuropathy in a male with breast carcinoma. Journal of Neuroimmunology, 352 577492, 577492. doi: 10.1016/j.jneuroim.2021.577492

A case of IVIg responsive paraneoplastic SOX1 peripheral neuropathy in a male with breast carcinoma

2021

Journal Article

An Australian state-based cohort study of autoimmune encephalitis cases detailing clinical presentation, investigation results, and response to therapy

Swayne, Andrew, Warren, Nicola, Prain, Kerri, Gillis, David, O'Gorman, Cullen, Tsang, Benjamin K-T., Muller, Claire, Broadley, Simon, Adam, Robert J., McCombe, Pamela, Wong, Richard C. and Blum, Stefan (2021). An Australian state-based cohort study of autoimmune encephalitis cases detailing clinical presentation, investigation results, and response to therapy. Frontiers in Neurology, 12 607773, 607773. doi: 10.3389/fneur.2021.607773

An Australian state-based cohort study of autoimmune encephalitis cases detailing clinical presentation, investigation results, and response to therapy

Funding

Past funding

  • 2020 - 2021
    Addressing the oral health needs of people with multiple sclerosis
    Multiple Sclerosis Research Australia
    Open grant
  • 2019 - 2021
    Social cognition, psychiatric comorbidities and quality of life in people with multiple sclerosis
    Multiple Sclerosis Research Australia
    Open grant
  • 2019 - 2021
    Identifying and treating patients with psychosis who are positive to anti-neuronal antibodies
    NHMRC Project Grant
    Open grant

Supervision

Availability

Associate Professor Stefan Blum is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Studies of myasthenia gravis using MGBase.

    Principal Advisor

    Other advisors: Professor Pamela McCombe

  • Doctor Philosophy

    Utilising multimodal MRI to model disease activity before and after highly active disease modifying therapy in newly diagnosed multiple sclerosis.

    Principal Advisor

Completed supervision

Media

Enquiries

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