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Professor Thomas Burne
Professor

Thomas Burne

Email: 

Overview

Background

Professor Burne is a leading Australian researcher in the field of biological psychiatry. Prof. Burne has >150 peer reviewed publications, which have attracted over 8500 citations (H-index 50). His research impact is evident by his 11 papers with >200 citations, with two recognised as Web of Science ‘Highly Cited Papers’. Together with collaborators he has been awarded >$8 million in research funding. Since 2003 he has supervised 17 PhD students, and 28 honours students Prof. Burne has a broad background in behavioural neuroscience, with specific training and expertise in animal models. As a Professorial Research Fellow with the Queensland Centre for Mental Health Research and Group Leader at the Queensland Brain Institute (QBI) the focus of his research includes cognitive testing in rodent models of neuropsychiatric disorders, such as schizophrenia, as well as psychopharmacological studies and research on clinical populations. As a CI on several university- and NHMRC-funded grants, he has helped establish infrastructure at QBI for behavioural assessment and methods of automated operant-based cognitive tests in rodents. Prof. Burne is a past president of Biological Psychiatry Australia, he is the Queensland representative for the Australasian Neuroscience Society, and he is a member of the NHMRC Animal Welfare Committee.

Prof. Burne’s group studies brain development and behaviour in animal models to learn more about neuropsychiatric diseases, such as schizophrenia. Research is focused on investigating the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease. The group has been exploring the impact of developmental vitamin D (DVD) deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour, and the neurobiological affects of having an older father. More recently his group has been focussed on assessing cognitive function in rodents. Prof. Burne’s research is carried out in close collaboration with Professors John McGrath and Darryl Eyles, in a multidisciplinary team. Together they have an integrated research program using a broad range of neuroscientific techniques to explore potential causes of schizophrenia. There is a particular focus on early life, nongenetic risk factors and the team has skills in epidemiology, psychiatry, neuroanatomy, molecular biology, developmental biology and behavioural neuroscience. The Burne group is currently developing animal models related to risk factors for schizophrenia and autism.

Availability

Professor Thomas Burne is:
Available for supervision
Media expert

Fields of research

Works

Search Professor Thomas Burne’s works on UQ eSpace

222 works between 1996 and 2024

41 - 60 of 222 works

2019

Journal Article

Cyclooctatetraene: a bioactive cubane paradigm complement

Xing, Hui, Houston, Sevan D., Chen, Xuejie, Ghassabian, Sussan, Fahrenhorst-Jones, Tyler, Kuo, Andy, Murray, Cody-Ellen P., Conn, Kyna-Anne, Jaeschke, Kara N., Jin, Da-Yun, Pasay, Cielo, Bernhardt, Paul V., Burns, Jed M., Tsanaktsidis, John, Savage, G. Paul, Boyle, Glen M., De Voss, James J., McCarthy, James, Walter, Gimme H., Burne, Thomas H. J., Smith, Maree T., Tie, Jian-Ke and Williams, Craig M. (2019). Cyclooctatetraene: a bioactive cubane paradigm complement. Chemistry: A European Journal, 25 (11), 2729-2734. doi: 10.1002/chem.201806277

Cyclooctatetraene: a bioactive cubane paradigm complement

2019

Journal Article

Adult vitamin D deficiency disrupts hippocampal-dependent learning and structural brain connectivity in BALB/c mice

Al-Amin, Md. Mamun, Sullivan, Robert K. P., Kurniawan, Nyoman D. and Burne, Thomas H. J. (2019). Adult vitamin D deficiency disrupts hippocampal-dependent learning and structural brain connectivity in BALB/c mice. Brain Structure and Function, 224 (3), 1315-1329. doi: 10.1007/s00429-019-01840-w

Adult vitamin D deficiency disrupts hippocampal-dependent learning and structural brain connectivity in BALB/c mice

2019

Journal Article

Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice

Sanchez Vega, M., Chong, S. and Burne, T.H.J. (2019). Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice. Behavioural Brain Research, 356, 127-136. doi: 10.1016/j.bbr.2018.08.018

Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice

2018

Journal Article

The association between neonatal vitamin D status and risk of schizophrenia

Eyles, Darryl W., Trzaskowski, Maciej, Vinkhuyzen, Anna A. E., Mattheisen, Manuel, Meier, Sandra, Gooch, Helen, Anggono, Victor, Cui, Xiaoying, Tan, Men Chee, Burne, Thomas H. J., Jang, Se Eun, Kvaskoff, David, Hougaard, David M., Nørgaard-Pedersen, Bent, Cohen, Arieh, Agerbo, Esben, Pedersen, Carsten B., Børglum, Anders D., Mors, Ole, Sah, Pankaj, Wray, Naomi R., Mortensen, Preben B. and McGrath, John J. (2018). The association between neonatal vitamin D status and risk of schizophrenia. Scientific Reports, 8 (1) 17692, 17692. doi: 10.1038/s41598-018-35418-z

The association between neonatal vitamin D status and risk of schizophrenia

2018

Journal Article

Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome

Oishi, Sabrina, Harkins, Danyon, Kurniawan, Nyoman D., Kasherman, Maria, Harris, Lachlan, Zalucki, Oressia, Gronostajski, Richard M., Burne, Thomas H.J. and Piper, Michael (2018). Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome. EBioMedicine, 39, 388-400. doi: 10.1016/j.ebiom.2018.11.044

Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome

2018

Journal Article

Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats

Lefevre, Emilia, Gooch, Helen, Josh, Peter, Alexander, Suzy, Eyles, Darryl W. and Burne, Thomas H. J. (2018). Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats. Behavioural Pharmacology, 30 (5), 1-395. doi: 10.1097/FBP.0000000000000447

Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats

2018

Journal Article

Increasing paternal age alters anxiety-related behaviour in adult mice

Foldi, Claire J., Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2018). Increasing paternal age alters anxiety-related behaviour in adult mice. Genes, Brain and Behavior, 18 (2) e12522, e12522. doi: 10.1111/gbb.12522

Increasing paternal age alters anxiety-related behaviour in adult mice

2018

Journal Article

Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors

Miliku, Kozeta, Felix, Janine F., Voortman, Trudy, Tiemeier, Henning, Eyles, Darryl W., Burne, Thomas H., McGrath, John J. and Jaddoe, Vincent W. V. (2018). Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors. Maternal and Child Nutrition, 15 (2) e12672, e12672. doi: 10.1111/mcn.12672

Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors

2018

Journal Article

Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells

Zalucki, Oressia, Harkins, Danyon, Harris, Lachlan, Burne, Thomas H. J., Gronostajski, Richard M. and Piper, Michael (2018). Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells. BMC Research Notes, 11 (1) 564, 564. doi: 10.1186/s13104-018-3652-7

Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells

2018

Journal Article

No effect of prenatal vitamin D deficiency on autism-relevant behaviours in multiple inbred strains of mice

Langguth, M., Fassin, M., Alexander, S., Turner, K. M. and Burne, T. H. J. (2018). No effect of prenatal vitamin D deficiency on autism-relevant behaviours in multiple inbred strains of mice. Behavioural Brain Research, 348, 42-52. doi: 10.1016/j.bbr.2018.04.004

No effect of prenatal vitamin D deficiency on autism-relevant behaviours in multiple inbred strains of mice

2018

Journal Article

Erratum: Correction: Transcriptional regulation of intermediate progenitor cell generation during hippocampal development (doi: 10.1242/dev.140681) (Development (Cambridge, England) (2016) 143 24 (4620-4630) PII: dev169631)

Harris, Lachlan, Zalucki, Oressia, Gobius, Ilan, McDonald, Hannah, Osinki, Jason, Harvey, Tracey J., Essebier, Alexandra, Vidovic, Diana, Gladwyn-Ng, Ivan, Burne, Thomas H., Heng, Julian I., Richards, Linda J., Gronostajski, Richard M. and Piper, Michael (2018). Erratum: Correction: Transcriptional regulation of intermediate progenitor cell generation during hippocampal development (doi: 10.1242/dev.140681) (Development (Cambridge, England) (2016) 143 24 (4620-4630) PII: dev169631). Development (Cambridge), 145 (14). doi: 10.1242/dev.169631

Erratum: Correction: Transcriptional regulation of intermediate progenitor cell generation during hippocampal development (doi: 10.1242/dev.140681) (Development (Cambridge, England) (2016) 143 24 (4620-4630) PII: dev169631)

2018

Journal Article

Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression

Harris, Lachlan, Zalucki, Oressia, Clément, Olivier, Fraser, James, Matuzelski, Elise, Oishi, Sabrina, Harvey, Tracey J., Burne, Thomas H. J., Heng, Julian Ik-Tsen, Gronostajski, Richard M. and Piper, Michael (2018). Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression. Development (Cambridge, England), 145 (3) dev155689, 1-12. doi: 10.1242/dev.155689

Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression

2018

Book Chapter

Adult vitamin D deficiency and adverse brain outcomes

Groves, Natalie J., McGrath, John J. and Burne, Thomas (2018). Adult vitamin D deficiency and adverse brain outcomes. Vitamin D: volume 2: health, disease and therapeutics. (pp. 1147-1158) edited by David Feldman, J. Wesley Pike, Roger Bouillon, Edward Giovannucci, David Goltzman and Martin Hewison. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-809963-6.00115-2

Adult vitamin D deficiency and adverse brain outcomes

2018

Journal Article

Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment

Al-Amin, Mamun, Bradford, DanaKai, Sullivan, Robert K. P., Kurniawan, Nyoman D., Moon, Yeonsil, Han, Seol-Heui, Zalesky, Andrew and Burne, Thomas H. J. (2018). Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment. Human Brain Mapping, 40 (2), 394-406. doi: 10.1002/hbm.24380

Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment

2017

Journal Article

Touchscreen-based visual discrimination and reversal tasks for mice to test cognitive flexibility

Turner, Karly M., Simpson, Christopher G. and Burne, Thomas H. J. (2017). Touchscreen-based visual discrimination and reversal tasks for mice to test cognitive flexibility. Bio-protocol, 7 (20) e2583, e2583. doi: 10.21769/bioprotoc.2583

Touchscreen-based visual discrimination and reversal tasks for mice to test cognitive flexibility

2017

Journal Article

Adult vitamin D deficiency exacerbates impairments caused by social stress in BALB/c and C57BL/6 mice

Groves, Natalie J., Zhou, Mei, Jhaveri, Dhanisha J., McGrath, John J. and Burne, Thomas H. J. (2017). Adult vitamin D deficiency exacerbates impairments caused by social stress in BALB/c and C57BL/6 mice. Psychoneuroendocrinology, 86, 53-63. doi: 10.1016/j.psyneuen.2017.09.003

Adult vitamin D deficiency exacerbates impairments caused by social stress in BALB/c and C57BL/6 mice

2017

Journal Article

A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus

Harris, Lachlan, Zalucki, Oressia, Oishi, Sabrina, Burne, Thomas H., Jhaveri, Dhanisha J. and Piper, Michael (2017). A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus. Developmental Dynamics, 247 (1), 194-200. doi: 10.1002/dvdy.24545

A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus

2017

Journal Article

Content specificity of attentional bias to threat in post-traumatic stress disorder

Zinchenko, A., Al-Amin, M. M., Alam, M. M., Mahmud, W., Kabir, N., Reza, H. M. and Burne, T. H. J. (2017). Content specificity of attentional bias to threat in post-traumatic stress disorder. Journal of Anxiety Disorders, 50, 33-39. doi: 10.1016/j.janxdis.2017.05.006

Content specificity of attentional bias to threat in post-traumatic stress disorder

2017

Journal Article

Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain

Kesby, James P., Turner, Karly M., Alexander, Suzanne, Eyles, Darryl W., McGrath, John J. and Burne, Thomas H.J. (2017). Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain. International Journal of Developmental Neuroscience, 62 (C), 1-7. doi: 10.1016/j.ijdevneu.2017.07.002

Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain

2017

Journal Article

Short- and long-term effects of risperidone on catalepsy sensitisation and acquisition of conditioned avoidance response: adolescent vs adult rats

Moe, Aung Aung Kywe, Medely, Gregory A., Reeks, Timothy, Burne, Thomas H. J. and Eyles, Darryl W. (2017). Short- and long-term effects of risperidone on catalepsy sensitisation and acquisition of conditioned avoidance response: adolescent vs adult rats. Pharmacological Research, 121, 1-13. doi: 10.1016/j.phrs.2017.04.013

Short- and long-term effects of risperidone on catalepsy sensitisation and acquisition of conditioned avoidance response: adolescent vs adult rats

Funding

Current funding

  • 2023 - 2025
    Lab based analysis of rodent blood and tissue in a rodent model of fetal growth restriction (FGR)
    CSIRO
    Open grant
  • 2023 - 2026
    Reverse translation of a rodent cognitive flexibility task
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2018
    A specialised surgical and behavioural facility for longitudinal, multimodal examination of the rodent brain
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016 - 2019
    Delayed radial glial maturation linked to NFI deficiency as an underlying cause of cortical defects in humans and mice
    NHMRC Project Grant
    Open grant
  • 2016
    Light-sheet microscope for high-speed 3D imaging of live organisms and fixed tissue
    NHMRC Equipment Grant
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015
    Reverse translation of cognitive tasks for animal models of neuropsychiatric disorders
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Adult vitamin D deficiency and cognitive dysfunction in a mouse model
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    The Developmental vitamin D-deficiency animal model of schizophrenia:- Critical window for intervention and optimal dose
    NHMRC Project Grant
    Open grant
  • 2014
    Touchscreen-automated cognitive testing for mice
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2016
    Early pharmacological intervention in an animal model of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Developmental vitamin D deficiency and prefrontal cortical dysfunction
    NHMRC Project Grant
    Open grant
  • 2011
    Advanced behavioural facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2014
    Attentional processing in developmentally vitamin D deficient rats: Modelling the cognitive symptoms of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Neonatal vitamin D status and risk of schizophrenia: a replication in two independent samples
    NHMRC Project Grant
    Open grant
  • 2010
    Zebrafish Aquarium - expand capacity of existing Zebrafish facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2011
    Zebrafish behavioural suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2012
    Advanced paternal age: behavioural, neuroanatomical and genomic correlates in the offspring of older fathers
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    The Developmental vitamin D model (DVD) as an animal model for schizophrenia
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Thomas Burne is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Measuring cognitive flexibility in rodents

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    The neural basis of predictive coding: Defining how the brain uses feedback to propagate predictions

    Associate Advisor

    Other advisors: Dr Clarissa Whitmire

Completed supervision

Media

Enquiries

Contact Professor Thomas Burne directly for media enquiries about:

  • Animal behaviour
  • Animal models
  • Behaviour in animals
  • Behavioural neuroscience
  • Behavioural phenotyping
  • Neuroscience - behavioural
  • Phenotyping - behavioural
  • Schizophrenia

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