
Overview
Background
Professor Burne is a leading Australian researcher in the field of biological psychiatry. Prof. Burne has >150 peer reviewed publications, which have attracted over 8500 citations (H-index 50). His research impact is evident by his 11 papers with >200 citations, with two recognised as Web of Science ‘Highly Cited Papers’. Together with collaborators he has been awarded >$8 million in research funding. Since 2003 he has supervised 17 PhD students, and 28 honours students Prof. Burne has a broad background in behavioural neuroscience, with specific training and expertise in animal models. As a Professorial Research Fellow with the Queensland Centre for Mental Health Research and Group Leader at the Queensland Brain Institute (QBI) the focus of his research includes cognitive testing in rodent models of neuropsychiatric disorders, such as schizophrenia, as well as psychopharmacological studies and research on clinical populations. As a CI on several university- and NHMRC-funded grants, he has helped establish infrastructure at QBI for behavioural assessment and methods of automated operant-based cognitive tests in rodents. Prof. Burne is a past president of Biological Psychiatry Australia, he is the Queensland representative for the Australasian Neuroscience Society, and he is a member of the NHMRC Animal Welfare Committee.
Prof. Burne’s group studies brain development and behaviour in animal models to learn more about neuropsychiatric diseases, such as schizophrenia. Research is focused on investigating the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease. The group has been exploring the impact of developmental vitamin D (DVD) deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour, and the neurobiological affects of having an older father. More recently his group has been focussed on assessing cognitive function in rodents. Prof. Burne’s research is carried out in close collaboration with Professors John McGrath and Darryl Eyles, in a multidisciplinary team. Together they have an integrated research program using a broad range of neuroscientific techniques to explore potential causes of schizophrenia. There is a particular focus on early life, nongenetic risk factors and the team has skills in epidemiology, psychiatry, neuroanatomy, molecular biology, developmental biology and behavioural neuroscience. The Burne group is currently developing animal models related to risk factors for schizophrenia and autism.
Availability
- Professor Thomas Burne is:
- Available for supervision
- Media expert
Fields of research
Works
Search Professor Thomas Burne’s works on UQ eSpace
2019
Journal Article
Vitamin D in synaptic plasticity, cognitive function, and neuropsychiatric illness
Mayne, Phoebe E. and Burne, Thomas H.J. (2019). Vitamin D in synaptic plasticity, cognitive function, and neuropsychiatric illness. Trends in Neurosciences, 42 (4), 293-306. doi: 10.1016/j.tins.2019.01.003
2019
Journal Article
Cyclooctatetraene: a bioactive cubane paradigm complement
Xing, Hui, Houston, Sevan D., Chen, Xuejie, Ghassabian, Sussan, Fahrenhorst-Jones, Tyler, Kuo, Andy, Murray, Cody-Ellen P., Conn, Kyna-Anne, Jaeschke, Kara N., Jin, Da-Yun, Pasay, Cielo, Bernhardt, Paul V., Burns, Jed M., Tsanaktsidis, John, Savage, G. Paul, Boyle, Glen M., De Voss, James J., McCarthy, James, Walter, Gimme H., Burne, Thomas H. J., Smith, Maree T., Tie, Jian-Ke and Williams, Craig M. (2019). Cyclooctatetraene: a bioactive cubane paradigm complement. Chemistry: A European Journal, 25 (11), 2729-2734. doi: 10.1002/chem.201806277
2019
Journal Article
Adult vitamin D deficiency disrupts hippocampal-dependent learning and structural brain connectivity in BALB/c mice
Al-Amin, Md. Mamun, Sullivan, Robert K. P., Kurniawan, Nyoman D. and Burne, Thomas H. J. (2019). Adult vitamin D deficiency disrupts hippocampal-dependent learning and structural brain connectivity in BALB/c mice. Brain Structure and Function, 224 (3), 1315-1329. doi: 10.1007/s00429-019-01840-w
2019
Journal Article
Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice
Sanchez Vega, M., Chong, S. and Burne, T.H.J. (2019). Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice. Behavioural Brain Research, 356, 127-136. doi: 10.1016/j.bbr.2018.08.018
2018
Journal Article
The association between neonatal vitamin D status and risk of schizophrenia
Eyles, Darryl W., Trzaskowski, Maciej, Vinkhuyzen, Anna A. E., Mattheisen, Manuel, Meier, Sandra, Gooch, Helen, Anggono, Victor, Cui, Xiaoying, Tan, Men Chee, Burne, Thomas H. J., Jang, Se Eun, Kvaskoff, David, Hougaard, David M., Nørgaard-Pedersen, Bent, Cohen, Arieh, Agerbo, Esben, Pedersen, Carsten B., Børglum, Anders D., Mors, Ole, Sah, Pankaj, Wray, Naomi R., Mortensen, Preben B. and McGrath, John J. (2018). The association between neonatal vitamin D status and risk of schizophrenia. Scientific Reports, 8 (1) 17692, 17692. doi: 10.1038/s41598-018-35418-z
2018
Journal Article
Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome
Oishi, Sabrina, Harkins, Danyon, Kurniawan, Nyoman D., Kasherman, Maria, Harris, Lachlan, Zalucki, Oressia, Gronostajski, Richard M., Burne, Thomas H.J. and Piper, Michael (2018). Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome. EBioMedicine, 39, 388-400. doi: 10.1016/j.ebiom.2018.11.044
2018
Journal Article
Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats
Lefevre, Emilia, Gooch, Helen, Josh, Peter, Alexander, Suzy, Eyles, Darryl W. and Burne, Thomas H. J. (2018). Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats. Behavioural Pharmacology, 30 (5), 1-395. doi: 10.1097/FBP.0000000000000447
2018
Journal Article
Increasing paternal age alters anxiety-related behaviour in adult mice
Foldi, Claire J., Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2018). Increasing paternal age alters anxiety-related behaviour in adult mice. Genes, Brain and Behavior, 18 (2) e12522, e12522. doi: 10.1111/gbb.12522
2018
Journal Article
Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors
Miliku, Kozeta, Felix, Janine F., Voortman, Trudy, Tiemeier, Henning, Eyles, Darryl W., Burne, Thomas H., McGrath, John J. and Jaddoe, Vincent W. V. (2018). Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors. Maternal and Child Nutrition, 15 (2) e12672, e12672. doi: 10.1111/mcn.12672
2018
Journal Article
Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells
Zalucki, Oressia, Harkins, Danyon, Harris, Lachlan, Burne, Thomas H. J., Gronostajski, Richard M. and Piper, Michael (2018). Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells. BMC Research Notes, 11 (1) 564, 564. doi: 10.1186/s13104-018-3652-7
2018
Journal Article
No effect of prenatal vitamin D deficiency on autism-relevant behaviours in multiple inbred strains of mice
Langguth, M., Fassin, M., Alexander, S., Turner, K. M. and Burne, T. H. J. (2018). No effect of prenatal vitamin D deficiency on autism-relevant behaviours in multiple inbred strains of mice. Behavioural Brain Research, 348, 42-52. doi: 10.1016/j.bbr.2018.04.004
2018
Journal Article
Erratum: Correction: Transcriptional regulation of intermediate progenitor cell generation during hippocampal development (doi: 10.1242/dev.140681) (Development (Cambridge, England) (2016) 143 24 (4620-4630) PII: dev169631)
Harris, Lachlan, Zalucki, Oressia, Gobius, Ilan, McDonald, Hannah, Osinki, Jason, Harvey, Tracey J., Essebier, Alexandra, Vidovic, Diana, Gladwyn-Ng, Ivan, Burne, Thomas H., Heng, Julian I., Richards, Linda J., Gronostajski, Richard M. and Piper, Michael (2018). Erratum: Correction: Transcriptional regulation of intermediate progenitor cell generation during hippocampal development (doi: 10.1242/dev.140681) (Development (Cambridge, England) (2016) 143 24 (4620-4630) PII: dev169631). Development (Cambridge), 145 (14). doi: 10.1242/dev.169631
2018
Journal Article
Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression
Harris, Lachlan, Zalucki, Oressia, Clément, Olivier, Fraser, James, Matuzelski, Elise, Oishi, Sabrina, Harvey, Tracey J., Burne, Thomas H. J., Heng, Julian Ik-Tsen, Gronostajski, Richard M. and Piper, Michael (2018). Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression. Development (Cambridge, England), 145 (3) dev155689, 1-12. doi: 10.1242/dev.155689
2018
Journal Article
Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment
Al-Amin, Mamun, Bradford, DanaKai, Sullivan, Robert K. P., Kurniawan, Nyoman D., Moon, Yeonsil, Han, Seol-Heui, Zalesky, Andrew and Burne, Thomas H. J. (2018). Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment. Human Brain Mapping, 40 (2), 394-406. doi: 10.1002/hbm.24380
2018
Book Chapter
Adult vitamin D deficiency and adverse brain outcomes
Groves, Natalie J., McGrath, John J. and Burne, Thomas (2018). Adult vitamin D deficiency and adverse brain outcomes. Vitamin D: volume 2: health, disease and therapeutics. (pp. 1147-1158) edited by David Feldman, J. Wesley Pike, Roger Bouillon, Edward Giovannucci, David Goltzman and Martin Hewison. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-809963-6.00115-2
2017
Journal Article
Touchscreen-based visual discrimination and reversal tasks for mice to test cognitive flexibility
Turner, Karly M., Simpson, Christopher G. and Burne, Thomas H. J. (2017). Touchscreen-based visual discrimination and reversal tasks for mice to test cognitive flexibility. Bio-protocol, 7 (20) e2583, e2583. doi: 10.21769/bioprotoc.2583
2017
Journal Article
Adult vitamin D deficiency exacerbates impairments caused by social stress in BALB/c and C57BL/6 mice
Groves, Natalie J., Zhou, Mei, Jhaveri, Dhanisha J., McGrath, John J. and Burne, Thomas H. J. (2017). Adult vitamin D deficiency exacerbates impairments caused by social stress in BALB/c and C57BL/6 mice. Psychoneuroendocrinology, 86, 53-63. doi: 10.1016/j.psyneuen.2017.09.003
2017
Journal Article
A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus
Harris, Lachlan, Zalucki, Oressia, Oishi, Sabrina, Burne, Thomas H., Jhaveri, Dhanisha J. and Piper, Michael (2017). A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus. Developmental Dynamics, 247 (1), 194-200. doi: 10.1002/dvdy.24545
2017
Journal Article
Content specificity of attentional bias to threat in post-traumatic stress disorder
Zinchenko, A., Al-Amin, M. M., Alam, M. M., Mahmud, W., Kabir, N., Reza, H. M. and Burne, T. H. J. (2017). Content specificity of attentional bias to threat in post-traumatic stress disorder. Journal of Anxiety Disorders, 50, 33-39. doi: 10.1016/j.janxdis.2017.05.006
2017
Journal Article
Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain
Kesby, James P., Turner, Karly M., Alexander, Suzanne, Eyles, Darryl W., McGrath, John J. and Burne, Thomas H.J. (2017). Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain. International Journal of Developmental Neuroscience, 62 (C), 1-7. doi: 10.1016/j.ijdevneu.2017.07.002
Funding
Current funding
Supervision
Availability
- Professor Thomas Burne is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Measuring cognitive flexibility in rodents
Principal Advisor
Other advisors: Professor Dan Siskind
-
Doctor Philosophy
The neural basis of predictive coding: Defining how the brain uses feedback to propagate predictions
Associate Advisor
Other advisors: Dr Clarissa Whitmire
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Master Philosophy
Investigating neural population dynamics in the mouse somatosensory thalamus
Associate Advisor
Other advisors: Dr Clarissa Whitmire
Completed supervision
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2024
Doctor Philosophy
The role of perineuronal nets in spatial learning and memory: Implications for schizophrenia
Principal Advisor
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2023
Doctor Philosophy
Measuring and improving cognition in a rodent model relevant to schizophrenia
Principal Advisor
Other advisors: Professor Dan Siskind, Dr James Kesby
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2021
Doctor Philosophy
Dissecting mechanisms underlying decision-making dysfunction in schizophrenia using preclinical animal models
Principal Advisor
Other advisors: Dr James Kesby
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2019
Doctor Philosophy
Does adult vitamin D deficiency alter cognition and hippocampal function?
Principal Advisor
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2018
Doctor Philosophy
Effects of developmental vitamin D deficiency and prenatal exposure to ethanol on brain development and behaviour in mice
Principal Advisor
-
2016
Doctor Philosophy
Neural mechanisms of MK-801 induced sensitisation
Principal Advisor
Other advisors: Professor Darryl Eyles
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2016
Doctor Philosophy
Establishing novel cognitive tasks in animal models relevant to schizophrenia
Principal Advisor
Other advisors: Professor Darryl Eyles
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2016
Doctor Philosophy
The role of adult vitamin D deficiency in cognition and brain function in mice
Principal Advisor
Other advisors: Professor John McGrath
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2012
Doctor Philosophy
The effects of Advanced Paternal Age (APA) on behavioural and brain structural phenotypes in C57BL/6J mice.
Principal Advisor
Other advisors: Professor Darryl Eyles
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2012
Doctor Philosophy
Brain Development and Behaviour in Developmentally Vitamin D-Deficient Mice
Principal Advisor
Other advisors: Professor Darryl Eyles
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2010
Doctor Philosophy
The impact of developmental vitamin D deficiency on brain neurochemistry and behaviour in Sprague-Dawley rats
Joint Principal Advisor
Other advisors: Professor Darryl Eyles
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2017
Doctor Philosophy
The function of NFIX during developmental and adult neurogenesis
Associate Advisor
Other advisors: Professor Michael Piper
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2016
Doctor Philosophy
Evaluating long-term consequences of adolescent antipsychotic exposure
Associate Advisor
Other advisors: Professor Darryl Eyles
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2014
Doctor Philosophy
Brain structure and function in a mouse model of moderate prenatal ethanol exposure
Associate Advisor
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2014
Doctor Philosophy
The Long Term Neurobehavioral Correlates of Chronic Low Dose Prenatal Alcohol Exposure
Associate Advisor
Other advisors: Professor Karen Moritz
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2009
Doctor Philosophy
The effect of developmental vitamin D3 deficiency on brain development, immune function and behaviour in the adult rat
Associate Advisor
Other advisors: Professor John McGrath, Professor Darryl Eyles
Media
Enquiries
Contact Professor Thomas Burne directly for media enquiries about:
- Animal behaviour
- Animal models
- Behaviour in animals
- Behavioural neuroscience
- Behavioural phenotyping
- Neuroscience - behavioural
- Phenotyping - behavioural
- Schizophrenia
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