
Overview
Background
Professor Burne is a leading Australian researcher in the field of biological psychiatry. Prof. Burne has >150 peer reviewed publications, which have attracted over 8500 citations (H-index 50). His research impact is evident by his 11 papers with >200 citations, with two recognised as Web of Science ‘Highly Cited Papers’. Together with collaborators he has been awarded >$8 million in research funding. Since 2003 he has supervised 17 PhD students, and 28 honours students Prof. Burne has a broad background in behavioural neuroscience, with specific training and expertise in animal models. As a Professorial Research Fellow with the Queensland Centre for Mental Health Research and Group Leader at the Queensland Brain Institute (QBI) the focus of his research includes cognitive testing in rodent models of neuropsychiatric disorders, such as schizophrenia, as well as psychopharmacological studies and research on clinical populations. As a CI on several university- and NHMRC-funded grants, he has helped establish infrastructure at QBI for behavioural assessment and methods of automated operant-based cognitive tests in rodents. Prof. Burne is a past president of Biological Psychiatry Australia, he is the Queensland representative for the Australasian Neuroscience Society, and he is a member of the NHMRC Animal Welfare Committee.
Prof. Burne’s group studies brain development and behaviour in animal models to learn more about neuropsychiatric diseases, such as schizophrenia. Research is focused on investigating the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease. The group has been exploring the impact of developmental vitamin D (DVD) deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour, and the neurobiological affects of having an older father. More recently his group has been focussed on assessing cognitive function in rodents. Prof. Burne’s research is carried out in close collaboration with Professors John McGrath and Darryl Eyles, in a multidisciplinary team. Together they have an integrated research program using a broad range of neuroscientific techniques to explore potential causes of schizophrenia. There is a particular focus on early life, nongenetic risk factors and the team has skills in epidemiology, psychiatry, neuroanatomy, molecular biology, developmental biology and behavioural neuroscience. The Burne group is currently developing animal models related to risk factors for schizophrenia and autism.
Availability
- Professor Thomas Burne is:
- Available for supervision
- Media expert
Fields of research
Works
Search Professor Thomas Burne’s works on UQ eSpace
2013
Journal Article
Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice
Harris, Lachlan, Dixon, Chantelle, Cato, Kathleen, Heng, Yee Hsieh Evelyn, Kurniawan, Nyoman D., Ullmann, Jeremy F. P., Janke, Andrew L., Gronostajski, Richard M., Richards, Linda J., Burne, Thomas H. J. and Piper, Michael (2013). Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice. PLoS ONE, 8 (6) e65478, e65478. doi: 10.1371/journal.pone.0065478
2013
Journal Article
Low vitamin D concentration exacerbates adult brain dysfunction
Cui, Xiaoying, Groves, Natalie J., Burne, Thomas H. J., Eyles, Darryl W. and McGrath, John J. (2013). Low vitamin D concentration exacerbates adult brain dysfunction. American Journal of Clinical Nutrition, 97 (5), 907-908. doi: 10.3945/ajcn.113.061176
2013
Journal Article
The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain
Cui, X., Pelekanos, M., Liu, P-Y, Burne, T. H. J., McGrath, J. J. and Eyles, D. W. (2013). The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain. Neuroscience, 236, 77-87. doi: 10.1016/j.neuroscience.2013.01.035
2013
Journal Article
Effect of vitamin D deficiency during pregnancy on offspring bone structure, composition and quality in later life
Lanham, S. A., Roberts, C., Habgood, A. K., Alexander, S., Burne, T. H. J., Eyles, D. W., Trueman, C. N., Cooper, M., McGrath, J. J. and Oreffo, R. O. C. (2013). Effect of vitamin D deficiency during pregnancy on offspring bone structure, composition and quality in later life. Journal of Developmental Origins of Health and Disease, 4 (1), 49-55. doi: 10.1017/S2040174412000542
2013
Journal Article
Low Dose Prenatal Ethanol Exposure Induces Anxiety-Like Behaviour and Alters Dendritic Morphology in the Basolateral Amygdala of Rat Offspring
Cullen, Carlie L., Burne, Thomas H. J., Lavidis, Nickolas A. and Moritz, Karen M. (2013). Low Dose Prenatal Ethanol Exposure Induces Anxiety-Like Behaviour and Alters Dendritic Morphology in the Basolateral Amygdala of Rat Offspring. PLoS One, 8 (1) e54924, e54924. doi: 10.1371/journal.pone.0054924
2013
Journal Article
Digital lecture recording: a cautionary tale
Johnston, Amy N. B., Massa, Helen and Burne, Thomas H. J. (2013). Digital lecture recording: a cautionary tale. Nurse Education in Practice, 13 (1), 40-47. doi: 10.1016/j.nepr.2012.07.004
2012
Journal Article
The neurodevelopmental hypothesis of schizophrenia: Convergent clues from epidemiology and neuropathology
Piper, Michael, Beneyto, Monica, Burne, Thomas H. J., Eyles, Darryl W., Lewis, David A. and McGrath, John J. (2012). The neurodevelopmental hypothesis of schizophrenia: Convergent clues from epidemiology and neuropathology. Psychiatric Clinics of North America, 35 (3), 571-584. doi: 10.1016/j.psc.2012.06.002
2012
Journal Article
Transient knockdown of tyrosine hydroxylase during development has persistent effects on behaviour in adult zebrafish (Danio rerio)
Formella, Isabel, Scott, Ethan, Burne, Thomas H.J., Lauren Harms, Liu, Pei-Yun, Karly Turner, Cui, Xiaoying and Eyles, Darryl (2012). Transient knockdown of tyrosine hydroxylase during development has persistent effects on behaviour in adult zebrafish (Danio rerio). PLoS ONE, 7 (8) e42482, e42482.1-e42482.8. doi: 10.1371/journal.pone.0042482
2012
Journal Article
Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency
Harms, Lauren R., Cowin, Gary, Eyles, Darryl W., Kurniawan, Nyoman D., McGrath, John J. and Burne, Thomas H. J. (2012). Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency. Behavioural Brain Research, 230 (1), 125-131. doi: 10.1016/j.bbr.2012.02.007
2012
Journal Article
Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency
Harms, Lauren R., Turner, Karly M., Eyles, Darryl W., Young, Jared W., McGrath, John J. and Burne, Thomas H. J. (2012). Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency. PLoS One, 7 (4 Article No. ee35896) e35896, e35896. doi: 10.1371/journal.pone.0035896
2012
Journal Article
Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring
Kesby, James P., O'Loan, Jonathan C., Alexander, Suzanne, Deng, Chao, Huang, Xu-Feng, McGrath, John J., Eyles, Darryl W. and Burne, Thomas H. J. (2012). Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring. Psychopharmacology, 220 (3), 455-463. doi: 10.1007/s00213-011-2492-0
2012
Book Chapter
Developmental vitamin D deficiency as a risk factor for schizophrenia
Cui, Xiaoying, Eyles, Darryl W., Burne, Thomas H. J. and McGrath, John J. (2012). Developmental vitamin D deficiency as a risk factor for schizophrenia. The origins of schizophrenia. (pp. 282-299) edited by Alan S. Brown and Paul H. Patterson. New York, United States: Columbia University Press.
2012
Conference Publication
Increased de novo copy number variants in the offspring of older males
McGrath, John J., Flatscher-Bader, Traute, Foldi, Claire J., Chong, Suyinn, Whitelaw, Emma, Moser, Ralf J., Burne, Thomas H.J and Eyles, Darryl W. (2012). Increased de novo copy number variants in the offspring of older males. 3rd Biennial Schizophrenia International Research Conference, Florence, Italy, 14-18 April 2012. AMSTERDAM: Elsevier. doi: 10.1016/s0920-9964(12)70013-0
2012
Conference Publication
Prenatal vitamin D deficiency alters dopamine and glutamate metabolism in rat brain
Burne, Thomas H., Kesby, James P., Turner, Karly, Suzy, Alexander, McGrath, John J. and Eyles, Darryl W. (2012). Prenatal vitamin D deficiency alters dopamine and glutamate metabolism in rat brain. 3rd Biennial Schizophrenia International Research Conference, Florence, Italy, 14-18 April 2012. Amsterdam, Netherlands: Elsevier.
2012
Book
Schizophrenia in the 21st Century
T. H. J. Burne ed. (2012). Schizophrenia in the 21st Century. Rijeka, Croatia: InTech. doi: 10.5772/1669
2011
Journal Article
The effects of vitamin D on brain development and adult brain function
James Kesby, Eyles, Darryl, Burne, Thomas H.J. and McGrath, John J. (2011). The effects of vitamin D on brain development and adult brain function. Molecular and Cellular Endocrinology, 347 (1-2), 121-127. doi: 10.1016/j.mce.2011.05.014
2011
Journal Article
Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?
Karl, T., Burne, T. H. J., van den Buuse, M. and Chesworth, R. (2011). Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?. Behavioural Brain Research, 223 (2), 336-341. doi: 10.1016/j.bbr.2011.04.051
2011
Journal Article
Vitamin D and the brain
Harms, Lauren R., Burne, Thomas H. J., Eyles, Darryl W. and McGrath, John J. (2011). Vitamin D and the brain. Best Practice and Research: Clinical Endocrinology and Metabolism, 25 (4), 657-669. doi: 10.1016/j.beem.2011.05.009
2011
Journal Article
Vitamin D in fetal brain development
Eyles, Darryl, Burne, Thomas and McGrath, John (2011). Vitamin D in fetal brain development. Seminars in Cell and Developmental Biology, 22 (6), 629-636. doi: 10.1016/j.semcdb.2011.05.004
2011
Journal Article
New perspectives on rodent models of advanced paternal age: Relevance to autism
Foldi, Claire J., Eyles, Darryl W., Flatscher-Bader, Traute, McGrath, John J. and Burne, Thomas H. J. (2011). New perspectives on rodent models of advanced paternal age: Relevance to autism. Frontiers in Behavioral Neuroscience, 5 (32) 32, 1-7. doi: 10.3389/fnbeh.2011.00032
Funding
Current funding
Supervision
Availability
- Professor Thomas Burne is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Measuring cognitive flexibility in rodents
Principal Advisor
Other advisors: Professor Dan Siskind
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Doctor Philosophy
The neural basis of predictive coding: Defining how the brain uses feedback to propagate predictions
Associate Advisor
Other advisors: Dr Clarissa Whitmire
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Master Philosophy
Investigating neural population dynamics in the mouse somatosensory thalamus
Associate Advisor
Other advisors: Dr Clarissa Whitmire
Completed supervision
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2024
Doctor Philosophy
The role of perineuronal nets in spatial learning and memory: Implications for schizophrenia
Principal Advisor
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2023
Doctor Philosophy
Measuring and improving cognition in a rodent model relevant to schizophrenia
Principal Advisor
Other advisors: Professor Dan Siskind, Dr James Kesby
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2021
Doctor Philosophy
Dissecting mechanisms underlying decision-making dysfunction in schizophrenia using preclinical animal models
Principal Advisor
Other advisors: Dr James Kesby
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2019
Doctor Philosophy
Does adult vitamin D deficiency alter cognition and hippocampal function?
Principal Advisor
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2018
Doctor Philosophy
Effects of developmental vitamin D deficiency and prenatal exposure to ethanol on brain development and behaviour in mice
Principal Advisor
-
2016
Doctor Philosophy
Neural mechanisms of MK-801 induced sensitisation
Principal Advisor
Other advisors: Professor Darryl Eyles
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2016
Doctor Philosophy
Establishing novel cognitive tasks in animal models relevant to schizophrenia
Principal Advisor
Other advisors: Professor Darryl Eyles
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2016
Doctor Philosophy
The role of adult vitamin D deficiency in cognition and brain function in mice
Principal Advisor
Other advisors: Professor John McGrath
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2012
Doctor Philosophy
The effects of Advanced Paternal Age (APA) on behavioural and brain structural phenotypes in C57BL/6J mice.
Principal Advisor
Other advisors: Professor Darryl Eyles
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2012
Doctor Philosophy
Brain Development and Behaviour in Developmentally Vitamin D-Deficient Mice
Principal Advisor
Other advisors: Professor Darryl Eyles
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2010
Doctor Philosophy
The impact of developmental vitamin D deficiency on brain neurochemistry and behaviour in Sprague-Dawley rats
Joint Principal Advisor
Other advisors: Professor Darryl Eyles
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2017
Doctor Philosophy
The function of NFIX during developmental and adult neurogenesis
Associate Advisor
Other advisors: Professor Michael Piper
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2016
Doctor Philosophy
Evaluating long-term consequences of adolescent antipsychotic exposure
Associate Advisor
Other advisors: Professor Darryl Eyles
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2014
Doctor Philosophy
Brain structure and function in a mouse model of moderate prenatal ethanol exposure
Associate Advisor
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2014
Doctor Philosophy
The Long Term Neurobehavioral Correlates of Chronic Low Dose Prenatal Alcohol Exposure
Associate Advisor
Other advisors: Professor Karen Moritz
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2009
Doctor Philosophy
The effect of developmental vitamin D3 deficiency on brain development, immune function and behaviour in the adult rat
Associate Advisor
Other advisors: Professor John McGrath, Professor Darryl Eyles
Media
Enquiries
Contact Professor Thomas Burne directly for media enquiries about:
- Animal behaviour
- Animal models
- Behaviour in animals
- Behavioural neuroscience
- Behavioural phenotyping
- Neuroscience - behavioural
- Phenotyping - behavioural
- Schizophrenia
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