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Professor Thomas Burne
Professor

Thomas Burne

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Overview

Background

Professor Burne is a leading Australian researcher in the field of biological psychiatry. Prof. Burne has >150 peer reviewed publications, which have attracted over 8500 citations (H-index 50). His research impact is evident by his 11 papers with >200 citations, with two recognised as Web of Science ‘Highly Cited Papers’. Together with collaborators he has been awarded >$8 million in research funding. Since 2003 he has supervised 17 PhD students, and 28 honours students Prof. Burne has a broad background in behavioural neuroscience, with specific training and expertise in animal models. As a Professorial Research Fellow with the Queensland Centre for Mental Health Research and Group Leader at the Queensland Brain Institute (QBI) the focus of his research includes cognitive testing in rodent models of neuropsychiatric disorders, such as schizophrenia, as well as psychopharmacological studies and research on clinical populations. As a CI on several university- and NHMRC-funded grants, he has helped establish infrastructure at QBI for behavioural assessment and methods of automated operant-based cognitive tests in rodents. Prof. Burne is a past president of Biological Psychiatry Australia, he is the Queensland representative for the Australasian Neuroscience Society, and he is a member of the NHMRC Animal Welfare Committee.

Prof. Burne’s group studies brain development and behaviour in animal models to learn more about neuropsychiatric diseases, such as schizophrenia. Research is focused on investigating the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease. The group has been exploring the impact of developmental vitamin D (DVD) deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour, and the neurobiological affects of having an older father. More recently his group has been focussed on assessing cognitive function in rodents. Prof. Burne’s research is carried out in close collaboration with Professors John McGrath and Darryl Eyles, in a multidisciplinary team. Together they have an integrated research program using a broad range of neuroscientific techniques to explore potential causes of schizophrenia. There is a particular focus on early life, nongenetic risk factors and the team has skills in epidemiology, psychiatry, neuroanatomy, molecular biology, developmental biology and behavioural neuroscience. The Burne group is currently developing animal models related to risk factors for schizophrenia and autism.

Availability

Professor Thomas Burne is:
Available for supervision
Media expert

Fields of research

Works

Search Professor Thomas Burne’s works on UQ eSpace

223 works between 1996 and 2024

101 - 120 of 223 works

2013

Journal Article

Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice

Harris, Lachlan, Dixon, Chantelle, Cato, Kathleen, Heng, Yee Hsieh Evelyn, Kurniawan, Nyoman D., Ullmann, Jeremy F. P., Janke, Andrew L., Gronostajski, Richard M., Richards, Linda J., Burne, Thomas H. J. and Piper, Michael (2013). Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice. PLoS ONE, 8 (6) e65478, e65478. doi: 10.1371/journal.pone.0065478

Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice

2013

Journal Article

Low vitamin D concentration exacerbates adult brain dysfunction

Cui, Xiaoying, Groves, Natalie J., Burne, Thomas H. J., Eyles, Darryl W. and McGrath, John J. (2013). Low vitamin D concentration exacerbates adult brain dysfunction. American Journal of Clinical Nutrition, 97 (5), 907-908. doi: 10.3945/ajcn.113.061176

Low vitamin D concentration exacerbates adult brain dysfunction

2013

Journal Article

The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain

Cui, X., Pelekanos, M., Liu, P-Y, Burne, T. H. J., McGrath, J. J. and Eyles, D. W. (2013). The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain. Neuroscience, 236, 77-87. doi: 10.1016/j.neuroscience.2013.01.035

The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain

2013

Journal Article

Effect of vitamin D deficiency during pregnancy on offspring bone structure, composition and quality in later life

Lanham, S. A., Roberts, C., Habgood, A. K., Alexander, S., Burne, T. H. J., Eyles, D. W., Trueman, C. N., Cooper, M., McGrath, J. J. and Oreffo, R. O. C. (2013). Effect of vitamin D deficiency during pregnancy on offspring bone structure, composition and quality in later life. Journal of Developmental Origins of Health and Disease, 4 (1), 49-55. doi: 10.1017/S2040174412000542

Effect of vitamin D deficiency during pregnancy on offspring bone structure, composition and quality in later life

2013

Journal Article

Low Dose Prenatal Ethanol Exposure Induces Anxiety-Like Behaviour and Alters Dendritic Morphology in the Basolateral Amygdala of Rat Offspring

Cullen, Carlie L., Burne, Thomas H. J., Lavidis, Nickolas A. and Moritz, Karen M. (2013). Low Dose Prenatal Ethanol Exposure Induces Anxiety-Like Behaviour and Alters Dendritic Morphology in the Basolateral Amygdala of Rat Offspring. PLoS One, 8 (1) e54924, e54924. doi: 10.1371/journal.pone.0054924

Low Dose Prenatal Ethanol Exposure Induces Anxiety-Like Behaviour and Alters Dendritic Morphology in the Basolateral Amygdala of Rat Offspring

2013

Journal Article

Digital lecture recording: a cautionary tale

Johnston, Amy N. B., Massa, Helen and Burne, Thomas H. J. (2013). Digital lecture recording: a cautionary tale. Nurse Education in Practice, 13 (1), 40-47. doi: 10.1016/j.nepr.2012.07.004

Digital lecture recording: a cautionary tale

2012

Journal Article

The neurodevelopmental hypothesis of schizophrenia: Convergent clues from epidemiology and neuropathology

Piper, Michael, Beneyto, Monica, Burne, Thomas H. J., Eyles, Darryl W., Lewis, David A. and McGrath, John J. (2012). The neurodevelopmental hypothesis of schizophrenia: Convergent clues from epidemiology and neuropathology. Psychiatric Clinics of North America, 35 (3), 571-584. doi: 10.1016/j.psc.2012.06.002

The neurodevelopmental hypothesis of schizophrenia: Convergent clues from epidemiology and neuropathology

2012

Journal Article

Transient knockdown of tyrosine hydroxylase during development has persistent effects on behaviour in adult zebrafish (Danio rerio)

Formella, Isabel, Scott, Ethan, Burne, Thomas H.J., Lauren Harms, Liu, Pei-Yun, Karly Turner, Cui, Xiaoying and Eyles, Darryl (2012). Transient knockdown of tyrosine hydroxylase during development has persistent effects on behaviour in adult zebrafish (Danio rerio). PLoS ONE, 7 (8) e42482, e42482.1-e42482.8. doi: 10.1371/journal.pone.0042482

Transient knockdown of tyrosine hydroxylase during development has persistent effects on behaviour in adult zebrafish (Danio rerio)

2012

Journal Article

Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency

Harms, Lauren R., Cowin, Gary, Eyles, Darryl W., Kurniawan, Nyoman D., McGrath, John J. and Burne, Thomas H. J. (2012). Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency. Behavioural Brain Research, 230 (1), 125-131. doi: 10.1016/j.bbr.2012.02.007

Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency

2012

Journal Article

Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency

Harms, Lauren R., Turner, Karly M., Eyles, Darryl W., Young, Jared W., McGrath, John J. and Burne, Thomas H. J. (2012). Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency. PLoS One, 7 (4 Article No. ee35896) e35896, e35896. doi: 10.1371/journal.pone.0035896

Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency

2012

Journal Article

Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring

Kesby, James P., O'Loan, Jonathan C., Alexander, Suzanne, Deng, Chao, Huang, Xu-Feng, McGrath, John J., Eyles, Darryl W. and Burne, Thomas H. J. (2012). Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring. Psychopharmacology, 220 (3), 455-463. doi: 10.1007/s00213-011-2492-0

Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring

2012

Book Chapter

Developmental vitamin D deficiency as a risk factor for schizophrenia

Cui, Xiaoying, Eyles, Darryl W., Burne, Thomas H. J. and McGrath, John J. (2012). Developmental vitamin D deficiency as a risk factor for schizophrenia. The origins of schizophrenia. (pp. 282-299) edited by Alan S. Brown and Paul H. Patterson. New York, United States: Columbia University Press.

Developmental vitamin D deficiency as a risk factor for schizophrenia

2012

Conference Publication

Increased de novo copy number variants in the offspring of older males

McGrath, John J., Flatscher-Bader, Traute, Foldi, Claire J., Chong, Suyinn, Whitelaw, Emma, Moser, Ralf J., Burne, Thomas H.J and Eyles, Darryl W. (2012). Increased de novo copy number variants in the offspring of older males. 3rd Biennial Schizophrenia International Research Conference, Florence, Italy, 14-18 April 2012. AMSTERDAM: Elsevier. doi: 10.1016/s0920-9964(12)70013-0

Increased de novo copy number variants in the offspring of older males

2012

Conference Publication

Prenatal vitamin D deficiency alters dopamine and glutamate metabolism in rat brain

Burne, Thomas H., Kesby, James P., Turner, Karly, Suzy, Alexander, McGrath, John J. and Eyles, Darryl W. (2012). Prenatal vitamin D deficiency alters dopamine and glutamate metabolism in rat brain. 3rd Biennial Schizophrenia International Research Conference, Florence, Italy, 14-18 April 2012. Amsterdam, Netherlands: Elsevier.

Prenatal vitamin D deficiency alters dopamine and glutamate metabolism in rat brain

2012

Book

Schizophrenia in the 21st Century

T. H. J. Burne ed. (2012). Schizophrenia in the 21st Century. Rijeka, Croatia: InTech. doi: 10.5772/1669

Schizophrenia in the 21st Century

2011

Journal Article

The effects of vitamin D on brain development and adult brain function

James Kesby, Eyles, Darryl, Burne, Thomas H.J. and McGrath, John J. (2011). The effects of vitamin D on brain development and adult brain function. Molecular and Cellular Endocrinology, 347 (1-2), 121-127. doi: 10.1016/j.mce.2011.05.014

The effects of vitamin D on brain development and adult brain function

2011

Journal Article

Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?

Karl, T., Burne, T. H. J., van den Buuse, M. and Chesworth, R. (2011). Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?. Behavioural Brain Research, 223 (2), 336-341. doi: 10.1016/j.bbr.2011.04.051

Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?

2011

Journal Article

Vitamin D and the brain

Harms, Lauren R., Burne, Thomas H. J., Eyles, Darryl W. and McGrath, John J. (2011). Vitamin D and the brain. Best Practice and Research: Clinical Endocrinology and Metabolism, 25 (4), 657-669. doi: 10.1016/j.beem.2011.05.009

Vitamin D and the brain

2011

Journal Article

Vitamin D in fetal brain development

Eyles, Darryl, Burne, Thomas and McGrath, John (2011). Vitamin D in fetal brain development. Seminars in Cell and Developmental Biology, 22 (6), 629-636. doi: 10.1016/j.semcdb.2011.05.004

Vitamin D in fetal brain development

2011

Journal Article

New perspectives on rodent models of advanced paternal age: Relevance to autism

Foldi, Claire J., Eyles, Darryl W., Flatscher-Bader, Traute, McGrath, John J. and Burne, Thomas H. J. (2011). New perspectives on rodent models of advanced paternal age: Relevance to autism. Frontiers in Behavioral Neuroscience, 5 (32) 32, 1-7. doi: 10.3389/fnbeh.2011.00032

New perspectives on rodent models of advanced paternal age: Relevance to autism

Funding

Current funding

  • 2025 - 2028
    Time to wake up! Reversing a presynaptic anaesthetic mechanism
    NHMRC IDEAS Grants
    Open grant
  • 2023 - 2025
    Lab based analysis of rodent blood and tissue in a rodent model of fetal growth restriction (FGR)
    CSIRO
    Open grant
  • 2023 - 2026
    Reverse translation of a rodent cognitive flexibility task
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2018
    A specialised surgical and behavioural facility for longitudinal, multimodal examination of the rodent brain
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016 - 2019
    Delayed radial glial maturation linked to NFI deficiency as an underlying cause of cortical defects in humans and mice
    NHMRC Project Grant
    Open grant
  • 2016
    Light-sheet microscope for high-speed 3D imaging of live organisms and fixed tissue
    NHMRC Equipment Grant
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015
    Reverse translation of cognitive tasks for animal models of neuropsychiatric disorders
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Adult vitamin D deficiency and cognitive dysfunction in a mouse model
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    The Developmental vitamin D-deficiency animal model of schizophrenia:- Critical window for intervention and optimal dose
    NHMRC Project Grant
    Open grant
  • 2014
    Touchscreen-automated cognitive testing for mice
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2016
    Early pharmacological intervention in an animal model of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Developmental vitamin D deficiency and prefrontal cortical dysfunction
    NHMRC Project Grant
    Open grant
  • 2011
    Advanced behavioural facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2014
    Attentional processing in developmentally vitamin D deficient rats: Modelling the cognitive symptoms of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Neonatal vitamin D status and risk of schizophrenia: a replication in two independent samples
    NHMRC Project Grant
    Open grant
  • 2010
    Zebrafish Aquarium - expand capacity of existing Zebrafish facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2011
    Zebrafish behavioural suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2012
    Advanced paternal age: behavioural, neuroanatomical and genomic correlates in the offspring of older fathers
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    The Developmental vitamin D model (DVD) as an animal model for schizophrenia
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Thomas Burne is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Measuring cognitive flexibility in rodents

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    The neural basis of predictive coding: Defining how the brain uses feedback to propagate predictions

    Associate Advisor

    Other advisors: Dr Clarissa Whitmire

  • Master Philosophy

    Investigating neural population dynamics in the mouse somatosensory thalamus

    Associate Advisor

    Other advisors: Dr Clarissa Whitmire

Completed supervision

Media

Enquiries

Contact Professor Thomas Burne directly for media enquiries about:

  • Animal behaviour
  • Animal models
  • Behaviour in animals
  • Behavioural neuroscience
  • Behavioural phenotyping
  • Neuroscience - behavioural
  • Phenotyping - behavioural
  • Schizophrenia

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