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Professor Thomas Burne
Professor

Thomas Burne

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Overview

Background

Professor Burne is a leading Australian researcher in the field of biological psychiatry. Prof. Burne has >150 peer reviewed publications, which have attracted over 8500 citations (H-index 50). His research impact is evident by his 11 papers with >200 citations, with two recognised as Web of Science ‘Highly Cited Papers’. Together with collaborators he has been awarded >$8 million in research funding. Since 2003 he has supervised 17 PhD students, and 28 honours students Prof. Burne has a broad background in behavioural neuroscience, with specific training and expertise in animal models. As a Professorial Research Fellow with the Queensland Centre for Mental Health Research and Group Leader at the Queensland Brain Institute (QBI) the focus of his research includes cognitive testing in rodent models of neuropsychiatric disorders, such as schizophrenia, as well as psychopharmacological studies and research on clinical populations. As a CI on several university- and NHMRC-funded grants, he has helped establish infrastructure at QBI for behavioural assessment and methods of automated operant-based cognitive tests in rodents. Prof. Burne is a past president of Biological Psychiatry Australia, he is the Queensland representative for the Australasian Neuroscience Society, and he is a member of the NHMRC Animal Welfare Committee.

Prof. Burne’s group studies brain development and behaviour in animal models to learn more about neuropsychiatric diseases, such as schizophrenia. Research is focused on investigating the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease. The group has been exploring the impact of developmental vitamin D (DVD) deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour, and the neurobiological affects of having an older father. More recently his group has been focussed on assessing cognitive function in rodents. Prof. Burne’s research is carried out in close collaboration with Professors John McGrath and Darryl Eyles, in a multidisciplinary team. Together they have an integrated research program using a broad range of neuroscientific techniques to explore potential causes of schizophrenia. There is a particular focus on early life, nongenetic risk factors and the team has skills in epidemiology, psychiatry, neuroanatomy, molecular biology, developmental biology and behavioural neuroscience. The Burne group is currently developing animal models related to risk factors for schizophrenia and autism.

Availability

Professor Thomas Burne is:
Available for supervision
Media expert

Fields of research

Works

Search Professor Thomas Burne’s works on UQ eSpace

222 works between 1996 and 2024

161 - 180 of 222 works

2007

Journal Article

The impact of nonlinear exposure-risk relationships on seasonal time-series data: modelling Danish neonatal birth anthropometric data

McGrath, John, Barnett, Adrian, Eyles, Darryl, Burne, Thomas, Pedersen, Carsten B. and Mortensen, Preben Bo (2007). The impact of nonlinear exposure-risk relationships on seasonal time-series data: modelling Danish neonatal birth anthropometric data. BMC Medical Research Methodology, 7 (1) 45, Article Number: 45. doi: 10.1186/1471-2288-7-45

The impact of nonlinear exposure-risk relationships on seasonal time-series data: modelling Danish neonatal birth anthropometric data

2007

Journal Article

Maternal vitamin D depletion alters neurogenesis in the developing rat brain

Cui, X. Y., McGrath, J. J., Burne, T. H. J., Mackay-Sim, A. and Eyles, D. W. (2007). Maternal vitamin D depletion alters neurogenesis in the developing rat brain. International Journal of Developmental Neuroscience, 25 (4), 227-232. doi: 10.1016/j.ijdevneu.2007.03.006

Maternal vitamin D depletion alters neurogenesis in the developing rat brain

2007

Journal Article

No association between serum 25-Hydroxyvitamin D3 level and performance on psychometric tests in NHANes III

McGrath, J. J., Scragg, R., Chant, D. C., Eyles, D., Burne, T. H. J. and Obradovic, D. (2007). No association between serum 25-Hydroxyvitamin D3 level and performance on psychometric tests in NHANes III. Neuroepidemiology, 29 (1-2), 49-54. doi: 10.1159/000108918

No association between serum 25-Hydroxyvitamin D3 level and performance on psychometric tests in NHANes III

2007

Conference Publication

Developmental vitamin D deficiency, postnatal development and adult behaviour in Sprague-Dawley rats

Burne, T. H., O'Loan, J., Kesby, J., McGrath, J. J. and Eyles, D. W. (2007). Developmental vitamin D deficiency, postnatal development and adult behaviour in Sprague-Dawley rats. 10th International Congress on Schizophrenia Research, Savannah, GA, United States, 02-06 April 2005. Oxford, United Kingdom: Oxford University Press.

Developmental vitamin D deficiency, postnatal development and adult behaviour in Sprague-Dawley rats

2007

Conference Publication

Developmental vitamin D deficiency; A candidate risk factor for schizophrenia

Eyles, DW, Burne, T, Cui, X, Kesby, J, Ko, P and McGrath, J (2007). Developmental vitamin D deficiency; A candidate risk factor for schizophrenia. 10th International Congress on Schizophrenia Research, Savannah GA, APR 02-06, 2005. OXFORD: OXFORD UNIV PRESS.

Developmental vitamin D deficiency; A candidate risk factor for schizophrenia

2006

Journal Article

Olfactory Ability in the Healthy Population: Reassessing Presbyosmia

Mackay-Sim, Alan, Johnston, Amy N. B., Owen, Caroline and Burne, Thomas H. J. (2006). Olfactory Ability in the Healthy Population: Reassessing Presbyosmia. Chemical Senses, 31 (8), 763-771. doi: 10.1093/chemse/bjl019

Olfactory Ability in the Healthy Population: Reassessing Presbyosmia

2006

Conference Publication

Modeling cognitive deficits in schizophrenia using rodents

Burne, T. H. J. (2006). Modeling cognitive deficits in schizophrenia using rodents. OXFORD: BLACKWELL PUBLISHING.

Modeling cognitive deficits in schizophrenia using rodents

2006

Journal Article

Effect of Y1 receptor deficiency on motor activity, exploration and anxiety

Karl, Tim, Burne, Thomas H. J. and Herzog, Herbert (2006). Effect of Y1 receptor deficiency on motor activity, exploration and anxiety. Behavioural Brain Research, 167 (1), 87-93. doi: 10.1016/j.bbr.2005.08.019

Effect of Y1 receptor deficiency on motor activity, exploration and anxiety

2006

Journal Article

Swimming behaviour and post-swimming activity in Vitamin D receptor knockout mice

Burne, Thomas H. J., Johnston, Amy N. B., McGrath, John J. and Mackay-Sim, Alan (2006). Swimming behaviour and post-swimming activity in Vitamin D receptor knockout mice. Brain Research Bulletin, 69 (1), 74-78. doi: 10.1016/j.brainresbull.2005.10.014

Swimming behaviour and post-swimming activity in Vitamin D receptor knockout mice

2006

Conference Publication

From biological marker to endophenotype: the role of animal models

Eyles, D., Burne, T. and McGrath, J. (2006). From biological marker to endophenotype: the role of animal models. Brainwaves’ - The Australasian Society for Psychiatric Research Annual Meeting 2006, Sydney, Australia, 6-8 December 2006. doi: 10.1017/S0924270800032312

From biological marker to endophenotype: the role of animal models

2006

Journal Article

Hyperlocomotion associated with transient prenatal vitamin D deficiency is ameliorated by acute restraint

Burne, Thomas H.J., OLoan, Jonathon, McGrath, John J. and Eyles, Darryl W. (2006). Hyperlocomotion associated with transient prenatal vitamin D deficiency is ameliorated by acute restraint. Behavioural Brain Research, 174 (1), 119-124. doi: 10.1016/j.bbr.2006.07.015

Hyperlocomotion associated with transient prenatal vitamin D deficiency is ameliorated by acute restraint

2006

Conference Publication

The DVD animal model of schizophrenia: Early gestational hypovitaminosis D reduces neonatal brain GDNF

Eyles, D. W., O'Loan, J., Burne, T. H. J. and McGrath, J. (2006). The DVD animal model of schizophrenia: Early gestational hypovitaminosis D reduces neonatal brain GDNF. 13th Biennial Winter Workshop on Schizophrenia Research, Davos, Switzerland, 4-10 February, 2006. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/j.schres.2006.01.006

The DVD animal model of schizophrenia: Early gestational hypovitaminosis D reduces neonatal brain GDNF

2006

Book Chapter

Prenatal Vitamin D Deficiency and Brain Development

Burne, T. H. J., McGrath, J. J., MacKay-Sim, A. and Eyles, D. W. (2006). Prenatal Vitamin D Deficiency and Brain Development. Vitamin D: New Research. (pp. 153-172) edited by Veronica D. Stolzt. USA: Nova Science Publishers Inc.

Prenatal Vitamin D Deficiency and Brain Development

2006

Conference Publication

The DVD animal model of schizophrenia: Effects of low maternal vitamin D on brain dopamine

Eyles, D. W., Ko, P., Kesby, J. P., Burne, H. J. and McGrath, J. (2006). The DVD animal model of schizophrenia: Effects of low maternal vitamin D on brain dopamine. XIIIth Biennial Winter Workshop on Schizophrenia Research, Davos, Switzerland, 4-10 February 2006. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.schres.2006.01.006

The DVD animal model of schizophrenia: Effects of low maternal vitamin D on brain dopamine

2006

Journal Article

Developmental vitamin D (DVD) deficiency in the rat alters adult behaviour independently of HPA function

Eyles, D. W., Rogers, F., Buller, K., McGrath, J. J., Ko, P., French, K. and Burne, T. H. J. (2006). Developmental vitamin D (DVD) deficiency in the rat alters adult behaviour independently of HPA function. Psychoneuroendocrinology, 31 (8), 958-964. doi: 10.1016/j.psyneuen.2006.05.006

Developmental vitamin D (DVD) deficiency in the rat alters adult behaviour independently of HPA function

2006

Conference Publication

Developmental vitamin D Depletion alters adult rat behaviour and response to psychomimetic drugs: a relevant model for schizophrenia

Kesby, J. P., OLoan, J., Burne, T. H., McGrath, J. and Eyles, D. W. (2006). Developmental vitamin D Depletion alters adult rat behaviour and response to psychomimetic drugs: a relevant model for schizophrenia. Australasian Schizophrenia Conference, Fremantle, 21-23 August 2006. Abingdon, England: Informa Healthcare. doi: 10.1111/j.1440-1614.2006.01859_2.x

Developmental vitamin D Depletion alters adult rat behaviour and response to psychomimetic drugs: a relevant model for schizophrenia

2006

Conference Publication

Developmental vitamin D deficiency alters adult behaviour: An informative animal model of schizophrenia

Burne, T. H. J., Kesby, J., OLoan, J., McGrath, J. J., Mackay-Sim, A. and Eyles, D. W. (2006). Developmental vitamin D deficiency alters adult behaviour: An informative animal model of schizophrenia. XIIIth Biennial Winter Workshop on Schizophrenia Research, Davos, Switzerland, 4-10 February 2006. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.schres.2006.01.006

Developmental vitamin D deficiency alters adult behaviour: An informative animal model of schizophrenia

2005

Conference Publication

Adult stem cells from persons with Parkinson's disease are therapeutic in a rat model

Murrell, W, Donnellan, M, Wetzig, A, Burne, T, Silburn, P and Mackay-Sim, A (2005). Adult stem cells from persons with Parkinson's disease are therapeutic in a rat model. 18th World Congress of Neurology, Sydney Australia, Nov 05-11, 2005. AMSTERDAM: ELSEVIER SCIENCE BV.

Adult stem cells from persons with Parkinson's disease are therapeutic in a rat model

2005

Journal Article

Seasonal variation in birth weight

McGrath, John J., Burne, Thomas H. and Eyles, Darryl W. (2005). Seasonal variation in birth weight. Canadian Medical Association Journal, 173 (7), 733-733. doi: 10.1503/cmaj.1050100

Seasonal variation in birth weight

2005

Journal Article

Season of birth and risk of brain tumors in adults

Ko, P., Eyles, D., Burne, T., Mackay-Sim, A. and McGrath, J. J. (2005). Season of birth and risk of brain tumors in adults. Neurology, 64 (7), 1317-1317. doi: 10.1212/WNL.64.7.1317

Season of birth and risk of brain tumors in adults

Funding

Current funding

  • 2023 - 2025
    Lab based analysis of rodent blood and tissue in a rodent model of fetal growth restriction (FGR)
    CSIRO
    Open grant
  • 2023 - 2026
    Reverse translation of a rodent cognitive flexibility task
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2018
    A specialised surgical and behavioural facility for longitudinal, multimodal examination of the rodent brain
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016 - 2019
    Delayed radial glial maturation linked to NFI deficiency as an underlying cause of cortical defects in humans and mice
    NHMRC Project Grant
    Open grant
  • 2016
    Light-sheet microscope for high-speed 3D imaging of live organisms and fixed tissue
    NHMRC Equipment Grant
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015
    Reverse translation of cognitive tasks for animal models of neuropsychiatric disorders
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Adult vitamin D deficiency and cognitive dysfunction in a mouse model
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    The Developmental vitamin D-deficiency animal model of schizophrenia:- Critical window for intervention and optimal dose
    NHMRC Project Grant
    Open grant
  • 2014
    Touchscreen-automated cognitive testing for mice
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2016
    Early pharmacological intervention in an animal model of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Developmental vitamin D deficiency and prefrontal cortical dysfunction
    NHMRC Project Grant
    Open grant
  • 2011
    Advanced behavioural facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2014
    Attentional processing in developmentally vitamin D deficient rats: Modelling the cognitive symptoms of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Neonatal vitamin D status and risk of schizophrenia: a replication in two independent samples
    NHMRC Project Grant
    Open grant
  • 2010
    Zebrafish Aquarium - expand capacity of existing Zebrafish facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2011
    Zebrafish behavioural suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2012
    Advanced paternal age: behavioural, neuroanatomical and genomic correlates in the offspring of older fathers
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    The Developmental vitamin D model (DVD) as an animal model for schizophrenia
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Thomas Burne is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Measuring cognitive flexibility in rodents

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    The neural basis of predictive coding: Defining how the brain uses feedback to propagate predictions

    Associate Advisor

    Other advisors: Dr Clarissa Whitmire

Completed supervision

Media

Enquiries

Contact Professor Thomas Burne directly for media enquiries about:

  • Animal behaviour
  • Animal models
  • Behaviour in animals
  • Behavioural neuroscience
  • Behavioural phenotyping
  • Neuroscience - behavioural
  • Phenotyping - behavioural
  • Schizophrenia

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