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2018 Journal Article Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregates in vitroChakravarthy, Madhuri, AlShamaileh, Hadi, Huang, He, Tannenberg, Rudi K., Chen, Suxiang, Worrall, Simon, Dodd, Peter R. and Veedu, Rakesh N. (2018). Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregates in vitro. Chemical Communications, 54 (36), 4593-4596. doi: 10.1039/c8cc02256a |
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2018 Journal Article Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid deliveryKokil, Ganesh R., Veedu, Rakesh N., Le, Bao Tri, Ramm, Grant A. and Parekh, Harendra S. (2018). Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery. Scientific Reports, 8 (1) 4832, 4832. doi: 10.1038/s41598-018-22902-9 |
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2017 Journal Article Next generation nucleic acid aptamers with two base modified nucleotides improve the binding affinity and potencyNaduvile Veedu, Rakesh and Al Shamaileh, Hadi (2017). Next generation nucleic acid aptamers with two base modified nucleotides improve the binding affinity and potency. ChemBioChem, 18 (16), 1565-1567. doi: 10.1002/cbic.201700276 |
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2017 Journal Article Development of an efficient G-quadruplex stabilized thrombin binding aptamer containing 3-carbon spacer moleculeAaldering, Lukas J. , Poongavanam, Vasanthanathan , Murugan, N. Arul , Jørgensen, Per Trolle , Wengel, Jesper and Veedu, Rakesh N. (2017). Development of an efficient G-quadruplex stabilized thrombin binding aptamer containing 3-carbon spacer molecule. ChemBioChem, 18 (8), 755-763. doi: 10.1002/cbic.201600654 |
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2017 Journal Article Nucleic acid-based theranostics for tackling Alzheimer's diseaseChakravarthy, Madhuri, Chen, Suxiang, Dodd, Peter R. and Veedu, Rakesh N. (2017). Nucleic acid-based theranostics for tackling Alzheimer's disease. Theranostics, 7 (16) 21529, 3933-3947. doi: 10.7150/thno.21529 |
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2015 Journal Article Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibitionEdwards, Stacey L., Poongavanam, Vasanthanathan, Kanwar, Jagat R., Roy, Kislay, Hillman, Kristine M., Prasad, Neerati, Leth-Larsen, Rikke, Petersen, Michael, Marusic, Maja, Plavec, Janez, Wengel, Jesper and Veedu, Rakesh N. (2015). Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition. Chemical Communications, 51 (46), 9499-9502. doi: 10.1039/c5cc02756j |
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2015 Journal Article Comments on photochromism of 3-(3-pyridyl)sydnone and 4-alkenylsydnonesWentrup, Curt, Kvaskoff, David and Veedu, Rakesh N (2015). Comments on photochromism of 3-(3-pyridyl)sydnone and 4-alkenylsydnones. Journal of Photochemistry and Photobiology A: Chemistry, 298, 62-63. doi: 10.1016/j.jphotochem.2014.10.010 |
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2015 Journal Article Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeuticsKokil, Ganesh R., Veedu, Rakesh N., Ramm, Grant A., Prins, Johannes B. and Parekh, Harendra S. (2015). Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeutics. Chemical Reviews, 115 (11), 4719-4743. doi: 10.1021/cr5002832 |
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2015 Journal Article Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapyAaldering, Lukas J., Tayeb, Hossam, Krishnan, Shilpa, Fletcher, Susan, Wilton, Stephen D. and Veedu, Rakesh N. (2015). Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy. RNA Biology, 12 (4), 412-425. doi: 10.1080/15476286.2015.1017234 |
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2014 Journal Article Computational investigation of Locked Nucleic Acid (LNA) nucleotides in the active sites of DNA polymerases by molecular docking simulationsPoongavanam, Vasanthanathan, Madala, Praveen K., Højland, Torben and Veedu, Rakesh N. (2014). Computational investigation of Locked Nucleic Acid (LNA) nucleotides in the active sites of DNA polymerases by molecular docking simulations. PLoS One, 9 (7) e102126, 1-7. doi: 10.1371/journal.pone.0102126 |
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2014 Journal Article Quencher-free molecular beacons as probes for oligonucleotides containing CAG repeat sequencesKim K.T., Veedu R.N., Seo Y.J. and Kim B.H. (2014). Quencher-free molecular beacons as probes for oligonucleotides containing CAG repeat sequences. Chemical Communications, 50 (13), 1561-1563. doi: 10.1039/c3cc48853e |
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2013 Journal Article Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancersDawar, Swati, Singh, Neha, Kanwar, Rupinder K., Kennedy, Richard Lee, Veedu, Rakesh N., Zhou, Shu-Feng, Krishnakumar, Subramanian, Hazra, Sarbani, Sasidharan, Sreenivasan, Duan, Wei and Kanwar, Jagat R. (2013). Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancers. Drug Discovery Today, In Press, Corrected Proof (23-24), 1-9. doi: 10.1016/j.drudis.2013.09.009 |
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2013 Journal Article G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex foldMarušič, Maja, Veedu, Rakesh N., Wengel, Jesper and Plavec, Janez (2013). G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold. Nucleic Acids Research, Advance Access (20), 1-13. doi: 10.1093/nar/gkt697 |
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2013 Journal Article Nucleic acid aptamers as novel class of therapeutics to mitigate Alzheimer's disease pathologyTannenberg, Rudi K., Al Shamaileh, Hadi, Lauridsen, Lasse H., Kanwar, Jagat R., Dodd, Peter R. and Veedu, Rakesh N. (2013). Nucleic acid aptamers as novel class of therapeutics to mitigate Alzheimer's disease pathology. Current Alzheimer Research, 10 (4), 442-448. doi: 10.2174/1567205011310040009 |
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2013 Journal Article Synthesis of DNA Oligonucleotides containing C5-Ethynylbenzenesulfonamide-modified nucleotides (EBNA) by polymerases towards the construction of base functionalized nucleic acidsGoubet, Astrid, Chardon, Antoine, Kumar, Pawan, Sharma, Pawan K. and Veedu, Rakesh N. (2013). Synthesis of DNA Oligonucleotides containing C5-Ethynylbenzenesulfonamide-modified nucleotides (EBNA) by polymerases towards the construction of base functionalized nucleic acids. Bioorganic & Medicinal Chemistry Letters, 23 (3), 761-763. doi: 10.1016/j.bmcl.2012.11.096 |
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2013 Journal Article Targeted multimodal liposomes for nano-delivery and imaging: An avenger for drug resistance and cancerGurudevan, Sneha, Kanwar, Rupinder K., Veedu, Rakesh N., Sasidharan, Sreenivasan, Kennedy, Richard L., Walder, Ken, Prasad, Neerati and Kanwar, Jagat R. (2013). Targeted multimodal liposomes for nano-delivery and imaging: An avenger for drug resistance and cancer. Current Gene Therapy, 13 (5), 322-334. doi: 10.2174/156652321305131212123558 |
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2013 Journal Article Selenomethylene locked nucleic acid enables reversible hybridization in response to redox changesMorihiro, Kunihiko, Kodama, Tetsuya, Kentefu, Moai, Yoshihiro, Veedu, Rakesh N. and Obika, Satoshi (2013). Selenomethylene locked nucleic acid enables reversible hybridization in response to redox changes. Angewandte Chemie-International Edition, 52 (19), 5074-5078. doi: 10.1002/anie.201300555 |
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2013 Journal Article Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivoColes, Daniel J., Rolfe, Barbara E., Boase, Nathan R. B., Veedu, Rakesh N. and Thurecht, Kristofer J. (2013). Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo. Chemical Communications, 49 (37), 3836-3838. doi: 10.1039/c3cc00127j |
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2012 Journal Article Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerasesWheeler, Megan, Chardon, Antoine, Goubet, Astrid, Morihiro, Kunihiko, Tsan, Sze Yee, Edwards, Stacey L., Kodama, Tetsuya, Obika, Satoshi and Veedu, Rakesh N. (2012). Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases. Chemical Communications, 48 (89), 11020-11022. doi: 10.1039/C2CC36464F |
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2012 Journal Article Nucleic acid aptamers against biotoxins: a new paradigm toward the treatment and diagnostic approachLauridsen, Lasse Holm and Veedu, Rakesh N. (2012). Nucleic acid aptamers against biotoxins: a new paradigm toward the treatment and diagnostic approach. Nucleic Acid Therapeutics, 22 (6), 371-379. doi: 10.1089/nat.2012.0377 |
