Characterisation of monoaminergic transmission in Central Amygdala (2004-2006)

This project will identify the distribution and function of dopamine serotonin and noradrenalin receptors on the various cell types and their inputs in the medial lateral and capsular divisions of Central Amygdala (CeA). We will test for tonic endogenous activation of monoaminergic receptors and synaptic release from electrically stimulated fibers terminating in CeA. Using paired recordings and calcium imaging we will investigate intracellular mechanisms underlying monoamine receptor mediated effects. These findings when correlated with published behavioural studies will provide greater understanding of the role of the divisions of CeA and the inputs they receive in the function of the amygdala.