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2020

Conference Publication

Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy

Sheng, Yong H., Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh Y., He, Yaowu, Wu, Andy, Hooper, John, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira Z., McGuckin, Michael, Florin, Timothy H. and Begun, Jakob (2020). Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy. DDW 2020, Online, 2-5 May 2020. Philadelphia, PA United States: Elsevier . doi: 10.1016/s0016-5085(20)30856-8

Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy

2018

Conference Publication

Dual role of TLR4 in colorectal tumorigenesis in obesitymediated inflammation in vivo

Morata, Cynthia, Picon-Ruiz, Manuel, Davies, Julie, Qureshi, Rehana, Burgueno, Juan F., Abreu, Maria T. and Slingerland, Joyce (2018). Dual role of TLR4 in colorectal tumorigenesis in obesitymediated inflammation in vivo. In: , , (S-649-S-649). . doi:10.1016/s0016-5085(18)32311-4

Dual role of TLR4 in colorectal tumorigenesis in obesitymediated inflammation in vivo

2017

Conference Publication

TLR4-Driven Tumorigenesis is Associated with an Expansion of Intestinal Stem Cells

Burgueno, Juan F., Fernández, Irina, Diaz, Sophia, Phillips, Matthew C., Santander, Ana M., Davies, Julie, Santaolalla, Rebeca, Dheer, Rishu and Abreu, Maria T. (2017). TLR4-Driven Tumorigenesis is Associated with an Expansion of Intestinal Stem Cells. Digestive Disease Week (DDW) 2017, Chicago, IL United States, 6-9 May 2017. PHILADELPHIA: Elsevier BV. doi: 10.1016/s0016-5085(17)30440-7

TLR4-Driven Tumorigenesis is Associated with an Expansion of Intestinal Stem Cells

2017

Conference Publication

Genotoxic Effects of PCB 153 Cause NF-KB Dependent Increases in Intestinal Permeability and Intestinal Inflammation via the ATM/NEMO Pathway

Phillips, Matthew C., Dheer, Rishu, Santaolalla, Rebeca, Davies, Julie, Burgueno, Juan F., Lang, Jessica K., Toborek, Michal and Abreu, Maria T. (2017). Genotoxic Effects of PCB 153 Cause NF-KB Dependent Increases in Intestinal Permeability and Intestinal Inflammation via the ATM/NEMO Pathway. Digestive Disease Week (DDW) 2017, Chicago, IL United States, 6-9 May 2017. PHILADELPHIA: Elsevier. doi: 10.1016/s0016-5085(17)33272-9

Genotoxic Effects of PCB 153 Cause NF-KB Dependent Increases in Intestinal Permeability and Intestinal Inflammation via the ATM/NEMO Pathway

2017

Conference Publication

Characterization of Immune Phenotypes as Predictive Biomarkers for Response to Vedolizumab

Davies, Julie, Diaz, Sophia, Quintero, Maria A., Czul, Frank, Santaolalla, Rebeca, Dheer, Rishu, Burgueno, Juan F., Guevara, Patricia L., Opiela, Shannon J., Deshpande, Amar, Kerman, David H., Damas, Oriana M., Sundrud, Mark and Abreu, Maria T. (2017). Characterization of Immune Phenotypes as Predictive Biomarkers for Response to Vedolizumab. Digestive Disease Week (DDW) 2017, Chicago, IL United States, 6-9 May 2017. PHILADELPHIA: Elsevier. doi: 10.1016/s0016-5085(17)32170-4

Characterization of Immune Phenotypes as Predictive Biomarkers for Response to Vedolizumab

2016

Conference Publication

Analysis of the microbiome and metabolic pathways reveal differences between mucosa and lamina propria surfaces in IBD patients

Dheer, Rishu, Davies, Julie, Quintero, Maria A., Santaolalla, Rebeca, Deshpande, Amar, Kerman, David and Abreu, Maria T. (2016). Analysis of the microbiome and metabolic pathways reveal differences between mucosa and lamina propria surfaces in IBD patients. DDW 2016 Digestive Disease Week, San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(16)32009-1

Analysis of the microbiome and metabolic pathways reveal differences between mucosa and lamina propria surfaces in IBD patients

2016

Conference Publication

Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb Activation

Winkler, Ingrid G., Barbier, Valerie, Ward, Micheal, Tallack, Michael, Lowe, Jessica, Davies, Julie, Erbani, Johanna, Magnani, John L. and Levesque, Jean-Pierre (2016). Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb Activation. 58th Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.v128.22.2823.2823

Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb Activation

2016

Conference Publication

Mucosal Microbiota that Breach the Intestinal Epithelial Barrier-A Step Towards Identifying Potential Pathogens in IBD

Dheer, Rishu, Davies, Julie, Quintero, Maria Alejandra, Santaolalla, Rebeca, Deshpande, Amar, Kerman, David, McCauley, Jacob and Abreu, Maria (2016). Mucosal Microbiota that Breach the Intestinal Epithelial Barrier-A Step Towards Identifying Potential Pathogens in IBD. Advances in Inflammatory Bowel Diseases Crohn's and Colitis Foundation's National Clinical and Research Conference, Orlando, FL, United States, 10-12 December 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mib.0000480312.66811.0f

Mucosal Microbiota that Breach the Intestinal Epithelial Barrier-A Step Towards Identifying Potential Pathogens in IBD

2016

Conference Publication

Characterization of Primary Colonic Stem Cells in a Murine Model of Colitis-Associated Cancer

Diaz, Sophia, Davies, Julie, Santaolalla, Rebeca, Dheer, Rishu, Lang, Jessica, Phillips, Matthew and Abreu, Maria (2016). Characterization of Primary Colonic Stem Cells in a Murine Model of Colitis-Associated Cancer. Advances in Inflammatory Bowel Diseases Crohn's and Colitis Foundation's National Clinical and Research Conference, Orlando, FL, United States, 10-12 December 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mib.0000480299.71348.c9

Characterization of Primary Colonic Stem Cells in a Murine Model of Colitis-Associated Cancer

2016

Conference Publication

Inflammatory Effects of Polychlorinated Biphenyls: Effects on the Intestinal Epithelial Cells and Gut Microbiome

Phillips, Matthew, Dheer, Rishu, Santaolalla, Rebeca, Davies, Julie, Lang, Jessica and Abreu, Maria (2016). Inflammatory Effects of Polychlorinated Biphenyls: Effects on the Intestinal Epithelial Cells and Gut Microbiome. Advances in Inflammatory Bowel Diseases Crohn's and Colitis Foundation's National Clinical and Research Conference, Orlando, FL, United States, 10-12 December 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mib.0000480286.31409.ba

Inflammatory Effects of Polychlorinated Biphenyls: Effects on the Intestinal Epithelial Cells and Gut Microbiome

2016

Conference Publication

Inflammatory Effects of Polychlorinated Biphenyls: Effects on Intestinal Epithelial Cells and Gut Microbiome

Phillips, Matthew C., Dheer, Rishu, Davies, Julie, Santaolalla, Rebeca, Lang, Jessica K. and Abreu, Maria T. (2016). Inflammatory Effects of Polychlorinated Biphenyls: Effects on Intestinal Epithelial Cells and Gut Microbiome. Digestive Disease Week (DDW) 2016, San Diego, CA United States, 21 - 24 May 2016. PHILADELPHIA: Elsevier. doi: 10.1016/s0016-5085(16)31321-x

Inflammatory Effects of Polychlorinated Biphenyls: Effects on Intestinal Epithelial Cells and Gut Microbiome

2016

Conference Publication

A Translational Study Characterizing the T-cell Signatures of IBD Patients Responding to Vedolizumab, an α4β7 Integrin Blocker

Diaz, Sophia, Davies, Julie, Santaolalla, Rebeca, Dheer, Rishu, Quintero, Maria A., Deshpande, Amar, Kerman, David, Damas, Oriana M., Sundrud, Mark and Abreu, Maria T. (2016). A Translational Study Characterizing the T-cell Signatures of IBD Patients Responding to Vedolizumab, an α4β7 Integrin Blocker. Digestive Disease Week (DDW) 2016, San Diego, CA United States, 21 - 24 May 2016. PHILADELPHIA: Elsevier. doi: 10.1016/s0016-5085(16)30291-8

A Translational Study Characterizing the T-cell Signatures of IBD Patients Responding to Vedolizumab, an α4β7 Integrin Blocker

2016

Conference Publication

The Effects of Environmental Enrichment, Social Housing and Gender on Intestinal Tumorigenesis in a Murine Model of Colon Cancer

Lang, Jessica, Santaolalla, Rebeca, Dheer, Rishu, Davies, Julie, Phillips, Matthew, Grant, Jeff, Zaias, Julia and Abreu, Maria (2016). The Effects of Environmental Enrichment, Social Housing and Gender on Intestinal Tumorigenesis in a Murine Model of Colon Cancer. Advances in Inflammatory Bowel Diseases Crohn's and Colitis Foundation's National Clinical and Research Conference, Orlando, FL, United States, 10-12 December 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mib.0000480277.60118.38

The Effects of Environmental Enrichment, Social Housing and Gender on Intestinal Tumorigenesis in a Murine Model of Colon Cancer

2015

Conference Publication

Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade

Winkler, Ingrid G., Barbier, Valerie, Radford, Kristen J., Davies, Julie M., Levesque, Jean-Pierre, Smith, Theodore A. G., Fogler, William E. and Magnani, John L. (2015). Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade. 57th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 5-8 December 2015. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V126.23.512.512

Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade

2015

Conference Publication

Viral products elicit different phenotypes from small intestine and colonic crypt cultures

Davies, Julie M., Santaolalla, Rebeca, von Furstenberg, Richard J., Henning, Susan J. and Abreu, Maria T. (2015). Viral products elicit different phenotypes from small intestine and colonic crypt cultures. In: , , (S-723-S-723). . doi:10.1016/s0016-5085(15)32465-3

Viral products elicit different phenotypes from small intestine and colonic crypt cultures

2014

Conference Publication

Interleukin-1 receptor-associated kinases are key in TLR4-mediated activation of B-catenin

Santaolalla, Rebeca, Davies, Julie, Dheer, Rishu, Lang, Jessica and Abreu, Maria (2014). Interleukin-1 receptor-associated kinases are key in TLR4-mediated activation of B-catenin. 2014 Advances in Inflammatory Bowel Diseases Crohn's and Colitis Foundation's National Clinical and Research Conference, Orlando, FL, United States, 4-6 December 2014. New York, United States: Oxford University Press . doi: 10.1097/01.mib.0000456893.54364.1a

Interleukin-1 receptor-associated kinases are key in TLR4-mediated activation of B-catenin

2014

Conference Publication

TLR4 Overexpression in the Intestinal Epithelium Disturbs Microbial Segregation and Intestinal Homeostasis

Dheer, Rishu, Davies, Julie M., Santaolalla, Rebeca, Fukata, Masayuki, Lang, Jessica K. and Abreu, Maria T. (2014). TLR4 Overexpression in the Intestinal Epithelium Disturbs Microbial Segregation and Intestinal Homeostasis. Digestive Disease Week (DDW) 2014, Chicago, IL United States, May 2014. PHILADELPHIA: Elsevier. doi: 10.1016/s0016-5085(14)63042-0

TLR4 Overexpression in the Intestinal Epithelium Disturbs Microbial Segregation and Intestinal Homeostasis

2014

Conference Publication

Intestinal epithelium specific TLR4 over-expression causes transmissible colitis via microbial dysbiosis

Dheer, Rishu, Davies, Julie, Santaolalla, Rebeca, Lang, Jessica and Abreu, Maria (2014). Intestinal epithelium specific TLR4 over-expression causes transmissible colitis via microbial dysbiosis. In: 2014 Advances in Inflammatory Bowel Diseases Crohn's and Colitis Foundation's National Clinical and Research Conference, Orlando, FL, United States, (S15-S15). 4-6 December 2014. doi:10.1097/01.mib.0000456684.04031.60

Intestinal epithelium specific TLR4 over-expression causes transmissible colitis via microbial dysbiosis

2014

Conference Publication

Stool Phospholipids and the Microbiota: Using Mass Spectrometry and Microbial Profiling to Generate Disease-Specific Signatures

Davies, Julie M., Dheer, Rishu, Hua, Hong-Uyen, Martinez, Mitchell, Bhattacharya, Sanjoy K. and Abreu, Maria T. (2014). Stool Phospholipids and the Microbiota: Using Mass Spectrometry and Microbial Profiling to Generate Disease-Specific Signatures. Digestive Disease Week (DDW) 2014, Chicago, IL United States, May 2014. Elsevier. doi: 10.1016/s0016-5085(14)60498-4

Stool Phospholipids and the Microbiota: Using Mass Spectrometry and Microbial Profiling to Generate Disease-Specific Signatures

2014

Conference Publication

TLR Signaling Alters Growth and Differentiation of Colonoids: Evidence for Innate Immune Signaling in Stem Cell Biology

Davies, Julie M., Santaolalla, Rebeca and Abreu, Maria T. (2014). TLR Signaling Alters Growth and Differentiation of Colonoids: Evidence for Innate Immune Signaling in Stem Cell Biology. Digestive Disease Week (DDW) 2014, Chicago, IL United States, May 2014. PHILADELPHIA: Elsevier. doi: 10.1016/s0016-5085(14)61867-9

TLR Signaling Alters Growth and Differentiation of Colonoids: Evidence for Innate Immune Signaling in Stem Cell Biology