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2024

Journal Article

Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans

Hahn, Anne, Hung, Grace Ching Ching, Ahier, Arnaud, Dai, Chuan-Yang, Kirmes, Ina, Forde, Brian M., Campbell, Daniel, Lee, Rachel Shin Yie, Sucic, Josiah, Onraet, Tessa and Zuryn, Steven (2024). Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans. Cell Metabolism. doi: 10.1016/j.cmet.2024.07.020

Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans

2023

Journal Article

ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription

Dai, Chuan-Yang, Ng, Chai Chee, Hung, Grace Ching Ching, Kirmes, Ina, Hughes, Laetitia A., Du, Yunguang, Brosnan, Christopher A., Ahier, Arnaud, Hahn, Anne, Haynes, Cole M., Rackham, Oliver, Filipovska, Aleksandra and Zuryn, Steven (2023). ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nature Cell Biology, 25 (8), 1-10. doi: 10.1038/s41556-023-01192-y

ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription

2022

Journal Article

LONP-1 aids propagation of deleterious mtDNA

Kirmes, Ina and Zuryn, Steven (2022). LONP-1 aids propagation of deleterious mtDNA. Nature Cell Biology, 24 (2), 127-128. doi: 10.1038/s41556-021-00838-z

LONP-1 aids propagation of deleterious mtDNA

2021

Journal Article

Doxorubicin induces wide-spread transcriptional changes in the myocardium of hearts distinguishing between mice with preserved and impaired cardiac function

Stamm, Paul, Kirmes, Ina, Palmer, Alexander, Molitor, Michael, Kvandova, Miroslava, Kalinovic, Sanela, Mihalikova, Dominika, Reid, George, Wenzel, Philip, Münzel, Thomas, Daiber, Andreas and Jansen, Thomas (2021). Doxorubicin induces wide-spread transcriptional changes in the myocardium of hearts distinguishing between mice with preserved and impaired cardiac function. Life Sciences, 284 119879, 119879. doi: 10.1016/j.lfs.2021.119879

Doxorubicin induces wide-spread transcriptional changes in the myocardium of hearts distinguishing between mice with preserved and impaired cardiac function

2021

Journal Article

PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome

Ahier, Arnaud, Dai, Chuan-Yang, Kirmes, Ina, Cummins, Nadia, Hung, Grace Ching Ching, Götz, Jürgen and Zuryn, Steven (2021). PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome. Cell Reports, 35 (9) 109203, 109203. doi: 10.1016/j.celrep.2021.109203

PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome

2018

Journal Article

Publisher Correction: affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism

Ahier, Arnaud, Dai, Chuan-Yang, Tweedie, Andrea, Bezawork-Geleta, Ayenachew, Kirmes, Ina and Zuryn, Steven (2018). Publisher Correction: affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism. Nature cell biology, 20 (3), 361-361. doi: 10.1038/s41556-018-0055-x

Publisher Correction: affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism

2018

Journal Article

Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism

Ahier, Arnaud, Dai, Chuan-Yang, Tweedie, Andrea, Bezawork-Geleta, Ayenachew, Kirmes, Ina and Zuryn, Steven (2018). Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism. Nature Cell Biology, 20 (3), 352-360. doi: 10.1038/s41556-017-0023-x

Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism

2015

Journal Article

A transient ischemic environment induces reversible compaction of chromatin

Kirmes, Ina, Szczurek, Aleksander, Prakash, Kirti, Charapitsa, Iryna, Heiser, Christina, Musheev, Michael, Schock, Florian, Fornalczyk, Karolina, Ma, Dongyu, Birk, Udo, Cremer, Christoph and Reid, George (2015). A transient ischemic environment induces reversible compaction of chromatin. Genome Biology, 16 (1) 246. doi: 10.1186/s13059-015-0802-2

A transient ischemic environment induces reversible compaction of chromatin