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2012

Journal Article

Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

Cohen, Jeffrey A., Coles, Alasdair J., Arnold, Douglas L., Confavreux, Christian, Fox, Edward J., Hartung, Hans-Peter, Havrdova, Eva, Selmaj, Krzysztof W., Weiner, Howard L., Fisher, Elizabeth, Brinar, Vesna V., Giovannoni, Gavin, Stojanovic, Miroslav, Ertik, Bella I., Lake, Stephen L., Margolin, David H., Panzara, Michael A., Compston, D. Alastair S., CARE-MS I investigators and McCombe, Pamela (2012). Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial. Lancet, 380 (9856), 1819-1828. doi: 10.1016/S0140-6736(12)61769-3

Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

2012

Journal Article

The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice

Ngo, S. T., Baumann, F., Ridall, P. G., Pettitt, A. N., Henderson, R. D., Bellingham, M. C. and McCombe, P. A. (2012). The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice. Clinical Neurophysiology, 123 (10), 2080-2091. doi: 10.1016/j.clinph.2012.01.028

The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice

2012

Journal Article

Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset

Baumann, F., Henderson, R. D., Ridall, P. Gareth, Pettitt, A. N. and McCombe, Pamela A. (2012). Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset. Clinical Neurophysiology, 123 (10), 2092-2098. doi: 10.1016/j.clinph.2012.03.007

Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset

2012

Journal Article

The role of epigenetic mechanisms and processes in autoimmune disorders

Greer, Judith M. and McCombe, Pamela A. (2012). The role of epigenetic mechanisms and processes in autoimmune disorders. Biologics: Targets and Therapy, 6, 307-327. doi: 10.2147/BTT.S24067

The role of epigenetic mechanisms and processes in autoimmune disorders

2012

Journal Article

Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis

Lin, C. Y., Pfluger, C. M., Henderson, R. D. and McCombe, P. A. (2012). Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis. Journal of Neuroimmunology, 249 (1-2), 93-95. doi: 10.1016/j.jneuroim.2012.05.001

Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis

2012

Journal Article

Structural hemispheric asymmetries in the human precentral gyrus hand representation

Rose, S., Rowland, T., Pannek, K., Baumann, F., Coulthard, A., McCombe, P. and Henderson, R. (2012). Structural hemispheric asymmetries in the human precentral gyrus hand representation. Neuroscience, 210, 211-221. doi: 10.1016/j.neuroscience.2012.02.044

Structural hemispheric asymmetries in the human precentral gyrus hand representation

2012

Journal Article

Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability

Yan, Jun, Greer, Judith M. and McCombe, Pamela A. (2012). Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability. Journal of Neuroimmunology, 246 (1-2), 78-84. doi: 10.1016/j.jneuroim.2012.02.013

Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability

2012

Journal Article

Frequency and function of regulatory T cells after ischaemic stroke in humans

Yan, Jun, Read, Stephen J., Henderson, Robert D., Hull, Renee, O'Sullivan, John D., McCombe, Pamela A. and Greer, Judith M. (2012). Frequency and function of regulatory T cells after ischaemic stroke in humans. Journal of Neuroimmunology, 243 (1-2), 89-94. doi: 10.1016/j.jneuroim.2011.12.019

Frequency and function of regulatory T cells after ischaemic stroke in humans

2012

Journal Article

Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study

Rose, Stephen, Pannek, Kerstin, Bell, Christopher, Baumann, Fusun, Hutchinson, Nicole, Coulthard, Alan, McCombe, Pamela and Henderson, Robert (2012). Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study. NeuroImage, 59 (3), 2661-2669. doi: 10.1016/j.neuroimage.2011.08.054

Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study

2012

Journal Article

Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis

Steyn, F. J., Ngo, S. T, Lee, J. D., Leong, J. W., Buckley, A. J., Veldhuis, J. D., McCombe, P. A., Chen, C. and Bellingham, M. C. (2012). Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology, 153 (8), 3735-3746. doi: 10.1210/en.2011-2171

Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis

2012

Journal Article

Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis

Yan, Jun, Liu, Jia, Lin, Clement Yihao, Australia and New Zealand Multiple Sclerorsis Genetics Consortium, Csurhes, Peter A., Pender, Michael P., McCombe, Pamela A. and Greer, Judith M. (2012). Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis. International Journal of Molecular Sciences, 13 (10), 13667-13679. doi: 10.3390/ijms131013667

Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis

2011

Journal Article

Use and monitoring of low dose rituximab in myasthenia gravis

Blum, Stefan, Gillis, David, Brown, Helen, Boyle, Richard, Henderson, Robert, Heyworth-Smith, David, Hogan, Patrick, Kubler, Paul, Lander, Cecilie, Limberg, Nicole, Pillans, Peter, Prain, Kerri, Staples, Christopher, Walsh, Michael, McCombe, Pamela and Wong, Richard (2011). Use and monitoring of low dose rituximab in myasthenia gravis. Journal of Neurology, Neurosurgery and Psychiatry, 82 (6), 659-663. doi: 10.1136/jnnp.2010.220475

Use and monitoring of low dose rituximab in myasthenia gravis

2011

Journal Article

Guillain-Barré Syndrome: Modern theories of etiology

Hardy, Todd A., Blum, Stefan, McCombe, Pamela A. and Reddel, Stephen W. (2011). Guillain-Barré Syndrome: Modern theories of etiology. Current Allergy and Asthma Reports, 11 (3), 197-204. doi: 10.1007/s11882-011-0190-y

Guillain-Barré Syndrome: Modern theories of etiology

2011

Journal Article

Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms

Greer, Judith M. and McCombe, Pamela A. (2011). Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms. Journal of Neuroimmunology, 234 (1-2), 7-18. doi: 10.1016/j.jneuroim.2011.03.003

Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms

2011

Journal Article

Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke

Singh, P., Yan, J., Hull, R., Read, S., O'Sullivan, J., Henderson, R.D., Rose, S., Greer, J.M. and McCombe, P.A. (2011). Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke. Journal of the Neurological Sciences, 304 (1-2), 117-121. doi: 10.1016/j.jns.2011.01.025

Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke

2011

Journal Article

The role of immune and inflammatory mechanisms in ALS

McCombe, P. A. and Henderson, R. D. (2011). The role of immune and inflammatory mechanisms in ALS. Current Molecular Medicine, 11 (3), 246-254. doi: 10.2174/156652411795243450

The role of immune and inflammatory mechanisms in ALS

2011

Journal Article

Atypical clinical presentations of the A3243G mutation, usually associated with MELAS

Blum, S., Robertson, T., Klingberg, S., Henderson, R.D. and McCombe, P. (2011). Atypical clinical presentations of the A3243G mutation, usually associated with MELAS. Internal Medicine Journal, 41 (2), 200-202. doi: 10.1111/j.1445-5994.2010.02379.x

Atypical clinical presentations of the A3243G mutation, usually associated with MELAS

2010

Journal Article

Effects of gender in amyotrophic lateral sclerosis

McCombe, PA and Henderson, RD (2010). Effects of gender in amyotrophic lateral sclerosis. Gender Medicine, 7 (6), 557-570. doi: 10.1016/j.genm.2010.11.010

Effects of gender in amyotrophic lateral sclerosis

2010

Journal Article

Biomarkers of disease in a case of familial lower motor neuron ALS

Baumann, Fusun, Rose, Stephen E., Nicholson, Garth A., Hutchinson, Nicole, Pannek, Kerstin, Pettitt, Anthony, McCombe, Pamela A. and Henderson, Robert D. (2010). Biomarkers of disease in a case of familial lower motor neuron ALS. Amyotrophic Lateral Sclerosis, 11 (5), 486-489. doi: 10.3109/17482961003774428

Biomarkers of disease in a case of familial lower motor neuron ALS

2010

Journal Article

Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves

Baumann, Fusun, Henderson, Robert D., Tremayne, Fred, Hutchinson, Nicole and McCombe, Pamela A. (2010). Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves. Muscle & Nerve, 41 (6), 785-793. doi: 10.1002/mus.21604

Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves