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2022 Journal Article PD-L1-targeted co-delivery of two chemotherapeutics for efficient suppression of skin cancer growthMovahedi, Fatemeh, Liu, Jie, Sun, Bing, Cao, Pei, Sun, Luyao, Howard, Christopher, Gu, Wenyi and Xu, Zhi Ping (2022). PD-L1-targeted co-delivery of two chemotherapeutics for efficient suppression of skin cancer growth. Pharmaceutics, 14 (7) 1488, 1488. doi: 10.3390/pharmaceutics14071488 |
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2022 Journal Article A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responsesAgrez, Michael, Rzepecka, Justyna, Turner, Darryl, Knox, Gavin, Chandler, Christopher, Howard, Christopher B., Fletcher, Nicholas, Thurecht, Kristofer, Parker, Stephen, Gooding, Hayley and Gallagher, Laura (2022). A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses. Scientific Reports, 12 (1) 11185, 11185. doi: 10.1038/s41598-022-15455-5 |
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2022 Journal Article Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted deliveryGao, Zhiliang, Li, Xiaoyu, Zhao, Kaijie, Geng, Huimin, Zhang, Peiyu, Ju, Yi, Huda, Pie, Howard, Christopher B, Thurecht, Kristofer J, Ashokkumar, Muthupandian, Hao, Jingcheng and Cui, Jiwei (2022). Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted delivery. Chemical Communications, 58 (56), 7777-7780. doi: 10.1039/d2cc01874h |
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2022 Journal Article An in vivo gene amplification system for high level expression in Saccharomyces cerevisiaePeng, Bingyin, Esquirol, Lygie, Lu, Zeyu, Shen, Qianyi, Cheah, Li Chen, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae. Nature Communications, 13 (1) 2895, 2895. doi: 10.1038/s41467-022-30529-8 |
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2022 Journal Article Antibody-based formats to target glioblastoma: overcoming barriers to protein drug deliveryGhosh, Saikat, Huda, Pie, Fletcher, Nicholas L., Howard, Christopher B., Walsh, Bradley, Campbell, Douglas, Pinkham, Mark B. and Thurecht, Kristofer J. (2022). Antibody-based formats to target glioblastoma: overcoming barriers to protein drug delivery. Molecular Pharmaceutics, 19 (5), 1233-1247. doi: 10.1021/acs.molpharmaceut.1c00996 |
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2022 Journal Article Recent advances in the production of recombinant factor IX: bioprocessing and cell engineeringBeauglehole, Aiden C, Roche Recinos, Dinora, Pegg, Cassandra L, Lee, Yih Yean, Turnbull, Victor, Herrmann, Susann, Marcellin, Esteban, Howard, Christopher B and Schulz, Benjamin L (2022). Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering. Critical Reviews in Biotechnology, 43 (3), 1-19. doi: 10.1080/07388551.2022.2036691 |
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2022 Journal Article Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruptionJanowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416 |
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2022 Journal Article Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics NeogenesisKenny, Sophie E., Antaw, Fiach, Locke, Warwick J., Howard, Christopher B., Korbie, Darren and Trau, Matt (2022). Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis. Life, 12 (3) 363, 1-24. doi: 10.3390/life12030363 |
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2022 Journal Article Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiaePeng, Bingyin, Bandari, Naga Chandra, Lu, Zeyu, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae. Communications Biology, 5 (1) 135, 135. doi: 10.1038/s42003-022-03070-z |
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2021 Journal Article Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detectionFarokhinejad, Fahimeh, Lane, Rebecca E., Lobb, Richard J., Edwardraja, Selvakumar, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2021). Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection. ACS Biomaterials Science and Engineering, 7 (12) acsbiomaterials.1c01001, 5850-5860. doi: 10.1021/acsbiomaterials.1c01001 |
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2021 Journal Article Amplification-free SARS-CoV-2 detection using nanoyeast-scFv and ultrasensitive plasmonic nanobox-integrated nanomixing microassayLi, Junrong, Wuethrich, Alain, Edwardraja, Selvakumar, Lobb, Richard J., Puttick, Simon, Rose, Stephen, Howard, Christopher B. and Trau, Matt (2021). Amplification-free SARS-CoV-2 detection using nanoyeast-scFv and ultrasensitive plasmonic nanobox-integrated nanomixing microassay. Analytical Chemistry, 93 (29) acs.analchem.1c01657, 10251-10260. doi: 10.1021/acs.analchem.1c01657 |
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2021 Journal Article Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified productZacchi, Lucia F., Roche-Recinos, Dinora, Pegg, Cassandra L., Phung, Toan K., Napoli, Mark, Aitken, Campbell, Sandford, Vanessa, Mahler, Stephen M., Lee, Yih Yean, Schulz, Benjamin L. and Howard, Christopher B. (2021). Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product. Communications Biology, 4 (1) 390, 390. doi: 10.1038/s42003-021-01903-x |
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2021 Journal Article Incorporation of unnatural amino acid into antibody fragment for creating a stable antibody-drug conjugateWardiana, Andri, Jones, Martina L., Mahler, Stephen M. and Howard, Christopher B. (2021). Incorporation of unnatural amino acid into antibody fragment for creating a stable antibody-drug conjugate. Indonesian Journal of Pharmacy, 32 (1), 96-105. doi: 10.22146/ijp.1101 |
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2021 Journal Article Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applicationsMacDonald, Michael A., Nöbel, Matthias, Roche Recinos, Dinora, Martínez, Verónica S., Schulz, Benjamin L., Howard, Christopher B., Baker, Kym, Shave, Evan, Lee, Yih Yean, Marcellin, Esteban, Mahler, Stephen, Nielsen, Lars Keld and Munro, Trent (2021). Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications. Critical Reviews in Biotechnology, 42 (7), 1-17. doi: 10.1080/07388551.2021.1998821 |
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2020 Journal Article A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cellsLund, Maria E., Howard, Christopher B., Thurecht, Kristofer J., Campbell, Douglas H., Mahler, Stephen M. and Walsh, Bradley J. (2020). A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells. BMC Cancer, 20 (1) 1214, 1214. doi: 10.1186/s12885-020-07562-1 |
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2020 Journal Article Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acidsSivaram, Amal J., Wardiana, Andri, Preethi, S. S. Hema, Fuchs, Adrian V., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2020). Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids. Macromolecular Rapid Communications, 41 (21) 2000294, e2000294. doi: 10.1002/marc.202000294 |
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2020 Journal Article Controlling the biological fate of micellar nanoparticles: balancing stealth and targetingSivaram, Amal J., Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Howard, Christopher B., Mahler, Stephen M., Alexander, Cameron, Kent, Stephen J., Bell, Craig A. and Thurecht, Kristofer J. (2020). Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting. ACS Nano, 14 (10) acsnano.0c06033, 13739-13753. doi: 10.1021/acsnano.0c06033 |
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2020 Journal Article Targeting the undruggable: emerging technologies in antibody delivery against intracellular targetsNiamsuphap, Suchada, Fercher, Christian, Kumble, Sumukh, Huda, Pie, Mahler, Stephen M. and Howard, Christopher B. (2020). Targeting the undruggable: emerging technologies in antibody delivery against intracellular targets. Expert Opinion on Drug Delivery, 17 (9), 1189-1211. doi: 10.1080/17425247.2020.1781088 |
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2020 Journal Article Identification of novel glycosylation events on human serum-derived factor IXPegg, Cassandra L., Zacchi, Lucia F., Recinos, Dinora Roche, Howard, Christopher B. and Schulz, Benjamin L. (2020). Identification of novel glycosylation events on human serum-derived factor IX. Glycoconjugate Journal, 37 (4), 471-483. doi: 10.1007/s10719-020-09922-2 |
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2020 Journal Article Glycoproteomic measurement of site-specific polysialylationPelingon, Ruby, Pegg, Cassandra L., Zacchi, Lucia F., Phung, Toan K., Howard, Christopher B., Xu, Ping, Hardy, Matthew P., Owczarek, Catherine M. and Schulz, Benjamin L. (2020). Glycoproteomic measurement of site-specific polysialylation. Analytical Biochemistry, 596 113625, 113625. doi: 10.1016/j.ab.2020.113625 |
