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2020

Journal Article

Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury

Wang, Haolu, Burke, Leslie J., Patel, Jatin, Tse, Brian W.C., Bridle, Kim R., Cogger, Victoria C., Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H. G., Roberts, Michael S., Gao, Wenchao and Liang, Xiaowen (2020). Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury. Theranostics, 10 (15), 6715-6727. doi: 10.7150/thno.44900

Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury

2019

Journal Article

Immune checkpoint blockade therapies for HCC: current status and future implications

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2019). Immune checkpoint blockade therapies for HCC: current status and future implications. Hepatoma Research, 2019 (5) 32. doi: 10.20517/2394-5079.2019.24

Immune checkpoint blockade therapies for HCC: current status and future implications

2019

Journal Article

Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury

Núñez, Kelley G., Frank, Anderson, Gonzalez-Rosario, Janet, Galliano, Gretchen, Bridle, Kim, Crawford, Darrell, Seal, John, Abbruscato, Frank, Vashistha, Himanshu, Thevenot, Paul T. and Cohen, Ari J. (2019). Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury. PLoS One, 14 (4) e0216242, e0216242. doi: 10.1371/journal.pone.0216242

Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury

2019

Journal Article

Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma

Huang, I-Tao, Dhungel, Bijay, Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G., Jayachandran, Aparna and Steel, Jason C (2019). Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma. Expert Opinion on Investigational Drugs, 28 (1), 7-18. doi: 10.1080/13543784.2019.1551359

Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma

2018

Journal Article

Exosome-based liquid biopsy in the management of hepatocellular carcinoma

Jayachandran, Aparna, Manda, Sasidhar Venkata, Shrestha, Ritu, Bridle, Kim R., Prithviraj, Prashanth and Crawford, Darrell H. G. (2018). Exosome-based liquid biopsy in the management of hepatocellular carcinoma. Hepatoma Research, 4 (8) 44, 44. doi: 10.20517/2394-5079.2018.59

Exosome-based liquid biopsy in the management of hepatocellular carcinoma

2018

Journal Article

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

Shrestha, Ritu, Prithviraj, Prashanth, Anaka, Matthew, Bridle, Kim R., Crawford, Darrell H. G., Dhungel, Bijay, Steel, Jason C. and Jayachandran, Aparna (2018). Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma. Frontiers in Oncology, 8 (JUL) 269, 269. doi: 10.3389/fonc.2018.00269

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

2018

Journal Article

Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease

Britton, Laurence, Bridle, Kim, Reiling, Janske, Santrampurwala, Nishreen, Wockner, Leesa, Ching, Helena, Stuart, Katherine, Subramaniam, V Nathan, Jeffrey, Gary, St Pierre, Tim, House, Michael, Gummer, Joel, Trengove, Robert, Olynyk, John, Crawford, Darrell and Adams, Leon (2018). Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease. Hepatology Communications, 2 (6), 644-653. doi: 10.1002/hep4.1190

Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease

2018

Journal Article

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

Britton, Laurence, Jaskowski, Lesley-Anne, Bridle, Kim, Secondes, Eriza, Wallace, Daniel, Santrampurwala, Nishreen, Reiling, Janske, Miller, Gregory, Mangiafico, Salvatore, Andrikopoulos, Sofianos, Subramaniam, V. Nathan and Crawford, Darrell (2018). Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet. CMGH, 5 (3), 319-331. doi: 10.1016/j.jcmgh.2018.01.005

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

2018

Journal Article

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

Britton, L. J., Bridle, Kim, Jaskowski, Lesley-Anne, He, Jingjing, Ng, Choaping, Ruelcke, Jayde E., Mohamed, Ahmed, Reiling, Janske, Santrampurwala, Nishreen, Hill, Michelle M., Whitehead, Jonathan P., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2018). Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes. Cellular and Molecular Gastroenterology and Hepatology, 6 (2), 214-217. doi: 10.1016/j.jcmgh.2018.04.005

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

2017

Journal Article

The Implications of the Shift Toward Donation After Circulatory Death in Australia

Reiling, Janske, Forrest, Elizabeth, Bridle, Kim R., Britton, Laurence J., Santrampurwala, Nishreen, Crawford, Darrell H. G., Dejong, Cornelis H. C. and Fawcett, Jonathan (2017). The Implications of the Shift Toward Donation After Circulatory Death in Australia. Transplantation Direct, 3 (12) e226, 1-7. doi: 10.1097/TXD.0000000000000743

The Implications of the Shift Toward Donation After Circulatory Death in Australia

2017

Journal Article

The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model

Reiling, J., Bridle, K. R., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Jansen, P. L. M., Damink, S. W. M. O., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2017). The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model. Biochimica et Biophysica Acta, 1864 (4 Pt B), 1284-1292. doi: 10.1016/j.bbadis.2017.06.028

The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model

2017

Journal Article

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

Heritage, Mandy, Jaskowski, Lesley, Bridle, Kim, Campbell, Catherine, Briskey, David, Britton, Laurence, Fletcher, Linda, Vitetta, Luis, Subramaniam, V. Nathan and Crawford, Darrell (2017). Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. World Journal of Gastrointestinal Pathophysiology, 8 (2), 67-76. doi: 10.4291/wjgp.v8.i2.67

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

2017

Journal Article

Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury

Wang, Haolu, Zhang, Run, Bridle, Kim R., Jayachandran, Aparna, Thomas, James A., Zhang, Wenzhu, Yuan, Jingli, Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific Reports, 7 (1) 45374. doi: 10.1038/srep45374

Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury

2017

Journal Article

Contribution of liver nonparenchymal cells to hepatic fibrosis: interactions with the local microenvironment

Fausther, Michel, Pritchard, Michele T., Popov, Yury V. and Bridle, Kim (2017). Contribution of liver nonparenchymal cells to hepatic fibrosis: interactions with the local microenvironment. Biomed Research International, 2017 6824762, 6824762-4. doi: 10.1155/2017/6824762

Contribution of liver nonparenchymal cells to hepatic fibrosis: interactions with the local microenvironment

2017

Journal Article

Low-dose lipopolysaccharide causes biliary injury by blood biliary barrier impairment in a rat hepatic ischemia/reperfusion model

Reiling, Janske, Bridle, Kim R., Gijbels, Marion, Schaap, Frank G., Jaskowski, Lesley, Santrampurwala, Nishreen, Britton, Laurence J., Campbell, Catherine M., Olde Damink, Steven W. M., Crawford, Darrell H. G., Dejong, Cornelius H. C. and Fawcett, Jonathan (2017). Low-dose lipopolysaccharide causes biliary injury by blood biliary barrier impairment in a rat hepatic ischemia/reperfusion model. Liver Transplantation, 23 (2), 194-206. doi: 10.1002/lt.24681

Low-dose lipopolysaccharide causes biliary injury by blood biliary barrier impairment in a rat hepatic ischemia/reperfusion model

2016

Journal Article

Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet

Britton, Laurence, Jaskowski, Lesley, Bridle, Kim, Santrampurwala, Nishreen, Reiling, Janske, Musgrave, Nick, Subramaniam, V. Nathan and Crawford, Darrell (2016). Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. Physiological Reports, 4 (12) e12837, e12837. doi: 10.14814/phy2.12837

Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet

2015

Journal Article

Urea production during Normothermic Machine Perfusion: Price of Success?

Reiling, Janske, Lockwood, David S. R., Simpson, Andrew H., Campbell, Catherine M., Bridle, Kim R., Santrampurwala, Nishreen, Britton, Laurence J., Crawford, Darrell Henry G., Dejong, Cornelius H. C. and Fawcett, Jonathan (2015). Urea production during Normothermic Machine Perfusion: Price of Success?. Liver Transplantation, 21 (5), 700-703. doi: 10.1002/lt.24094

Urea production during Normothermic Machine Perfusion: Price of Success?

2015

Journal Article

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

Bridle, Kim R., Sobbe, Amy L., de Guzman, C. Erika, Santrampurwala, Nishreen, Jaskowski, Lesley A., Clouston, Andrew D., Campbell, Catherine M., Nathan Subramaniam, V. and Crawford, Darrell H. G. (2015). Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice. Liver International, 35 (4), 1451-1463. doi: 10.1111/liv.12494

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

2015

Journal Article

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

Sobbe, Amy, Bridle, Kim R., Jaskowski, Lesley, de Guzman, C. Erika, Santrampurwala, Nishreen, Clouston, Andrew D., Campbell, Catherine M., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2015). Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox. Journal of Gastroenterology and Hepatology, 30 (3), 638-645. doi: 10.1111/jgh.12720

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

2015

Journal Article

Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging

Wang, Haolu, Liang, Xiaowen, Mohammed, Yousuf H., Thomas, James A., Bridle, Kim R., Thorling, Camilla A., Grice, Jeffrey E., Xu, Zhi Ping, Liu, Xin, Crawford, Darrell H. G. and Roberts, Michael S. (2015). Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging. Biomedical Optics Express, 6 (3), 780-792. doi: 10.1364/BOE.6.000780

Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging