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2013 Conference Publication Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat dietBritton, L., Jaskowski, L., Wilkinson, A., Bridle, K., Subramaniam, N. and Crawford, D. (2013). Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365 |
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2013 Conference Publication Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron HomeostasisSobbe, Amy, Frazer, David, Bridle, Kim, Jaskowski, Lesley, Ostini, Lesa, de Guzman, Erika, Santrampurwala, Nishreen, Anderson, Gregory, Subramaniam, V. Nathan and Crawford, Darrell (2013). Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453 |
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2013 Journal Article Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injuryTan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Subramaniam,V. Nathan, Clouston, Andrew D., Crane, Denis I., Bridle, Kim R., Anderson, Gregory J. and Fletcher, Linda M. (2013). Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury. Laboratory Investigation, 93 (12), 1295-1312. doi: 10.1038/labinvest.2013.121 |
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2013 Conference Publication Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injurySobbe, A. L., Frazer, D. M., Bridle, K. R., Jaskowski, L. A., Anderson, G. J., Subramaniam, V. N. and Crawford, D. H. (2013). Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365 |
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2013 Conference Publication Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat DietBritton, Laurence, Jaskowski, Lesley, Wilkinson, Ashley, Bridle, Kim, Subramaniam, Nathan and Crawford, Darrell (2013). Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453 |
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2012 Conference Publication Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLDWilkinson, Ashley S., Heritage, Mandy L., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Clouston, Andrew, Bridle, Kim, Macdonald, Graeme A., Anderson, Gregory, Fletcher, Linda M., Subramaniam, Nathan and Crawford, Darrell H. (2012). Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x |
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2012 Conference Publication Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- miceSobbe, Amy, Bridle, Kim, de Guzman, Cloe Erika, Santrampurwala, Nishreen, Subramaniam, Nathan and Crawford, Darrell H. (2012). Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x |
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2012 Conference Publication The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin EHeritage, Mandy L., Wilkinson, Ashley S., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Bridle, Kim, Clouston, Andrew, Anderson, Gregory, Fletcher, Linda M., Macdonald, Graeme A., Subramaniam, Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. Abstracts of the Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251.x |
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2012 Conference Publication The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin EHeritage, Mandy, Jaskowski, Lesley, Wilkinson, Ashley S., Britton, Laurence, Tan, Terrence C., Clouston, Andrew D., Bridle, Kim, Anderson, Gregory J., Macdonald, Graeme A., Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston MA., United States, 9-13 November 2012. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/hep.26040 |
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2011 Conference Publication Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolismSobbe, A. L., Bridle, K. R., Jaskowski, L. A., Ostini, L., De Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing. |
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2011 Conference Publication Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediatorsMarbach, J., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing. |
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2011 Conference Publication Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasisSobbe, A., Bridle, K., Jaskowski, L., Ostini, L., de Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing. |
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2011 Conference Publication The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosisHeritage, M. L., Stuart, K. A., Bridle, K. R., Murphy, T. L., Sobbe, A. L., Jaskowski, L. A., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. G. (2011). The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing. |
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2011 Conference Publication Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasisHsu, L., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing. |
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2011 Conference Publication The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular CirrhosisHeritage, M., Stuart, K. A., Bridle, K., Murphy, T. L., Sobbe, A., Jaskowski, L., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing. |
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2011 Conference Publication Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosisBridle, K. R., Sobbe, A., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Fletcher, L. and Crawford, D. H. (2011). Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing. |
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2010 Conference Publication Altered expression of iron-regualtory genes in an animal model of cholestasisSobbe, A. L., Bridle, K.R., Fletcher, L. and Crawford, D, H. G. (2010). Altered expression of iron-regualtory genes in an animal model of cholestasis. Australian Gastroenterology Week 2010, Gold Coast, QLD, Australia, 20-23 October 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2010.06450.x |
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2009 Journal Article Rapamycin Inhibits Hepatic Fibrosis in Rats by Attenuating Multiple Profibrogenic PathwaysBridle, K.R, Popa, C, Morgan, ML, Sobbe, AL, Clouston, AD, Fletcher, LM and Crawford, DHG (2009). Rapamycin Inhibits Hepatic Fibrosis in Rats by Attenuating Multiple Profibrogenic Pathways. Liver Transplantation, 15 (10), 1315-1324. doi: 10.1002/lt.21804 |
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2009 Journal Article Fibrogenesis in Pediatric Cholestatic Liver Disease: Role of Taurocholate and Hepatocyte-Derived Monocyte Chemotaxis Protein-1 in Hepatic Stellate Cell RecruitmentRamm, GA, Shepherd, RW, Hoskins, AC, Greco, SA, Ney, AD, Pereira, TN, Bridle, Kim R., Doecke, JD, Meikle, PJ, Turlin, B and Lewindon, PJ (2009). Fibrogenesis in Pediatric Cholestatic Liver Disease: Role of Taurocholate and Hepatocyte-Derived Monocyte Chemotaxis Protein-1 in Hepatic Stellate Cell Recruitment. Hepatology, 49 (2), 533-544. doi: 10.1002/hep.22637 |
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2009 Conference Publication Expression of fibrogenic genes does not differentiate patients with rapid and non-rapid progression post liver transplant for hepatitis CSobbe, A.L., Bridle, K.R., Morgan, M.L., Lipka, G., Fletcher, L. and Crawford, D.H.G. (2009). Expression of fibrogenic genes does not differentiate patients with rapid and non-rapid progression post liver transplant for hepatitis C. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney Convention & Exhibition Centre, Sydney, NSW, Australia, 21-24 October 2009. Carlton South, Vic.: Blackwell Publishing Asia. |
