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2010 Journal Article Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studiesSarwar, N., Sandhu, M. S., Ricketts, S. L., Butterworth, Adam S., Di Angelantonio, Emanuele, Matthijs Boekholdt, S., Ouwehand, W., Watkins, H., Samani, N. J., Saleheen, D., Lawlor, Debbie, Reilly, Muredach P., Hingorani, A. D., Talmud, P. J., Danesh, J., Braund, P. S., Hall, A. S., Thompson, J., Marz, W., Trip, M., Lawlor, D. A., Casas, J. P., Ebrahim, S., Arsenault, B. J., Boekholdt, S. M., Khaw, K. T., Wareham, N. J., Grallert, H., Illig, T. ... Wood, A. M. (2010). Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studies. The Lancet, 375 (9726), 1634-1639. doi: 10.1016/S0140-6736(10)60545-4 |
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2009 Journal Article Leveraging therapeutic potential of multi-targeted siRNA inhibitorsGe, Qing, Xu, John J., Evans, David M., Mixson, A. James, Yang, Harry Y. and Lu, Patrick Y. (2009). Leveraging therapeutic potential of multi-targeted siRNA inhibitors. Future Medicinal Chemistry, 1 (9), 1671-1681. doi: 10.4155/fmc.09.131 |
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2009 Journal Article Genome-wide association study identifies five loci associated with lung functionRepapi, E., Sayers, I., Wain, L. V., Burton, P. R., Johnson, T., Obeidat, M., Zhao, J. H., Ramasamy, A., Evans, David M., Wellcome Trust Case Control Consortium, Brown, Matthew A. and Bradbury, Linda (2009). Genome-wide association study identifies five loci associated with lung function. Nature Genetics, 42 (1), 36-45. doi: 10.1038/ng.501 |
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2009 Journal Article Genetic Variant m <i>HK1</i> Is Associated With a Proanemic State and A1C but Not Other Glycemic Control-Related TraitsBonnefond, Amelie, Vaxillaire, Martine, Labrune, Yann, Lecoeur, Cecile, Chevre, Jean-Claude, Bouatia-Naji, Nabila, Cauchi, Stephane, Balkau, Beverley, Marre, Michel, Tichet, Jean, Riveline, Jean-Pierre, Hadjadj, Samy, Gallois, Yves, Czernichow, Sebastien, Hercberg, Serge, Kaakinen, Marika, Wiesner, Susanne, Charpentier, Guillaume, Levy-Marchal, Claire, Elliott, Paul, Jarvelin, Marjo-Riitta, Horber, Fritz, Dina, Christian, Pedersen, Oluf, Sladek, Robert, Meyre, David and Froguel, Philippe (2009). Genetic Variant m HK1 Is Associated With a Proanemic State and A1C but Not Other Glycemic Control-Related Traits. Diabetes, 58 (11), 2687-2697. doi: 10.2337/db09-0652 |
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2009 Journal Article Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte VolumeFerreira, MAR, Hottenga, JJ, Warrington, NM, Medland, SE, Willemsen, G, Lawrence, RW, Gordon, S, de Geus, EJC, Henders, AK, Smit, JH, Campbell, MJ, Wallace, L, Evans, DM, Wright, MJ, Nyholt, DR, James, AL, Beilby, JP, Penninx, BW, Palmer, LJ, Frazer, IH, Montgomery, GW, Martin, NG and Boomsma, DI (2009). Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte Volume. AMERICAN JOURNAL OF HUMAN GENETICS, 85 (5), 745-749. doi: 10.1016/j.ajhg.2009.10.005 |
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2009 Journal Article Investigating the genetic association between ERAP1 and ankylosing spondylitisHarvey, David, Pointon, Jennifer J., Evans, David M., Karaderi, Tugce, Farrar, Claire, Appleton, Louise H., Sturrock, Roger D., Stone, Millicent A., Oppermann, Udo, Brown, Matthew A. and Wordsworth, B. Paul (2009). Investigating the genetic association between ERAP1 and ankylosing spondylitis. Human Molecular Genetics, 18 (21), 4204-4212. doi: 10.1093/hmg/ddp371 |
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2009 Journal Article Association and interaction analyses of eight genes under asthma linkage peaksFerreira, M. A. R., Zhao, Z. Z., Thomsen, S. F., James, M., Evans, D. M., Postmus, P. E., Kyvik, K. O., Backer, V., Boomsma, D. I., Martin, N. G., Montgomery, G. W. and Duffy, D. L. (2009). Association and interaction analyses of eight genes under asthma linkage peaks. Allergy, 64 (11), 1623-1628. doi: 10.1111/j.1398-9995.2009.02091.x |
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2009 Journal Article Genetic variant near <i>IRS1</i> is associated with type 2 diabetes, insulin resistance and hyperinsulinemiaRung, Johan, Cauchi, Stephane, Albrechtsen, Anders, Shen, Lishuang, Rocheleau, Ghislain, Cavalcanti-Proenca, Christine, Bacot, Francois, Balkau, Beverley, Belisle, Alexandre, Borch-Johnsen, Knut, Charpentier, Guillaume, Dina, Christian, Durand, Emmanuelle, Elliott, Paul, Hadjadj, Samy, Jaervelin, Marjo-Riitta, Laitinen, Jaana, Lauritzen, Torsten, Marre, Michel, Mazur, Alexander, Meyre, David, Montpetit, Alexandre, Pisinger, Charlotta, Posner, Barry, Poulsen, Pernille, Pouta, Anneli, Prentki, Marc, Ribel-Madsen, Rasmus, Ruokonen, Aimo ... Sladek, Robert (2009). Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nature Genetics, 41 (10), 1110-U89. doi: 10.1038/ng.443 |
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2009 Journal Article Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese populationPimentel-Santos, F. M., Ligeiro, D., Matos, M., Mourao, A. F., Sousa, E., Pinto, P., Ribeiro, A., Sousa, M., Barcelos, A., Godinho, F., Cruz, M., Fonseca, J. E., Guedes-Pinto, H., Trindade, H., Evans, D. M., Brown, M. A. and Branco, J. C. (2009). Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population. Clinical And Experimental Rheumatology, 27 (5), 800-806. |
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2009 Journal Article Genome-wide association study identifies eight loci associated with blood pressure.Newton-Chen, C., Johnson, T., Gateva, V., Tobin, M. D., Bochud, M., Coin, L., Najjar, S. S., Zhao, J. H., et al, Wellcome Trust Case Control Consortium, Brown, Matthew A., Bradbury, Linda and Evans, David (2009). Genome-wide association study identifies eight loci associated with blood pressure.. Nature Genetics, 41 (6), 666-676. doi: 10.1038/ng.361 |
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2009 Journal Article Combined effects of <i>MC4R</i> and <i>FTO</i> common genetic variants on obesity in European general populationsCauchi, Stephane, Stutzmann, Fanny, Cavalcanti-Proenca, Christine, Durand, Emmanuelle, Pouta, Anneli, Hartikainen, Anna-Liisa, Marre, Michel, Vol, Sylviane, Tammelin, Tuija, Laitinen, Jaana, Gonzalez-Izquierdo, Arturo, Blakemore, Alexandra I. F., Elliott, Paul, Meyre, David, Balkau, Beverley, Jaervelin, Marjo-Riitta and Froguel, Philippe (2009). Combined effects of MC4R and FTO common genetic variants on obesity in European general populations. Journal of Molecular Medicine-Jmm, 87 (5), 537-546. doi: 10.1007/s00109-009-0451-6 |
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2009 Journal Article Common variants in the region around Osterix are associated with bone mineral density and growth in childhoodTimpson, Nicholas J., Tobias, Jon H., Richards, J. Brent, Soranzo, Nicole, Duncan, Emma L., Sims, Anne-Maree, Whittaker, Pamela, Kumanduri, Vasudev, Zhai, Guangju, Glaser, Beate, Eisman, John, Jones, Graeme, Nicholson, Geoff, Prince, Richard, Seeman, Ego, Spector, Tim D., Brown, Matthew A., Peltonen, Leena, Smith, George Davey, Deloukas, Panos and Evans, David M. (2009). Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Human Molecular Genetics, 18 (8), 1510-1517. doi: 10.1093/hmg/ddp052 |
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2009 Journal Article Genetic variants in the vitamin D receptor are associated with advanced prostate cancer at diagnosis: Findings from the prostate testing for cancer and treatment study and a systematic reviewChen, Lina, Smith, George Davey, Evans, David M., Cox, Angela, Lawlor, Debbie A., Donovan, Jenny, Yuan, Wei, Day, Ian N. M., Martin, Richard M., Lane, Athene, Rodriguez, Santi, Davis, Michael, Zuccolo, Luisa, Collin, Simon M., Hamdy, Freddie, Neal, David and Lewis, Sarah J. (2009). Genetic variants in the vitamin D receptor are associated with advanced prostate cancer at diagnosis: Findings from the prostate testing for cancer and treatment study and a systematic review. Cancer Epidemiology Biomarkers and Prevention, 18 (11), 2874-2881. doi: 10.1158/1055-9965.EPI-09-0544 |
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2009 Journal Article Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease riskEvans, David M., Visscher, Peter M. and Wray, Naomi R. (2009). Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk. Human Molecular Genetics, 18 (18), 3525-3531. doi: 10.1093/hmg/ddp295 |
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2009 Journal Article A genome-wide association study reveals variants in ARL15 that influence adiponectin levelsBrent Richards, J., Waterworth, Dawn, O'Rahilly, Stephen, Hivert, Marie-France, Loos, Ruth J. F., Perry, John R. B., Tanaka, Toshiko, Timpson, Nicholas John, Semple, Robert K., Soranzo, Nicole, Song, Kijoung, Rocha, Nuno, Grundberg, Elin, Dupuis, Josee, Florez, Jose C., Langenberg, Claudia, Prokopenko, Inga, Saxena, Richa, Sladek, Robert, Aulchenko, Yurii, Evans, David, Waeber, Gerard, Erdmann, Jeanette, Burnett, Mary-Susan, Sattar, Naveed, Devaney, Joseph, Willenborg, Christina, Hingorani, Aroon, Witteman, Jaquelin C. M ... Spector, Tim D. (2009). A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genetics, 5 (12) e1000768, e1000768.1-e1000768.10. doi: 10.1371/journal.pgen.1000768 |
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2009 Journal Article Six new loci associated with body mass index highlight a neuronal influence on body weight regulationWiller, Cristen J., Speliotes, Elizabeth K., Loos, Ruth J. F., Li, Shengxu, Lindgren, Cecilia M., Heid, Iris M., Berndt, Sonja I., Elliot, Amanda L., Jackson, Anne U., Lamina, Claudia, Lettre, Guillaume, Lim, Noha, Lyon, Helen N., McCarroll, Steven N., Papadakis, Konstantinos, Qi, Lu, Randall, Joshua C., Roccasecca, Rosa Maria, Sanna, Serena, Scheet, Paul, Weedon, Michael N., Wheeler, Eleanor, Zhao, Jing Hua, Jacobs, Leonie C., Prokopenko,, Soranzo, Nicole, Tanaka, Toshiko, Timpson, Nicholas J., Almgran, Peter ... GIANT consortium (2009). Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics, 41 (1), 25-34. doi: 10.1038/ng.287 |
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2008 Journal Article Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's diseaseBarrett, Jeffrey C., Wellcome Trust Case Control Consortium, Brown, Matthew A., Bradbury, Linda A., et al. and Evans, David (2008). Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nature Genetics, 40 (8), 955-962. doi: 10.1038/ng.175 |
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2008 Journal Article Common variants near MC4R are associated with fat mass, weight and risk of obesityLoos, Ruth J. F., Evans, David M., Wellcome Trust Case Control Consortium, Brown, Matthew A. and Bradbury, Linda A. (2008). Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genetics, 40 (6), 768-775. doi: 10.1038/ng.140 |
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2008 Journal Article Genome-wide association analysis identifies 20 loci that influence adult heightWeedon, Michael N., Evans, David M., Wellcome Trust Case Control Consortium, Brown, Matthew A. and Bradbury, Linda A. (2008). Genome-wide association analysis identifies 20 loci that influence adult height. Nature Genetics, 40 (5), 575-583. doi: 10.1038/ng.121 |
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2008 Journal Article A genome-wide scan for Eysenckian personality dimensions in adolescent twin sibships: Psychoticism, Extraversion, Neuroticism, and LieGillespie, Nathan A., Zhu, Gu, Evans, David M., Medland, Sarah E., Wright, Margie J. and Martin, Nick G. (2008). A genome-wide scan for Eysenckian personality dimensions in adolescent twin sibships: Psychoticism, Extraversion, Neuroticism, and Lie. Journal of Personality, 76 (6), 1415-1445. doi: 10.1111/j.1467-6494.2008.00527.x |
