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2010

Conference Publication

DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS

Jacobsen, RN, Levesque, JP, Barbier, V, Raggatt, LJ and Pettit, AR (2010). DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS. 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, Melbourne AUSTRALIA, SEP 15-18, 2010. NEW YORK: ELSEVIER SCIENCE INC.

DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS

2009

Conference Publication

Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance

Winkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Smith, Theodore, Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2009). Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 December 2009. Washington, DC, United States: American Society of Hematology.

Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance

2009

Conference Publication

Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood

Levesque, J. P., Barbier, V., Wadley, R. and Winkler, I. G. (2009). Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier.

Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood

2009

Conference Publication

Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance

Winkler, I. G., Levesque, J. P., Barbier, V. and Nowlan, B. (2009). Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier.

Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance

2009

Conference Publication

Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy

Levesque, J. P., Raggatt, L. J., Pettit, A. R., Sims, N. A., Bendall, L. J. and Helwani, F. (2009). Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. NEW YORK: ELSEVIER SCIENCE INC.

Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy

2009

Conference Publication

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

Pettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

2008

Conference Publication

The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis

Shen, Yi, Barbier, Valerie, Winkler, Ingrid G., Hendy, Jean and Levesque, Jean-Pierre (2008). The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology.

The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis

2008

Conference Publication

Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization

Levesque, Jean-Pierre, Sims, Natalie A., Bendall, Linda J., Shen, Yi and Winkler, Ingrid G. (2008). Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology.

Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization

2007

Conference Publication

Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over

Winkler, Ingrid G., Nowlan, Bianca, Barbier, Valerie and Levesque, Jean-Pierre (2007). Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 8-11 December 2007. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V110.11.609.609

Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over

2006

Conference Publication

Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY)

Levesque, Jean-Pierre, Winkler, Ingrid G., Hendy, Jean and Nilsson, Susan K. (2006). Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY). 48th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 9-12 December 2006. Washington, DC United States: American Society of Hematology.

Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY)

2005

Conference Publication

G-CSF potently suppresses osteoblast activity in the bone marrow

Christopher, M. J., Liu, F., Short, B., Simmons, P. J., Winkler, I., Levesque, J. P. and Link, D. C. (2005). G-CSF potently suppresses osteoblast activity in the bone marrow. 47th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 10-13 December 2005. Washington, DC, United States: American Society of Hematology.

G-CSF potently suppresses osteoblast activity in the bone marrow

2004

Conference Publication

Protease-dependent and protease-independent mechanisms of hematopoietic progenitor cell (HPC) mobilization

Levesque, JP, Liu, F, Winkler, IG, Simmons, PJ, Betsuyaku, T, Senior, R, Pham, C and Link, DC (2004). Protease-dependent and protease-independent mechanisms of hematopoietic progenitor cell (HPC) mobilization. 33rd Annual Meeting of the International Society for Experimental Hematology, New Orleans, LA, United States, 17-20 July 2004. Philadelphia, PA, United States: Elsevier.

Protease-dependent and protease-independent mechanisms of hematopoietic progenitor cell (HPC) mobilization

2003

Conference Publication

P-selectin delays the in vitro differentiation of murine lin- Sca-1+c-KIT+ cells whereas E-selectin accelerates their differentiation

Eto, T, Winkler, , Purton, L, Simmons, P and Levesque, JP (2003). P-selectin delays the in vitro differentiation of murine lin- Sca-1+c-KIT+ cells whereas E-selectin accelerates their differentiation. 32nd Annual Scientific Meeting of the International Society for Experimental Hematology, Paris, France, 5-8 July 2003. Philadelphia, PA, United States: Elsevier.

P-selectin delays the in vitro differentiation of murine lin- Sca-1+c-KIT+ cells whereas E-selectin accelerates their differentiation

2002

Conference Publication

Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilization

Levesque, J. P., Hendy, J., Winkler, I. G., Takamatsu, Y. and Simmons, P. J. (2002). Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilization. 44th Annual Meeting of the American-Society-of-Hematology, Philadelphia, PA, United States, 6-10 December 2002. Washington, DC, United States: American Society of Hematology.

Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilization

2001

Conference Publication

Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells

Winkler, IG, Eto, T, Purton, LE, Haylock, DN, Snapp, KR, Kansas, GS, Simmons, PJ and Levesque, JP (2001). Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells. Unknown, Unknown, Unknown. Washington, DC United States: American Society of Hematology.

Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells

2001

Conference Publication

VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapy

Levesque, J. P., Hendy, J., Takamatsu, Y., Williams, B., Winkler, I. G. and Simmons, P. J. (2001). VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapy. *, *, *. Washington, DC, United States: American Society of Hematology.

VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapy

2001

Conference Publication

Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells

Simmons, P. J., Levesque, J. P., Haylock, D. N., Eaves, C. J. and Bühring, H. J. (2001). Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells. Hematopoietic Stem Cells 2000: Basic and Clinical Sciences: Third International Conference, Unknown, June 2001. Malden, MA United States: New York Academy of Sciences. doi: 10.1111/j.1749-6632.2001.tb03590.x

Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells

2000

Conference Publication

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.

Levesque, JP, Takamatsu, Y, Nilsson, SK, Haylock, DN and Simmons, PJ (2000). Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.. WASHINGTON: AMER SOC HEMATOLOGY.

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.

1994

Conference Publication

The mobilization of primitive hemopoietic progenitors into the peripheral blood

Simmons, P. J., Leavesley, D. I., Levesque, J. P., Swart, B. W., Haylock, D. N., To, L. B., Ashman, L. K. and Juttner, C. A. (1994). The mobilization of primitive hemopoietic progenitors into the peripheral blood. Unknown, Unknown, Unknown. Oxford, United Kingdom: Oxford University Press.

The mobilization of primitive hemopoietic progenitors into the peripheral blood

1994

Conference Publication

Purification and release from quiescence of umbilical cord blood early progenitors reveal their potential to engraft adults

Hatzfeld, J., Batard, P., Cardoso, A. A., Li, M. L., Panterne, B., Sansilvestri, P., Ginsbourg, M., Levesque, J. P. and Hatzfeld, A. (1994). Purification and release from quiescence of umbilical cord blood early progenitors reveal their potential to engraft adults. Unknown, Unknown, Unknown. Maryland Heights, MO, United States: Academic Press.

Purification and release from quiescence of umbilical cord blood early progenitors reveal their potential to engraft adults