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2020

Journal Article

Effect of Different Volumes of Interval Training and Continuous Exercise on Interleukin-22 in Adults with Metabolic Syndrome: A Randomized Trial

Ramos, Joyce S., Dalleck, Lance C., Stennett, Rebecca C., Mielke, Gregore I., Keating, Shelley E., Murray, Lydia S., Hasnain, Sumaira Z., Fassett, Robert G., McGuckin, Michael, Croci, Ilaria and Coombes, Jeff S. (2020). Effect of Different Volumes of Interval Training and Continuous Exercise on Interleukin-22 in Adults with Metabolic Syndrome: A Randomized Trial. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 2443-2453. doi: 10.2147/dmso.s251567

Effect of Different Volumes of Interval Training and Continuous Exercise on Interleukin-22 in Adults with Metabolic Syndrome: A Randomized Trial

2020

Journal Article

Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis

Ramsey, Kathryn A., Chen, Alice C. H., Radicioni, Giorgia, Lourie, Rohan, Martin, Megan, Broomfield, Amy, Sheng, Yong H., Hasnain, Sumaira Z., Radford-Smith, Graham, Simms, Lisa A., Burr, Lucy, Thornton, David J., Bowler, Simon D., Livengood, Stephanie, Ceppe, Agathe, Knowles, Michael R., Noone, Peadar G., Donaldson, Scott H., Hill, David B., Ehre, Camille, Button, Brian, Alexis, Neil E., Kesimer, Mehmet, Boucher, Richard C. and McGuckin, Michael A. (2020). Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 201 (6), 661-670. doi: 10.1164/rccm.201906-1219OC

Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis

2019

Journal Article

A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney

Shen, Kunyu, Vesey, David A., Hasnain, Sumaira Z., Zhao, Kong-Nan, Wang, Haolu, Johnson, David W., Saunders, Nicholas, Burgess, Melinda and Gobe, Glenda C. (2019). A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney. Biochemical and Biophysical Research Communications, 522 (3), 736-742. doi: 10.1016/j.bbrc.2019.11.119

A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney

2019

Journal Article

Rationally designed dendritic silica nanoparticles for oral delivery of exenatide

Abeer, Muhammad Mustafa, Meka, Anand Kumar, Pujara, Naisarg, Kumeria, Tushar, Strounina, Ekaterina, Nunes, Rute, Costa, Ana, Sarmento, Bruno, Hasnain, Sumaira Z., Ross, Benjamin P. and Popat, Amirali (2019). Rationally designed dendritic silica nanoparticles for oral delivery of exenatide. Pharmaceutics, 11 (8) 418, 418. doi: 10.3390/pharmaceutics11080418

Rationally designed dendritic silica nanoparticles for oral delivery of exenatide

2019

Journal Article

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

2019

Journal Article

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

Moniruzzaman, Md., Wang, Ran, Jeet, Varinder, McGuckin, Michael A. and Hasnain, Sumaira Z. (2019). Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway. International Journal of Molecular Sciences, 20 (14) 3468, 3468. doi: 10.3390/ijms20143468

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

2019

Journal Article

Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome

Torquati, Luciana, Coombes, Jeff S., Murray, Lydia, Hasnain, Sumaira Z., Mallard, Alistair R., McGuckin, Michael A., Fassett, Robert G., Croci, Ilaria and Ramos, Joyce S. (2019). Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome. Nutrients, 11 (4) 815, 815. doi: 10.3390/nu11040815

Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome

2019

Journal Article

Interleukin-22: friend or foe?

Hasnain, Sumaira Z. and Begun, Jakob (2019). Interleukin-22: friend or foe?. Immunology and Cell Biology, 97 (4), 355-357. doi: 10.1111/imcb.12249

Interleukin-22: friend or foe?

2018

Journal Article

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z. and McGuckin, Michael A. (2018). PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa. PLoS ONE, 13 (8) e0202296, e0202296. doi: 10.1371/journal.pone.0202296

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

2018

Journal Article

Endoplasmic reticulum and oxidative stress in immunopathology: understanding the crosstalk between cellular stress and inflammation

Hasnain, Sumaira Z. (2018). Endoplasmic reticulum and oxidative stress in immunopathology: understanding the crosstalk between cellular stress and inflammation. Clinical and Translational Immunology, 7 (7) e1035, e1035. doi: 10.1002/cti2.1035

Endoplasmic reticulum and oxidative stress in immunopathology: understanding the crosstalk between cellular stress and inflammation

2018

Journal Article

Immune regulation of the unfolded protein response at the mucosal barrier in viral infection

Wang, Ran, Moniruzzaman, Md., Shuffle, Eric, Lourie, Rohan and Hasnain, Sumaira Z. (2018). Immune regulation of the unfolded protein response at the mucosal barrier in viral infection. Clinical & Translational Immunology, 7 (4) e1014, e1014. doi: 10.1002/cti2.1014

Immune regulation of the unfolded protein response at the mucosal barrier in viral infection

2017

Journal Article

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip and Forbes, Josephine M. (2017). Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets, 10 (1), 10-24. doi: 10.1080/19382014.2017.1405189

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

2017

Journal Article

Goblet cells as mucosal sentinels for immunity

McGuckin, M. A. and Hasnain, S. Z. (2017). Goblet cells as mucosal sentinels for immunity. Mucosal Immunology, 10 (5), 1118-1121. doi: 10.1038/mi.2016.132

Goblet cells as mucosal sentinels for immunity

2017

Journal Article

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

Borg, Danielle J., Wang, Ran, Murray, Lydia, Tong, Hui, Steptoe, Raymond J., McGuckin, Michael A. and Hasnain, Sumaira Z. (2017). The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse. Diabetologia, 60 (11), 1-6. doi: 10.1007/s00125-017-4392-2

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

2017

Journal Article

Analyzing the properties of murine intestinal mucins by electrophoresis and histology

Wang, Ran and Hasnain, Sumaira Z. (2017). Analyzing the properties of murine intestinal mucins by electrophoresis and histology. Bio-protocol, 7 (14). doi: 10.21769/BioProtoc.2394

Analyzing the properties of murine intestinal mucins by electrophoresis and histology

2017

Journal Article

Human diseases, immunity and the oral microbiota-Insights gained from metagenomic studies

Idris, Adi, Hasnain, Sumaira Z., Huat, Lu Z. and Koh, David (2017). Human diseases, immunity and the oral microbiota-Insights gained from metagenomic studies. Oral Science International, 14 (2), 27-32. doi: 10.1016/S1348-8643(16)30024-6

Human diseases, immunity and the oral microbiota-Insights gained from metagenomic studies

2017

Journal Article

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

Hasnain, Sumaira Z., Dawson, Paul A., Lourie, Rohan, Hutson, Peter, Tong, Hui, Grencis, Richard K., McGuckin, Michael A. and Thornton, David J. (2017). Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion. PLoS Pathogens, 13 (2) e1006218, e1006218. doi: 10.1371/journal.ppat.1006218

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

2017

Journal Article

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

Varelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P. A ., Hugenholtz, Philip and Hill, Geoffrey R. (2017). Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Blood, 129 (15), 2172-2185. doi: 10.1182/blood-2016-08-732628

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

2016

Journal Article

MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target

Sheng, Y. H., He, Y., Hasnain, S. Z., Wang, R., Tong, H., Clarke, D. T., Lourie, R., Oancea, I., Wong, K. Y., Lumley, J. W., Florin, T. H., Sutton, P., Hooper, J. D., McMillan, N. A. and McGuckin, M. A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target. Oncogene, 36 (5), 700-713. doi: 10.1038/onc.2016.241

MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target

2016

Journal Article

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuiv, Paraic O., McGuckin, Michael A. and Hasnain, Sumaira Z. (2016). High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. Scientific Reports, 6 (1) 28990, 28990. doi: 10.1038/srep28990

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22