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2015 Journal Article Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiaeWilliams, Thomas C., Espinosa, Monica I., Nielsen, Lars K. and Vickers, Claudia E. (2015). Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiae. Microbial Cell Factories, 14 (43) 43, 1-10. doi: 10.1186/s12934-015-0223-7 |
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2015 Journal Article Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencingClark, Michael B., Mercer, Tim R., Bussotti, Giovanni, Leonardi, Tommaso, Haynes, Katelin R., Crawford, Joanna, Brunck, Marion E., Cao, Kim-Anh Le, Thomas, Gethin P., Chen, Wendy Y., Taft, Ryan J., Nielsen, Lars K., Enright, Anton J., Mattick, John S. and Dinger, Marcel E. (2015). Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. Nature Methods, 12 (4), 339-342. doi: 10.1038/nmeth.3321 |
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2015 Journal Article High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesisOrellana, Camila A., Marcellin, Esteban, Schulz, Benjamin L., Nouwens, Amanda S., Gray, Peter P. and Nielsen, Lars K. (2015). High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis. Journal of Proteome Research, 14 (2), 609-618. doi: 10.1021/pr501027c |
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2015 Journal Article Genome-wide discovery of human splicing branchpointsMercer, Tim R., Clark, Michael B., Anderson, Stacey B., Brunck, Marion E., Haerty, Wilifried, Crawford, Joanna, Taft, Ryan J., Nielsen, Lars K., Dinger, Marcel E. and Mattick, John S. (2015). Genome-wide discovery of human splicing branchpoints. Genome Research, 25 (2), 290-303. doi: 10.1101/gr.182899.114 |
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2015 Journal Article A multi-tissue genome-scale metabolic modelling framework for the analysis of whole plant systemsde Oliveira Dal'molin, Cristiana Gomes, Quek, Lake-Ee, Saa, Pedro A. and Nielsen, Lars K. (2015). A multi-tissue genome-scale metabolic modelling framework for the analysis of whole plant systems. Frontiers in Plant Science, 6 (JAN) 4, 4.1-4.12. doi: 10.3389/fpls.2015.00004 |
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2015 Journal Article AllR controls the expression of Streptomyces coelicolor allantoin pathway genesNavone, Laura, Pablo Macagno, Juan, Licona-Cassani, Cuauhtemoc, Marcellin, Esteban, Nielsen, Lars K., Gramajo, Hugo and Rodriguez, Eduardo (2015). AllR controls the expression of Streptomyces coelicolor allantoin pathway genes. Applied and Environmental Microbiology, 81 (19), 6649-6659. doi: 10.1128/AEM.02098-15 |
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2015 Journal Article Editorial: On the cusp of rational CHO cell engineeringNielsen, Lars and Borth, Nicole (2015). Editorial: On the cusp of rational CHO cell engineering. Biotechnology Journal, 10 (7), 929-930. doi: 10.1002/biot.201500375 |
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2015 Journal Article Systems biology and metabolic modelling unveils limitations to polyhydroxybutyrate accumulation in sugarcane leaves; lessons for C4 engineeringMcQualter, Richard B., Bellasio, Chandra, Gebbie, Leigh K., Petrasovits, Lars A., Palfreyman, Robin W., Hodson, Mark P., Plan, Manuel R., Blackman, Deborah M., Brumbley, Stevens M. and Nielsen, Lars K. (2015). Systems biology and metabolic modelling unveils limitations to polyhydroxybutyrate accumulation in sugarcane leaves; lessons for C4 engineering. Plant Biotechnology Journal, 14 (2), 1-14. doi: 10.1111/pbi.12399 |
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2015 Journal Article Decline in Helicoverpa armigera nucleopolyhedrovirus occlusion body yields with increasing infection cell density in vitro is strongly correlated with viral DNA levelsHuynh, Hoai T., Tran, Trinh T. B., Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2015). Decline in Helicoverpa armigera nucleopolyhedrovirus occlusion body yields with increasing infection cell density in vitro is strongly correlated with viral DNA levels. Archives of Virology, 160 (9), 2169-2180. doi: 10.1007/s00705-015-2478-z |
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2014 Journal Article The use of an acetoacetyl-CoA synthase in place of a β-ketothiolase enhances poly-3-hydroxybutyrate production in sugarcane mesophyll cellsMcQualter, Richard B., Petrasovits, Lars A., Gebbie, Leigh K., Schweitzer, Dirk, Blackman, Deborah M., Chrysanthopoulos, Panagiotis, Hodson, Mark P., Plan, Manuel R., Riches, James D., Snell, Kristi D., Brumbley, Stevens M. and Nielsen, Lars K. (2014). The use of an acetoacetyl-CoA synthase in place of a β-ketothiolase enhances poly-3-hydroxybutyrate production in sugarcane mesophyll cells. Plant Biotechnology Journal, 13 (5), 700-707. doi: 10.1111/pbi.12298 |
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2014 Journal Article Effect of the peak cell density of recombinant AcMNPV-infected Hi5 cells on baculovirus yieldsHuynh, Hoai T., Tran, Trinh T. B., Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2014). Effect of the peak cell density of recombinant AcMNPV-infected Hi5 cells on baculovirus yields. Applied Microbiology and Biotechnology, 99 (4), 1687-1700. doi: 10.1007/s00253-014-6260-z |
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2014 Journal Article Dynamic balancing of isoprene carbon sources reflects photosynthetic and photorespiratory responses to temperature stressJardine, Kolby, Chambers, Jeffrey, Alves, Eliane G., Teixeira, Andrea, Garcia, Sabrina, Holm, Jennifer, Higuchi, Niro, Manzi, Antonio, Abrell, Leif, Fuentes, Jose D., Nielsen, Lars K., Torn, Margaret S. and Vickers, Claudia E. (2014). Dynamic balancing of isoprene carbon sources reflects photosynthetic and photorespiratory responses to temperature stress. Plant Physiology, 166 (4), 2051-2064. doi: 10.1104/pp.114.247494 |
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2014 Journal Article Absolute counting of neutrophils in whole blood using flow cytometryBrunck, Marion E. G., Andersen, Stacey B., Timmins, Nicholas E., Osborne, Geoffrey W. and Nielsen, Lars K. (2014). Absolute counting of neutrophils in whole blood using flow cytometry. Cytometry Part A, 85 (12), 1057-1064. doi: 10.1002/cyto.a.22503 |
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2014 Journal Article Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrationsTurner, Jennifer, Quek,Lake-Ee, Titmarsh, Drew, Kromer, Jens O., Kao, Li-Pin, Nielsen, Lars, Wolvetang, Ernst and Cooper-White, Justin (2014). Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations. PLoS One, 9 (11) e112757, e112757.1-e112757.13. doi: 10.1371/journal.pone.0112757 |
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2014 Journal Article Escherichia coli W shows fast, highly oxidative sucrose metabolism and low acetate formationArifin, Yalun, Archer, Colin, Lim, SooA, Quek, Lake-Ee, Sugiarto, Haryadi, Marcellin, Esteban, Vickers, Claudia E., Kromer, Jens O. and Nielsen, Lars K. (2014). Escherichia coli W shows fast, highly oxidative sucrose metabolism and low acetate formation. Applied Microbiology and Biotechnology, 98 (21), 9033-9044. doi: 10.1007/s00253-014-5956-4 |
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2014 Journal Article Specific mesothelial signature marks the heterogeneity of mesenchymal stem cells from high-grade serous ovarian cancerVerardo, Roberto, Piazza, Silvano, Klaric, Enio, Ciani, Yari, Bussadori, Giulio, Marzinotto, Stefania, Mariuzzi, Laura, Cesselli, Daniela, Beltrami, Antonio P., Mano, Miguel, Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Carninci, Piero, Hayashizaki, Yoshihide, Forrest, Alistair R. R., Beltrami, Carlo A., The Fantom Consortium, Schneider, Claudio, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Wolvetang, Ernst, Hitchens, Kelly, Kenna, Tony, Blumenthal, Antje, Briggs, James, Ovchinnikov, Dmitry, Fearnley, Liam ... Nielsen, Lars (2014). Specific mesothelial signature marks the heterogeneity of mesenchymal stem cells from high-grade serous ovarian cancer. Stem Cells (Durham), 32 (11), 2998-3011. doi: 10.1002/stem.1791 |
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2014 Journal Article Factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrassMcQualter, Richard B., Somleva, Maria N., Gebbie, Leigh K., Li, Xuemei, Petrasovits, Lars A., Snell, Kristi D., Nielsen, Lars K. and Brumbley, Stevens M. (2014). Factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrass. BMC Biotechnology, 14 (1) 83, 83.1-83.11. doi: 10.1186/1472-6750-14-83 |
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2014 Journal Article Control of chitin and N-acetylglucosamine utilization in Saccharopolyspora erythraeaLiao, Chengheng, Rigali, Sebastien, Cassani, Cuauhtemoc Licona, Marcellin, Esteban, Nielsen, Lars Keld and Ye, Bang-Ce (2014). Control of chitin and N-acetylglucosamine utilization in Saccharopolyspora erythraea. Microbiology (United Kingdom), 160 (9), 1914-1928. doi: 10.1099/mic.0.078261-0 |
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2014 Journal Article Reducing Recon 2 for steady-state flux analysis of HEK cell cultureQuek, Lake-Ee, Dietmair, Stefanie, Hanscho, Michael, Martinez, Veronica S., Borth, Nicole and Nielsen, Lars K. (2014). Reducing Recon 2 for steady-state flux analysis of HEK cell culture. Journal of Biotechnology, 184, 172-178. doi: 10.1016/j.jbiotec.2014.05.021 |
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2014 Journal Article Production of the short peptide surfactant DAMP4 from glucose or sucrose in high cell density cultures of Escherichia coli BL21(DE3)Bruschi, Michele, Kroemer, Jens O., Steen, Jennifer A. and Nielsen, Lars K. (2014). Production of the short peptide surfactant DAMP4 from glucose or sucrose in high cell density cultures of Escherichia coli BL21(DE3). Microbial Cell Factories, 13 (1) 99, 1-9. doi: 10.1186/s12934-014-0099-y |
