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2005

Journal Article

Molecular characterization and cancer risk associated with BRCA1 and BRCA2 splice site variants identified in multiple-case breast cancer families

Tesoriero, A. A., Wong, E. M., Jenkins, M. A., Hopper, J. L., KConFab, K. C. F., Brown, M. A., Chenevix-Trench, G., Spurdle, A. B. and Southey, M. C. (2005). Molecular characterization and cancer risk associated with BRCA1 and BRCA2 splice site variants identified in multiple-case breast cancer families. Human Mutation, 26 (5), 495-495. doi: 10.1002/humu.9379

Molecular characterization and cancer risk associated with BRCA1 and BRCA2 splice site variants identified in multiple-case breast cancer families

2005

Journal Article

Method for the generation and cultivation of functional three-dimensional mammary constructs without exogenous extracellular matrix

Timmins, N. E., Harding, F. J., Smart, C. E., Brown, M. A. and Nielsen, L. K. (2005). Method for the generation and cultivation of functional three-dimensional mammary constructs without exogenous extracellular matrix. Cell And Tissue Research, 320 (1), 207-210. doi: 10.1007/s00441-004-1064-6

Method for the generation and cultivation of functional three-dimensional mammary constructs without exogenous extracellular matrix

2004

Journal Article

MMTV-trBrca 1 mice display strain-dependent abnormalities in vaginal development

Simpson, K. J., Wati, M. R., Deans, A. J., Lindeman, G. J. and Brown, M. A. (2004). MMTV-trBrca 1 mice display strain-dependent abnormalities in vaginal development. International Journal of Developmental Biology, 48 (7), 675-678. doi: 10.1387/ijdb.041849ks

MMTV-trBrca 1 mice display strain-dependent abnormalities in vaginal development

2004

Journal Article

Brca1 inactivation induces p27Kip1-dependent cell cycle arrest and delayed development in the mouse mammary gland

Deans, Andrew J., Simpson, Kaylene J., Trivett, Melanie K., Brown, Melissa A. and McArthur, Grant (2004). Brca1 inactivation induces p27Kip1-dependent cell cycle arrest and delayed development in the mouse mammary gland. Oncogene, 23 (36), 6136-6145. doi: 10.1038/sj.onc.1207805

Brca1 inactivation induces p27Kip1-dependent cell cycle arrest and delayed development in the mouse mammary gland

2004

Journal Article

Roles of heterogeneous nuclear ribonucleoproteins A/B in cell growth

He, Y., Brown, M. A., Rothnagel, J. A., Saunders, N. A. and Smith, R. (2004). Roles of heterogeneous nuclear ribonucleoproteins A/B in cell growth. Molecular Biology of The Cell, 15, 252A-253A.

Roles of heterogeneous nuclear ribonucleoproteins A/B in cell growth

2002

Journal Article

Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice

Brown, M. A., Nicolai, H., Howe, K., Katagiri, T., Lalani, E., Simpson, K. J., Manning, N. W., Deans, A., Chen, P., Khanna, K. K., Wati, M. R., Griffiths, B. L., Xu, C. F., Stamp, G. W. H. and Solomon, E. (2002). Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice. Transgenic Research, 11 (5), 467-478. doi: 10.1023/A:1020348025139

Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice

2002

Journal Article

Germline BRCA1 promoter deletions in UK and Australian familial breast cancer patients: Identification of a novel deletion consistent with BRCA1 :psi VBRCA1 recombination

Brown, M. A., Lo, L. J., Catteau, A., Xu, C. F., Lindeman, G. J., Hodgson, S. and Solomon, E. (2002). Germline BRCA1 promoter deletions in UK and Australian familial breast cancer patients: Identification of a novel deletion consistent with BRCA1 :psi VBRCA1 recombination. Human Mutation, 19 (4), 435-442. doi: 10.1002/humu.10055

Germline BRCA1 promoter deletions in UK and Australian familial breast cancer patients: Identification of a novel deletion consistent with BRCA1 :psi VBRCA1 recombination

2000

Journal Article

Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice

Lane, T. F., Lin, C. W., Brown, M. A., Solomon, E. and Leder, P. (2000). Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice. Oncogene, 19 (36), 4085-4090. doi: 10.1038/sj.onc.1203760

Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice

1999

Journal Article

Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions

Catteau, A., Xu, C. F., Brown, M. A., Hodgson, S., Greenman, J., Mathew, C. G., Dunning, A. M. and Solomon, E. (1999). Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions. British Journal of Cancer, 79 (5-6), 759-763. doi: 10.1038/sj.bjc.6690122

Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions

1997

Journal Article

Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene

Xu, CF, Brown, MA, Nicolai, H, Chambers, JA, Griffiths, BL and Solomon, E (1997). Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene. Human Molecular Genetics, 6 (7), 1057-1062. doi: 10.1093/hmg/6.7.1057

Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene

1997

Journal Article

Studies on inherited cancers: Outcomes and challenges of 25 years

Brown, MA and Solomon, E (1997). Studies on inherited cancers: Outcomes and challenges of 25 years. Trends in Genetics, 13 (5), 202-206. doi: 10.1016/S0168-9525(97)01132-3

Studies on inherited cancers: Outcomes and challenges of 25 years

1997

Journal Article

Mutations and alternative splicing of the BRCAI gene in UK breast/ovarian cancer families

Xu, CF, Chambers, JA, Nicolai, H, Brown, MA, Hujeirat, Y, Mohammed, S, Hodgson, S, Kelsell, DP, Spurr, NK, Bishop, DT and Solomon, E (1997). Mutations and alternative splicing of the BRCAI gene in UK breast/ovarian cancer families. Genes Chromosomes & Cancer, 18 (2), 102-110. doi: 10.1002/(SICI)1098-2264(199702)18:23.0.CO;2-6

Mutations and alternative splicing of the BRCAI gene in UK breast/ovarian cancer families

1997

Journal Article

Tumor suppressor genes and human cancer

Brown, MA (1997). Tumor suppressor genes and human cancer. Advances in Genetics, Vol 36, 36 (C), 45-135. doi: 10.1016/S0065-2660(08)60307-7

Tumor suppressor genes and human cancer

1996

Journal Article

The 5' end of the BRCA1 gene lies within a duplicated region of human chromosome 17q21

Brown, MA, Xu, CF, Nicolai, H, Griffiths, B, Chambers, JA, Black, D and Solomon, E (1996). The 5' end of the BRCA1 gene lies within a duplicated region of human chromosome 17q21. Oncogene, 12 (12), 2507-2513.

The 5' end of the BRCA1 gene lies within a duplicated region of human chromosome 17q21

1995

Journal Article

Distinct Transcription Start Sites Generate 2 Forms of Brca1 Messenger-Rna

Xu, CF, Brown, MA, Chambers, JA, Griffiths, B, Nicolai, H and Solomon, E (1995). Distinct Transcription Start Sites Generate 2 Forms of Brca1 Messenger-Rna. Human Molecular Genetics, 4 (12), 2259-2264. doi: 10.1093/hmg/4.12.2259

Distinct Transcription Start Sites Generate 2 Forms of Brca1 Messenger-Rna

1995

Journal Article

Physical Mapping, Cloning, and Identification of Genes Within a 500-Kb Region Containing Brca1

Brown, MA, Jones, KA, Nicolai, H, Bonjardim, M, Black, D, McFarlane, R, Dejong, P, Quirk, JP, Lehrach, H and Solomon, E (1995). Physical Mapping, Cloning, and Identification of Genes Within a 500-Kb Region Containing Brca1. Proceedings of the National Academy of Sciences of the United States of America, 92 (10), 4362-4366. doi: 10.1073/pnas.92.10.4362

Physical Mapping, Cloning, and Identification of Genes Within a 500-Kb Region Containing Brca1

1995

Journal Article

Molecular genetics of sporadic and familial breast cancer

Jones, KA, Brown, MA and Solomon, E (1995). Molecular genetics of sporadic and familial breast cancer. Cancer Surveys, 25, 315-334.

Molecular genetics of sporadic and familial breast cancer

1994

Journal Article

Regulation of Brca1

Brown, MA, Nicolai, H, Xu, CF, Griffiths, BL, Jones, KA, Solomon, E, Hosking, L, Trowsdale, J, Black, DM and McFarlane, R (1994). Regulation of Brca1. Nature, 372 (6508), 733-733. doi: 10.1038/372733a0

Regulation of Brca1

1994

Journal Article

The Detailed Characterization of a 400-Kb Cosmid Walk in the Brca1 Region - Identification and Localization of 10 Genes Including a Dual-Specificity Phosphatase

Jones, KA, Black, DM, Brown, MA, Griffiths, BL, Nicolai, HM, Chambers, JA, Bonjardim, M, Xu, CF, Boyd, M, McFarlane, R, Korn, B, Poustka, A, North, MA, Schalkwyk, L, Lehrach, H and Solomon, E (1994). The Detailed Characterization of a 400-Kb Cosmid Walk in the Brca1 Region - Identification and Localization of 10 Genes Including a Dual-Specificity Phosphatase. Human Molecular Genetics, 3 (11), 1927-1934.

The Detailed Characterization of a 400-Kb Cosmid Walk in the Brca1 Region - Identification and Localization of 10 Genes Including a Dual-Specificity Phosphatase

1994

Journal Article

No Evidence for Gm-Csf Receptor a Chain Gene Mutation in Aml-M2 Leukemias Which Have Lost a Sex-Chromosome

Brown, MA, Harrisonsmith, M, Deluca, E, Begley, CG and Gough, NM (1994). No Evidence for Gm-Csf Receptor a Chain Gene Mutation in Aml-M2 Leukemias Which Have Lost a Sex-Chromosome. Leukemia, 8 (10), 1774-1779.

No Evidence for Gm-Csf Receptor a Chain Gene Mutation in Aml-M2 Leukemias Which Have Lost a Sex-Chromosome