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2023 Journal Article Kinetico-mechanistic studies on a reactive organocopper(II) complex: Cu–C bond homolysis versus heterolysisGonzálvez, Miguel A., Williams, Craig M., Martínez, Manuel and Bernhardt, Paul V. (2023). Kinetico-mechanistic studies on a reactive organocopper(II) complex: Cu–C bond homolysis versus heterolysis. Inorganic Chemistry, 62 (11), 4662-4671. doi: 10.1021/acs.inorgchem.3c00127 |
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2023 Journal Article Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effectsSmith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2023). Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effects. Journal of Medicinal Chemistry, 66 (6), 3746-3784. doi: 10.1021/acs.jmedchem.2c01695 |
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2023 Journal Article seco-pregnane glycosides from Australian caustic vine (Cynanchum viminale subsp. australe)Xue, Yongbo, Savchenko, Andrei I., Agnew-Francis, Kylie A., Miles, Jared A., Holt, Tina, Lu, Hieng, Chow, Sharon, Forster, Paul I., Boyle, Glen M., Ross, Benjamin P., Fischer, Katja, Kutateladze, Andrei G. and Williams, Craig M. (2023). seco-pregnane glycosides from Australian caustic vine (Cynanchum viminale subsp. australe). Journal of Natural Products, 86 (3), 490-497. doi: 10.1021/acs.jnatprod.2c01037 |
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2023 Journal Article A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductaseJin, Da-Yun, Chen, Xuejie, Liu, Yizhou, Williams, Craig M., Pedersen, Lars C., Stafford, Darrel W. and Tie, Jian-Ke (2023). A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase. Nature Communications, 14 (1) 828, 1-14. doi: 10.1038/s41467-023-36446-8 |
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2023 Journal Article Structural Reassignment of Two Polyenol Natural ProductsKutateladze, Andrei G., Bates, Roderick W., Elyashberg, Mikhail and Williams, Craig M. (2023). Structural Reassignment of Two Polyenol Natural Products. European Journal of Organic Chemistry, 26 (9) e202201316. doi: 10.1002/ejoc.202201316 |
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2023 Journal Article Chiral auxiliary-directed site-selective deprotonation of the cubane skeletonTakebe, Hiyori, Yoshino, Nana, Shimada, Yukako, Williams, Craig M. and Matsubara, Seijiro (2023). Chiral auxiliary-directed site-selective deprotonation of the cubane skeleton. Organic Letters, 25 (1), 27-30. doi: 10.1021/acs.orglett.2c03659 |
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2022 Journal Article Unearthing the subtleties of rhodium(II)-catalyzed carbenoid cycloadditions to furans with an N-sulfonyl-1,2,3-triazole probeBettencourt, Christian J., Krainz, Tanja, Chow, Sharon, Parr, Brendan T., Tracy, William F., Bernhardt, Paul V., Davies, Huw M. L. and Williams, Craig M. (2022). Unearthing the subtleties of rhodium(II)-catalyzed carbenoid cycloadditions to furans with an N-sulfonyl-1,2,3-triazole probe. Organic Letters, 24 (50), 9290-9295. doi: 10.1021/acs.orglett.2c03869 |
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2022 Journal Article Structural basis of resistance to herbicides that target acetohydroxyacid synthaseLonhienne, Thierry, Cheng, Yan, Garcia, Mario D., Hu, Shu Hong, Low, Yu Shang, Schenk, Gerhard, Williams, Craig M. and Guddat, Luke W. (2022). Structural basis of resistance to herbicides that target acetohydroxyacid synthase. Nature Communications, 13 (1) 3368, 3368. doi: 10.1038/s41467-022-31023-x |
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2022 Journal Article Wasabi (Eutrema japonicum) reduces obesity and blood pressure in diet-induced metabolic syndrome in ratsThomaz, Fernanda Santos, Tan, Yuen P., Williams, Craig M., Ward, Leigh C., Worrall, Simon and Panchal, Sunil K. (2022). Wasabi (Eutrema japonicum) reduces obesity and blood pressure in diet-induced metabolic syndrome in rats. Foods, 11 (21) 3435, 1-12. doi: 10.3390/foods11213435 |
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2022 Journal Article Reassignment of improbable natural products identified through chemical principle screeningElyashberg, Mikhail, Novitskiy, Ivan M., Bates, Roderick W., Kutateladze, Andrei G. and Williams, Craig M. (2022). Reassignment of improbable natural products identified through chemical principle screening. European Journal of Organic Chemistry, 2022 (34) e202200572, 1-9. doi: 10.1002/ejoc.202200572 |
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2022 Journal Article Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic painKong, Dehui, Saqer, Alaa A., Carpinelli de Jesus, Matheus, Khan, Nemat, Jones, Alun, Blanchfield, Joanne T., Smith, Maree T. and Williams, Craig M. (2022). Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain. Bioorganic and Medicinal Chemistry, 69 116889, 1-10. doi: 10.1016/j.bmc.2022.116889 |
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2022 Journal Article Photochemical generation of the 2-azabicyclo[4.2.0]octa-4,7-diene skeletonFahrenhorst-Jones, Tyler, Savage, G. Paul and Williams, Craig M. (2022). Photochemical generation of the 2-azabicyclo[4.2.0]octa-4,7-diene skeleton. Australian Journal of Chemistry, 75 (11), 884-887. doi: 10.1071/ch22139 |
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2022 Journal Article Genome-guided analysis of seven weed species reveals conserved sequence and structural features of key gene targets for herbicide developmentShah, Sarah, Lonhienne, Thierry, Murray, Cody-Ellen, Chen, Yibi, Dougan, Katherine E., Low, Yu Shang, Williams, Craig M., Schenk, Gerhard, Walter, Gimme H., Guddat, Luke W. and Chan, Cheong Xin (2022). Genome-guided analysis of seven weed species reveals conserved sequence and structural features of key gene targets for herbicide development. Frontiers in Plant Science, 13 909073. doi: 10.3389/fpls.2022.909073 |
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2022 Journal Article Toward the total synthesis of alpkinidine: synthesis of haloquinone CE ring system synthons and attempted nucleophilic bisannulationBuccini, Marco, Tham, Louisa, Dhoro, Francis, Skelton, Brian W., Williams, Craig M. and Piggott, Matthew J. (2022). Toward the total synthesis of alpkinidine: synthesis of haloquinone CE ring system synthons and attempted nucleophilic bisannulation. ACS Omega, 7 (23), 19080-19092. doi: 10.1021/acsomega.2c02116 |
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2022 Journal Article Toward the total synthesis of alpkinidine: Michael addition to isoquinolinetrione CE ring-system synthonsBuccini, Marco, Dhoro, Francis, Tham, Louisa, Skelton, Brian W., Williams, Craig M. and Piggott, Matthew J. (2022). Toward the total synthesis of alpkinidine: Michael addition to isoquinolinetrione CE ring-system synthons. ACS Omega, 7 (23), 19093-19105. doi: 10.1021/acsomega.2c02117 |
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2022 Journal Article Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K‐dependent carboxylationChen, Xuejie, Furukawa, Natsuko, Jin, Da‐Yun, Liu, Yizhou, Stafford, Darrel W., Williams, Craig M., Suhara, Yoshitomo and Tie, Jian‐Ke (2022). Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K‐dependent carboxylation. The FEBS Journal, 289 (9), 2613-2627. doi: 10.1111/febs.16291 |
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2022 Journal Article The (±)-6-Aza[1.0]triblattane skeleton: contraction beyond the Wilder–Culberson ring systemFahrenhorst-Jones, Tyler, Bernhardt, Paul V., Savage, G. Paul and Williams, Craig M. (2022). The (±)-6-Aza[1.0]triblattane skeleton: contraction beyond the Wilder–Culberson ring system. Organic Letters, 24 (3) acs.orglett.1c04240, 903-906. doi: 10.1021/acs.orglett.1c04240 |
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2022 Journal Article Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sourcesSmith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2022). Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources. Journal of Medicinal Chemistry, 65 (3) acs.jmedchem.0c01915, 1612-1661. doi: 10.1021/acs.jmedchem.0c01915 |
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2022 Journal Article Organocopper(II) complexes: new catalysts for carbon–carbon bond formation via electrochemical atom transfer radical addition (eATRA)Gonzálvez, Miguel A., Su, Chuyi, Williams, Craig M. and Bernhardt, Paul V. (2022). Organocopper(II) complexes: new catalysts for carbon–carbon bond formation via electrochemical atom transfer radical addition (eATRA). Chemical Science, 13 (35), 10506-10511. doi: 10.1039/d2sc03418b |
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2021 Journal Article Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianesCullen, Jason K., Boyle, Glen M., Yap, Pei-Yi, Elmlinger, Stefan, Simmons, Jacinta L., Broit, Natasa, Johns, Jenny, Ferguson, Blake, Maslovskaya, Lidia A., Savchenko, Andrei I., Mirzayans, Paul Malek, Porzelle, Achim, Bernhardt, Paul V., Gordon, Victoria A., Reddell, Paul W., Pagani, Alberto, Appendino, Giovanni, Parsons, Peter G. and Williams, Craig M. (2021). Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes. Scientific Reports, 11 (1) 207, 207. doi: 10.1038/s41598-020-80397-9 |
