Overview
Background
- My academic qualifications include a PhD in Neurosciences, an MSc in Biochemistry and Molecular Biology, and a Bachelor of Medicine.
- I have initiated and managed multiple projects to develop novel therapeutics for neurological disorders, including: 1) Developing a nanoparticle-based siRNA delivery system for the treatment of Huntington’s disease (ARC project; as Postdoctoral Research Fellow). 2) Examining the treatment effects of intravenous immunoglobulin (IVIg) on epilepsy (Advance Queensland Women’s Academic Fund; as Sole Investigator). 2) Examining the effectiveness of three neuroinflammation modulatory agents on traumatic brain injury and epilepsy through randomised controlled preclinical trials (Seed projects sponsored by industry partners: VivaZome Therapeutics, Implicit Bioscience, and Innate Immunotherapeutics; as Co-investigator). 3) Developing treatment strategies to prevent the development of epilepsy after severe traumatic brain injury and identifying medical imaging biomarkers to evaluate the risk of epilepsy post-injury (two U.S. Department of Defense, Congressionally Directed Medical Research Programs; as Co-investigator). 4) Developing exosomal therapy for traumatic brain injury (Cooperative Research Centres Projects (CRC-P) Grant with two research groups from academic institutions and three pharmaceutical companies; as Principal Investigator).
Availability
- Dr Min Chen is:
- Available for supervision
Fields of research
Qualifications
- Postgraduate Diploma, University of the Chinese Academy of Science
- Doctor of Philosophy, University of the Chinese Academy of Science
Research interests
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Preventing the development of post-traumatic epilepsy
Developing treatment strategies to prevent the development of epilepsy after severe traumatic brain injury and identifying medical imaging biomarkers to evaluate the risk of epilepsy post-injury
Research impacts
My major achievements from my career in research include: • Securing over AUD 2.5 million in research grants from government and industry funding bodies as a Chief Investigator. • Publishing 26 high-impact papers (Citations: 1,479, H-index: 18, i10-index: 22). • Winning first prize in the International Seizure Prediction contest, sponsored by the National Institutes of Health (NIH) and the American Epilepsy Society.
Works
Search Professor Min Chen’s works on UQ eSpace
2007
Journal Article
Alterations of pulmonary zinc homeostasis and cytokine production following traumatic brain injury in rats
Zhu, Lin, Yan, Wei, Qi, Meng, Hu, Ze Lan, Lu, Ting Jia, Chen, Min, Zhou, Jin, Hang, Chun Hua and Shi, Ji Xin (2007). Alterations of pulmonary zinc homeostasis and cytokine production following traumatic brain injury in rats. Annals of Clinical and Laboratory Science, 37 (4), 356-361.
2003
Journal Article
Possible mechanisms underlying the protective effects of SY-21, an extract of a traditional Chinese herb, on transient brain ischemia/reperfusion- induced neuronal death in rat hippocampus
Chen, Min, Wang, Yao, Liu, Yong, Hou, Xiao-Yu, Zhang, Quan-Guang, Meng, Fan-Jie and Zhang, Guang-Yi (2003). Possible mechanisms underlying the protective effects of SY-21, an extract of a traditional Chinese herb, on transient brain ischemia/reperfusion- induced neuronal death in rat hippocampus. Brain Research, 989 (2), 180-186. doi: 10.1016/S0006-8993(03)03331-6
2003
Journal Article
Tyrosine kinase and tyrosine phosphatase participate in regulation of interactions of NMDA receptor subunit 2A with Src and Fyn mediated by PSD-95 after transient brain ischemia
Chen, Min, Hou, XiaoYu and Zhang, GuangYi (2003). Tyrosine kinase and tyrosine phosphatase participate in regulation of interactions of NMDA receptor subunit 2A with Src and Fyn mediated by PSD-95 after transient brain ischemia. Neuroscience Letters, 339 (1), 29-32. doi: 10.1016/S0304-3940(02)01439-8
2002
Journal Article
Activation of NMDA receptors and L-type voltage-gated calcium channels mediates enhanced formation of Fyn-PSD95-NR2A complex after transient brain ischemia
Hou, Xiao-Yu, Zhang, Guang-Yi, Yan, Jing-Zhi, Chen, Min and Liu, Yong (2002). Activation of NMDA receptors and L-type voltage-gated calcium channels mediates enhanced formation of Fyn-PSD95-NR2A complex after transient brain ischemia. Brain Research, 955 (1-2), 123-132. doi: 10.1016/S0006-8993(02)03376-0
Funding
Past funding
Supervision
Availability
- Dr Min Chen is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Danger Signalling, Traumatic Brain Injury and Epileptogenesis
Associate Advisor
Media
Enquiries
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