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2024 Journal Article The burden and contemporary epidemiology of sepsis in childrenWatson, R. Scott, Carrol, Enitan D., Carter, Michael J., Kissoon, Niranjan, Ranjit, Suchitra and Schlapbach, Luregn J. (2024). The burden and contemporary epidemiology of sepsis in children. The Lancet Child and Adolescent Health, 8 (9), 670-681. doi: 10.1016/S2352-4642(24)00140-8 |
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2024 Journal Article Susceptibility to childhood sepsis, contemporary management, and future directionsCarter, Michael J., Carrol, Enitan D., Ranjit, Suchitra, Mozun, Rebeca, Kissoon, Niranjan, Watson, R. Scott and Schlapbach, Luregn J. (2024). Susceptibility to childhood sepsis, contemporary management, and future directions. The Lancet Child and Adolescent Health, 8 (9), 682-694. doi: 10.1016/S2352-4642(24)00141-X |
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2024 Journal Article The authors reply:Raman, Sainath, Gibbons, Kristen, LeMarsney, Renate and Schlapbach, Luregn J. (2024). The authors reply:. Pediatric Critical Care Medicine, 25 (9), e398-e399. doi: 10.1097/pcc.0000000000003578 |
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2024 Journal Article Quality improvement programmes in paediatric sepsis from a global perspectivede Souza, Daniela C., Paul, Raina, Mozun, Rebeca, Sankar, Jhuma, Jabornisky, Roberto, Lim, Emma, Harley, Amanda, Al Amri, Samirah, Aljuaid, Maha, Qian, Suyun, Schlapbach, Luregn J., Argent, Andrew and Kissoon, Niranjan (2024). Quality improvement programmes in paediatric sepsis from a global perspective. The Lancet Child and Adolescent Health, 8 (9), 695-706. doi: 10.1016/S2352-4642(24)00142-1 |
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2024 Journal Article Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the worldSanchez-Pinto, L. Nelson, del Pilar Arias López, María, Scott, Halden, Gibbons, Kristen, Moor, Michael, Watson, R. Scott, Wiens, Matthew O., Schlapbach, Luregn J. and Bennett, Tellen D. (2024). Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world. The Lancet Digital Health, 6 (9), e651-e661. doi: 10.1016/s2589-7500(24)00141-9 |
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2024 Journal Article Sex differences in pediatric sepsis—a systematic review protocolKennedy, Uchenna, Moulin, Juliette, Schlapbach, Luregn J., Menon, Kusum, Lee, Jan Hau and Held, Ulrike (2024). Sex differences in pediatric sepsis—a systematic review protocol. Systematic Reviews, 13 (1) 214, 1-5. doi: 10.1186/s13643-024-02631-z |
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2024 Journal Article Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent mannerGiannoni, Eric, Sanchez Sanchez, Guillem, Verdebout, Isoline, Papadopoulou, Maria, Rezwani, Moosa, Ahmed, Raya, Ladell, Kristin, Miners, Kelly L., McLaren, James E., Fraser, Donald J., Price, David A., Eberl, Matthias, Agyeman, Philipp K. A., Schlapbach, Luregn J and Vermijlen, David (2024). Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner. European Journal of Immunology, 54 (10) 2451190. doi: 10.1002/eji.202451190 |
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2024 Journal Article Antibiotic exposure of critically ill children at a tertiary care paediatric intensive care unit in SwitzerlandFenner, Anica, Huber, Melanie, Gotta, Verena, Jaeggi, Vera, Schlapbach, Luregn J. and Baumann, Philipp (2024). Antibiotic exposure of critically ill children at a tertiary care paediatric intensive care unit in Switzerland. Children, 11 (6) 731. doi: 10.3390/children11060731 |
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2024 Journal Article The quest for evidence on time to antibiotics in children with sepsis—finding the sweet spotLuethi, Nora, Schlapbach, Luregn J. and Baumann, Philipp (2024). The quest for evidence on time to antibiotics in children with sepsis—finding the sweet spot. JAMA Network Open, 7 (6) e2413926. doi: 10.1001/jamanetworkopen.2024.13926 |
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2024 Journal Article Pediatric Phoenix Sepsis Score validation challenges in low-resource settings and in the ED—ReplyWatson, R. Scott, Schlapbach, Luregn J., Sorce, Lauren R. and for the Society of Critical Care Medicine Pediatric Sepsis Definitions Task Force (2024). Pediatric Phoenix Sepsis Score validation challenges in low-resource settings and in the ED—Reply. JAMA, 331 (24), E1-E1. doi: 10.1001/jama.2024.8447 |
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2024 Journal Article Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort studySchlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8 |
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2024 Journal Article Plasma protein biomarkers distinguish multisystem inflammatory syndrome in children from other pediatric infectious and inflammatory diseasesYeoh, Sophya, Estrada-Rivadeneyra, Diego, Jackson, Heather, Keren, Ilana, Galassini, Rachel, Cooray, Samantha, Shah, Priyen, Agyeman, Philipp, Basmaci, Romain, Carrol, Enitan, Emonts, Marieke, Fink, Colin, Kuijpers, Taco, Martinon-Torres, Federico, Mommert-Tripon, Marine, Paulus, Stephane, Pokorn, Marko, Rojo, Pablo, Romani, Lorenza, Schlapbach, Luregn, Schweintzger, Nina, Shen, Ching-Fen, Tsolia, Maria, Usuf, Effua, van der Flier, Michiel, Vermont, Clementien, von Both, Ulrich, Yeung, Shunmay, Zavadska, Dace ... DIAMONDS and UK KD Genetic Consortia (2024). Plasma protein biomarkers distinguish multisystem inflammatory syndrome in children from other pediatric infectious and inflammatory diseases. Pediatric Infectious Disease Journal, 43 (5), 444-53. doi: 10.1097/inf.0000000000004267 |
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2024 Journal Article Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in SwitzerlandSchöbi, Nina, Sanchez, Carlos, Welzel, Tatjana, Bamford, Alasdair, Webb, Kate, Rojo, Pablo, Tremoulet, Adriana, Atkinson, Andrew, Schlapbach, Luregn J. and Bielicki, Julia Anna (2024). Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland. BMJ Open, 14 (4) e078137, 1-8. doi: 10.1136/bmjopen-2023-078137 |
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2024 Journal Article Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsisKhan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Irwin, Adam (RSG member), Phillips, Natalie (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768 |
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2024 Journal Article Fluid management and active fluid removal practices: a global survey of paediatric critical care physiciansAramburo, Angela, Raman, Sainath, Silversides, Jonathan A., Schlapbach, Luregn J., Gibbons, Kristen S., Ramnarayan, Padmanabhan, on behalf of the Australian, New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), the United Kingdom Paediatric Critical Care Society Study Group (PCCS-SG), Pellegrini, Breanna, George, Shane, Balit, Corrine, Oberender, Felix, Erickson, Simon, Flores, Jenipher Chumbes, Charles, Karina, Waak, Michaela, Long, Debbie, Butt, Warwick, Delzoppo, Carmel, Gelbart, Ben, Masterson, Kate, Millar, Johnny, Ganeshalingam, Anusha, Sherring, Claire, Singh, Puneet, Smith, Vicky, Schults, Jessica, Darvas, Jennifer and Festa, Marino (2024). Fluid management and active fluid removal practices: a global survey of paediatric critical care physicians. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 16, 1-16. doi: 10.1007/s44253-024-00038-1 |
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2024 Journal Article A Critique of the “Conservative Versus Liberal Oxygenation Targets in Critically Ill Children” Multicenter, Randomized Clinical Trial Published in the Lancet 2024—More on “Less Is More?”Mozun, Rebeca and Schlapbach, Luregn J. (2024). A Critique of the “Conservative Versus Liberal Oxygenation Targets in Critically Ill Children” Multicenter, Randomized Clinical Trial Published in the Lancet 2024—More on “Less Is More?”. Pediatric Critical Care Medicine, 25 (7), e338-e342. doi: 10.1097/pcc.0000000000003519 |
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2024 Journal Article Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsisChai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9 |
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2024 Journal Article Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudyvan Loon, Kim, Koomen, Erik, Hiensch, Senna, van Belle- van Haaren, Nicole J. C. W., Koelhuis-Faber, Mizja, Charlier, Jean-Luc, Lammers, Jan, Imhof, Oscar, Nijman, Joppe, van Wijk, Abraham, Breur, Johannes M. P. J., Gibbons, Kristen, Butt, Warwick, Schlapbach, Luregn J., Horton, Stephen, Korporaal, Suzanne and the NITRIC Study Group (2024). Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudy. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 13. doi: 10.1007/s44253-024-00037-2 |
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2024 Journal Article Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across EuropeKolberg, Laura, Khanijau, Aakash, van der Velden, Fabian J S, Herberg, Jethro, De, Tisham, Galassini, Rachel, Cunnington, Aubrey J, Wright, Victoria, Shah, Priyen, Kaforou, Myrsini, Wilson, Clare, Kuijpers, Taco, Martinón-Torres, Federico, Rivero-Calle, Irene, Moll, Henriette, Vermont, Clementien, Pokorn, Marko, Kolnik, Mojca, Pollard, Andrew J, Agyeman, Philipp K A, Schlapbach, Luregn J, Tsolia, Maria N, Yeung, Shunmay, Zavadska, Dace, Zenz, Werner, Schweintzger, Nina A, van der Flier, Michiel, de Groot, Ronald, Usuf, Effua ... The PERFORM Consortium (2024). Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe. Clinical Infectious Diseases, 78 (3), 526-534. doi: 10.1093/cid/ciad615 |
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2024 Journal Article Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsisChai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 539-547. doi: 10.1007/s00134-024-07353-3 |
