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2024 Journal Article Intravenous maintenance fluid therapy in acutely and critically ill children: state of the evidenceBrossier, David W., Goyer, Isabelle, Verbruggen, Sascha C. A. T., Jotterand Chaparro, Corinne, Rooze, Shancy, Marino, Luise V., Schlapbach, Luregn J., Tume, Lyvonne N. and Valla, Frederic V. (2024). Intravenous maintenance fluid therapy in acutely and critically ill children: state of the evidence. The Lancet Child and Adolescent Health, 8 (3), 236-244. doi: 10.1016/s2352-4642(23)00288-2 |
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2024 Journal Article International consensus criteria for pediatric sepsis and septic shockSchlapbach, Luregn J., Watson, R. Scott, Sorce, Lauren R., Argent, Andrew C., Menon, Kusum, Hall, Mark W., Akech, Samuel, Albers, David J., Alpern, Elizabeth R., Balamuth, Fran, Bembea, Melania, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Dewitt, Peter E., Evans, Idris, Flauzino De Oliveira, Cláudio, Horvat, Christopher M., Inwald, David, Ishimine, Paul, Jaramillo-Bustamante, Juan Camilo, Levin, Michael, Lodha, Rakesh, Martin, Blake, Nadel, Simon, Nakagawa, Satoshi, Peters, Mark J., Randolph, Adrienne G. ... Bennett, Tellen D. (2024). International consensus criteria for pediatric sepsis and septic shock. JAMA, 331 (8), 665-674. doi: 10.1001/jama.2024.0179 |
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2024 Journal Article Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trialHarley, Amanda, George, Shane, Phillips, Natalie, King, Megan, Long, Debbie, Keijzers, Gerben, Lister, Paula, Raman, Sainath, Bellomo, Rinaldo, Gibbons, Kristen, Schlapbach, Luregn J. and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform Study in the Emergency Department (RESPOND ED) Study Group (2024). Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial. Pediatric Critical Care Medicine, 25 (2), 106-117. doi: 10.1097/PCC.0000000000003351 |
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2024 Journal Article Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot studySchlapbach, Luregn J., Raman, Sainath, Buckley, David, George, Shane, King, Megan, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Erickson, Simon, Singh, Puneet, Festa, Marino, Gibbons, Kristen, Bellomo, Rinaldo and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform in the Paediatric Intensive Care Unit (RESPOND PICU) Study Investigators and the Australian and New Zealand Intensive Care Society Paediatric Study Group (2024). Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study. Pediatric Critical Care Medicine, 25 (2), 159-170. doi: 10.1097/PCC.0000000000003346 |
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2024 Journal Article Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort studyMcWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J., on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators, Irwin, Adam (RAPIDS member) and Bialasiewicz, Seweryn (RAPIDS member) (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349 |
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2024 Journal Article COVID-19 vaccine acceptance among parents of children with multisystem inflammatory syndrome in childrenBlanchard-Rohner, Geraldine, Sanchez, Carlos, Andre, Maya C., Bressieux-Degueldre, Sabrina, Grazioli, Serge, Perez, Marie-Helene, Wütz, Daniela, Schöbi, Nina, Welzel, Tatjana, Atkinson, Andrew, Schlapbach, Luregn J., Bielicki, Julia A., Trück, Johannes and for the Swissped RECOVERY Trial Group (2024). COVID-19 vaccine acceptance among parents of children with multisystem inflammatory syndrome in children. Pediatric Infectious Disease Journal, 43 (4), 361-364. doi: 10.1097/inf.0000000000004206 |
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2024 Journal Article Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsisHarris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology Spectrum, 12 (2) e0306523, 1-16. doi: 10.1128/spectrum.03065-23 |
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2024 Journal Article Correction: Neonatal sepsis definitions from randomised clinical trials (Pediatric Research, (2023), 93, 5, (1141-1148), 10.1038/s41390-021-01749-3)Hayes, Rían, Hartnett, Jack, Semova, Gergana, Murray, Cian, Murphy, Katherine, Carroll, Leah, Plapp, Helena, Hession, Louise, O’Toole, Jonathan, McCollum, Danielle, Roche, Edna, Jenkins, Elinor, Mockler, David, Hurley, Tim, McGovern, Matthew, Allen, John, Meehan, Judith, Plötz, Frans B., Strunk, Tobias, de Boode, Willem P., Polin, Richard, Wynn, James L., Degtyareva, Marina, Küster, Helmut, Janota, Jan, Giannoni, Eric, Schlapbach, Luregn J., Keij, Fleur M., Reiss, Irwin K. M. ... Molloy, Eleanor J. (2024). Correction: Neonatal sepsis definitions from randomised clinical trials (Pediatric Research, (2023), 93, 5, (1141-1148), 10.1038/s41390-021-01749-3). Pediatric Research, 96 (7), 1882-1882. doi: 10.1038/s41390-024-03416-9 |
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2024 Journal Article Development and validation of the Phoenix criteria for pediatric sepsis and septic shockSanchez-Pinto, L. Nelson, Bennett, Tellen D., Dewitt, Peter E., Russell, Seth, Rebull, Margaret N., Martin, Blake, Akech, Samuel, Albers, David J., Alpern, Elizabeth R., Balamuth, Fran, Bembea, Melania, Chisti, Mohammod Jobayer, Evans, Idris, Horvat, Christopher M., Jaramillo-Bustamante, Juan Camilo, Kissoon, Niranjan, Menon, Kusum, Scott, Halden F., Weiss, Scott L., Wiens, Matthew O., Zimmerman, Jerry J., Argent, Andrew C., Sorce, Lauren R., Schlapbach, Luregn J., Watson, R. Scott, Biban, Paolo, Carrol, Enitan, Chiotos, Kathleen, Flauzino De Oliveira, Claudio ... Wynn, James L. (2024). Development and validation of the Phoenix criteria for pediatric sepsis and septic shock. JAMA, 331 (8), 675-686. doi: 10.1001/jama.2024.0196 |
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2024 Journal Article Cardiac assessment and inflammatory markers in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV2 (PIMS-TS) treated with methylprednisolone versus intravenous immunoglobulins: 6-month follow-up outcomes of the randomised controlled Swissped RECOVERY trialAndre, Maya C., Sanchez, Carlos, Bressieux-Degueldre, Sabrina, Perez, Marie-Helene, Wütz, Daniela, Blanchard-Rohner, Geraldine, Grazioli, Serge, Schöbi, Nina, Trück, Johannes, Welzel, Tatjana, Atkinson, Andrew, Schlapbach, Luregn J., Bielicki, Julia, Andre, Maya C., Sanchez, Carlos, Bressieux-Degueldre, Sabrina, Perez, Marie-Helene, Wütz, Daniela, Blanchard-Rohner, Geraldine, Grazioli, Serge, Schöbi, Nina, Trück, Johannes, Welzel, Tatjana, Atkinson, Andrew, Schlapbach, Luregn J., Bielicki, Julia, Koehler, Henrik, Gysi, Spyridoula, Janz, Indra ... Faust, Saul N. (2024). Cardiac assessment and inflammatory markers in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV2 (PIMS-TS) treated with methylprednisolone versus intravenous immunoglobulins: 6-month follow-up outcomes of the randomised controlled Swissped RECOVERY trial. eClinicalMedicine, 67 102358. doi: 10.1016/j.eclinm.2023.102358 |
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2024 Journal Article Organ dysfunction in children with blood culture-proven sepsis: comparative performance of four scores in a national cohort studySchlapbach, Luregn J., Goertz, Sabrina, Hagenbuch, Niels, Aubert, Blandine, Papis, Sebastien, Giannoni, Eric, Posfay-Barbe, Klara M., Stocker, Martin, Heininger, Ulrich, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Natalucci, Giancarlo, Relly, Christa, Riedel, Thomas, Aebi, Christoph, Berger, Christoph, Agyeman, Philipp K. A. and for the Swiss Pediatric Sepsis Study Group (2024). Organ dysfunction in children with blood culture-proven sepsis: comparative performance of four scores in a national cohort study. Pediatric Critical Care Medicine, 25 (3), e117-e128. doi: 10.1097/pcc.0000000000003388 |
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2023 Journal Article Biobanking and consenting to research: a qualitative thematic analysis of young people’s perspectives in the North East of Englandvan der Velden, Fabian J. S., Lim, Emma, Gills, Lily, Broadey, Jasmin, Hayes, Louise, Roberts, Eve, Courtney, Jack, Ball, Joanne, Herberg, Jethro, Galassini, Rachel, Emonts, Marieke, Levin, Michael, Cunnington, Aubrey, Kaforou, Myrsini, Wright, Victoria, Bellos, Evangelos, Broderick, Claire, Channon-Wells, Samuel, Cooray, Samantha, De, Tisham, D’Souza, Giselle, Elorrieta, Leire Estramiana, Estrada-Rivadeneyra, Diego, Habgood-Coote, Dominic, Hamilton, Shea, Jackson, Heather, Kavanagh, James, Marjaneh, Mahdi Moradi, Nichols, Samuel ... Ndure, Momodou (2023). Biobanking and consenting to research: a qualitative thematic analysis of young people’s perspectives in the North East of England. BMC Medical Ethics, 24 (1) 47. doi: 10.1186/s12910-023-00925-w |
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2023 Journal Article REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1)Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J. and Gibbons, Kristen S. (2023). REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1). BMJ Open, 13 (11) e076460, 1-8. doi: 10.1136/bmjopen-2023-076460 |
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2023 Journal Article A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning studyJackson, Heather R., Zandstra, Judith, Menikou, Stephanie, Hamilton, Melissa Shea, McArdle, Andrew J., Fischer, Roman, Thorne, Adam M., Huang, Honglei, Tanck, Michael W., Jansen, Machiel H., De, Tisham, Agyeman, Philipp K A, Von Both, Ulrich, Carrol, Enitan D., Emonts, Marieke, Eleftheriou, Irini, Van der Flier, Michiel, Fink, Colin, Gloerich, Jolein, De Groot, Ronald, Moll, Henriette A., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J. (PERFORM consortium), Tsolia, Maria N., Usuf, Effua, Wright, Victoria J., Yeung, Shunmay, Zavadska, Dace ... Kaforou, Myrsini (2023). A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study. The Lancet. Digital health, 5 (11), e774-e785. doi: 10.1016/S2589-7500(23)00149-8 |
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2023 Journal Article Avoid re-interpreting fluid bolus recommendations for low-income settings – Authors’ replyRanjit, Suchitra, Kissoon, Niranjan, Argent, Andrew, Inwald, David, Ventura, Andréa Maria Cordeiro, Jaborinsky, Roberto, Sankar, Jhuma, Carla de Souza, Daniela, Natraj, Rajeswari, Flauzino De Oliveira, Claudio, Samransamruajkit, Rujipat, Jayashree, Muralidharan and Schlapbach, Luregn J (2023). Avoid re-interpreting fluid bolus recommendations for low-income settings – Authors’ reply. The Lancet Child and Adolescent Health, 7 (11), e19-E19. doi: 10.1016/S2352-4642(23)00258-4 |
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2023 Journal Article Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective studyWösten-van Asperen, Roelie M., la Roi-Teeuw, Hannah M., van Amstel, Rombout BE., Bos, Lieuwe DJ., Tissing, Wim JE., Jordan, Iolanda, Dohna-Schwake, Christian, Bottari, Gabriella, Pappachan, John, Crazzolara, Roman, Comoretto, Rosanna I., Mizia-Malarz, Agniezka, Moscatelli, Andrea, Sánchez-Martín, María, Willems, Jef, Rogerson, Colin M., Bennett, Tellen D., Luo, Yuan, Atreya, Mihir R., Faustino, E.Vincent S., Geva, Alon, Weiss, Scott L., Schlapbach, Luregn J., Sanchez-Pinto, L Nelson, Caballero, Marina, Margarit, Adriana, Campos, Roi, Möller, Paula, Serpe, Carmela ... Stroup, Emily (2023). Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective study. eClinicalMedicine, 65 102252, 102252. doi: 10.1016/j.eclinm.2023.102252 |
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2023 Journal Article Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative studyJimenez-Zambrano, Andrea, Ritger, Carly, Rebull, Margaret, Wiens, Matthew O., Kabajaasi, Olive, Jaramillo-Bustamante, Juan Camilo, Argent, Andrew C., Kissoon, Niranjan, Schlapbach, Luregn J., Sorce, Lauren R., Watson, R Scott, Dorsey Holliman, Brooke, Sanchez-Pinto, Lazaro N. and Bennett, Tellen D. (2023). Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative study. BMJ open, 13 (10) e074458, 1-9. doi: 10.1136/bmjopen-2023-074458 |
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2023 Journal Article Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signatureHabgood-Coote, Dominic, Wilson, Clare, Shimizu, Chisato, Barendregt, Anouk M., Philipsen, Ria, Galassini, Rachel, Calle, Irene Rivero, Workman, Lesley, Agyeman, Philipp K.A., Ferwerda, Gerben, Anderson, Suzanne T., van den Berg, J. Merlijn, Emonts, Marieke, Carrol, Enitan D., Fink, Colin G., de Groot, Ronald, Hibberd, Martin L., Kanegaye, John, Nicol, Mark P., Paulus, Stéphane, Pollard, Andrew J., Salas, Antonio, Secka, Fatou, Schlapbach, Luregn J., Tremoulet, Adriana H., Walther, Michael, Zenz, Werner, Van der Flier, Michiel, Zar, Heather J. ... Kaforou, Myrsini (2023). Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature. Med, 4 (9), 635-654.e5. doi: 10.1016/j.medj.2023.06.007 |
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2023 Journal Article Adaptive clinical trials in pediatric critical care: a systematic reviewGilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273 |
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2023 Journal Article Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational studyShah, Priyen, Voice, Marie, Calvo-Bado, Leonides, Rivero-Calle, Irene, Morris, Sophie, Nijman, Ruud, Broderick, Claire, De, Tisham, Eleftheriou, Irini, Galassini, Rachel, Khanijau, Aakash, Kolberg, Laura, Kolnik, Mojca, Rudzate, Aleksandra, Sagmeister, Manfred G., Schweintzger, Nina A., Secka, Fatou, Thakker, Clare, van der Velden, Fabian, Vermont, Clementien, Vincek, Katarina, Agyeman, Philipp K.A., Cunnington, Aubrey J., De Groot, Ronald, Emonts, Marieke, Fidler, Katy, Kuijpers, Taco W., Mommert-Tripon, Marine, Brengel-Pesce, Karen ... Geissler, J. (2023). Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study. The Lancet Regional Health - Europe, 32 100682, 100682. doi: 10.1016/j.lanepe.2023.100682 |
