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2022

Journal Article

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations

Kumar, Vikrant, Pouw, Richard B., Autio, Matias I., Sagmeister, Manfred G., Phua, Zai Yang, Borghini, Lisa, Wright, Victoria J., Hoggart, Clive, Pan, Bangfen, Tan, Antson Kiat Yee, Binder, Alexander, Brouwer, Mieke C., Pinnock, Ellie, De Groot, Ronald, Hazelzet, Jan, Emonts, Marieke, Van Der Flier, Michiel, Reiter, Karl, Nöthen, Markus M., Hoffmann, Per, Schlapbach, Luregn J., Bellos, Evangelos, Anderson, Suzanne, Secka, Fatou, Martinón-Torres, Federico, Salas, Antonio, Fink, Colin, Carrol, Enitan D., Pollard, Andrew J. ... Davila, Sonia (2022). Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations. American Journal of Human Genetics, 109 (9), 1680-1691. doi: 10.1016/j.ajhg.2022.08.001

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations

2022

Journal Article

Correction to: Intravenous maintenance fluid therapy practice in the pediatric acute and critical care settings: a European and Middle Eastern survey (European Journal of Pediatrics, (2022), 181, 8, (3163-3172), 10.1007/s00431-022-04467-y)

Morice, Claire, Alsohime, Fahad, Mayberry, Huw, Tume, Lyvonne N., Brossier, David, Valla, Frederic V., Didier, Capucine, Moullet, Clémence, Jotterand Chaparro, Corinne, Kühlwein, Eva, Chiusolo, Fabrizio, Porcheret, Florence, Mehmeti, Fortesa, Tekguc, Hakan, Ilia, Stavroula, Goyer, Isabelle, Lopez-Herce, Jesus, Pappachan, John, Lopez, Jorge, Tziouvas, Konstantinos, Costa, Leonardo, Boto, Leonor Reis, Marino, Luise, Schlapbach, Luregn J, Mierzewska-Schmidt, Magdalena, Minambres, Maria, Kneyber, Martin, Fae, Monica, Joram, Nyandat ... Beldjilali, Sophie (2022). Correction to: Intravenous maintenance fluid therapy practice in the pediatric acute and critical care settings: a European and Middle Eastern survey (European Journal of Pediatrics, (2022), 181, 8, (3163-3172), 10.1007/s00431-022-04467-y). European Journal of Pediatrics, 181 (8), 3173-3173. doi: 10.1007/s00431-022-04513-9

Correction to: Intravenous maintenance fluid therapy practice in the pediatric acute and critical care settings: a European and Middle Eastern survey (European Journal of Pediatrics, (2022), 181, 8, (3163-3172), 10.1007/s00431-022-04467-y)

2022

Journal Article

Antimicrobial stewardship programs in European pediatric intensive care units: an international survey of practices

Clos, Maité, Schlapbach, Luregn J., Arata-Bardet, Julie, Javouhey, Etienne and Mortamet, Guillaume (2022). Antimicrobial stewardship programs in European pediatric intensive care units: an international survey of practices. European Journal of Pediatrics, 181 (7), 2873-2877. doi: 10.1007/s00431-022-04481-0

Antimicrobial stewardship programs in European pediatric intensive care units: an international survey of practices

2022

Journal Article

Resuscitating children with sepsis and impaired perfusion with maintenance fluids: an evolving concept

Schlapbach, Luregn J. and Kissoon, Niranjan (2022). Resuscitating children with sepsis and impaired perfusion with maintenance fluids: an evolving concept. Pediatric Critical Care Medicine, 23 (7), 563-565. doi: 10.1097/PCC.0000000000002990

Resuscitating children with sepsis and impaired perfusion with maintenance fluids: an evolving concept

2022

Journal Article

Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (DAISY): pilot study protocol

Long, Debbie, Gibbons, Kristen, Dow, Belinda, Best, James, Webb, Kerri-Lyn, Liley, Helen G., Stocker, Christian, Thoms, Debra, Schlapbach, Luregn J., Wharton, Carolyn, Lister, Paula, Matuschka, Lori, Castillo, Maria Isabel, Tyack, Zephanie and Bora, Samudragupta (2022). Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (DAISY): pilot study protocol. BMJ Open, 12 (7) e060714, 1-11. doi: 10.1136/bmjopen-2021-060714

Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (DAISY): pilot study protocol

2022

Journal Article

Prediction of recovery from multiple organ dysfunction syndrome in pediatric sepsis patients

Fan, Bowen, Klatt, Juliane, Moor, Michael M., Daniels, Latasha A., Sanchez-Pinto, Lazaro N., Agyeman, Philipp K. A., Schlapbach, Luregn J. and Borgwardt, Karsten M. (2022). Prediction of recovery from multiple organ dysfunction syndrome in pediatric sepsis patients. Bioinformatics, 38 (Supplement 1), I101-I108. doi: 10.1093/bioinformatics/btac229

Prediction of recovery from multiple organ dysfunction syndrome in pediatric sepsis patients

2022

Journal Article

Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial

Schlapbach, Luregn J., Gibbons, Kristen S., Horton, Stephen B., Johnson, Kerry, Long, Debbie A., Buckley, David H. F., Erickson, Simon, Festa, Marino, D'Udekem, Yves, Alphonso, Nelson, Winlaw, David S., Delzoppo, Carmel, Van Loon, Kim, Jones, Mark, Young, Paul J., Butt, Warwick and Schibler, Andreas (2022). Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial. JAMA: Journal of the American Medical Association, 328 (1), 38-47. doi: 10.1001/jama.2022.9376

Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial

2022

Journal Article

Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia

Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6

Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia

2022

Journal Article

The current and future state of pediatric sepsis definitions: an international survey

Morin, Luc, Hall, Mark, de Souza, Daniela, Guoping, Lu, Jabornisky, Roberto, Shime, Nobuaki, Ranjit, Suchitra, Gilholm, Patricia, Nakagawa, Satoshi, Zimmerman, Jerry J., Sorce, Lauren R., Argent, Andrew, Kissoon, Niranjan, Tissières, Pierre, Watson, R. Scott and Schlapbach, Luregn J (2022). The current and future state of pediatric sepsis definitions: an international survey. Pediatrics, 149 (6) e2021052565. doi: 10.1542/peds.2021-052565

The current and future state of pediatric sepsis definitions: an international survey

2022

Journal Article

Multicenter randomized trial of methylprednisolone vs. intravenous immunoglobulins to treat the pediatric inflammatory multisystem syndrome—temporally associated with SARS-CoV-2 (PIMS-TS): protocol of the Swissped RECOVERY Trial

Welzel, Tatjana, Schöbi, Nina, André, Maya C., Bailey, Douggl G. N., Blanchard-Rohner, Geraldine, Buettcher, Michael, Grazioli, Serge, Koehler, Henrik, Perez, Marie-Helene, Trück, Johannes, Vanoni, Federica, Zimmermann, Petra, Atkinson, Andrew, Sanchez, Carlos, Whittaker, Elizabeth, Faust, Saul N., Bielicki, Julia A. and Schlapbach, Luregn J. (2022). Multicenter randomized trial of methylprednisolone vs. intravenous immunoglobulins to treat the pediatric inflammatory multisystem syndrome—temporally associated with SARS-CoV-2 (PIMS-TS): protocol of the Swissped RECOVERY Trial. Frontiers in Pediatrics, 10 905046, 1-12. doi: 10.3389/fped.2022.905046

Multicenter randomized trial of methylprednisolone vs. intravenous immunoglobulins to treat the pediatric inflammatory multisystem syndrome—temporally associated with SARS-CoV-2 (PIMS-TS): protocol of the Swissped RECOVERY Trial

2022

Journal Article

Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study

Equey, Lucile, Agyeman, Philipp K. A., Veraguth, Rosemarie, Rezzi, Serge, Schlapbach, Luregn J. and Giannoni, Eric (2022). Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study. Pediatric Critical Care Medicine, 23 (5), 390-394. doi: 10.1097/PCC.0000000000002911

Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study

2022

Journal Article

Time to tackle early-onset sepsis in low-income and middle-income countries

Schlapbach, Luregn J, Hagmann, Cornelia and Giannoni, Eric (2022). Time to tackle early-onset sepsis in low-income and middle-income countries. The Lancet Global Health, 10 (5), e592-e593. doi: 10.1016/S2214-109X(22)00086-9

Time to tackle early-onset sepsis in low-income and middle-income countries

2022

Journal Article

Endothelial damage in sepsis: the importance of systems biology

Fernández-Sarmiento, Jaime, Schlapbach, Luregn J., Acevedo, Lorena, Santana, Carolina Ramírez, Acosta, Yeny, Diana, Ampudia, Monsalve, M. and Carcillo, Joseph A. (2022). Endothelial damage in sepsis: the importance of systems biology. Frontiers in Pediatrics, 10 828968, 828968. doi: 10.3389/fped.2022.828968

Endothelial damage in sepsis: the importance of systems biology

2022

Journal Article

Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis

Stocker, Martin, Daunhawer, Imant, Van Herk, Wendy, El Helou, Salhab, Dutta, Sourabh, Schuerman, Frank A. B. A., Van Den Tooren-De Groot, Rita K., Wieringa, Jantien W., Janota, Jan, Van Der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., De Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., De Mol, Amerik C., Hoffmann-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., Van Gijsel, Juliette, Plötz, Frans B., Wellmann, Sven, Achten, Niek B., Lehnick, Dirk, Van Rossum, Annemarie M. C. and Vogt, Julia E. (2022). Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis. Pediatric Infectious Disease Journal, 41 (3), 248-254. doi: 10.1097/INF.0000000000003344

Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis

2022

Journal Article

Educational outcomes of childhood survivors of critical illness—A population-based linkage study

Tomaszewski, Wojtek, Ablaza, Christine, Straney, Lahn, Taylor, Catherine, Millar, Johnny, Schlapbach, Luregn and on behalf of the Australian & New Zealand Intensive Care Society (ANZICS) Centre for Outcomes & Resource Evaluation (CORE) and the Australian & New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2022). Educational outcomes of childhood survivors of critical illness—A population-based linkage study. Critical Care Medicine, 50 (6), 901-912. doi: 10.1097/CCM.0000000000005461

Educational outcomes of childhood survivors of critical illness—A population-based linkage study

2022

Journal Article

Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial

McBride, Craig Antony, Rahiman, Sarfaraz, Schlapbach, Luregn J., Schults, Jessica A., Kleidon, Tricia M., Kennedy, Melanie, Paterson, Rebecca S., Byrnes, Joshua, Ware, Robert S. and Ullman, Amanda Judith (2022). Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial. BMJ Open, 12 (2) e047765, e047765. doi: 10.1136/bmjopen-2020-047765

Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial

2022

Journal Article

Understanding detrimental host response to infection: the promise of transcriptomics

Schlapbach, Luregn J and Coin, Lachlan (2022). Understanding detrimental host response to infection: the promise of transcriptomics. Pediatric critical care medicine, 23 (2), 133-135. doi: 10.1097/PCC.0000000000002870

Understanding detrimental host response to infection: the promise of transcriptomics

2022

Journal Article

Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce

Menon, Kusum, Schlapbach, Luregn J., Akech, Samuel, Argent, Andrew, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Evans, Idris V. R., Inwald, David P., Ishimine, Paul, Kissoon, Niranjan, Lodha, Rakesh, Nadel, Simon, Oliveira, Cláudio Flauzino, Peters, Mark, Sadeghirad, Benham, Scott, Halden F., De Souza, Daniela C., Tissieres, Pierre, Watson, R. Scott, Wiens, Matthew O., Wynn, James L., Zimmerman, Jerry J. and Sorce, Lauren R. (2022). Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce. Critical Care Medicine, 50 (1), 21-36. doi: 10.1097/CCM.0000000000005294

Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce

2022

Journal Article

Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

Slooff, Valerie, Hoogendoorn, Rianne, Nielsen, Jeppe Sylvest Angaard, Pappachan, John, Amigoni, Angela, Caramelli, Fabio, Aziz, Omer, Wildschut, Enno, Verbruggen, Sascha, Crazzolara, Roman, Dohna-Schwake, Christian, Potratz, Jenny, Willems, Jef, Llevadias, Judit, Moscatelli, Andrea, Montaguti, Alessia, Bottari, Gabriella, Di Nardo, Matteo, Schlapbach, Luregn, Wösten-van Asperen, Roelie and POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric Neonatal Intensive Care) (2022). Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies. Annals of Intensive Care, 12 (1) 8, 1-11. doi: 10.1186/s13613-022-00983-0

Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

2022

Journal Article

Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation

Doo, Irene, Staub, Lukas P., Mattke, Adrian, Haisz, Emma, Seidler, Anna Lene, Alphonso, Nelson and Schlapbach, Luregn J. (2022). Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation. Frontiers in Pediatrics, 9 824552, 824552. doi: 10.3389/fped.2021.824552

Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation