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2023 Journal Article SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in diseaseTapia del Fierro, Andres, den Hamer, Bianca, Benetti, Natalia, Jansz, Natasha, Chen, Kelan, Beck, Tamara, Vanyai, Hannah, Gurzau, Alexandra D., Daxinger, Lucia, Xue, Shifeng, Ly, Thanh Thao Nguyen, Wanigasuriya, Iromi, Iminitoff, Megan, Breslin, Kelsey, Oey, Harald, Krom, Yvonne D., van der Hoorn, Dinja, Bouwman, Linde F., Johanson, Timothy M., Ritchie, Matthew E., Gouil, Quentin A., Reversade, Bruno, Prin, Fabrice, Mohun, Timothy, van der Maarel, Silvère M., McGlinn, Edwina, Murphy, James M., Keniry, Andrew, de Greef, Jessica C. and Blewitt, Marnie E. (2023). SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease. Nature Communications, 14 (1) 5466, 1-22. doi: 10.1038/s41467-023-40992-6 |
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2023 Journal Article Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent neviMuse, Meghan E., Schaider, Helmut, Oey, Harald, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2023). Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi. Journal of Investigative Dermatology, 143 (9), 1830-1834. doi: 10.1016/j.jid.2023.03.1653 |
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2021 Journal Article The role of MORC3 in silencing transposable elements in mouse embryonic stem cellsDesai, Varsha P., Chouaref, Jihed, Wu, Haoyu, Pastor, William A., Kan, Ryan L., Oey, Harald M., Li, Zheng, Ho, Jamie, Vonk, Kelly K. D., San Leon Granado, David, Christopher, Michael A., Clark, Amander T., Jacobsen, Steven E. and Daxinger, Lucia (2021). The role of MORC3 in silencing transposable elements in mouse embryonic stem cells. Epigenetics and Chromatin, 14 (1) 49, 49. doi: 10.1186/s13072-021-00420-9 |
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2021 Journal Article Radiomics biomarkers correlate with CD8 expression and predict immune signatures in melanoma patientsAoude, Lauren G., Wong, Bernadette, Bonazzi, Vanessa F, Brosda, Sandra, Walters, Shaun B., Koufariotis, Lambros T., Naeini, Marjan M., Pearson, John V, Oey, Harald, Patel, Kalpana, Bradford, Julia J., Bloxham, Conor J, Atkinson, Victoria, Law, Phillip, Strutton, Geoffrey, Bayley, Gerard, Yang, Samuel, Smithers, B. Mark, Waddell, Nicola, Miles, Kenneth and Barbour, Andrew P. (2021). Radiomics biomarkers correlate with CD8 expression and predict immune signatures in melanoma patients. Molecular Cancer Research, 19 (6) molcanres.1038.2020, 950-956. doi: 10.1158/1541-7786.mcr-20-1038 |
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2021 Journal Article EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entityGandhi, Maher K., Hoang, Thanh, Law, Soi C., Brosda, Sandra, O'Rourke, Kacey, Tobin, Joshua W. D., Vari, Frank, Murigneux, Valentine, Fink, J. Lynn, Gunawardana, Jay, Gould, Clare M., Oey, Harald, Bednarska, Karolina, Delecluse, Susanne, Trappe, Ralf Ulrich, de Long, Lilia Merida, Sabdia, Muhammed Bilal, Bhagat, Govind, Hapgood, Greg, Blyth, Emily, Clancy, Leighton E., Wight, Joel, Hawkes, Eliza A., Rimsza, Lisa M., Maguire, Alanna, Bojarczuk, Kamil, Chapuy, Bjoern and Keane, Colm (2021). EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity. Blood, 137 (11), 1468-1477. doi: 10.1182/blood.2020008520 |
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Featured 2020 Journal Article Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patientsAoude, Lauren G., Bonazzi, Vanessa F., Brosda, Sandra, Patel, Kalpana, Koufariotis, Lambros T., Oey, Harald, Nones, Katia, Wood, Scott, Pearson, John V., Lonie, James M., Arneil, Melissa, Atkinson, Victoria, Smithers, B. Mark, Waddell, Nicola and Barbour, Andrew P. (2020). Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients. Scientific Reports, 10 (1) 17687, 17687. doi: 10.1038/s41598-020-74956-3 |
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2020 Journal Article Chromosome arm aneuploidies shape tumour evolution and drug responseShukla, Ankit, Nguyen, Thu H. M., Moka, Sarat B., Ellis, Jonathan J., Grady, John P., Oey, Harald, Cristino, Alexandre S., Khanna, Kum Kum, Kroese, Dirk P., Krause, Lutz, Dray, Eloise, Fink, J. Lynn and Duijf, Pascal H. G. (2020). Chromosome arm aneuploidies shape tumour evolution and drug response. Nature Communications, 11 (1) 449, 449. doi: 10.1038/s41467-020-14286-0 |
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2020 Journal Article Targeting an adenosine-mediated “don’t eat me signal” augments anti-lymphoma immunity by anti-CD20 monoclonal antibodyNakamura, Kyohei, Casey, Mika, Oey, Harald, Vari, Frank, Stagg, John, Gandhi, Maher K. and Smyth, Mark J. (2020). Targeting an adenosine-mediated “don’t eat me signal” augments anti-lymphoma immunity by anti-CD20 monoclonal antibody. Leukemia, 34 (10), 2708-2721. doi: 10.1038/s41375-020-0811-3 |
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2019 Journal Article Whole-genome sequencing of human malignant mesothelioma tumours and cell linesOey, Harald, Daniels, Marissa, Relan, Vandana, Chee, Tian Mun, Davidson, Morgan R., Yang, Ian A., Ellis, Jonathan J., Fong, Kwun M., Krause, Lutz and Bowman, Rayleen V. (2019). Whole-genome sequencing of human malignant mesothelioma tumours and cell lines. Carcinogenesis, 40 (6), 724-734. doi: 10.1093/carcin/bgz066 |
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2019 Journal Article Whole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobiumOey, Harald, Zakrzewski, Martha, Gravermann, Kerstin, Young, Neil D., Korhonen, Pasi K., Gobert, Geoffrey N., Nawaratna, Sujeevi, Hasan, Shihab, Martínez, David M., You, Hong, Lavin, Martin, Jones, Malcolm K., Ragan, Mark A., Stoye, Jens, Oleaga, Ana, Emery, Aidan M., Webster, Bonnie, Rollinson, David, Gasser, Robin B., McManus, Donald P. and Krause, Lutz (2019). Whole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobium. PLOS Pathogens, 15 (1) e1007513, e1007513. doi: 10.1371/journal.ppat.1007513 |
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2018 Journal Article Whole-genome sequence of the oriental lung fluke Paragonimus westermaniOey, Harald, Zakrzewski, Martha, Narain, Kanwar, Devi, K Rekha, Agatsuma, Takeshi, Nawaratna, Sujeevi, Gobart, Geoffrey, Jones, Malcolm, Ragan, Mark A, McManus, Donald P and Krause, Lutz (2018). Whole-genome sequence of the oriental lung fluke Paragonimus westermani. GigaScience, 8 (1). doi: 10.1093/gigascience/giy146 |
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2016 Journal Article Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinomaKrause, Lutz, Nones, Katia , Loffler, Kelly A., Nancarrow, Derek, Oey, Harald , Tang, Yue Hang, Wayte, Nicola J., Patch, Ann Marie, Patel, Kalpana , Brosda, Sandra, Manning, Suzanne, Lampe, Guy, Clouston, Andrew, Thomas, Janine, Stoye, Jens, Hussey, Damian J., Watson, David I., Lord, Reginald V., Phillips, Wayne A., Gotley, David, Smithers, B. Mark, Whiteman, David C., Hayward, Nicholas K., Grimmond, Sean M., Waddell, Nicola and Barbour, Andrew P. (2016). Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma. Carcinogenesis, 37 (4), 356-365. doi: 10.1093/carcin/bgw018 |
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2016 Journal Article Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouseIsbel, Luke, Prokopuk, Lexie, Wu, Haoyu, Daxinger, Lucia, Oey, Harald, Spurling, Alex, Lawther, Adam J., Hale, Matthew W. and Whitelaw, Emma (2016). Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse. eLife, 5 (JULY) e15082. doi: 10.7554/eLife.15082 |
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2016 Journal Article Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotypeDaxinger, Lucia, Oey, Harald, Isbel, Luke, Whitelaw, Nadia C., Youngson, Neil A., Spurling, Alex, Vonk, Kelly K. D. and Whitelaw, Emma (2016). Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype. Scientific Reports, 6 (1) 25004, e25004.1-e25004.10. doi: 10.1038/srep25004 |
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2015 Journal Article Genetic and epigenetic variation among inbred mouse littermates: Identification of inter-individual differentially methylated regionsOey, Harald, Isbel, Luke, Hickey, Peter, Ebaid, Basant and Whitelaw, Emma (2015). Genetic and epigenetic variation among inbred mouse littermates: Identification of inter-individual differentially methylated regions. Epigenetics and Chromatin, 8 (54) 47, 54. doi: 10.1186/s13072-015-0047-z |
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2015 Journal Article The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancersHarten, Sarah K., Oey, Harald, Bourke, Lauren M., Bharti, Vandhana, Isbel, Luke, Daxinger, Lucia, Faou, Pierre, Robertson, Neil, Matthews, Jacqueline M. and Whitelaw, Emma (2015). The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers. BMC Biology, 13 (21) 21, 1-15. doi: 10.1186/s12915-015-0128-2 |
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2015 Journal Article Identification of novel hypomorphic and null mutations in Klf1 derived from a genetic screen for modifiers of α-globin transgene variegationSorolla, Anabel, Tallack, Michael R., Oey, Harald, Harten, Sarah K., Daxinger, Lucia Clemens, Magor, Graham W., Combes, Alex N., Ilsley, Melissa, Whitelaw, Emma and Perkins, Andrew C. (2015). Identification of novel hypomorphic and null mutations in Klf1 derived from a genetic screen for modifiers of α-globin transgene variegation. Genomics, 105 (2), 116-122. doi: 10.1016/j.ygeno.2014.09.013 |
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2015 Journal Article Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host GenomeIsbel, Luke, Srivastava, Rahul, Oey, Harald, Spurling, Alex, Daxinger, Lucia, Puthalakath, Hamsa and Whitelaw, Emma (2015). Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. PLoS Genetics, 11 (12) e1005693, 1-25. doi: 10.1371/journal.pgen.1005693 |
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2014 Journal Article On the meaning of the word 'epimutation'Oey, H. and Whitelaw, E. (2014). On the meaning of the word 'epimutation'. Trends in Genetics, 30 (12), 519-520. doi: 10.1016/j.tig.2014.08.005 |
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2013 Journal Article An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouseDaxinger, Lucia, Harten, Sarah K., Oey, Harald, Epp, Trevor, Isbel, Luke, Huang, Edward, Whitelaw, Nadia, Apedaile, Anwyn, Sorolla, Anabel, Yong, Joan, Bharti, Vandhana, Sutton, Joanne, Ashe, Alyson, Pang, Zhenyi, Wallace, Nathan, Gerhardt, Daniel J., Blewitt, Marnie E., Jeddeloh, Jeffrey A. and Whitelaw, Emma (2013). An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biology, 14 (9) R96. doi: 10.1186/gb-2013-14-9-r96 |
