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2023 Journal Article SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in diseaseTapia del Fierro, Andres, den Hamer, Bianca, Benetti, Natalia, Jansz, Natasha, Chen, Kelan, Beck, Tamara, Vanyai, Hannah, Gurzau, Alexandra D., Daxinger, Lucia, Xue, Shifeng, Ly, Thanh Thao Nguyen, Wanigasuriya, Iromi, Iminitoff, Megan, Breslin, Kelsey, Oey, Harald, Krom, Yvonne D., van der Hoorn, Dinja, Bouwman, Linde F., Johanson, Timothy M., Ritchie, Matthew E., Gouil, Quentin A., Reversade, Bruno, Prin, Fabrice, Mohun, Timothy, van der Maarel, Silvère M., McGlinn, Edwina, Murphy, James M., Keniry, Andrew, de Greef, Jessica C. and Blewitt, Marnie E. (2023). SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease. Nature Communications, 14 (1) 5466, 1-22. doi: 10.1038/s41467-023-40992-6 |
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2023 Conference Publication Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent neviMuse, Meghan E., Schaider, Helmut, Oey, Harald, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2023). Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi. 114th Annual Meeting of the American Association for Cancer Research (AACR), Orlando Fl, Apr 14-19, 2023. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2023-6000 |
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2023 Journal Article Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent neviMuse, Meghan E., Schaider, Helmut, Oey, Harald, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2023). Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi. Journal of Investigative Dermatology, 143 (9), 1830-1834. doi: 10.1016/j.jid.2023.03.1653 |
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2021 Journal Article The role of MORC3 in silencing transposable elements in mouse embryonic stem cellsDesai, Varsha P., Chouaref, Jihed, Wu, Haoyu, Pastor, William A., Kan, Ryan L., Oey, Harald M., Li, Zheng, Ho, Jamie, Vonk, Kelly K. D., San Leon Granado, David, Christopher, Michael A., Clark, Amander T., Jacobsen, Steven E. and Daxinger, Lucia (2021). The role of MORC3 in silencing transposable elements in mouse embryonic stem cells. Epigenetics and Chromatin, 14 (1) 49, 49. doi: 10.1186/s13072-021-00420-9 |
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2021 Journal Article Radiomics biomarkers correlate with CD8 expression and predict immune signatures in melanoma patientsAoude, Lauren G., Wong, Bernadette, Bonazzi, Vanessa F, Brosda, Sandra, Walters, Shaun B., Koufariotis, Lambros T., Naeini, Marjan M., Pearson, John V, Oey, Harald, Patel, Kalpana, Bradford, Julia J., Bloxham, Conor J, Atkinson, Victoria, Law, Phillip, Strutton, Geoffrey, Bayley, Gerard, Yang, Samuel, Smithers, B. Mark, Waddell, Nicola, Miles, Kenneth and Barbour, Andrew P. (2021). Radiomics biomarkers correlate with CD8 expression and predict immune signatures in melanoma patients. Molecular Cancer Research, 19 (6) molcanres.1038.2020, 950-956. doi: 10.1158/1541-7786.mcr-20-1038 |
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2021 Journal Article EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entityGandhi, Maher K., Hoang, Thanh, Law, Soi C., Brosda, Sandra, O'Rourke, Kacey, Tobin, Joshua W. D., Vari, Frank, Murigneux, Valentine, Fink, J. Lynn, Gunawardana, Jay, Gould, Clare M., Oey, Harald, Bednarska, Karolina, Delecluse, Susanne, Trappe, Ralf Ulrich, de Long, Lilia Merida, Sabdia, Muhammed Bilal, Bhagat, Govind, Hapgood, Greg, Blyth, Emily, Clancy, Leighton E., Wight, Joel, Hawkes, Eliza A., Rimsza, Lisa M., Maguire, Alanna, Bojarczuk, Kamil, Chapuy, Bjoern and Keane, Colm (2021). EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity. Blood, 137 (11), 1468-1477. doi: 10.1182/blood.2020008520 |
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2020 Journal Article Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patientsAoude, Lauren G., Bonazzi, Vanessa F., Brosda, Sandra, Patel, Kalpana, Koufariotis, Lambros T., Oey, Harald, Nones, Katia, Wood, Scott, Pearson, John V., Lonie, James M., Arneil, Melissa, Atkinson, Victoria, Smithers, B. Mark, Waddell, Nicola and Barbour, Andrew P. (2020). Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients. Scientific Reports, 10 (1) 17687, 17687. doi: 10.1038/s41598-020-74956-3 |
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2020 Journal Article Chromosome arm aneuploidies shape tumour evolution and drug responseShukla, Ankit, Nguyen, Thu H. M., Moka, Sarat B., Ellis, Jonathan J., Grady, John P., Oey, Harald, Cristino, Alexandre S., Khanna, Kum Kum, Kroese, Dirk P., Krause, Lutz, Dray, Eloise, Fink, J. Lynn and Duijf, Pascal H. G. (2020). Chromosome arm aneuploidies shape tumour evolution and drug response. Nature Communications, 11 (1) 449, 449. doi: 10.1038/s41467-020-14286-0 |
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2020 Journal Article Targeting an adenosine-mediated “don’t eat me signal” augments anti-lymphoma immunity by anti-CD20 monoclonal antibodyNakamura, Kyohei, Casey, Mika, Oey, Harald, Vari, Frank, Stagg, John, Gandhi, Maher K. and Smyth, Mark J. (2020). Targeting an adenosine-mediated “don’t eat me signal” augments anti-lymphoma immunity by anti-CD20 monoclonal antibody. Leukemia, 34 (10), 2708-2721. doi: 10.1038/s41375-020-0811-3 |
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2019 Journal Article Whole-genome sequencing of human malignant mesothelioma tumours and cell linesOey, Harald, Daniels, Marissa, Relan, Vandana, Chee, Tian Mun, Davidson, Morgan R., Yang, Ian A., Ellis, Jonathan J., Fong, Kwun M., Krause, Lutz and Bowman, Rayleen V. (2019). Whole-genome sequencing of human malignant mesothelioma tumours and cell lines. Carcinogenesis, 40 (6), 724-734. doi: 10.1093/carcin/bgz066 |
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2019 Conference Publication EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapyGandhi, M.K., Hoang, T., Tobin, J.W., Law, S.C., Talaulikar, D., Jain, S., Vari, F., Murigneux, V., Fink, L., Gunawardana, J., Gould, C., Oey, H., Delecluse, S., Trappe, R.U., Merida de Long, L., Sabdia, M.B., Bhagat, G., Hapgood, G., Blyth, E., Clancy, L., Casey, J., Wight, J., Hawkes, E. and Keane, C. (2019). EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy. 15th International Conference on Malignant Lymphoma, Lugano, Switzerland, 18–22 June 2019. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.91_2629 |
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2019 Conference Publication Fusion genes identified from whole genome and whole transcriptome sequencing of malignant pleural mesothelioma tumoursChee, T. M., Oey, H., Fong, K., Yang, I., Krause, L. and Bowman, R. (2019). Fusion genes identified from whole genome and whole transcriptome sequencing of malignant pleural mesothelioma tumours. IASLC 2019 World Conference on Lung Cancer, Barcelona, Spain, 7-10 September 2019. New York, NY, United States: Elsevier . doi: 10.1016/j.jtho.2019.08.697 |
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2019 Journal Article Whole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobiumOey, Harald, Zakrzewski, Martha, Gravermann, Kerstin, Young, Neil D., Korhonen, Pasi K., Gobert, Geoffrey N., Nawaratna, Sujeevi, Hasan, Shihab, Martínez, David M., You, Hong, Lavin, Martin, Jones, Malcolm K., Ragan, Mark A., Stoye, Jens, Oleaga, Ana, Emery, Aidan M., Webster, Bonnie, Rollinson, David, Gasser, Robin B., McManus, Donald P. and Krause, Lutz (2019). Whole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobium. PLOS Pathogens, 15 (1) e1007513, e1007513. doi: 10.1371/journal.ppat.1007513 |
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2019 Conference Publication B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCLGould, Clare, Keane, Colm, Murigneux, Valentine, Oey, Harald, Ellis, Jonathan, Birch, Simone, Gunawardana, Jay, Talaulikar, Dipti, Hertzberg, Mark S., Jones, Kimberley and Gandhi, Maher K. (2019). B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCL. ASH Annual Meeting, Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-126537 |
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2018 Journal Article Whole-genome sequence of the oriental lung fluke Paragonimus westermaniOey, Harald, Zakrzewski, Martha, Narain, Kanwar, Devi, K Rekha, Agatsuma, Takeshi, Nawaratna, Sujeevi, Gobart, Geoffrey, Jones, Malcolm, Ragan, Mark A, McManus, Donald P and Krause, Lutz (2018). Whole-genome sequence of the oriental lung fluke Paragonimus westermani. GigaScience, 8 (1). doi: 10.1093/gigascience/giy146 |
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2016 Journal Article Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinomaKrause, Lutz, Nones, Katia , Loffler, Kelly A., Nancarrow, Derek, Oey, Harald , Tang, Yue Hang, Wayte, Nicola J., Patch, Ann Marie, Patel, Kalpana , Brosda, Sandra, Manning, Suzanne, Lampe, Guy, Clouston, Andrew, Thomas, Janine, Stoye, Jens, Hussey, Damian J., Watson, David I., Lord, Reginald V., Phillips, Wayne A., Gotley, David, Smithers, B. Mark, Whiteman, David C., Hayward, Nicholas K., Grimmond, Sean M., Waddell, Nicola and Barbour, Andrew P. (2016). Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma. Carcinogenesis, 37 (4), 356-365. doi: 10.1093/carcin/bgw018 |
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2016 Journal Article Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouseIsbel, Luke, Prokopuk, Lexie, Wu, Haoyu, Daxinger, Lucia, Oey, Harald, Spurling, Alex, Lawther, Adam J., Hale, Matthew W. and Whitelaw, Emma (2016). Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse. eLife, 5 (JULY) e15082. doi: 10.7554/eLife.15082 |
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2016 Journal Article Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotypeDaxinger, Lucia, Oey, Harald, Isbel, Luke, Whitelaw, Nadia C., Youngson, Neil A., Spurling, Alex, Vonk, Kelly K. D. and Whitelaw, Emma (2016). Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype. Scientific Reports, 6 (1) 25004, e25004.1-e25004.10. doi: 10.1038/srep25004 |
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2015 Journal Article Genetic and epigenetic variation among inbred mouse littermates: Identification of inter-individual differentially methylated regionsOey, Harald, Isbel, Luke, Hickey, Peter, Ebaid, Basant and Whitelaw, Emma (2015). Genetic and epigenetic variation among inbred mouse littermates: Identification of inter-individual differentially methylated regions. Epigenetics and Chromatin, 8 (54) 47, 54. doi: 10.1186/s13072-015-0047-z |
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2015 Journal Article The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancersHarten, Sarah K., Oey, Harald, Bourke, Lauren M., Bharti, Vandhana, Isbel, Luke, Daxinger, Lucia, Faou, Pierre, Robertson, Neil, Matthews, Jacqueline M. and Whitelaw, Emma (2015). The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers. BMC Biology, 13 (21) 21, 1-15. doi: 10.1186/s12915-015-0128-2 |
