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2016

Journal Article

The snake with the scorpion's sting: novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus)

Yang, Daryl C., Deuis, Jennifer R., Dashevsky, Daniel, Dobson, James, Jackson, Timothy N. W., Brust, Andreas, Xie, Bing, Koludarov, Ivan, Debono, Jordan, Hendrikx, Iwan, Hodgson, Wayne C., Josh, Peter, Nouwens, Amanda, Baillie, Gregory J., Bruxner, Timothy J. C., Alewood, Paul F., Peng Lim, Kelvin Kok, Frank, Nathaniel, Vetter, Irina and Fry, Bryan G. (2016). The snake with the scorpion's sting: novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus). Toxins, 8 (10) A034, 303. doi: 10.3390/toxins8100303

The snake with the scorpion's sting: novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus)

2016

Journal Article

Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target

Yin, Kathleen, Deuis, Jennifer R., Lewis, Richard J. and Vetter, Irina (2016). Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target. Molecular Pain, 12, 1-13. doi: 10.1177/1744806916665366

Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target

2016

Journal Article

Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8

Deuis, Jennifer R, Dekan, Zoltan, Inserra, Marco C., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Craik, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Schroeder, Christina I., Henriques, Sónia Troeira and Vetter, Irina (2016). Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8. Journal of Biological Chemistry, 291 (22), 11829-11842. doi: 10.1074/jbc.M116.721662

Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8

2016

Journal Article

Analgesic effects of GpTx-1, PF-04856264 and CNV1014802 in a mouse model of NaV1.7-Mediated pain

Deuis, Jennifer R., Wingerd, Joshua S., Winter, Zoltan, Durek, Thomas, Dekan, Zoltan, Sousa, Silmara R., Zimmermann, Katharina, Hoffmann, Tali, Weidner, Christian, Nassar, Mohammed A., Alewood, Paul F., Lewis, Richard J. and Vetter, Irina (2016). Analgesic effects of GpTx-1, PF-04856264 and CNV1014802 in a mouse model of NaV1.7-Mediated pain. Toxins, 8 (3) 78, 78. doi: 10.3390/toxins8030078

Analgesic effects of GpTx-1, PF-04856264 and CNV1014802 in a mouse model of NaV1.7-Mediated pain

2016

Journal Article

The thermal probe test: a novel behavioral assay to quantify thermal paw withdrawal thresholds in mice

Deuis, Jennifer R. and Vetter, Irina (2016). The thermal probe test: a novel behavioral assay to quantify thermal paw withdrawal thresholds in mice. Temperature, 3 (2), 199-207. doi: 10.1080/23328940.2016.1157668

The thermal probe test: a novel behavioral assay to quantify thermal paw withdrawal thresholds in mice

2015

Journal Article

Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesia

Deuis, Jennifer, Whately, Ella, Brust, Andreas, Inserra, Marco, Asvadi, Naghmeh Hajarol, Lewis, Richard J., Alewood, Paul F., Cabot, Peter J. and Vetter, Irina (2015). Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesia. ACS Chemical Neuroscience, 6 (10), 1751-1758. doi: 10.1021/acschemneuro.5b00113

Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesia

2015

Journal Article

Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens

Cardoso, Fernanda C., Deka, Zoltan, Rosengren, K. Johan, Erickson, Andelain, Vetter, Irina, Deuis, Jennifer R., Herzig, Volker, Alewood, Paul F., King, Glenn F. and Lewis, Richard J. (2015). Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens. Molecular Pharmacology, 88 (2), 291-303. doi: 10.1124/mol.115.098178

Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens

2015

Journal Article

α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors

Mueller, Alexander, Starobova, Hana, Inserra, Marco C., Jin, Ai-Hua, Deuis, Jennifer R., Dutertre, Sebastien, Lewis, Richard J., Alewood, Paul F., Daly, Norelle L. and Vetter, Irina (2015). α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology, 94 (2), 155-163. doi: 10.1016/j.bcp.2015.01.011

α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors

2014

Journal Article

Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin

Deuis, Jennifer R., Lim, Yu Ling, Rodrigues de Sousa, Silmara, Lewis, Richard J., Alewood, Paul F., Cabot, Peter J. and Vetter, Irina (2014). Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin. Neuro-Oncology, 16 (10), 1324-1332. doi: 10.1093/neuonc/nou048

Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin

2013

Journal Article

Analgesic treatment of ciguatoxin-induced cold allodynia

Zimmermann, Katharina, Deuis, Jennifer R., Inserra, Marco C., Collins, Lindon S., Namer, Barbara, Cabot, Peter J., Reeh, Peter W., Lewis, Richard J. and Vetter, Irina (2013). Analgesic treatment of ciguatoxin-induced cold allodynia. Pain, 154 (10), 1999-2006. doi: 10.1016/j.pain.2013.06.015

Analgesic treatment of ciguatoxin-induced cold allodynia

2013

Journal Article

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na(v)1.6 in peripheral pain pathways

Deuis, Jennifer R., Zimmermann, Katharina, Romanovsky, Andrej A., Possani, Lourival D., Cabot, Peter J., Lewis, Richard J. and Vetter, Irina (2013). An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na(v)1.6 in peripheral pain pathways. Pain, 154 (9), 1749-1757. doi: 10.1016/j.pain.2013.05.032

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na(v)1.6 in peripheral pain pathways