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2021

Other Outputs

Improving GWAS discovery and genomic prediction accuracy in Biobank data

Orliac, Etienne J., Banos, Daniel Trejo, Ojavee, Sven E., Läll, Kristi, Mägi, Reedik, Visscher, Peter M. and Robinson, Matthew R. (2021). Improving GWAS discovery and genomic prediction accuracy in Biobank data. doi: 10.1101/2021.08.12.456099

Improving GWAS discovery and genomic prediction accuracy in Biobank data

2020

Other Outputs

Epigenetic scores for the circulating proteome as tools for disease prediction

Gadd, Danni A, Hillary, Robert F, McCartney, Daniel L, Zaghlool, Shaza B, Stevenson, Anna J, Nangle, Cliff, Campbell, Archie, Flaig, Robin, Harris, Sarah E, Walker, Rosie M, Shi, Liu, Tucker-Drob, Elliot M, Gieger, Christian, Peters, Annette, Waldenberger, Melanie, Graumann, Johannes, McRae, Allan F, Deary, Ian J, Porteous, David J, Hayward, Caroline, Visscher, Peter M, Cox, Simon R, Evans, Kathryn L, McIntosh, Andrew M, Suhre, Karsten and Marioni, Riccardo E (2020). Epigenetic scores for the circulating proteome as tools for disease prediction. doi: 10.1101/2020.12.01.404681

Epigenetic scores for the circulating proteome as tools for disease prediction

2020

Other Outputs

A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts

Ni, Guiyan, Zeng, Jian, Revez, Joana A, Wang, Ying, Zheng, Zhili, Ge, Tian, Restuadi, Restuadi, Kiewa, Jacqueline, Nyholt, Dale R, Coleman, Jonathan R I, Smoller, Jordan W, Consortium, Schizophrenia Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Yang, Jian, Visscher, Peter M and Wray, Naomi R (2020). A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts. doi: 10.1101/2020.09.10.20192310

A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts

2020

Other Outputs

Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes

Xue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2020). Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes. doi: 10.1101/2020.06.15.20131284

Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes

2020

Other Outputs

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

Wang, Ying, Guo, Jing, Ni, Guiyan, Yang, Jian, Visscher, Peter M. and Yengo, Loic (2020). Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations. doi: 10.1101/2020.01.14.905927

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

2019

Other Outputs

Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco Consumption

Palmer, Rohan H C, Benca-Bachman, Chelsie E., Bubier, Jason A., McGeary, John E, Ramgiri, Nikhil, Srijeyanthan, Jenani, Huggett, Spencer, Yang, Jingjing, Visscher, Peter, Yang, Jian, Knopik, Valerie and Chesler, Elissa J. (2019). Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco Consumption. doi: 10.1101/2019.12.23.887083

Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco Consumption

2019

Other Outputs

No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)

Yengo, Loic, Sidari, Morgan, Verweij, Karin J. H., Visscher, Peter M., Keller, Matthew C. and Zietsch, Brendan P. (2019). No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018). doi: 10.1101/643304

No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)

2019

Other Outputs

An epigenome-wide association study of sex-specific chronological ageing

McCartney, Daniel L., Hillary, Robert F., Zhang, Qian, Stevenson, Anna J., Walker, Rosie M., Bermingham, Mairead L., Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., Evans, Kathryn L., Chandra, Tamir, Deary, Ian J., McIntosh, Andrew M., Visscher, Peter M., McRae, Allan F. and Marioni, Riccardo E. (2019). An epigenome-wide association study of sex-specific chronological ageing. doi: 10.1101/606020

An epigenome-wide association study of sex-specific chronological ageing

2019

Other Outputs

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

Byrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Consortium, Bipolar Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian and Wray, Naomi R (2019). Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders. doi: 10.1101/592899

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

2019

Other Outputs

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936. doi: 10.1101/558940

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

2019

Other Outputs

Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tonu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. doi: 10.1101/522961

Improved polygenic prediction by Bayesian multiple regression on summary statistics

2018

Other Outputs

Genetic analyses of medication-use and implications for precision medicine

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2018). Genetic analyses of medication-use and implications for precision medicine. doi: 10.1101/501049

Genetic analyses of medication-use and implications for precision medicine

2018

Other Outputs

Epigenetic signatures of starting and stopping smoking

McCartney, Daniel L, Stevenson, Anna J, Hillary, Robert F, Walker, Rosie M, Bermingham, Mairead L, Morris, Stewart W, Clarke, Toni-Kim, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Porteous, David J, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J and Marioni, Riccardo E (2018). Epigenetic signatures of starting and stopping smoking. doi: 10.1101/402453

Epigenetic signatures of starting and stopping smoking

2018

Other Outputs

Epigenetic prediction of complex traits and death

McCartney, Daniel L, Stevenson, Anna J, Ritchie, Stuart J, Walker, Rosie M, Zhang, Qian, Morris, Stewart W, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Gale, Catharine R, Porteous, David J, Haley, Chris S, McRae, Allan F, Wray, Naomi R, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J and Marioni, Riccardo E (2018). Epigenetic prediction of complex traits and death. doi: 10.1101/294116

Epigenetic prediction of complex traits and death

2018

Other Outputs

GWAS on family history of Alzheimer’s disease

Marioni, Riccardo E., Harris, Sarah E., McRae, Allan F., Zhang, Qian, Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine, Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer’s disease. doi: 10.1101/246223

GWAS on family history of Alzheimer’s disease

2017

Other Outputs

Causal associations between risk factors and common diseases inferred from GWAS summary data

Zhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J., Visscher, Peter M., Wray, Naomi R. and Yang, Jian (2017). Causal associations between risk factors and common diseases inferred from GWAS summary data. doi: 10.1101/168674

Causal associations between risk factors and common diseases inferred from GWAS summary data

2017

Other Outputs

Widespread signatures of negative selection in the genetic architecture of human complex traits

Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R, Lloyd-Jones, Luke, Yengo, Loic, Yap, Chloe, Xue, Angli, Sidorenko, Julia, McRae, Allan F, Powell, Joseph E, Montgomery, Grant W, Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R, Visscher, Peter M and Yang, Jian (2017). Widespread signatures of negative selection in the genetic architecture of human complex traits. doi: 10.1101/145755

Widespread signatures of negative selection in the genetic architecture of human complex traits