2021 Other Outputs Improving GWAS discovery and genomic prediction accuracy in Biobank dataOrliac, Etienne J., Banos, Daniel Trejo, Ojavee, Sven E., Läll, Kristi, Mägi, Reedik, Visscher, Peter M. and Robinson, Matthew R. (2021). Improving GWAS discovery and genomic prediction accuracy in Biobank data. doi: 10.1101/2021.08.12.456099 |
2020 Other Outputs Epigenetic scores for the circulating proteome as tools for disease predictionGadd, Danni A, Hillary, Robert F, McCartney, Daniel L, Zaghlool, Shaza B, Stevenson, Anna J, Nangle, Cliff, Campbell, Archie, Flaig, Robin, Harris, Sarah E, Walker, Rosie M, Shi, Liu, Tucker-Drob, Elliot M, Gieger, Christian, Peters, Annette, Waldenberger, Melanie, Graumann, Johannes, McRae, Allan F, Deary, Ian J, Porteous, David J, Hayward, Caroline, Visscher, Peter M, Cox, Simon R, Evans, Kathryn L, McIntosh, Andrew M, Suhre, Karsten and Marioni, Riccardo E (2020). Epigenetic scores for the circulating proteome as tools for disease prediction. doi: 10.1101/2020.12.01.404681 |
2020 Other Outputs A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohortsNi, Guiyan, Zeng, Jian, Revez, Joana A, Wang, Ying, Zheng, Zhili, Ge, Tian, Restuadi, Restuadi, Kiewa, Jacqueline, Nyholt, Dale R, Coleman, Jonathan R I, Smoller, Jordan W, Consortium, Schizophrenia Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Yang, Jian, Visscher, Peter M and Wray, Naomi R (2020). A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts. doi: 10.1101/2020.09.10.20192310 |
2020 Other Outputs Genome-wide analyses of behavioural traits biased by misreports and longitudinal changesXue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2020). Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes. doi: 10.1101/2020.06.15.20131284 |
2020 Other Outputs Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populationsWang, Ying, Guo, Jing, Ni, Guiyan, Yang, Jian, Visscher, Peter M. and Yengo, Loic (2020). Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations. doi: 10.1101/2020.01.14.905927 |
2019 Other Outputs Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco ConsumptionPalmer, Rohan H C, Benca-Bachman, Chelsie E., Bubier, Jason A., McGeary, John E, Ramgiri, Nikhil, Srijeyanthan, Jenani, Huggett, Spencer, Yang, Jingjing, Visscher, Peter, Yang, Jian, Knopik, Valerie and Chesler, Elissa J. (2019). Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco Consumption. doi: 10.1101/2019.12.23.887083 |
2019 Other Outputs No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)Yengo, Loic, Sidari, Morgan, Verweij, Karin J. H., Visscher, Peter M., Keller, Matthew C. and Zietsch, Brendan P. (2019). No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018). doi: 10.1101/643304 |
2019 Other Outputs An epigenome-wide association study of sex-specific chronological ageingMcCartney, Daniel L., Hillary, Robert F., Zhang, Qian, Stevenson, Anna J., Walker, Rosie M., Bermingham, Mairead L., Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., Evans, Kathryn L., Chandra, Tamir, Deary, Ian J., McIntosh, Andrew M., Visscher, Peter M., McRae, Allan F. and Marioni, Riccardo E. (2019). An epigenome-wide association study of sex-specific chronological ageing. doi: 10.1101/606020 |
2019 Other Outputs Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disordersByrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Consortium, Bipolar Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian and Wray, Naomi R (2019). Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders. doi: 10.1101/592899 |
2019 Other Outputs Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936. doi: 10.1101/558940 |
2019 Other Outputs Improved polygenic prediction by Bayesian multiple regression on summary statisticsLloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tonu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. doi: 10.1101/522961 |
2018 Other Outputs Genetic analyses of medication-use and implications for precision medicineWu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2018). Genetic analyses of medication-use and implications for precision medicine. doi: 10.1101/501049 |
2018 Other Outputs Epigenetic signatures of starting and stopping smokingMcCartney, Daniel L, Stevenson, Anna J, Hillary, Robert F, Walker, Rosie M, Bermingham, Mairead L, Morris, Stewart W, Clarke, Toni-Kim, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Porteous, David J, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J and Marioni, Riccardo E (2018). Epigenetic signatures of starting and stopping smoking. doi: 10.1101/402453 |
2018 Other Outputs Epigenetic prediction of complex traits and deathMcCartney, Daniel L, Stevenson, Anna J, Ritchie, Stuart J, Walker, Rosie M, Zhang, Qian, Morris, Stewart W, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Gale, Catharine R, Porteous, David J, Haley, Chris S, McRae, Allan F, Wray, Naomi R, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J and Marioni, Riccardo E (2018). Epigenetic prediction of complex traits and death. doi: 10.1101/294116 |
2018 Other Outputs GWAS on family history of Alzheimer’s diseaseMarioni, Riccardo E., Harris, Sarah E., McRae, Allan F., Zhang, Qian, Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine, Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer’s disease. doi: 10.1101/246223 |
2017 Other Outputs Causal associations between risk factors and common diseases inferred from GWAS summary dataZhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J., Visscher, Peter M., Wray, Naomi R. and Yang, Jian (2017). Causal associations between risk factors and common diseases inferred from GWAS summary data. doi: 10.1101/168674 |
2017 Other Outputs Widespread signatures of negative selection in the genetic architecture of human complex traitsZeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R, Lloyd-Jones, Luke, Yengo, Loic, Yap, Chloe, Xue, Angli, Sidorenko, Julia, McRae, Allan F, Powell, Joseph E, Montgomery, Grant W, Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R, Visscher, Peter M and Yang, Jian (2017). Widespread signatures of negative selection in the genetic architecture of human complex traits. doi: 10.1101/145755 |