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2009 Journal Article hnRNP-U is a specific DNA-dependent protein kinase substrate phosphorylated in response to DNA double-strand breaksBerglund, Fredfk M. and Clarke, Paul R. (2009). hnRNP-U is a specific DNA-dependent protein kinase substrate phosphorylated in response to DNA double-strand breaks. Biochemical and Biophysical Research Communications, 381 (1), 59-64. doi: 10.1016/j.bbrc.2009.02.019 |
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2008 Journal Article DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmineSeifert, Anne, Allan, Lindsey A. and Clarke, Paul R. (2008). DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine. Febs Journal, 275 (24), 6268-6280. doi: 10.1111/j.1742-4658.2008.06751.x |
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2008 Journal Article Spatial and temporal coordination of mitosis by Ran GTPaseClarke, Paul R. and Zhang, Chuanmao (2008). Spatial and temporal coordination of mitosis by Ran GTPase. Nature Reviews Molecular Cell Biology, 9 (6), 464-477. doi: 10.1038/nrm2410 |
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2008 Journal Article Claspin is phosphorylated in the Chk1-binding domain by a kinase distinct from Chk1Bennett, Lara N., Larkin, Conor, Gillespie, David A. and Clarke, Paul R. (2008). Claspin is phosphorylated in the Chk1-binding domain by a kinase distinct from Chk1. Biochemical and Biophysical Research Communications, 369 (3), 973-976. doi: 10.1016/j.bbrc.2008.02.154 |
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2008 Journal Article Signaling to nuclear transport.Clarke, Paul R. (2008). Signaling to nuclear transport.. Developmental Cell, 14 (3), 316-318. doi: 10.1016/j.devcel.2008.02.005 |
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2008 Journal Article The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125Martin, Morag C., Allan, Lindsey A., Mancini, Erika J. and Clarke, Paul R. (2008). The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125. Journal of Biological Chemistry, 283 (7), 3854-3865. doi: 10.1074/jbc.M705647200 |
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2008 Journal Article Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosisChen, Qiang, Zhang, Xiaoyan, Jiang, Qing, Clarke, Paul R. and Zhang, Chuamnao (2008). Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis. Cell Research, 18 (2), 268-280. doi: 10.1038/cr.2008.11 |
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2008 Journal Article A mechanism coupling cell division and the control of apoptosisAllan, Lindsey A and Clarke, Paul R (2008). A mechanism coupling cell division and the control of apoptosis. SEB experimental biology series, 59, 257-265. |
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2007 Journal Article RCC1 isoforms differ in their affinity for chromatin, molecular interactions and regulation by phosphorylationHood, Fiona E. and Clarke, Paul R. (2007). RCC1 isoforms differ in their affinity for chromatin, molecular interactions and regulation by phosphorylation. Journal of Cell Science, 120 (19), 3436-3445. doi: 10.1242/jcs.009092 |
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2007 Journal Article Mitosis: Ran scales the alps of spindle formationClarke, Paul R. and Sazer, Shelley (2007). Mitosis: Ran scales the alps of spindle formation. Current Biology, 17 (16), R643-R645. doi: 10.1016/j.cub.2007.06.023 |
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2007 Journal Article Anchoring RCC1 by the tailClarke, Paul R. (2007). Anchoring RCC1 by the tail. Nature Cell Biology, 9 (5), 485-487. doi: 10.1038/ncb0507-485 |
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2007 Journal Article Phosphorylation of Caspase-9 by CDK1/Cyclin B1 Protects Mitotic Cells against ApoptosisAllan, Lindsey A. and Clarke, Paul R. (2007). Phosphorylation of Caspase-9 by CDK1/Cyclin B1 Protects Mitotic Cells against Apoptosis. Molecular Cell, 26 (2), 301-310. doi: 10.1016/j.molcel.2007.03.019 |
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2006 Journal Article A mitotic role for BRCA1/BARD1 in tumor suppression?Clarke, Paul R. and Sanderson, Helen S. (2006). A mitotic role for BRCA1/BARD1 in tumor suppression?. Cell, 127 (3), 453-455. doi: 10.1016/j.cell.2006.10.020 |
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2006 Journal Article Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activationBennett, Lara N. and Clarke, Paul R. (2006). Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activation. Febs Letters, 580 (17), 4176-4181. doi: 10.1016/j.febslet.2006.06.071 |
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2006 Journal Article Cell biology: Ran, mitosis and the cancer LconnectionSanderson, HS and Clarke, PR (2006). Cell biology: Ran, mitosis and the cancer Lconnection. Current Biology, 16 (12), R466-R468. doi: 10.1016/j.cub.2006.05.032 |
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2005 Journal Article Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stressBrady, S. C., Allan, L. A. and Clarke, P. R. (2005). Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stress. Molecular and Cellular Biology, 25 (23), 10543-10555. doi: 10.1128/MCB.25.23.10543-10555.2005 |
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2005 Journal Article Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathwayClarke, Catriona A. L., Bennett, Lara N. and Clarke, Paul R. (2005). Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway. Journal of Biological Chemistry, 280 (42), 35337-35345. doi: 10.1074/jbc.M506460200 |
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2005 Journal Article A gradient signal orchestrates the mitotic spindleClarke, PR (2005). A gradient signal orchestrates the mitotic spindle. Science, 309 (5739), 1334-1335. doi: 10.1126/science.1117842 |
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2005 Journal Article DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free systemClarke, CAL and Clarke, PR (2005). DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. Biochemical Journal, 388 (2), 705-712. doi: 10.1042/BJ20041966 |
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2005 Journal Article The Crm de la crème of mitosisClarke, PR (2005). The Crm de la crème of mitosis. Nature Cell Biology, 7 (6), 551-552. doi: 10.1038/ncb0605-551 |
