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2005

Journal Article

Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c

Martin, MC, Allan, LA, Lickrish, M, Sampson, C, Morrice, N and Clarke, PR (2005). Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. Journal of Biological Chemistry, 280 (15), 15449-15455. doi: 10.1074/jbc.M414325200

Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c

2005

Journal Article

Regulation of Cdc2/cyclin B activation in xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca2+/calmodulin-dependent protein kinase II. (vol 14, pg 4003, 2003)

Hutchins, JRA, Dikovskaya, D and Clarke, PR (2005). Regulation of Cdc2/cyclin B activation in xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca2+/calmodulin-dependent protein kinase II. (vol 14, pg 4003, 2003). Molecular Biology of the Cell, 16 (3), 1568-1568.

Regulation of Cdc2/cyclin B activation in xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca2+/calmodulin-dependent protein kinase II. (vol 14, pg 4003, 2003)

2004

Journal Article

Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis

Hutchins, JRA, Moore, WJ, Hood, FE, Wilson, JSJ, Andrews, PD, Swedlow, JR and Clarke, PR (2004). Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis. Current Biology, 14 (12), 1099-1104. doi: 10.1016/j.cub.2004.05.021

Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis

2004

Journal Article

Spatial and temporal control of nuclear envelope assembly by Ran GTPase

Clarke, Paul R and Zhang, Chuanmao (2004). Spatial and temporal control of nuclear envelope assembly by Ran GTPase. Symposia of the Society for Experimental Biology (56), 193-204.

Spatial and temporal control of nuclear envelope assembly by Ran GTPase

2004

Journal Article

Many fingers on the mitotic trigger - Post-translational regulation of the Cdc25C phosphatase

Hutchins, JRA and Clarke, PR (2004). Many fingers on the mitotic trigger - Post-translational regulation of the Cdc25C phosphatase. Cell Cycle, 3 (1), 41-45.

Many fingers on the mitotic trigger - Post-translational regulation of the Cdc25C phosphatase

2003

Journal Article

Nuclear pores: Sowing the seeds of assembly on the chromatin landscape

Wozniak, R and Clarke, PR (2003). Nuclear pores: Sowing the seeds of assembly on the chromatin landscape. Current Biology, 13 (24), R970-R972. doi: 10.1016/j.cub.2003.11.046

Nuclear pores: Sowing the seeds of assembly on the chromatin landscape

2003

Journal Article

Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25c phosphatase by Ca 2+/calmodium-dependent kinase II

Hutchins, James R. A., Dikovskaya, D. and Clarke, P. R. (2003). Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25c phosphatase by Ca 2+/calmodium-dependent kinase II. Molecular Biology of the Cell, 14 (10), 4003-4014. doi: 10.1091/mbc.E03-02-0061

Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25c phosphatase by Ca 2+/calmodium-dependent kinase II

2003

Journal Article

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK

Allan, LA, Morrice, N, Brady, S, Magee, G, Pathak, S and Clarke, PR (2003). Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. Nature Cell Biology, 5 (7), 647-654. doi: 10.1038/ncb1005

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK

2002

Journal Article

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly

Zhang, Chuanmao, Goldberg, Martin W., Moore, William J., Allen, Terence D. and Clarke, Paul R. (2002). Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly. European Journal of Cell Biology, 81 (11), 623-633. doi: 10.1078/0171-9335-00288

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly

2002

Journal Article

Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding

Hutchins, JRA, Dikovskaya, D and Clarke, PR (2002). Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding. Febs Letters, 528 (1-3), 267-271. doi: 10.1016/S0014-5793(02)03327-6

Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding

2002

Journal Article

Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells

Moore, WJ, Zhang, CM and Clarke, PR (2002). Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. Current Biology, 12 (16), 1442-1447. doi: 10.1016/S0960-9822(02)01076-X

Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells

2002

Journal Article

The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope

Timinszky, G, Tirian, L, Nagy, FT, Toth, G, Perczel, A, Kiss-Laszlo, Z, Boros, I, Clarke, PR and Szabad, J (2002). The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope. Journal of Cell Science, 115 (8), 1675-1687.

The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope

2002

Journal Article

Role of importin-β in the control of nuclear envelope assembly by Ran

Zhang, CM, Hutchins, JRA, Muhlhausser, P, Kutay, U and Clarke, PR (2002). Role of importin-β in the control of nuclear envelope assembly by Ran. Current Biology, 12 (6), 498-502. doi: 10.1016/S0960-9822(02)00714-5

Role of importin-β in the control of nuclear envelope assembly by Ran

2001

Journal Article

Ran GTPase: A master regulator of nuclear structure and function during the eukaryotic cell division cycle?

Clarke, PR and Zhang, CM (2001). Ran GTPase: A master regulator of nuclear structure and function during the eukaryotic cell division cycle?. Trends in Cell Biology, 11 (9), 366-371. doi: 10.1016/S0962-8924(01)02071-2

Ran GTPase: A master regulator of nuclear structure and function during the eukaryotic cell division cycle?

2001

Journal Article

XMog1, a nuclear Ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe Mog1p that co-operates with RanBP1 to control generation of Ran-GTP

Nicolas, FJ, Moore, WJ, Zhang, CM and Clarke, PR (2001). XMog1, a nuclear Ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe Mog1p that co-operates with RanBP1 to control generation of Ran-GTP. Journal of Cell Science, 114 (16), 3013-3023.

XMog1, a nuclear Ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe Mog1p that co-operates with RanBP1 to control generation of Ran-GTP

2001

Journal Article

Inhibition of the G2 DNA Damage Checkpoint and of Protein Kinases Chk1 and Chk2 by the Marine Sponge Alkaloid Debromohymenialdisine

Curman, D, Cinel, B, Williams, DE, Rundle, N, Block, WD, Goodarzi, AA, Hutchins, JR, Clarke, PR, Zhou, BB, Lees-Miller, SP, Andersen, RJ and Roberge, M (2001). Inhibition of the G2 DNA Damage Checkpoint and of Protein Kinases Chk1 and Chk2 by the Marine Sponge Alkaloid Debromohymenialdisine. Journal of Biological Chemistry, 276 (21), 17914-17919. doi: 10.1074/jbc.M100728200

Inhibition of the G2 DNA Damage Checkpoint and of Protein Kinases Chk1 and Chk2 by the Marine Sponge Alkaloid Debromohymenialdisine

2001

Journal Article

Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system

Zhang, CM and Clarke, PR (2001). Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system. Current Biology, 11 (3), 208-212. doi: 10.1016/S0960-9822(01)00053-7

Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system

2000

Journal Article

Ran alters nuclear pore complex conformation

Goldberg, MW, Rutherford, SA, Hughes, M, Cotter, LA, Bagley, S, Kiseleva, E, Allen, TD and Clarke, PR (2000). Ran alters nuclear pore complex conformation. Journal of Molecular Biology, 300 (3), 519-529. doi: 10.1006/jmbi.2000.3891

Ran alters nuclear pore complex conformation

2000

Journal Article

Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts

Zhang, CM and Clarke, PR (2000). Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts. Science, 288 (5470), 1429-1432. doi: 10.1126/science.288.5470.1429

Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts

2000

Journal Article

Substrate specificity determinants of the checkpoint protein kinase Chk1

Hutchins, JRA, Hughes, M and Clarke, PR (2000). Substrate specificity determinants of the checkpoint protein kinase Chk1. Febs Letters, 466 (1), 91-95. doi: 10.1016/S0014-5793(99)01763-9

Substrate specificity determinants of the checkpoint protein kinase Chk1