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2020

Conference Publication

Canine PET/CT imaging with 64Cu-nanomedicines

Daniel, Sarah, Houston, Zachary, Fletcher, Nicholas, Bell, Craig, Atcheson, Nicole, Al-Najjar, Aiman, Howard, Christopher, Mahler, Stephen, Straw, Rod and Thurecht, Kristofer (2020). Canine PET/CT imaging with 64Cu-nanomedicines. SNMMI Annual Meeting, Online, 11-14 July, 2020. Reston, VA, United States: Society of Nuclear Medicine.

Canine PET/CT imaging with 64Cu-nanomedicines

2020

Journal Article

Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies

Houston, Zachary H., Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B., Fletcher, Nicholas L., Fuchs, Adrian V., Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W., Mahler, Stephen M., Richards, Linda J., Caruso, Frank and Thurecht, Kristofer J. (2020). Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies. ACS Central Science, 6 (5) acscentsci.9b01299, 727-738. doi: 10.1021/acscentsci.9b01299

Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies

2020

Journal Article

Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study

Playford, Elliott Geoffrey, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2020). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study. The Lancet Infectious Diseases, 20 (4), 445-454. doi: 10.1016/S1473-3099(19)30634-6

Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study

2020

Journal Article

Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production

Henry, Matthew N., MacDonald, Michael A., Orellana, Camila A., Gray, Peter P., Gillard, Marianne, Baker, Kym, Nielsen, Lars K., Marcellin, Esteban, Mahler, Stephen and Martinez, Veronica S. (2020). Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production. Biotechnology and Bioengineering, 117 (4) bit.27269, 1187-1203. doi: 10.1002/bit.27269

Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production

2020

Journal Article

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

2019

Journal Article

Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing

Raftery, Lyndon J., Howard, Christopher B., Grewal, Yadveer S., Vaidyanathan, Ramanathan, Jones, Martina L., Anderson, Will, Korbie, Darren, Duarte, Tania, Duc Cao, Minh, Nguyen, Son Hoang, Coin, Lachlan JM, Mahler, Stephen M and Trau, Matt (2019). Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing. Lab on a Chip, 19 (24), 4083-4092. doi: 10.1039/c9lc00978g

Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing

2019

Journal Article

Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy

Tang, Jie, Li, Bei, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Wu, Yilun, Huang, Leaf and Xu, Zhi Ping (2019). Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials, 216 119232, 119232. doi: 10.1016/j.biomaterials.2019.119232

Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy

2019

Journal Article

Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments

Islam, Jiaul, Riley, Blake T., Fercher, Christian, Jones, Martina L., Buckle, Ashley M., Howard, Christopher B., Cox, Rosalind P., Bell, Toby D. M., Mahler, Stephen and Corrie, Simon R. (2019). Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments. Analytical Chemistry, 91 (12), 7631-7638. doi: 10.1021/acs.analchem.9b00445

Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments

2019

Journal Article

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

2019

Journal Article

Innovative therapeutic strategies for effective treatment of brain metastases

Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 (6) 1280, 1280. doi: 10.3390/ijms20061280

Innovative therapeutic strategies for effective treatment of brain metastases

2019

Journal Article

Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning

Alfaleh, Mohamed, Arora, Neetika, Yeh, Michael, de Bakker, Christopher, Howard, Christopher, Macpherson, Philip, Allavena, Rachel, Chen, Xiaoli, Harkness, Linda, Mahler, Stephen and Jones, Martina (2019). Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning. Antibodies, 8 (1) 15, 15. doi: 10.3390/antib8010015

Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning

2019

Conference Publication

Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines

Saunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. San Antonio Breast Cancer Symposium, San Antonio, Texas, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P1-19-02

Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines

2019

Book Chapter

Disease-modifying anti-rheumatic drugs

Pile, Kevin D., Graham, Garry G., Mahler, Stephen M. and Day, Richard O. (2019). Disease-modifying anti-rheumatic drugs. Nijkamp and Parnham’s principles of immunopharmacology. (pp. 709-750) edited by Michael J. Parnham, Frans P. Nijkamp and Adriano G. Rossi. Cham, Switzerland: Springer. doi: 10.1007/978-3-030-10811-3_34

Disease-modifying anti-rheumatic drugs

2019

Conference Publication

Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group system

Ekman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina and Bui, Xuan (2019). Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group system. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.353

Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group system

2019

Conference Publication

In silico modelling of glycophorin MNS system blood group antigens

Flower, R., Ekman, S., Mahler, S., Jones, M., Malde, A. K. and Bui, X. (2019). In silico modelling of glycophorin MNS system blood group antigens. In: ANZSBT, Perth, Australia, (24-25). 20-23 October 2019.

In silico modelling of glycophorin MNS system blood group antigens

2019

Conference Publication

In silico model for glycophorin a (GPA) structure

Ekman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina, Treutlein, Herbert and Bui, Xuan (2019). In silico model for glycophorin a (GPA) structure. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.352

In silico model for glycophorin a (GPA) structure

2018

Journal Article

Multiplexed SERS detection of soluble cancer protein biomarkers with gold-silver alloy nanoboxes and nanoyeast single-chain variable fragments

Li, Junrong, Wang, Jing, Grewal, Yadveer S, Howard, Christopher B, Raftery, Lyndon J, Mahler, Stephen, Wang, Yuling and Trau, Matt (2018). Multiplexed SERS detection of soluble cancer protein biomarkers with gold-silver alloy nanoboxes and nanoyeast single-chain variable fragments. Analytical Chemistry, 90 (17) acs.analchem.8b02216, 10377-10384. doi: 10.1021/acs.analchem.8b02216

Multiplexed SERS detection of soluble cancer protein biomarkers with gold-silver alloy nanoboxes and nanoyeast single-chain variable fragments

2018

Journal Article

Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach

Fontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288

Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach

2018

Journal Article

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

Tang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

2018

Journal Article

Recent advances in the generation of antibody-nanomaterial conjugates

Sivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607

Recent advances in the generation of antibody-nanomaterial conjugates