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2017 Journal Article Pancreatic alpha- and beta-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expressionPetrenko, Volodymyr, Saini, Camille, Giovannoni, Laurianne, Gobet, Cedric, Sage, Daniel, Unser, Michael, Masson, Mounia Heddad, Gu, Guoqiang, Bosco, Domenico, Gachon, Frederic, Philippe, Jacques and Dibner, Charna (2017). Pancreatic alpha- and beta-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression. Genes and Development, 31 (4), 383-398. doi: 10.1101/gad.290379.116 |
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2017 Journal Article Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liverWang, Jingkui, Mauvoisin, Daniel, Martin, Eva, Atger, Florian, Galindo, Antonio Nunez, Dayon, Loic, Sizzano, Federico, Palini, Alessio, Kussmann, Martin, Waridel, Patrice, Quadroni, Manfredo, Dulic, Vjekoslav, Naef, Felix and Gachon, Frederic (2017). Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liver. Cell Metabolism, 25 (1), 102-117. doi: 10.1016/j.cmet.2016.10.003 |
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2016 Journal Article Extensive regulation of diurnal transcription and metabolism by glucocorticoidsWeger, Benjamin D., Weger, Meltem, Goerling, Benjamin, Schink, Andrea, Gobet, Cedric, Keime, Celine, Poschet, Gernot, Jost, Bernard, Krone, Nils, Hell, Ruediger, Gachon, Frederic, Luy, Burkhard and Dickmeis, Thomas (2016). Extensive regulation of diurnal transcription and metabolism by glucocorticoids. PLoS Genetics, 12 (12) e1006512, e1006512. doi: 10.1371/journal.pgen.1006512 |
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2016 Journal Article Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolismJouffe, Celine, Gobet, Cedric, Martin, Eva, Metairon, Sylviane, Morin-Rivron, Delphine, Masoodi, Mojgan and Gachon, Frederic (2016). Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism. Scientific Reports, 6 (1) 24631. doi: 10.1038/srep24631 |
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2016 Journal Article USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational levelPouly, Daniel, Chenaux, Sebastien, Martin, Virginie, Babis, Maja, Koch, Rafael, Nagoshi, Emi, Katanaev, Vladimir L., Gachon, Frederic and Staub, Olivier (2016). USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational level. Plos One, 11 (1) e0145155, e0145155. doi: 10.1371/journal.pone.0145155 |
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2015 Journal Article Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liverAtger, Florian, Gobet, Cedric, Marquis, Julien, Martin, Eva, Wang, Jingkui, Weger, Benjamin, Lefebvre, Gregory, Descombes, Patrick, Naef, Felix and Gachon, Frederic (2015). Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver. Proceedings of the National Academy of Sciences of the United States of America, 112 (47), E6579-E6588. doi: 10.1073/pnas.1515308112 |
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2015 Journal Article Circadian dysfunction and obesity: is leptin the missing link?Dibner, Charna and Gachon, Frederic (2015). Circadian dysfunction and obesity: is leptin the missing link?. Cell Metabolism, 22 (3), 359-360. doi: 10.1016/j.cmet.2015.08.008 |
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2015 Journal Article Proteomics and circadian rhythms: it's all about signaling!Mauvoisin, Daniel, Dayon, Loic, Gachon, Frederic and Kussmann, Martin (2015). Proteomics and circadian rhythms: it's all about signaling!. Proteomics, 15 (2-3), 310-317. doi: 10.1002/pmic.201400187 |
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2014 Journal Article Local renal circadian clocks control fluid-electrolyte homeostasis and BPTokonami, Natsuko, Mordasini, David, Pradervand, Sylvain, Centeno, Gabriel, Jouffe, Celine, Maillard, Marc, Bonny, Olivier, Gachon, Frederic, Gomez, R. Ariel, Sequeira-Lopez, Maria Luisa S. and Firsov, Dmitri (2014). Local renal circadian clocks control fluid-electrolyte homeostasis and BP. Journal of the American Society of Nephrology, 25 (7), 1430-1439. doi: 10.1681/ASN.2013060641 |
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2014 Journal Article Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liverMauvoisin, Daniel, Wang, Jingkui, Jouffe, Celine, Martin, Eva, Atger, Florian, Waridel, Patrice, Quadroni, Manfredo, Gachon, Frederic and Naef, Felix (2014). Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver. Proceedings of the National Academy of Sciences of the United States of America, 111 (1), 167-172. doi: 10.1073/pnas.1314066111 |
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2014 Journal Article Chronopharmacology: new insights and therapeutic implicationsDallmann, Robert, Brown, Steven A. and Gachon, Frederic (2014). Chronopharmacology: new insights and therapeutic implications. Annual Review of Pharmacology and Toxicology, 54 (1), 339-361. doi: 10.1146/annurev-pharmtox-011613-135923 |
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2013 Journal Article The circadian clock coordinates ribosome biogenesisJouffe, Celine, Cretenet, Gaspard, Symul, Laura, Martin, Eva, Atger, Florian, Naef, Felix and Gachon, Frederic (2013). The circadian clock coordinates ribosome biogenesis. Plos Biology, 11 (1) e1001455, e1001455. doi: 10.1371/journal.pbio.1001455 |
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2011 Journal Article Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activityGachon, Frederic, Leuenberger, Nicolas, Claudel, Thierry, Gos, Pascal, Jouffe, Celine, Olela, Fabienne Fleury, du Jeu, Xavier de Mollerat, Wahli, Walter and Schibler, Ueli (2011). Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activity. Proceedings of the National Academy of Sciences of the United States of America, 108 (12), 4794-4799. doi: 10.1073/pnas.1002862108 |
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2011 Journal Article The role of circadian timing system on drug metabolism and detoxificationGachon, Frederic and Firsov, Dmitri (2011). The role of circadian timing system on drug metabolism and detoxification. Expert Opinion On Drug Metabolism and Toxicology, 7 (2), 147-158. doi: 10.1517/17425255.2011.544251 |
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2010 Journal Article Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEFWang, Qing, Maillard, Marc, Schibler, Ueli, Burnier, Michel and Gachon, Frederic (2010). Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 299 (4), R1013-R1019. doi: 10.1152/ajpregu.00241.2010 |
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2010 Journal Article Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?Gachon, Frederic and Bonnefont, Xavier (2010). Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?. Aging, 2 (2), 101-106. doi: 10.18632/aging.100123 |
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2010 Journal Article Circadian clock-coordinated 12 hr period rhythmic activation of the IRE1 alpha pathway controls lipid metabolism in mouse liverCretenet, Gaspard, Le Clech, Mikael and Gachon, Frederic (2010). Circadian clock-coordinated 12 hr period rhythmic activation of the IRE1 alpha pathway controls lipid metabolism in mouse liver. Cell Metabolism, 11 (1), 47-57. doi: 10.1016/j.cmet.2009.11.002 |
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2007 Journal Article Crosstalk between xenobiotics metabolism and circadian clockClaudel, Thierry, Cretenet, Gaspard, Saumet, Anne and Gachon, Frederic (2007). Crosstalk between xenobiotics metabolism and circadian clock. Febs Letters, 581 (19), 3626-3633. doi: 10.1016/j.febslet.2007.04.009 |
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2007 Journal Article Physiological function of PARbZip circadian clock-controlled transcription factorsGachon, Frederic (2007). Physiological function of PARbZip circadian clock-controlled transcription factors. Annals of Medicine, 39 (8), 562-571. doi: 10.1080/07853890701491034 |
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2006 Journal Article A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic geneBenito, Adalberto, Gutierrez, Olga, Pipaon, Carlos, Real, Pedro J., Gachon, Frederic, Ritchie, Alistair E. and Fernandez-Luna, Jose L. (2006). A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene. Journal of Biological Chemistry, 281 (50), 38351-38357. doi: 10.1074/jbc.M607004200 |
