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2024 Journal Article The effect of an improved ICU physical environment on outcomes and post-ICU recovery—a protocolTronstad, Oystein, Zangerl, Barbara, Patterson, Sue, Flaws, Dylan, Yerkovich, Stephanie, Szollosi, Irene, White, Nicole, Garcia-Hansen, Veronica, Leonard, Francisca Rodriguez, Weger, Benjamin D., Gachon, Frédéric, Brain, David, Lavana, Jayshree, Hodgson, Carol and Fraser, John F. (2024). The effect of an improved ICU physical environment on outcomes and post-ICU recovery—a protocol. Trials, 25 (1) 376. doi: 10.1186/s13063-024-08222-6 |
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2024 Journal Article Maternal high fat diet induces circadian clock-independent endocrine alterations impacting the metabolism of the offspringDing, Lu, Weger, Benjamin D., Liu, Jieying, Zhou, Liyuan, Lim, Yenkai, Wang, Dongmei, Xie, Ziyan, Liu, Jing, Ren, Jing, Zheng, Jia, Zhang, Qian, Yu, Miao, Weger, Meltem, Morrison, Mark, Xiao, Xinhua and Gachon, Frédéric (2024). Maternal high fat diet induces circadian clock-independent endocrine alterations impacting the metabolism of the offspring. iScience, 27 (7) 110343, 110343. doi: 10.1016/j.isci.2024.110343 |
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2024 Journal Article Steve Brown's legacy: tools to study the individual human molecular circadian clock and its regulationGachon, Frédéric (2024). Steve Brown's legacy: tools to study the individual human molecular circadian clock and its regulation. European Journal of Neuroscience, 60 (2), 3823-3827. doi: 10.1111/ejn.16335 |
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2023 Journal Article A gene-by-sex interaction contributes to liver disease susceptibility in womenGachon, Fred (2023). A gene-by-sex interaction contributes to liver disease susceptibility in women. Nature Medicine, 29 (10), 2422-2423. |
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2023 Journal Article Understanding circadian dynamics: current progress and future directions for chronobiology in drug discoveryWeger, Meltem, Weger, Benjamin D. and Gachon, Frédéric (2023). Understanding circadian dynamics: current progress and future directions for chronobiology in drug discovery. Expert Opinion on Drug Discovery, 18 (8), 893-901. doi: 10.1080/17460441.2023.2224554 |
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2023 Journal Article Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behaviorDelbès, Anne-Sophie, Quiñones, Mar, Gobet, Cédric, Castel, Julien, Denis, Raphaël G. P., Berthelet, Jérémy, Weger, Benjamin D., Challet, Etienne, Charpagne, Aline, Metairon, Sylviane, Piccand, Julie, Kraus, Marine, Rohde, Bettina H., Bial, John, Wilson, Elizabeth M., Vedin, Lise-Lotte, Minniti, Mirko E., Pedrelli, Matteo, Parini, Paolo, Gachon, Frédéric and Luquet, Serge (2023). Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior. Science Advances, 9 (20) eadf2982, 1-14. doi: 10.1126/sciadv.adf2982 |
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2023 Journal Article Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clockBignon, Yohan, Wigger, Leonore, Ansermet, Camille, Weger, Benjamin D., Lagarrigue, Sylviane, Centeno, Gabriel, Durussel, Fanny, Götz, Lou, Ibberson, Mark, Pradervand, Sylvain, Quadroni, Manfredo, Weger, Meltem, Amati, Francesca, Gachon, Frédéric and Firsov, Dmitri (2023). Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock. Journal of Clinical Investigation, 133 (8) e167133, 1-17. doi: 10.1172/JCI167133 |
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2022 Journal Article Voicing the need to consider sex-specific differences in researchMiguel-Aliaga, Irene, Vunjak-Novakovic, Gordana, Stephenson, Erin J., Gachon, Frederic, Milagre, Inês, Mills, Evanna, Rubin, Joshua B. and Kelava, Iva (2022). Voicing the need to consider sex-specific differences in research. Developmental Cell, 57 (24), 2675-2678. doi: 10.1016/j.devcel.2022.11.018 |
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2022 Journal Article Timing is everything: impact of development, ageing and circadian rhythm on macrophage functions in urinary tract infectionsWang, Alison S., Steers, Nicholas J., Parab, Adwaita R., Gachon, Frédéric, Sweet, Matthew J. and Mysorekar, Indira U. (2022). Timing is everything: impact of development, ageing and circadian rhythm on macrophage functions in urinary tract infections. Mucosal Immunology, 15 (6), 1-13. doi: 10.1038/s41385-022-00558-z |
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2022 Journal Article Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver diseaseJouffe, Céline, Weger, Benjamin D., Martin, Eva, Atger, Florian, Weger, Meltem, Gobet, Cédric, Ramnath, Divya, Charpagne, Aline, Morin-Rivron, Delphine, Powell, Elizabeth E., Sweet, Matthew J., Masoodi, Mojgan, Uhlenhaut, N. Henriette and Gachon, Frédéric (2022). Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease. Proceedings of the National Academy of Sciences, 119 (10) e2200083119, e2200083119. doi: 10.1073/pnas.2200083119 |
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2022 Journal Article The mechanisms and physiological consequences of diurnal hepatic cell size fluctuations: a brief reviewWeger, Meltem, Weger, Benjamin D. and Gachon, Frédéric (2022). The mechanisms and physiological consequences of diurnal hepatic cell size fluctuations: a brief review. Cellular Physiology and Biochemistry, 56 (S2), 1-11. doi: 10.33594/000000489 |
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2021 Journal Article Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetesAnsermet, Camille, Centeno, Gabriel, Bignon, Yohan, Ortiz, Daniel, Pradervand, Sylvain, Garcia, Andy, Menin, Laure, Gachon, Frédéric, Yoshihara, Hikari AI. and Firsov, Dmitri (2021). Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes. Kidney International, 101 (3), 563-573. doi: 10.1016/j.kint.2021.11.016 |
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2021 Journal Article The Insulin/Insulin‐like Growth Factor signaling connects metabolism with sexual differentiationWeger, Benjamin D. and Gachon, Frédéric (2021). The Insulin/Insulin‐like Growth Factor signaling connects metabolism with sexual differentiation. Acta Physiologica, 231 (3) e13576, e13576. doi: 10.1111/apha.13576 |
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2021 Journal Article Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythmsWeger, Benjamin D., Gobet, Cédric, David, Fabrice P. A., Atger, Florian, Martin, Eva, Phillips, Nicholas E., Charpagne, Aline, Weger, Meltem, Naef, Felix and Gachon, Frédéric (2021). Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms. Proceedings of the National Academy of Sciences, 118 (3) e2015803118, 1-12. doi: 10.1073/pnas.2015803118 |
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2020 Journal Article Neuronal activity regulates blood-brain barrier efflux transport through endothelial circadian genesPulido, Robert S., Munji, Roeben N., Chan, Tamara C., Quirk, Clare R., Weiner, Geoffrey A., Weger, Benjamin D., Rossi, Meghan J., Elmsaouri, Sara, Malfavon, Mario, Deng, Aaron, Profaci, Caterina P., Blanchette, Marie, Qian, Tongcheng, Foreman, Koji L., Shusta, Eric V., Gorman, Michael R., Gachon, Frédéric, Leutgeb, Stefan and Daneman, Richard (2020). Neuronal activity regulates blood-brain barrier efflux transport through endothelial circadian genes. Neuron, 108 (5), 937-952.e7. doi: 10.1016/j.neuron.2020.09.002 |
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2020 Journal Article Time to listen: circadian impact on auditory researchCederroth, Christopher, Gachon, Frédéric and Canlon, Barbara (2020). Time to listen: circadian impact on auditory research. Current Opinion in Physiology, 18, 95-99. doi: 10.1016/j.cophys.2020.09.005 |
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2020 Journal Article MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epibolyWeger, Meltem, Weger, Benjamin D, Schink, Andrea, Takamiya, Masanari, Stegmaier, Johannes, Gobet, Cédric, Parisi, Alice, Kobitski, Andrei Yu, Mertes, Jonas, Krone, Nils, Strähle, Uwe, Nienhaus, Gerd Ulrich, Mikut, Ralf, Gachon, Frédéric, Gut, Philipp and Dickmeis, Thomas (2020). MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly. eLife, 9 e57068, 1-35. doi: 10.7554/elife.57068 |
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2020 Journal Article Proteomics in circadian biologyMauvoisin, Daniel and Gachon, Frédéric (2020). Proteomics in circadian biology. Journal of Molecular Biology, 432 (12), 3565-3577. doi: 10.1016/j.jmb.2019.12.004 |
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2020 Journal Article Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liverGobet, Cédric, Weger, Benjamin Dieter, Marquis, Julien, Martin, Eva, Neelagandan, Nagammal, Gachon, Frédéric and Naef, Felix (2020). Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver. Proceedings of the National Academy of Sciences, 117 (17), 9630-9641. doi: 10.1073/pnas.1918145117 |
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2019 Journal Article At the intersection of microbiota and circadian clock: are sexual dimorphism and growth hormones the missing link to pathology? Circadian clock and microbiota: potential egffect on growth hormone and sexual developmentWeger, Benjamin D., Rawashdeh, Oliver and Gachon, Frédéric (2019). At the intersection of microbiota and circadian clock: are sexual dimorphism and growth hormones the missing link to pathology? Circadian clock and microbiota: potential egffect on growth hormone and sexual development. BioEssays, 41 (9) 1900059, e1900059. doi: 10.1002/bies.201900059 |
