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2020

Journal Article

Sulfoxide‐containing polymer‐coated nanoparticles demonstrate minimal protein fouling and improved blood circulation

Qiao, Ruirui, Fu, Changkui, Li, Yuhuan, Qi, Xiaole, Ni, Dalong, Nandakumar, Aparna, Siddiqui, Ghizal, Wang, Haiyan, Zhang, Zheng, Wu, Tingting, Zhong, Jian, Tang, Shi‐Yang, Pan, Shuaijun, Zhang, Cheng, Whittaker, Michael R., Engle, Jonathan W., Creek, Darren J., Caruso, Frank, Ke, Pu Chun, Cai, Weibo, Whittaker, Andrew K. and Davis, Thomas P. (2020). Sulfoxide‐containing polymer‐coated nanoparticles demonstrate minimal protein fouling and improved blood circulation. Advanced Science, 7 (13) 2000406, 2000406. doi: 10.1002/advs.202000406

Sulfoxide‐containing polymer‐coated nanoparticles demonstrate minimal protein fouling and improved blood circulation

2020

Journal Article

H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)-cholesteryl conjugates

Ercole, Francesca, Li, Yuhuan, Whittaker, Michael R., Davis, Thomas P. and Quinn, John F. (2020). H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)-cholesteryl conjugates. Journal of Materials Chemistry B, 8 (17), 3896-3907. doi: 10.1039/c9tb02614b

H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)-cholesteryl conjugates

2020

Journal Article

Design and preclinical evaluation of nanostars for the passive pretargeting of tumor tissue

Goos, Jeroen A.C.M., Davydova, Maria, Dilling, Thomas R., Cho, Andrew, Cornejo, Mike A., Gupta, Abhishek, Price, William S., Puttick, Simon, Whittaker, Michael R., Quinn, John F., Davis, Thomas P. and Lewis, Jason S. (2020). Design and preclinical evaluation of nanostars for the passive pretargeting of tumor tissue. Nuclear Medicine and Biology, 84-85, 63-72. doi: 10.1016/j.nucmedbio.2020.02.012

Design and preclinical evaluation of nanostars for the passive pretargeting of tumor tissue

2020

Journal Article

Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures

Leiske, Meike N., Walker, Julia A., Zia, Aadarash, Fletcher, Nicholas L., Thurecht, Kristofer J., Davis, Thomas P. and Kempe, Kristian (2020). Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures. Polymer Chemistry, 11 (16), 2799-2810. doi: 10.1039/d0py00304b

Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures

2020

Journal Article

The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability

Peng, Scott, Grace, Megan S., Gondin, Arisbel B., Retamal, Jeffri S., Dill, Larissa, Darby, William, Bunnett, Nigel W., Abogadie, Fe C., Carbone, Simona E., Tigani, Tara, Davis, Thomas P., Poole, Daniel P., Veldhuis, Nicholas A. and McIntyre, Peter (2020). The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability. Laboratory Investigation, 100 (8), 1057-1067. doi: 10.1038/s41374-020-0430-7

The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability

2020

Journal Article

Recent advances in molecular imaging of atherosclerotic plaques and thrombosis

Qiao, Ruirui, Huang, Xumin, Qin, Yu, Li, Yuhuan, Davis, Thomas P., Hagemeyer, Christoph E. and Gao, Mingyuan (2020). Recent advances in molecular imaging of atherosclerotic plaques and thrombosis. Nanoscale, 12 (15), 8040-8064. doi: 10.1039/d0nr00599a

Recent advances in molecular imaging of atherosclerotic plaques and thrombosis

2020

Journal Article

pH‐responsive polymers for improving the signal‐to‐noise ratio of hypoxia PET imaging with [18 F]Fluoromisonidazole

Goos, Jeroen A. C. M., Davydova, Maria, Lengkeek, Nigel, Greguric, Ivan, Whittaker, Michael R., Quinn, John F., Baell, Jonathan B., Lewis, Jason S. and Davis, Thomas P. (2020). pH‐responsive polymers for improving the signal‐to‐noise ratio of hypoxia PET imaging with [18 F]Fluoromisonidazole. Macromolecular Rapid Communications, 41 (11) 2000061, e2000061. doi: 10.1002/marc.202000061

pH‐responsive polymers for improving the signal‐to‐noise ratio of hypoxia PET imaging with [18 F]Fluoromisonidazole

2020

Journal Article

Multimodal nanoprobe for pancreatic beta cell detection and amyloidosis mitigation

Xin, Fangyun, Li, Yuhuan, Fu, Changkui, Javed, Ibrahim, Huang, Xumin, Schaschkow, Anais, Ribeiro, Rita S. Garcia, Gurzov, Esteban N., Davis, Thomas P., Zhang, Xiaoling, Ke, Pu Chun and Qjao, Ruirui (2020). Multimodal nanoprobe for pancreatic beta cell detection and amyloidosis mitigation. Chemistry of Materials, 32 (3), 1080-1088. doi: 10.1021/acs.chemmater.9b03841

Multimodal nanoprobe for pancreatic beta cell detection and amyloidosis mitigation

2020

Journal Article

Human plasma protein corona of Aβ amyloid and its impact on islet amyloid polypeptide cross-seeding

Nandakumar, Aparna, Xing, Yanting, Aranha, Ritchlynn R., Faridi, Ava, Kakinen, Aleksandr, Javed, Ibrahim, Koppel, Kairi, Pilkington, Emily H., Purcell, Anthony Wayne, Davis, Thomas P., Faridi, Pouya, Ding, Feng and Ke, Pu Chun (2020). Human plasma protein corona of Aβ amyloid and its impact on islet amyloid polypeptide cross-seeding. Biomacromolecules, 21 (2), 988-998. doi: 10.1021/acs.biomac.9b01650

Human plasma protein corona of Aβ amyloid and its impact on islet amyloid polypeptide cross-seeding

2020

Journal Article

Elucidating the effect of sequence and degree of polymerization on antimicrobial properties for block copolymers

Barbon, Stephanie M., Truong, Nghia P., Elliott, Alysha G., Cooper, Matthew A., Davis, Thomas P., Whittaker, Michael R., Hawker, Craig J. and Anastasaki, Athina (2020). Elucidating the effect of sequence and degree of polymerization on antimicrobial properties for block copolymers. Polymer Chemistry, 11 (1), 84-90. doi: 10.1039/c9py01435g

Elucidating the effect of sequence and degree of polymerization on antimicrobial properties for block copolymers

2020

Journal Article

Nonionic water-soluble and cytocompatible poly(amide acrylate)s

Mahmoud, Ayaat M., Morrow, Joshua P., Pizzi, David, Nanayakkara, Sepa, Davis, Thomas P., Saito, Kei and Kempe, Kristian (2020). Nonionic water-soluble and cytocompatible poly(amide acrylate)s. Macromolecules, 53 (2), 693-701. doi: 10.1021/acs.macromol.9b02267

Nonionic water-soluble and cytocompatible poly(amide acrylate)s

2020

Journal Article

Nanomaterial synthesis, an enabler of amyloidosis inhibition against human diseases

Andrikopoulos, Nicholas, Li, Yuhuan, Cecchetto, Luca, Nandakumar, Aparna, Da Ros, Tatiana, Davis, Thomas P., Velonia, Kelly and Ke, Pu Chun (2020). Nanomaterial synthesis, an enabler of amyloidosis inhibition against human diseases. Nanoscale, 12 (27), 14422-14440. doi: 10.1039/d0nr04273k

Nanomaterial synthesis, an enabler of amyloidosis inhibition against human diseases

2020

Journal Article

Half a century of amyloids: past, present and future

Ke, Pu Chun, Zhou, Ruhong, Serpell, Louise C., Riek, Roland, Knowles, Tuomas P. J., Lashuel, Hilal A., Gazit, Ehud, Hamley, Ian W., Davis, Thomas P., Fändrich, Marcus, Otzen, Daniel Erik, Chapman, Matthew R., Dobson, Christopher M., Eisenberg, David S. and Mezzenga, Raffaele (2020). Half a century of amyloids: past, present and future. Chemical Society Reviews, 49 (15), 5473-5509. doi: 10.1039/c9cs00199a

Half a century of amyloids: past, present and future

2020

Journal Article

Polymers with Dithiobenzoate End Groups Constitutively Release Hydrogen Sulfide upon Exposure to Cysteine and Homocysteine

Urquhart, Matthew C., Dao, Nam V., Ercole, Francesca, Boyd, Ben J., Davis, Thomas P., Whittaker, Michael R. and Quinn, John F. (2020). Polymers with Dithiobenzoate End Groups Constitutively Release Hydrogen Sulfide upon Exposure to Cysteine and Homocysteine. ACS Macro Letters, 9 (4), 553-557. doi: 10.1021/acsmacrolett.0c00066

Polymers with Dithiobenzoate End Groups Constitutively Release Hydrogen Sulfide upon Exposure to Cysteine and Homocysteine

2020

Journal Article

Delivery of polymeric nanostars for molecular imaging and endoradiotherapy through the enhanced permeability and retention (EPR) effect

Goos, Jeroen A. C. M., Cho, Andrew, Carter, Lukas M., Dilling, Thomas R., Davydova, Maria, Mandleywala, Komal, Puttick, Simon, Gupta, Abhishek, Price, William S., Quinn, John F., Whittaker, Michael R., Lewis, Jason S. and Davis, Thomas P. (2020). Delivery of polymeric nanostars for molecular imaging and endoradiotherapy through the enhanced permeability and retention (EPR) effect. Theranostics, 10 (2), 567-584. doi: 10.7150/thno.36777

Delivery of polymeric nanostars for molecular imaging and endoradiotherapy through the enhanced permeability and retention (EPR) effect

2020

Journal Article

Poly(2-isopropenyl-2-oxazoline) – a structural analogue to poly(vinyl azlactone) with Orthogonal Reactivity

Leiske, Meike N., Mahmoud, Ayaat M., Warne, Nicole M., Goos, Jeroen A. C. M., Pascual, Sagrario, Montembault, Véronique, Fontaine, Laurent, Davis, Thomas P., Whittaker, Michael R. and Kempe, Kristian (2020). Poly(2-isopropenyl-2-oxazoline) – a structural analogue to poly(vinyl azlactone) with Orthogonal Reactivity. Polymer Chemistry, 11 (35), 5681-5692. doi: 10.1039/d0py00861c

Poly(2-isopropenyl-2-oxazoline) – a structural analogue to poly(vinyl azlactone) with Orthogonal Reactivity

2020

Journal Article

Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis

Li, Yuhuan, Xin, Fangyun, Hu, Jinming, Jagdale, Shweta, Davis, Thomas P., Hagemeyer, Christoph E. and Qiao, Ruirui (2020). Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis. Polymer Chemistry, 11 (5), 1010-1017. doi: 10.1039/c9py01568j

Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis

2020

Journal Article

pH-Responsive copolymer micelles to enhance itraconazole efficacy against Candida albicans biofilms

Albayaty, Yassamin N., Thomas, Nicky, Ramírez-García, Paulina D., Davis, Thomas P., Quinn, John F., Whittaker, Michael R. and Prestidge, Clive A. (2020). pH-Responsive copolymer micelles to enhance itraconazole efficacy against Candida albicans biofilms. Journal of Materials Chemistry B, 8 (8), 1672-1681. doi: 10.1039/c9tb02586c

pH-Responsive copolymer micelles to enhance itraconazole efficacy against Candida albicans biofilms

2020

Journal Article

Nanosilver mitigates biofilm formation via FapC amyloidosis inhibition

Huma, Zil-e, Javed, Ibrahim, Zhang, Zhenzhen, Bilal, Hajira, Sun, Yunxiang, Hussain, Syed Zajif, Davis, Thomas P., Otzen, Daniel E., Landersdorfer, Cornelia B., Ding, Feng, Hussain, Irshad and Ke, Pu Chun (2020). Nanosilver mitigates biofilm formation via FapC amyloidosis inhibition. Small, 16 (21) 1906674, e1906674. doi: 10.1002/smll.201906674

Nanosilver mitigates biofilm formation via FapC amyloidosis inhibition

2019

Journal Article

Engineering organic/inorganic nanohybrids through RAFT polymerization for biomedical applications

Huang, Xumin, Hu, Jinming, Li, Yuhuan, Xin, Fangyun, Qiao, Ruirui and Davis, Thomas P. (2019). Engineering organic/inorganic nanohybrids through RAFT polymerization for biomedical applications. Biomacromolecules, 20 (12), 4243-4257. doi: 10.1021/acs.biomac.9b01158

Engineering organic/inorganic nanohybrids through RAFT polymerization for biomedical applications