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2019 Journal Article An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platformGrace, James L., Amado, Maite, Reid, Janet C., Elliott, Alysha G., Landersdorfer, Cornelia B., Truong, Nghia P., Kempe, Kristian, Cooper, Matthew A., Davis, Thomas P., Montembault, Véronique, Pascual, Sagrario, Fontaine, Laurent, Velkov, Tony, Quinn, John F. and Whittaker, Michael R. (2019). An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform. Journal of Materials Chemistry B, 7 (43), 6796-6809. doi: 10.1039/c9tb01624d |
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2019 Journal Article Polymer-assisted magnetic nanoparticle assemblies for biomedical applicationsLi, Yuhuan, Wang, Nan, Huang, Xumin, Li, Fangyuan, Davis, Thomas P., Qiao, Ruirui and Ling, Daishun (2019). Polymer-assisted magnetic nanoparticle assemblies for biomedical applications. ACS Applied Bio Materials, 3 (1), 121-142. doi: 10.1021/acsabm.9b00896 |
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2019 Journal Article Development of a shape-controlled H 2 S delivery system using epoxide-functional nanoparticlesYu, Sul Hwa, Esser, Lars, Khor, Song Yang, Senyschyn, Danielle, Veldhuis, Nicholas A., Whittaker, Michael R., Ercole, Francesca, Davis, Thomas P. and Quinn, John F. (2019). Development of a shape-controlled H 2 S delivery system using epoxide-functional nanoparticles. Journal of Polymer Science, Part A: Polymer Chemistry, 57 (18) pola.29382, 1982-1993. doi: 10.1002/pola.29382 |
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2019 Journal Article Single-Molecular Heteroamyloidosis of Human Islet Amyloid PolypeptideKakinen, Aleksandr, Xing, Yanting, Hegoda Arachchi, Nuwan, Javed, Ibrahim, Feng, Lei, Faridi, Ava, Douek, Alon M., Sun, Yunxiang, Kaslin, Jan, Davis, Thomas P., Higgins, Michael J., Ding, Feng and Ke, Pu Chun (2019). Single-Molecular Heteroamyloidosis of Human Islet Amyloid Polypeptide. Nano Letters, 19 (9), 6535-6546. doi: 10.1021/acs.nanolett.9b02771 |
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2019 Journal Article Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategyJaved, Ibrahim, Peng, Guotao, Xing, Yanting, Yu, Tianyu, Zhao, Mei, Kakinen, Aleksandr, Faridi, Ava, Parish, Clare L., Ding, Feng, Davis, Thomas P., Ke, Pu Chun and Lin, Sijie (2019). Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy. Nature Communications, 10 (1) 3780, 3780. doi: 10.1038/s41467-019-11762-0 |
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2019 Journal Article Carboxylated Cy5-labeled comb polymers passively diffuse the cell membrane and target mitochondriaMahmoud, Ayaat M., de Jongh, Patrick A. J. M., Briere, Sibylle, Chen, Moore, Nowell, Cameron J., Johnston, Angus P. R., Davis, Thomas P., Haddleton, David M. and Kempe, Kristian (2019). Carboxylated Cy5-labeled comb polymers passively diffuse the cell membrane and target mitochondria. ACS Applied Materials and Interfaces, 11 (34), 31302-31310. doi: 10.1021/acsami.9b09395 |
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2019 Journal Article Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACoreSun, Yunxiang, Kakinen, Aleksandr, Zhang, Chi, Yang, Ye, Faridi, Ava, Davis, Thomas P., Cao, Weiguo, Ke, Pu Chun and Ding, Feng (2019). Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore. Nanoscale, 11 (24), 11933-11945. doi: 10.1039/c9nr02407g |
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2019 Journal Article Mitigation of amyloidosis with nanomaterialsKe, Pu Chun, Pilkington, Emily H., Sun, Yunxiang, Javed, Ibrahim, Kakinen, Aleksandr, Peng, Guotao, Ding, Feng and Davis, Thomas P. (2019). Mitigation of amyloidosis with nanomaterials. Advanced Materials, 32 (18) 1901690, 1901690. doi: 10.1002/adma.201901690 |
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2019 Journal Article Intra-articular treatment of osteoarthritis with diclofenac-conjugated polymer reduces inflammation and painSulistio, Adrian, Mansfeld, Friederike M., Reyes-Ortega, Felisa, D'Souza, Asha M., Ng, Sarah M. Y., Birkett, Stephen, Blencowe, Anton, Qiao, Greg G., Little, Christopher B., Shu, Cindy C., Bendele, Alison M., Valade, David, Donohue, Andrew C., Quinn, John F., Whittaker, Michael R., Davis, Thomas P. and Tait, Russell J. (2019). Intra-articular treatment of osteoarthritis with diclofenac-conjugated polymer reduces inflammation and pain. ACS Applied Bio Materials, 2 (7), 2822-2832. doi: 10.1021/acsabm.9b00232 |
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2019 Journal Article A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunctionSomers, Klaartje, Wen, Victoria W., Middlemiss, Shiloh M. C., Osborne, Brenna, Forgham, Helen, Jung, MoonSun, Karsa, Mawar, Clifton, Molly, Bongers, Angelika, Gao, Jixuan, Mayoh, Chelsea, Raoufi-Rad, Newsha, Kusnadi, Eric P., Hannan, Kate M., Scott, David A., Kwek, Alan, Liu, Bing, Flemming, Claudia, Chudakova, Daria A., Pandher, Ruby, Failes, Tim W., Lim, James, Angeli, Andrea, Osterman, Andrei L., Imamura, Toshihiko, Kees, Ursula R., Supuran, Claudiu T., Pearson, Richard B., Hannan, Ross D. ... Henderson, Michelle J. (2019). A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene, 38 (20), 3824-3842. doi: 10.1038/s41388-018-0666-5 |
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2019 Journal Article Amyloid self-assembly of hIAPP8-20 via the accumulation of helical oligomers, α-helix to β-sheet transition, and formation of β-barrel intermediatesSun, Yunxiang, Kakinen, Aleksandr, Xing, Yanting, Faridi, Pouya, Nandakumar, Aparna, Purcell, Anthony W., Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2019). Amyloid self-assembly of hIAPP8-20 via the accumulation of helical oligomers, α-helix to β-sheet transition, and formation of β-barrel intermediates. Small, 15 (18) 1805166, 1805166. doi: 10.1002/smll.201805166 |
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2019 Journal Article Functional brush poly(2-ethyl-2-oxazine)s: synthesis by CROP and RAFT, thermoresponsiveness and grafting onto iron oxide nanoparticlesKlein, Tobias, Parkin, Joshua, de Jongh, Patrick A. J. M., Esser, Lars, Sepehrizadeh, Tara, Zheng, Gang, De Veer, Michael, Alt, Karen, Hagemeyer, Christoph E., Haddleton, David M., Davis, Thomas P., Thelakkat, Mukundan and Kempe, Kristian (2019). Functional brush poly(2-ethyl-2-oxazine)s: synthesis by CROP and RAFT, thermoresponsiveness and grafting onto iron oxide nanoparticles. Macromolecular Rapid Communications, 40 (10) 1800911. doi: 10.1002/marc.201800911 |
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2019 Journal Article Rapid assessment of nanoparticle extravasation in a microfluidic tumor modelVu, Mai N., Rajasekhar, Pradeep, Poole, Daniel P., Khor, Song Yang, Truong, Nghia P., Nowell, Cameron J., Quinn, John F., Whittaker, Michael, Veldhuis, Nicholas A. and Davis, Thomas P. (2019). Rapid assessment of nanoparticle extravasation in a microfluidic tumor model. ACS Applied Nano Materials, 2 (4), 1844-1856. doi: 10.1021/acsanm.8b02056 |
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2019 Journal Article Probing the aggregation and immune response of human islet amyloid polypeptides with ligand-stabilized gold nanoparticlesJaved, Ibrahim, He, Jiacheng, Kakinen, Aleksandr, Faridi, Ava, Yang, Wen, Davis, Thomas P., Ke, Pu Chun and Chen, Pengyu (2019). Probing the aggregation and immune response of human islet amyloid polypeptides with ligand-stabilized gold nanoparticles. ACS Applied Materials and Interfaces, 11 (11), 10462-10471. doi: 10.1021/acsami.8b19506 |
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2019 Journal Article Synthesis and identification of novel pyridazinylpyrazolone based diazo compounds as inhibitors of human islet amyloid polypeptide aggregationBin Farrukh, Syed Usama, Javed, Ibrahim, Ather, Abdul Qayyum, Emwas, Abdul-Hamid, Alazmi, Meshari, Gao, Xin, Chotana, Ghayoor Abbas, Davis, Thomas P., Ke, Pu Chun and Saleem, Rahman Shah Zaib (2019). Synthesis and identification of novel pyridazinylpyrazolone based diazo compounds as inhibitors of human islet amyloid polypeptide aggregation. Bioorganic Chemistry, 84, 339-346. doi: 10.1016/j.bioorg.2018.11.039 |
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2019 Journal Article Functional liquid metal nanoparticles produced by liquid-based nebulizationTang, Shi-Yang, Qiao, Ruirui, Lin, Yiliang, Li, Yuhuan, Zhao, Qianbin, Yuan, Dan, Yun, Guolin, Guo, Jinhong, Dickey, Michael D., Huang, Tony Jun, Davis, Thomas P., Kalantar-Zadeh, Kourosh and Li, Weihua (2019). Functional liquid metal nanoparticles produced by liquid-based nebulization. Advanced Materials Technologies, 4 (2) 1800420, 1-9. doi: 10.1002/admt.201800420 |
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2019 Journal Article Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptideSun, Yunxiang, Kakinen, Aleksandr, Xing, Yanting, Pilkington, Emily H., Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2019). Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1865 (2), 434-444. doi: 10.1016/j.bbadis.2018.11.021 |
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2019 Journal Article Tuning the structure, stability, and responsivity of polymeric arsenical nanoparticles using polythiol cross-linkersTanaka, Joji, Moriceau, Guillaume, Cook, Alexander, Kerr, Andrew, Zhang, Junliang, Peltier, Raoul, Perrier, Sebastien, Davis, Thomas P. and Wilson, Paul (2019). Tuning the structure, stability, and responsivity of polymeric arsenical nanoparticles using polythiol cross-linkers. Macromolecules, 52 (3), 992-1003. doi: 10.1021/acs.macromol.8b02459 |
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2019 Journal Article Physical and toxicological profiles of human IAPP amyloids and plaquesKakinen, Aleksandr, Sun, Yunxiang, Javed, Ibrahim, Faridi, Ava, Pilkington, Emily H., Faridi, Pouya, Purcell, Anthony W., Zhou, Ruhong, Ding, Feng, Lin, Sijie, Ke, Pu Chun and Davis, Thomas P. (2019). Physical and toxicological profiles of human IAPP amyloids and plaques. Science Bulletin, 64 (1), 26-35. doi: 10.1016/j.scib.2018.11.012 |
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2019 Journal Article Polymeric arsenicals as scaffolds for functional and responsive hydrogelsTanaka, Joji, Song, Ji-Inn, Lunn, Andrew M., Hand, Rachel A., Häkkinen, Satu, Schiller, Tara L., Perrier, Sébastien, Davis, Thomas P. and Wilson, Paul (2019). Polymeric arsenicals as scaffolds for functional and responsive hydrogels. Journal of Materials Chemistry B, 7 (27), 4263-4271. doi: 10.1039/c8tb02569j |
