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2021

Journal Article

Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood

Leiske, Meike N., Lai, May, Amarasena, Thakshila, Davis, Thomas P., Thurecht, Kristofer J., Kent, Stephen J. and Kempe, Kristian (2021). Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood. Biomaterials, 274 120843, 120843. doi: 10.1016/j.biomaterials.2021.120843

Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood

2021

Journal Article

Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice

Retamal, Jeffri S., Grace, Megan S., Dill, Larissa K., Ramirez-Garcia, Paulina, Peng, Scott, Gondin, Arisbel B., Bennetts, Felix, Alvi, Sadia, Rajasekhar, Pradeep, Almazi, Juhura G., Carbone, Simona E., Bunnett, Nigel W., Davis, Thomas P., Veldhuis, Nicholas A., Poole, Daniel P. and McIntyre, Peter (2021). Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice. Laboratory Investigation, 101 (7), 851-864. doi: 10.1038/s41374-021-00593-7

Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice

2021

Journal Article

Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidity

Li, Yuhuan, Tang, Huayuan, Zhu, Houjuan, Kakinen, Aleksandr, Wang, Di, Andrikopoulos, Nicholas, Sun, Yunxiang, Nandakumar, Aparna, Kwak, Eunbi, Davis, Thomas P., Leong, David Tai, Ding, Feng and Ke, Pu Chun (2021). Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidity. ACS Applied Materials and Interfaces, 13 (25) acsami.1c06478, 29936-29948. doi: 10.1021/acsami.1c06478

Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidity

2021

Journal Article

Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid beta

Sun, Yunxiang, Kakinen, Aleksandr, Wan, Xulin, Moriarty, Niamh, Hunt, Cameron P.J., Li, Yuhuan, Andrikopoulos, Nicholas, Nandakumar, Aparna, Davis, Thomas P., Parish, Clare L., Song, Yang, Ke, Pu Chun and Ding, Feng (2021). Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid beta. Nano Today, 38 101125, 101125. doi: 10.1016/j.nantod.2021.101125

Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid beta

2021

Journal Article

Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity

Vu, Mai N., Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Esterbauer, Robyn, Davis, Thomas P., Truong, Nghia P., Wheatley, Adam K. and Kent, Stephen J. (2021). Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity. Advanced Healthcare Materials, 10 (10) 2002142, 1-12. doi: 10.1002/adhm.202002142

Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity

2021

Journal Article

Polymeric micelles with anti-virulence activity against Candida albicans in a single- and dual-species biofilm

Albayaty, Yassamin N., Thomas, Nicky, Ramirez-Garcia, Paulina D., Davis, Thomas P., Quinn, John F., Whittaker, Michael R. and Prestidge, Clive A. (2021). Polymeric micelles with anti-virulence activity against Candida albicans in a single- and dual-species biofilm. Drug Delivery and Translational Research, 11 (4), 1586-1597. doi: 10.1007/s13346-021-00943-4

Polymeric micelles with anti-virulence activity against Candida albicans in a single- and dual-species biofilm

2021

Journal Article

Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s

Finnegan, John R., Pilkington, Emily H., Alt, Karen, Rahim, Md. Arifur, Kent, Stephen J., Davis, Thomas P. and Kempe, Kristian (2021). Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s. Chemical Science, 12 (21), 1-11. doi: 10.1039/d1sc00938a

Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s

2021

Journal Article

From influenza to COVID-19: lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases

Pilkington, Emily H., Suys, Estelle J.A., Trevaskis, Natalie L., Wheatley, Adam K., Zukancic, Danijela, Algarni, Azizah, Al-Wassiti, Hareth, Davis, Thomas P., Pouton, Colin W., Kent, Stephen J. and Truong, Nghia P. (2021). From influenza to COVID-19: lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases. Acta Biomaterialia, 131, 16-40. doi: 10.1016/j.actbio.2021.06.023

From influenza to COVID-19: lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases

2021

Journal Article

In vitro and in vivo models for anti-amyloidosis nanomedicines

Kakinen, Aleksandr, Javed, Ibrahim, Davis, Thomas P. and Ke, Pu Chun (2021). In vitro and in vivo models for anti-amyloidosis nanomedicines. Nanoscale Horizons, 6 (2), 95-119. doi: 10.1039/d0nh00548g

In vitro and in vivo models for anti-amyloidosis nanomedicines

2021

Journal Article

Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model

Dao, Nam V., Ercole, Francesca, Urquhart, Matthew C., Kaminskas, Lisa M., Nowell, Cameron J., Davis, Thomas P., Sloan, Erica K., Whittaker, Michael R. and Quinn, John F. (2021). Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model. Biomaterials Science, 9 (3), 835-846. doi: 10.1039/d0bm01544j

Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model

2021

Journal Article

Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes

Xu, Xin, Huang, Xumin, Chang, Yixin, Yu, Ye, Zhao, Jiacheng, Isahak, Naatasha, Teng, Jisi, Qiao, Ruirui, Peng, Hui, Zhao, Chun-Xia, Davis, Thomas P., Fu, Changkui and Whittaker, Andrew K. (2021). Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes. Biomacromolecules, 22 (2), 330-339. doi: 10.1021/acs.biomac.0c01193

Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes

2021

Journal Article

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

Mai, Quynh N., Shenoy, Priyank, Quach, Tim, Retamal, Jeffri S., Gondin, Arisbel B., Yeatman, Holly R., Aurelio, Luigi, Conner, Joshua W., Poole, Daniel P., Canals, Meritxell, Nowell, Cameron J., Graham, Bim, Davis, Thomas P., Briddon, Stephen J., Hill, Stephen J., Porter, Christopher J.H., Bunnett, Nigel W., Halls, Michelle L. and Veldhuis, Nicholas A. (2021). A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes. Journal of Biological Chemistry, 296 100345, 100345. doi: 10.1016/J.JBC.2021.100345

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

2020

Journal Article

Amyloid aggregation under the lens of liquid–liquid phase separation

Xing, Yanting, Nandakumar, Aparna, Kakinen, Aleksandr, Sun, Yunxiang, Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2020). Amyloid aggregation under the lens of liquid–liquid phase separation. The Journal of Physical Chemistry Letters, 12 (1), 368-378. doi: 10.1021/acs.jpclett.0c02567

Amyloid aggregation under the lens of liquid–liquid phase separation

2020

Journal Article

Trisulfide-bearing PEG brush polymers donate hydrogen sulfide and ameliorate cellular oxidative stress

Dao, Nam V., Ercole, Francesca, Kaminskas, Lisa M., Davis, Thomas P., Sloan, Erica K., Whittaker, Michael R. and Quinn, John F. (2020). Trisulfide-bearing PEG brush polymers donate hydrogen sulfide and ameliorate cellular oxidative stress. Biomacromolecules, 21 (12), 5292-5305. doi: 10.1021/acs.biomac.0c01347

Trisulfide-bearing PEG brush polymers donate hydrogen sulfide and ameliorate cellular oxidative stress

2020

Journal Article

The membrane axis of Alzheimer's nanomedicine

Li, Yuhuan, Tang, Huayuan, Andrikopoulos, Nicholas, Javed, Ibrahim, Cecchetto, Luca, Nandakumar, Aparna, Kakinen, Aleksandr, Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2020). The membrane axis of Alzheimer's nanomedicine. Advanced NanoBiomed Research, 1 (1) 2000040, 2000040. doi: 10.1002/anbr.202000040

The membrane axis of Alzheimer's nanomedicine

2020

Journal Article

Amyloidosis inhibition, a new frontier of the protein corona

Chen, Pengyu, Ding, Feng, Cai, Rong, Javed, Ibrahim, Yang, Wen, Zhang, Zhenzhen, Li, Yuhuan, Davis, Thomas P., Ke, Pu Chun and Chen, Chunying (2020). Amyloidosis inhibition, a new frontier of the protein corona. Nano Today, 35 100937, 100937. doi: 10.1016/j.nantod.2020.100937

Amyloidosis inhibition, a new frontier of the protein corona

2020

Journal Article

Biomedical applications of liquid metal nanoparticles: a critical review

Li, Haiyue, Qiao, Ruirui, Davis, Thomas P. and Tang, Shi-Yang (2020). Biomedical applications of liquid metal nanoparticles: a critical review. Biosensors, 10 (12) 196, 196. doi: 10.3390/bios10120196

Biomedical applications of liquid metal nanoparticles: a critical review

2020

Journal Article

Implications of the human gut–brain and gut–cancer axes for future nanomedicine

Javed, Ibrahim, Cui, Xuejing, Wang, Xiaoyu, Mortimer, Monika, Andrikopoulos, Nikolaos, Li, Yuhuan, Davis, Thomas P., Zhao, Yuliang, Ke, Pu Chun and Chen, Chunying (2020). Implications of the human gut–brain and gut–cancer axes for future nanomedicine. ACS Nano, 14 (11), 14391-14416. doi: 10.1021/acsnano.0c07258

Implications of the human gut–brain and gut–cancer axes for future nanomedicine

2020

Journal Article

Accelerated amyloid beta pathogenesis by bacterial amyloid FapC

Javed, Ibrahim, Zhang, Zhenzhen, Adamcik, Jozef, Andrikopoulos, Nicholas, Li, Yuhuan, Otzen, Daniel E., Lin, Sijie, Mezzenga, Raffaele, Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2020). Accelerated amyloid beta pathogenesis by bacterial amyloid FapC. Advanced Science, 7 (18) 2001299, 2001299. doi: 10.1002/advs.202001299

Accelerated amyloid beta pathogenesis by bacterial amyloid FapC

2020

Journal Article

Tuning cellular interactions of carboxylic acid-side-chain-containing polyacrylates: the role of cyanine dye label and side-chain type

Mahmoud, Ayaat M., Morrow, Joshua P., Pizzi, David, Azizah, Ailsa M., Davis, Thomas P., Tabor, Rico F. and Kempe, Kristian (2020). Tuning cellular interactions of carboxylic acid-side-chain-containing polyacrylates: the role of cyanine dye label and side-chain type. Biomacromolecules, 21 (8) acs.biomac.0c00244, 3007-3016. doi: 10.1021/acs.biomac.0c00244

Tuning cellular interactions of carboxylic acid-side-chain-containing polyacrylates: the role of cyanine dye label and side-chain type