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2021 Journal Article A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomesMai, Quynh N., Shenoy, Priyank, Quach, Tim, Retamal, Jeffri S., Gondin, Arisbel B., Yeatman, Holly R., Aurelio, Luigi, Conner, Joshua W., Poole, Daniel P., Canals, Meritxell, Nowell, Cameron J., Graham, Bim, Davis, Thomas P., Briddon, Stephen J., Hill, Stephen J., Porter, Christopher J.H., Bunnett, Nigel W., Halls, Michelle L. and Veldhuis, Nicholas A. (2021). A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes. Journal of Biological Chemistry, 296 100345, 100345. doi: 10.1016/J.JBC.2021.100345 |
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2020 Journal Article Amyloid aggregation under the lens of liquid–liquid phase separationXing, Yanting, Nandakumar, Aparna, Kakinen, Aleksandr, Sun, Yunxiang, Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2020). Amyloid aggregation under the lens of liquid–liquid phase separation. The Journal of Physical Chemistry Letters, 12 (1), 368-378. doi: 10.1021/acs.jpclett.0c02567 |
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2020 Journal Article Trisulfide-bearing PEG brush polymers donate hydrogen sulfide and ameliorate cellular oxidative stressDao, Nam V., Ercole, Francesca, Kaminskas, Lisa M., Davis, Thomas P., Sloan, Erica K., Whittaker, Michael R. and Quinn, John F. (2020). Trisulfide-bearing PEG brush polymers donate hydrogen sulfide and ameliorate cellular oxidative stress. Biomacromolecules, 21 (12), 5292-5305. doi: 10.1021/acs.biomac.0c01347 |
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2020 Journal Article The membrane axis of Alzheimer's nanomedicineLi, Yuhuan, Tang, Huayuan, Andrikopoulos, Nicholas, Javed, Ibrahim, Cecchetto, Luca, Nandakumar, Aparna, Kakinen, Aleksandr, Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2020). The membrane axis of Alzheimer's nanomedicine. Advanced NanoBiomed Research, 1 (1) 2000040, 2000040. doi: 10.1002/anbr.202000040 |
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2020 Journal Article Amyloidosis inhibition, a new frontier of the protein coronaChen, Pengyu, Ding, Feng, Cai, Rong, Javed, Ibrahim, Yang, Wen, Zhang, Zhenzhen, Li, Yuhuan, Davis, Thomas P., Ke, Pu Chun and Chen, Chunying (2020). Amyloidosis inhibition, a new frontier of the protein corona. Nano Today, 35 100937, 100937. doi: 10.1016/j.nantod.2020.100937 |
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2020 Journal Article Biomedical applications of liquid metal nanoparticles: a critical reviewLi, Haiyue, Qiao, Ruirui, Davis, Thomas P. and Tang, Shi-Yang (2020). Biomedical applications of liquid metal nanoparticles: a critical review. Biosensors, 10 (12) 196, 196. doi: 10.3390/bios10120196 |
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2020 Journal Article Implications of the human gut–brain and gut–cancer axes for future nanomedicineJaved, Ibrahim, Cui, Xuejing, Wang, Xiaoyu, Mortimer, Monika, Andrikopoulos, Nikolaos, Li, Yuhuan, Davis, Thomas P., Zhao, Yuliang, Ke, Pu Chun and Chen, Chunying (2020). Implications of the human gut–brain and gut–cancer axes for future nanomedicine. ACS Nano, 14 (11), 14391-14416. doi: 10.1021/acsnano.0c07258 |
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2020 Journal Article Accelerated amyloid beta pathogenesis by bacterial amyloid FapCJaved, Ibrahim, Zhang, Zhenzhen, Adamcik, Jozef, Andrikopoulos, Nicholas, Li, Yuhuan, Otzen, Daniel E., Lin, Sijie, Mezzenga, Raffaele, Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2020). Accelerated amyloid beta pathogenesis by bacterial amyloid FapC. Advanced Science, 7 (18) 2001299, 2001299. doi: 10.1002/advs.202001299 |
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2020 Journal Article Tuning cellular interactions of carboxylic acid-side-chain-containing polyacrylates: the role of cyanine dye label and side-chain typeMahmoud, Ayaat M., Morrow, Joshua P., Pizzi, David, Azizah, Ailsa M., Davis, Thomas P., Tabor, Rico F. and Kempe, Kristian (2020). Tuning cellular interactions of carboxylic acid-side-chain-containing polyacrylates: the role of cyanine dye label and side-chain type. Biomacromolecules, 21 (8) acs.biomac.0c00244, 3007-3016. doi: 10.1021/acs.biomac.0c00244 |
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2020 Journal Article Cellular interactions of liposomes and PISA nanoparticles during human blood flow in a microvascular networkVu, Mai N., Kelly, Hannah G., Wheatley, Adam K., Peng, Scott, Pilkington, Emily H., Veldhuis, Nicholas A., Davis, Thomas P., Kent, Stephen J. and Truong, Nghia P. (2020). Cellular interactions of liposomes and PISA nanoparticles during human blood flow in a microvascular network. Small, 16 (33) 2002861, 2002861. doi: 10.1002/smll.202002861 |
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2020 Journal Article Elevated amyloidoses of human IAPP and amyloid beta by lipopolysaccharide and their mitigation by carbon quantum dotsKoppel, Kairi, Tang, Huayuan, Javed, Ibrahim, Parsa, Mehrdad, Mortimer, Monika, Davis, Thomas P., Lin, Sijie, Chaffee, Alan L., Ding, Feng and Ke, Pu Chun (2020). Elevated amyloidoses of human IAPP and amyloid beta by lipopolysaccharide and their mitigation by carbon quantum dots. Nanoscale, 12 (23), 12317-12328. doi: 10.1039/d0nr02710c |
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2020 Journal Article Stimuli-responsive nano-assemblies for remotely controlled drug deliveryLi, Fangyuan, Qin, Yu, Lee, Jiyoung, Liao, Hongwei, Wang, Nan, Davis, Thomas P., Qiao, Ruirui and Ling, Daishun (2020). Stimuli-responsive nano-assemblies for remotely controlled drug delivery. Journal of Controlled Release, 322, 566-592. doi: 10.1016/j.jconrel.2020.03.051 |
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2020 Journal Article Proteins conjugated with sulfoxide-containing polymers show reduced macrophage cellular uptake and improved pharmacokineticsYu, Ye, Xu, Weizhi, Huang, Xumin, Xu, Xin, Qiao, Ruirui, Li, Yuhuan, Han, Felicity, Peng, Hui, Davis, Thomas P., Fu, Changkui and Whittaker, Andrew K. (2020). Proteins conjugated with sulfoxide-containing polymers show reduced macrophage cellular uptake and improved pharmacokinetics. ACS Macro Letters, 9 (6), 799-805. doi: 10.1021/acsmacrolett.0c00291 |
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2020 Journal Article Sulfoxide‐containing polymer‐coated nanoparticles demonstrate minimal protein fouling and improved blood circulationQiao, Ruirui, Fu, Changkui, Li, Yuhuan, Qi, Xiaole, Ni, Dalong, Nandakumar, Aparna, Siddiqui, Ghizal, Wang, Haiyan, Zhang, Zheng, Wu, Tingting, Zhong, Jian, Tang, Shi‐Yang, Pan, Shuaijun, Zhang, Cheng, Whittaker, Michael R., Engle, Jonathan W., Creek, Darren J., Caruso, Frank, Ke, Pu Chun, Cai, Weibo, Whittaker, Andrew K. and Davis, Thomas P. (2020). Sulfoxide‐containing polymer‐coated nanoparticles demonstrate minimal protein fouling and improved blood circulation. Advanced Science, 7 (13) 2000406, 2000406. doi: 10.1002/advs.202000406 |
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2020 Journal Article H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)-cholesteryl conjugatesErcole, Francesca, Li, Yuhuan, Whittaker, Michael R., Davis, Thomas P. and Quinn, John F. (2020). H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)-cholesteryl conjugates. Journal of Materials Chemistry B, 8 (17), 3896-3907. doi: 10.1039/c9tb02614b |
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2020 Journal Article Design and preclinical evaluation of nanostars for the passive pretargeting of tumor tissueGoos, Jeroen A.C.M., Davydova, Maria, Dilling, Thomas R., Cho, Andrew, Cornejo, Mike A., Gupta, Abhishek, Price, William S., Puttick, Simon, Whittaker, Michael R., Quinn, John F., Davis, Thomas P. and Lewis, Jason S. (2020). Design and preclinical evaluation of nanostars for the passive pretargeting of tumor tissue. Nuclear Medicine and Biology, 84-85, 63-72. doi: 10.1016/j.nucmedbio.2020.02.012 |
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2020 Journal Article Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructuresLeiske, Meike N., Walker, Julia A., Zia, Aadarash, Fletcher, Nicholas L., Thurecht, Kristofer J., Davis, Thomas P. and Kempe, Kristian (2020). Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures. Polymer Chemistry, 11 (16), 2799-2810. doi: 10.1039/d0py00304b |
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2020 Conference Publication Development and Biological Optimization of Star-Shaped Polymeric Nanoparticles for the Delivery of Therapeutic siRNA to Lung Cancer Cells In Vitro and In VivoMa, Zerong, Esser, Lars, Lai, May, Leiske, Meike N., Forgham, Helen, Wong, Sze W., Mansfeld, Friederike M., Lewis, Craig R., Davis, Thomas P., Quinn, John, Phillips, Phoebe, Kavallaris, Maria and McCarroll, Joshua A. (2020). Development and Biological Optimization of Star-Shaped Polymeric Nanoparticles for the Delivery of Therapeutic siRNA to Lung Cancer Cells In Vitro and In Vivo. 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy, Electr Network, 12-15 May 2020. Cambridge, MA, United States: Cell Press. |
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2020 Journal Article The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeabilityPeng, Scott, Grace, Megan S., Gondin, Arisbel B., Retamal, Jeffri S., Dill, Larissa, Darby, William, Bunnett, Nigel W., Abogadie, Fe C., Carbone, Simona E., Tigani, Tara, Davis, Thomas P., Poole, Daniel P., Veldhuis, Nicholas A. and McIntyre, Peter (2020). The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability. Laboratory Investigation, 100 (8), 1057-1067. doi: 10.1038/s41374-020-0430-7 |
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2020 Journal Article Recent advances in molecular imaging of atherosclerotic plaques and thrombosisQiao, Ruirui, Huang, Xumin, Qin, Yu, Li, Yuhuan, Davis, Thomas P., Hagemeyer, Christoph E. and Gao, Mingyuan (2020). Recent advances in molecular imaging of atherosclerotic plaques and thrombosis. Nanoscale, 12 (15), 8040-8064. doi: 10.1039/d0nr00599a |
