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2021 Journal Article Ex vivo culture of intact human patient derived pancreatic tumour tissueKokkinos, John, Sharbeen, George, Haghighi, Koroush S., Ignacio, Rosa Mistica C., Kopecky, Chantal, Gonzales-Aloy, Estrella, Youkhana, Janet, Timpson, Paul, Pereira, Brooke A., Ritchie, Shona, Pandzic, Elvis, Boyer, Cyrille, Davis, Thomas P., Butler, Lisa M., Goldstein, David, McCarroll, Joshua A. and Phillips, Phoebe A. (2021). Ex vivo culture of intact human patient derived pancreatic tumour tissue. Scientific Reports, 11 (1) 1944, 1944. doi: 10.1038/s41598-021-81299-0 |
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2021 Journal Article Engineering macromolecular nanocarriers for local delivery of gaseous signaling moleculesHu, Jinming, Fang, Yuanmeng, Huang, Xumin, Qiao, Ruirui, Quinn, John F. and Davis, Thomas P. (2021). Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules. Advanced Drug Delivery Reviews, 179 114005, 114005. doi: 10.1016/j.addr.2021.114005 |
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2021 Journal Article Dynamic protein corona of gold nanoparticles with an evolving morphologyNandakumar, Aparna, Wei, Wei, Siddiqui, Ghizal, Tang, Huayuan, Li, Yuhuan, Kakinen, Aleksandr, Wan, Xulin, Koppel, Kairi, Lin, Sijie, Davis, Thomas P., Leong, David T., Creek, Darren J., Ding, Feng, Song, Yang and Ke, Pu Chun (2021). Dynamic protein corona of gold nanoparticles with an evolving morphology. ACS Applied Materials and Interfaces, 13 (48), 58238-58251. doi: 10.1021/acsami.1c19824 |
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2021 Journal Article Intrinsic green fluorescent cross-linked poly(ester amide)s by spontaneous zwitterionic copolymerizationZia, Aadarash, Finnegan, John R., Morrow, Joshua P., Yin, Wenping, Jasieniak, Jacek J., Pentzer, Emily, Thickett, Stuart, Davis, Thomas P. and Kempe, Kristian (2021). Intrinsic green fluorescent cross-linked poly(ester amide)s by spontaneous zwitterionic copolymerization. Biomacromolecules, 22 (11), 4794-4804. doi: 10.1021/acs.biomac.1c01087 |
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2021 Journal Article Structure dependent differential modulation of Aβ fibrillization by selenadiazole-based inhibitorsKalsoom, Umme, Alazmi, Meshari, Farrukh, Hafiz Syed Usama Bin, Chung, Ka Hang Karen, Alshammari, Nawaf, Kakinen, Aleksandr, Chotana, Ghayoor Abbas, Javed, Ibrahim, Davis, Thomas Paul and Saleem, Rahman Shah Zaib (2021). Structure dependent differential modulation of Aβ fibrillization by selenadiazole-based inhibitors. ACS Chemical Neuroscience, 12 (20), 3806-3817. doi: 10.1021/acschemneuro.1c00478 |
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2021 Journal Article A framework of paracellular transport via nanoparticles‐induced endothelial leakinessLee, Myeongsang, Ni, Nengyi, Tang, Huayuan, Li, Yuhuan, Wei, Wei, Kakinen, Aleksandr, Wan, Xulin, Davis, Thomas P., Song, Yang, Leong, David Tai, Ding, Feng and Ke, Pu Chun (2021). A framework of paracellular transport via nanoparticles‐induced endothelial leakiness. Advanced Science, 8 (21) 2102519, e2102519. doi: 10.1002/advs.202102519 |
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2021 Journal Article Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cellsDao, Nam V., Ercole, Francesca, Li, Yuhuan, Davis, Thomas P., Kaminskas, Lisa M., Sloan, Erica K., Quinn, John F. and Whittaker, Michael R. (2021). Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells. Journal of Materials Chemistry B, 9 (37), 7805-7820. doi: 10.1039/d1tb00812a |
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2021 Journal Article Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticlesAndrikopoulos, Nicholas, Song, Zhiyuan, Wan, Xulin, Douek, Alon M., Javed, Ibrahim, Fu, Changkui, Xing, Yanting, Xin, Fangyun, Li, Yuhuan, Kakinen, Aleksandr, Koppel, Kairi, Qiao, Ruirui, Whittaker, Andrew K., Kaslin, Jan, Davis, Thomas P., Song, Yang, Ding, Feng and Ke, Pu Chun (2021). Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticles. Chemistry of Materials, 33 (16) acs.chemmater.1c01947, 6484-6500. doi: 10.1021/acs.chemmater.1c01947 |
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2021 Journal Article Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decadeBondarenko, Olesja, Mortimer, Monika, Kahru, Anne, Feliu, Neus, Javed, Ibrahim, Kakinen, Aleksandr, Lin, Sijie, Xia, Tian, Song, Yang, Davis, Thomas P., Lynch, Iseult, Parak, Wolfgang J., Leong, David Tai, Ke, Pu Chun, Chen, Chunying and Zhao, Yuliang (2021). Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade. Nano Today, 39 101184, 101184. doi: 10.1016/j.nantod.2021.101184 |
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2021 Journal Article Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibitionSharbeen, George, McCarroll, Joshua A., Akerman, Anouschka, Kopecky, Chantal, Youkhana, Janet, Kokkinos, John, Holst, Jeff, Boyer, Cyrille, Erkan, Mert, Goldstein, David, Timpson, Paul, Cox, Thomas R., Pereira, Brooke A., Chitty, Jessica L., Fey, Sigrid K., Najumudeen, Arafath K., Campbell, Andrew D., Sansom, Owen J., Ignacio, Rosa Mistica C., Naim, Stephanie, Liu, Jie, Russia, Nelson, Lee, Julia, Chou, Angela, Johns, Amber, Gill, Anthony J., Gonzales-Aloy, Estrella, Gebski, Val, Guan, Yi Fang ... Phillips, Phoebe A. (2021). Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition. Cancer Research, 81 (13), 3461-3479. doi: 10.1158/0008-5472.CAN-20-2496 |
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2021 Journal Article Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human bloodLeiske, Meike N., Lai, May, Amarasena, Thakshila, Davis, Thomas P., Thurecht, Kristofer J., Kent, Stephen J. and Kempe, Kristian (2021). Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood. Biomaterials, 274 120843, 120843. doi: 10.1016/j.biomaterials.2021.120843 |
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2021 Journal Article Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of miceRetamal, Jeffri S., Grace, Megan S., Dill, Larissa K., Ramirez-Garcia, Paulina, Peng, Scott, Gondin, Arisbel B., Bennetts, Felix, Alvi, Sadia, Rajasekhar, Pradeep, Almazi, Juhura G., Carbone, Simona E., Bunnett, Nigel W., Davis, Thomas P., Veldhuis, Nicholas A., Poole, Daniel P. and McIntyre, Peter (2021). Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice. Laboratory Investigation, 101 (7), 851-864. doi: 10.1038/s41374-021-00593-7 |
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2021 Journal Article Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidityLi, Yuhuan, Tang, Huayuan, Zhu, Houjuan, Kakinen, Aleksandr, Wang, Di, Andrikopoulos, Nicholas, Sun, Yunxiang, Nandakumar, Aparna, Kwak, Eunbi, Davis, Thomas P., Leong, David Tai, Ding, Feng and Ke, Pu Chun (2021). Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidity. ACS Applied Materials and Interfaces, 13 (25) acsami.1c06478, 29936-29948. doi: 10.1021/acsami.1c06478 |
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2021 Journal Article Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid betaSun, Yunxiang, Kakinen, Aleksandr, Wan, Xulin, Moriarty, Niamh, Hunt, Cameron P.J., Li, Yuhuan, Andrikopoulos, Nicholas, Nandakumar, Aparna, Davis, Thomas P., Parish, Clare L., Song, Yang, Ke, Pu Chun and Ding, Feng (2021). Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid beta. Nano Today, 38 101125, 101125. doi: 10.1016/j.nantod.2021.101125 |
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2021 Journal Article Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell ImmunityVu, Mai N., Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Esterbauer, Robyn, Davis, Thomas P., Truong, Nghia P., Wheatley, Adam K. and Kent, Stephen J. (2021). Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity. Advanced Healthcare Materials, 10 (10) 2002142, 1-12. doi: 10.1002/adhm.202002142 |
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2021 Journal Article Polymeric micelles with anti-virulence activity against Candida albicans in a single- and dual-species biofilmAlbayaty, Yassamin N., Thomas, Nicky, Ramirez-Garcia, Paulina D., Davis, Thomas P., Quinn, John F., Whittaker, Michael R. and Prestidge, Clive A. (2021). Polymeric micelles with anti-virulence activity against Candida albicans in a single- and dual-species biofilm. Drug Delivery and Translational Research, 11 (4), 1586-1597. doi: 10.1007/s13346-021-00943-4 |
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2021 Journal Article From influenza to COVID-19: lipid nanoparticle mRNA vaccines at the frontiers of infectious diseasesPilkington, Emily H., Suys, Estelle J.A., Trevaskis, Natalie L., Wheatley, Adam K., Zukancic, Danijela, Algarni, Azizah, Al-Wassiti, Hareth, Davis, Thomas P., Pouton, Colin W., Kent, Stephen J. and Truong, Nghia P. (2021). From influenza to COVID-19: lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases. Acta Biomaterialia, 131, 16-40. doi: 10.1016/j.actbio.2021.06.023 |
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2021 Journal Article In vitro and in vivo models for anti-amyloidosis nanomedicinesKakinen, Aleksandr, Javed, Ibrahim, Davis, Thomas P. and Ke, Pu Chun (2021). In vitro and in vivo models for anti-amyloidosis nanomedicines. Nanoscale Horizons, 6 (2), 95-119. doi: 10.1039/d0nh00548g |
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2021 Journal Article Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture modelDao, Nam V., Ercole, Francesca, Urquhart, Matthew C., Kaminskas, Lisa M., Nowell, Cameron J., Davis, Thomas P., Sloan, Erica K., Whittaker, Michael R. and Quinn, John F. (2021). Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model. Biomaterials Science, 9 (3), 835-846. doi: 10.1039/d0bm01544j |
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2021 Journal Article Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushesXu, Xin, Huang, Xumin, Chang, Yixin, Yu, Ye, Zhao, Jiacheng, Isahak, Naatasha, Teng, Jisi, Qiao, Ruirui, Peng, Hui, Zhao, Chun-Xia, Davis, Thomas P., Fu, Changkui and Whittaker, Andrew K. (2021). Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes. Biomacromolecules, 22 (2), 330-339. doi: 10.1021/acs.biomac.0c01193 |
