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2018 Conference Publication Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD miceBergot, A. S., Buckle,, Wright, C., Talekar, M., Hamilton-Williams, E. and Thomas, R. (2018). Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice. 15th International Symposium on Dendritic Cells (DC), Aachen, Germany, 10-14 June 2018. Hoboken, NJ, United States: Wiley. doi: 10.1002/eji.201871000 |
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2017 Journal Article CD11a/ICAM-1 blockade combined with IL-2 targeting therapy causes a paradoxical acceleration of type 1 diabetesBrenu, Ekua W., Bartley, Timothy J., Wright, Casey M. and Hamilton-Williams, Emma E. (2017). CD11a/ICAM-1 blockade combined with IL-2 targeting therapy causes a paradoxical acceleration of type 1 diabetes. Immunology and Cell Biology, 95 (9), 803-813. doi: 10.1038/icb.2017.49 |
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2017 Journal Article Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8+ T-cell priming to tolerance in autoimmune-prone NOD miceReeves, Peta L. S., Rudraraju, Rajeev, Wong, F. Susan, Hamilton-Williams, Emma E. and Steptoe, Raymond J. (2017). Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8+ T-cell priming to tolerance in autoimmune-prone NOD mice. European Journal of Immunology, 47 (9), 1550-1561. doi: 10.1002/eji.201747089 |
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2017 Journal Article APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD miceReeves, Peta L. S., Rudraraju, Rajeev, Liu, Xiao, Wong, F. Susan, Hamilton-Williams, Emma E. and Steptoe, Raymond J. (2017). APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice. Immunology and Cell Biology, 95 (9), 765-774. doi: 10.1038/icb.2017.48 |
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2017 Conference Publication Antigen specific immunotherapy for autoimmune disease targeting dendritic cellsBergot, Anne-Sophie, Talekar, Meghna, Nel, Hanno, Galea, Ryan, Harris, Mark, Hamilton-Williams, Emma and Thomas, Ranjeny (2017). Antigen specific immunotherapy for autoimmune disease targeting dendritic cells. 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS), Kanazawa Japan, 29 October - 2 November 2017. London United Kingdom: Elsevier. |
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2016 Journal Article Maintenance of peripheral tolerance to islet antigensHamilton-Williams, Emma E., Bergot, Anne-Sophie, Reeves, Peta L. S and Steptoe, Raymond J. (2016). Maintenance of peripheral tolerance to islet antigens. Journal of Autoimmunity, 72, 118-125. doi: 10.1016/j.jaut.2016.05.009 |
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2016 Journal Article Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic miceJames, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7 |
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2016 Conference Publication Type 1 diabetes susceptibility genes impair gut physiology and lead to perturbations in the microbiotaMullaney, J., Stephens, J. and Hamilton-Williams, E. (2016). Type 1 diabetes susceptibility genes impair gut physiology and lead to perturbations in the microbiota. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Development of a model for antigen-specific tolerising immunotherapy and response in NOD miceBuckle, I, Steptoe, R. J., Thomas, R. and Hamilton-Williams, E. E. (2016). Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2015 Journal Article Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetesPang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17 |
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2013 Journal Article Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexityHamilton-Williams, Emma E., Rainbow, Daniel B., Cheung, Jocelyn, Christensen, Mikkel, Lyons, Paul A., Peterson, Laurence B., Steward, Charles A., Sherman, Linda A. and Wicker, Linda S. (2013). Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity. Mammalian Genome, 24 (9-10), 358-375. doi: 10.1007/s00335-013-9466-y |
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2013 Journal Article Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetesLin, Xiaotian, Hamilton-Williams, Emma E., Rainbow, Daniel B., Hunter, Kara M., Dai, Yang D., Cheung, Jocelyn, Peterson, Laurence B., Wicker, Linda S. and Sherman, Linda A. (2013). Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes. Journal of Immunology, 190 (7), 3109-3120. doi: 10.4049/jimmunol.1203422 |
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2012 Journal Article PTPN22 alters the development of regulatory T cells in the thymusMaine, Christian J., Hamilton-Williams, Emma E., Cheung, Jocelyn, Stanford, Stephanie M., Bottini, Nunzio, Wicker, Linda S. and Sherman, Linda A. (2012). PTPN22 alters the development of regulatory T cells in the thymus. Journal of Immunology, 188 (11), 5267-5275. doi: 10.4049/jimmunol.1200150 |
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2012 Journal Article Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5Hamilton-Williams, Emma E., Cheung, Jocelyn, Rainbow, Daniel B., Hunter, Kara M., Wicker, Linda S. and Sherman, Linda A. (2012). Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5. Diabetes, 61 (1), 166-174. doi: 10.2337/db11-0790 |
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2011 Journal Article Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic miceSheng, Huiming, Hassanali, Saleena, Nugent, Courtney, Wen, Li, Hamilton-Williams, Emma, Dias, Peter and Dai, Yang D. (2011). Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. Journal of Immunology, 187 (4), 1591-1600. doi: 10.4049/jimmunol.1100231 |
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2011 Conference Publication Exosome-like microparticles can stimulate both innate and adaptive autoimmunity in non-obese diabetes miceDai, Yang, Sheng, Huiming, Hassanali, Saleema, Nugent, Courtney, Wen, Li, Hamilton-Williams, Emma and Dias, Peter (2011). Exosome-like microparticles can stimulate both innate and adaptive autoimmunity in non-obese diabetes mice. AMER ASSOC IMMUNOLOGISTS. |
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2010 Journal Article Idd9.2 and Idd9.3 Protective Alleles Function in CD4(+) T-Cells and Nonlymphoid Cells to Prevent Expansion of Pathogenic Islet-Specific CD8(+) T-CellsHamilton-Williams, Emma E., Wong, S.B. Justin, Martinez, Xavier, Rainbow, Daniel B., Hunter, Kara M., Wicker, Linda S. and Sherman, Linda A. (2010). Idd9.2 and Idd9.3 Protective Alleles Function in CD4(+) T-Cells and Nonlymphoid Cells to Prevent Expansion of Pathogenic Islet-Specific CD8(+) T-Cells. Diabetes, 59 (6), 1478-1486. doi: 10.2337/db09-1801 |
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2009 Journal Article Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic miceHamilton-Williams, Emma E., Martinez, Xavier, Clark, Jan, Howlett, Sarah, Hunter, Kara M., Rainbow, Daniel B., Wen, Li, Shlomchik, Mark J., Katz, Jonathan D., Beilhack, Georg F., Wicker, Linda S. and Sherman, Linda A. (2009). Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice. Journal of Immunology, 183 (3), 1533-1541. doi: 10.4049/jimmunol.0900428 |
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2009 Journal Article Correction to: Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injuryHeymann, Felix, Meyer-Schwesinger, Catherine, Hamilton-Williams, Emma E., Hammerich, Linda, Panzer, Ulf, Kaden, Sylvia, Quaggin, Susan E., Floege, Jurgen, Grone, Hermann-Josef and Kurts, Christian (2009). Correction to: Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury. Journal of Clinical Investigation, 119 (7), 2114-2114. doi: 10.1172/JCI38399C1 |
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2009 Journal Article Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injuryHeymann, Felix, Meyer-Schwesinger, Catherine, Hamilton-Williams, Emma E., Hammerich, Linda, Panzer, Ulf, Kaden, Sylvia, Quaggin, Susan E., Floege, Jurgen, Grone, Hermann-Josef and Kurts, Christian (2009). Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury. Journal of Clinical Investigation, 119 (5), 1286-1297. doi: 10.1172/JCI38399 |
