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2013

Journal Article

Structure and function of long noncoding RNAs in epigenetic regulation

Mercer, Tim R. and Mattick, John S. (2013). Structure and function of long noncoding RNAs in epigenetic regulation. Nature Structural & Molecular Biology, 20 (3), 300-307. doi: 10.1038/nsmb.2480

Structure and function of long noncoding RNAs in epigenetic regulation

2013

Journal Article

Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch

Marcellin, Esteban, Mercer, Tim R., Licona-Cassani, Cuauhtemoc, Palfreyman, Robin W., Dinger, Marcel E., Steen, Jennifer A., Mattick, John S. and Nielsen, Lars K. (2013). Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. BMC Genomics, 14 (1) 15, 15.1-15.9. doi: 10.1186/1471-2164-14-15

Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch

2013

Journal Article

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

Liu, Ganqiang, Mercer, Timothy R., Shearwood, Anne-Marie J., Siira, Stefan J., Hibbs, Moira E., Mattick, John S., Rackham, Oliver and Filipovska, Aleksandra (2013). Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting. Cell Reports, 5 (3), 839-848. doi: 10.1016/j.celrep.2013.09.036

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

2012

Journal Article

Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

Cruickshank, Mark N., Karimi, Mahdad, Mason, Rhonda L., Fenwick, Emily, Mercer, Tim, Tsao, Betty P., Boackle, Susan A. and Ulgiati, Daniela (2012). Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21). Molecular Immunology, 52 (3-4), 165-173. doi: 10.1016/j.molimm.2012.04.013

Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

2012

Journal Article

The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression

Rackham, Oliver, Mercer, Timothy R. and Filipovska, Aleksandra (2012). The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression. Wiley Interdisciplinary Reviews. RNA, 3 (5), 675-695. doi: 10.1002/wrna.1128

The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression

2012

Journal Article

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

Mercer, Tim R., Gerhardt, Daniel J., Dinger, Marcel E., Crawford, Joanna, Trapnell, Cole, Jeddeloh, Jeffrey A., Mattick, John S. and Rinn, John L. (2012). Targeted RNA sequencing reveals the deep complexity of the human transcriptome. Nature Biotechnology, 30 (1), 99-104. doi: 10.1038/nbt.2024

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

2011

Journal Article

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

Rackham, Oliver, Shearwood, Anne-Marie J., Mercer, Tim R., Davies, Stefan M. K., Mattick, John S. and Filipovska, Aleksandra (2011). Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins. RNA, 17 (12), 2085-2093. doi: 10.1261/rna.029405.111

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

2011

Journal Article

Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling

Thiagarajan, Rathi D., Cloonan, Nicole, Gardiner, Brooke B., Mercer, Tim R., Kolle, Gabriel, Nourbaksh, Ehsan, Wani, Shivangi, Tang, Dave, Krishnan, Keerthana, Georgas, Kylie M., Rumballe, Bree A., Chiu, Han S., Steen, Jason A., Mattick, John S., Little, Melissa H. and Grimmond, Sean M. (2011). Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling. BMC Genomics, 12 (1) 441, 441-1-441-16. doi: 10.1186/1471-2164-12-441

Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling

2011

Journal Article

RNA processing in human mitochondria

Lopez Sanchez, Maria I. G., Mercer, Tim R., Davies, Stefan M. K., Shearwood, Anne-Marie J., Nygard, Karoline K. A., Richman, Tara R., Mattick, John S., Rackham, Oliver and Filipovska, Aleksandra (2011). RNA processing in human mitochondria. Cell Cycle, 10 (17), 2904-2916. doi: 10.4161/cc.10.17.17060

RNA processing in human mitochondria

2011

Journal Article

The human mitochondrial transcriptome

Mercer, Tim R., Neph, Shane, Dinger, Marcel E., Crawford, Joanna, Smith, Martin A., Shearwood, Anne-Marie J., Haugen, Eric, Bracken, Cameron P., Rackham, Oliver, Stamatoyannopoulos, John A., Filipovska, Aleksandra and Mattick, John S. (2011). The human mitochondrial transcriptome. Cell, 146 (4), 645-658. doi: 10.1016/j.cell.2011.06.051

The human mitochondrial transcriptome

2011

Journal Article

Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage

Bracken, Cameron P., Szubert, Jan M., Mercer, Tim R., Dinger, Marcel E., Thomson, Daniel W., Mattick, John S., Michael, Michael Z. and Goodall, Gregory J. (2011). Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Research, 39 (13), 5658-5668. doi: 10.1093/nar/gkr110

Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage

2011

Journal Article

SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

Askarian-Amiri, Marjan E., Crawford, Joanna, French, Juliet D., Smart, Chanel E., Smith, Martin A., Clark, Michael B., Ru, Kelin, Mercer, Tim R., Thompson, Ella R., Lakhani, Sunil R., Vargas, Ana C., Campbell, Ian G., Brown, Melissa A., Dinger, Marcel E. and Mattick, John S. (2011). SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. RNA, 17 (5), 878-891. doi: 10.1261/rna.2528811

SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

2011

Journal Article

Expression of distinct RNAs from 3′ untranslated regions

Mercer, Tim R., Wilhelm, Dagmar, Dinger, Marcel E., Solda, Giulia, Korbie, Darren J., Glazov, Evgeny A., Truong, Vy, Schwenke, Maren, Simons, Cas, Matthaei, Klaus I., Saint, Robert, Koopman, Peter and Mattick, John S. (2011). Expression of distinct RNAs from 3′ untranslated regions. Nucleic Acids Research, 39 (6), 2393-2403. doi: 10.1093/nar/gkq1158

Expression of distinct RNAs from 3′ untranslated regions

2010

Journal Article

Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome

Mercer, Tim R., Dinger, Marcel E., Bracken, Cameron P., Kolle, Gabriel, Szubert, Jan M., Korbie, Darren J., Askarian-Amiri, Marjan E., Gardiner, Brooke B., Goodall, Gregory J., Grimmond, Sean M. and Mattick, John S. (2010). Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome. Genome Research, 20 (12), 1639-1650. doi: 10.1101/gr.112128.110

Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome

2010

Journal Article

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans

Taft, Ryan, Simons, Cas, Nahkuri, Satu, Oey, Harald, Korbie, Darren J., Mercer, Timothy R., Holst, Jeff, Ritchie, William, Wong, Justin J-L., Rasko, John E. J., Rokhsar, Daniel S., Degnan, Bernard M. and Mattick, John S. (2010). Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature Structural and Molecular Biology, 17 (8), 1030-1035. doi: 10.1038/nsmb.1841

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans

2010

Journal Article

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells

Lai, John, Lehman, Melanie L., Dinger, Marcel E., Hendy, Stephen C., Mercer, Tim R., Seim, Inge, Lawrence, Mitchell G., Mattick, John S., Clements, Judith A. and Nelson, Colleen C. (2010). A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells. RNA, 16 (6), 1156-1166. doi: 10.1261/rna.2019810

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells

2010

Journal Article

Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation

Mercer, Tim R., Qureshi, Irfan A., Gokhan, Solen, Dinger, Marcel E., Li, Guangyu, Mattick, John S. and Mehler, Mark F. (2010). Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation. BMC Neuroscience, 11 (1) 14, 1-15. doi: 10.1186/1471-2202-11-14

Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation

2009

Journal Article

Pervasive transcription of the eukaryotic genome: functional indices and conceptual implications

Dinger, M. E., Amaral, P. A., Mercer, T. R. and Mattick, J. S. (2009). Pervasive transcription of the eukaryotic genome: functional indices and conceptual implications. Briefings in Functional Genomics and Proteomics, 8 (6) elp038, 407-423. doi: 10.1093/bfgp/elp038

Pervasive transcription of the eukaryotic genome: functional indices and conceptual implications

2009

Journal Article

Non-coding RNAs: regulators of disease

Taft, R. J., Pang, K. C., Mercer, T. R., Dinger, M and Mattick, J. S. (2009). Non-coding RNAs: regulators of disease. Journal of Pathology, 220 (2), 126-139. doi: 10.1002/path.2638

Non-coding RNAs: regulators of disease

2009

Journal Article

Genome-wide identification of long noncoding RNAs in CD8(+) T cells

Pang, K. C., Dinger, M. E., Mercer, T. R., Malquori, L, Grimmond, S. M., Chen, W. S. and Mattick, J. S. (2009). Genome-wide identification of long noncoding RNAs in CD8(+) T cells. Journal of Immunology, 182 (12), 7738-7748. doi: 10.4049/jimmunol.0900603

Genome-wide identification of long noncoding RNAs in CD8(+) T cells