|
2008 Conference Publication Tumour depth influences vertical and horizontal expression of Cx26 in epidermis adjacent to malignant melanomaRipperger, D., Wladykowski, E., Haass, N. K., Fischer, F., Moll, I. and Brandner, J. M. (2008). Tumour depth influences vertical and horizontal expression of Cx26 in epidermis adjacent to malignant melanoma. 35th Annual Meeting of the Arbeitsgemeinschaft-Dermatolog-Forschung, Eriangen Germany, Feb 28-Mar 01, 2008. BLACKWELL PUBLISHING. |
|
2008 Journal Article Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activityTsai, James, Lee, John T., Wang, Weiru, Zhang, Jiazhong, Cho, Hanna, Mamo, Shumeye, Bremer, Ryan, Gillette, Sam, Kong, Jun, Haass, Nikolas K., Sproesser, Katrin, Li, Ling, Smalley, Keiran S. M., Fong, Daniel, Zhu, Yong-Liang, Marimuthu, Adhirai, Nguyen, Hoa, Lam, Billy, Liu, Jennifer, Cheung, Ivana, Rice, Julie, Suzuki, Yoshihisa, Luu, Catherine, Settachatgul, Calvin, Shellooe, Rafe, Cantwell, John, Kim, Sung-Hou, Schlessinger, Joseph, Zhang, Kam Y. J. ... Bollag, Gideon (2008). Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proceedings of the National Academy of Sciences of the United States of America, 105 (8), 3041-3046. doi: 10.1073/pnas.0711741105 |
|
2008 Journal Article In vitro three-dimensional tumor microenvironment models for anticancer drug discoverySmalley, Keiran S. M., Lioni, Mercedes, Noma, Kazuhiro, Haass, Nikolas K. and Herlyn, Meenhard (2008). In vitro three-dimensional tumor microenvironment models for anticancer drug discovery. Expert Opinion on Drug Discovery, 3 (1), 1-10. doi: 10.1517/17460441.3.1.1 |
|
2008 Journal Article Identification of American herring gull Larus smithsonianus and European herring gull L. argentatusGottschling, Martin, Haass, Nikolas K. and Buchheim, Andreas (2008). Identification of American herring gull Larus smithsonianus and European herring gull L. argentatus. Limicola, 22 (1), 1-29. |
|
2008 Book Chapter Targeting signaling pathways: in the search of melanoma's Achilles' heelHaass, Nikolas K., Hoeller, Christoph and Herlyn, Meenhard (2008). Targeting signaling pathways: in the search of melanoma's Achilles' heel. Regulation of Gene Expression in the Tumor Environment. (pp. 27-42) edited by Menashe Bar-Eli. London, UK: Springer. doi: 10.1007/978-1-4020-8341-9 |
|
2008 Journal Article The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxelHaass, Nikolas K., Sproesser, Katrin, Nguyen, Thiennga K., Contractor, Rooha, Medina, C. Angelica, Nathanson, Katherine L., Herlyn, Meenhard and Smalley, Keiran S. M. (2008). The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. Clinical Cancer Research, 14 (1), 230-239. doi: 10.1158/1078-0432.CCR-07-1440 |
|
2007 Conference Publication The novel MEK1/2 inhibitor AZD6244 (ARRY-142886) inhibits the growth of melanomas harboring the BRAF V600E mutation in vitro and in vivoHaass, N. K., Smalley, K. S., Sproesser, K., Contractor, R. and Herlyn, M. (2007). The novel MEK1/2 inhibitor AZD6244 (ARRY-142886) inhibits the growth of melanomas harboring the BRAF V600E mutation in vitro and in vivo. 68th Annual Meeting of the Society-for-Investigative-Dermatology, Los Angeles Ca, May 09-12, 2007. NATURE PUBLISHING GROUP. |
|
2007 Journal Article Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levelsSmalley, K. S. M., Contractor, R., Haass, N. K., Lee, J. T., Nathanson, K. L., Medina, C. A., Flaherty, K. T. and Herlyn, M. (2007). Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels. British Journal of Cancer, 96 (3), 445-449. doi: 10.1038/sj.bjc.6603596 |
|
2007 Journal Article An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cellsSmalley K.S.M., Contractor R., Haass N.K., Kulp A.N., Atilla-Gokcumen G.E., Williams D.S., Bregman H., Flaherty K.T., Soengas M.S., Meggers E. and Herlyn M. (2007). An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Research, 67 (1), 209-217. doi: 10.1158/0008-5472.CAN-06-1538 |
|
2007 Journal Article Expression of integrin alpha10 is induced in malignant melanomaWenke A.-K., Kjellman C., Lundgren-Akerlund E., Uhlmann C., Haass N.K., Herlyn M. and Bosserhoff A.K. (2007). Expression of integrin alpha10 is induced in malignant melanoma. Cellular Oncology, 29 (5), 373-386. |
|
2006 Journal Article Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastasesSmalley, Keiran S.M., Haass, Nikolas K., Brafford, Patricia A., Lioni, Mercedes, Flaherty, Keith T. and Herlyn, Meenhard (2006). Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Molecular Cancer Therapeutics, 5 (5), 1136-1144. doi: 10.1158/1535-7163.MCT-06-0084 |
|
2006 Conference Publication The microenvironment is the key determinant of melanoma drug resistanceHaass, N. K., Smalley, K. S. and Herlyn, M. (2006). The microenvironment is the key determinant of melanoma drug resistance. 67th Annual Meeting of the Society-for-Investigative-Dermatology, Philadelphia Pa, May 03-06, 2006. NATURE PUBLISHING GROUP. |
|
2006 Journal Article Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermisHaass N.K., Wladykowski E., Kief S., Moll I. and Brandner J.M. (2006). Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis. Journal of Histochemistry and Cytochemistry, 54 (2), 171-182. doi: 10.1369/jhc.5A6719.2005 |
|
2005 Journal Article Normal human melanocyte homeostasis as a paradigm for understanding melanomaHaass, NK and Herlyn, M (2005). Normal human melanocyte homeostasis as a paradigm for understanding melanoma. Journal of Investigative Dermatology Symposium Proceedings, 10 (2), 153-163. doi: 10.1111/j.1087-0024.2005.200407.x |
|
2005 Conference Publication Differential gap junctional intercellular communication between melanoma cells and cells in their microenvironmentHaass, N, Brandner, J, Brafford, P, Wladykowski, E, Kazianis, S, Moll, I and Herlyn, M (2005). Differential gap junctional intercellular communication between melanoma cells and cells in their microenvironment. 35th Annual Meeting of the European-Society-for-Dermatological-Research, Tubingen Germany, Sep 22-24, 2005. BLACKWELL PUBLISHING. |
|
2005 Journal Article Adhesion, migration and communication in melanocytes and melanomaHaass, Nikolas K., Smalley, Keiran S. M. , Li, Ling and Herlyn, Meenhard (2005). Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Research, 18 (3), 150-159. doi: 10.1111/j.1600-0749.2005.00235.x |
|
2005 Journal Article Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesionSmalley, KSM, Brafford, P, Haass, NK, Brandner, JM, Brown, E and Herlyn, M (2005). Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion. American Journal of Pathology, 166 (5), 1541-1554. doi: 10.1016/S0002-9440(10)62370-X |
|
2004 Conference Publication Connexins 26 and 43 are differentially induced in skin tumors and the adjacent epidermisHaass, NK, Wladykowski, E, Kief, S, Moll, I and Brandner, JM (2004). Connexins 26 and 43 are differentially induced in skin tumors and the adjacent epidermis. 34th Annual Meeting of the European-Society-for-Dermatological-Research, Vienna Austria, Sep 09-11, 2004. BLACKWELL PUBLISHING INC. |
|
2004 Journal Article The role of altered cell-cell communication in melanoma progressionHaass, Nikolas K., Smalley, Keiran S. M. and Herlyn, Meenhard (2004). The role of altered cell-cell communication in melanoma progression. Journal of Molecular Histology, 35 (3), 309-318. doi: 10.1023/B:HIJO.0000032362.35354.bb |
|
2004 Conference Publication Connexins are differentially expressed in melanoma and adjacent epidermisHaass, NK, Brandner, JM, Brafford, PA, Wladykowski, E, Kazianis, S, Smalley, KS, Moll, I and Herlyn, M (2004). Connexins are differentially expressed in melanoma and adjacent epidermis. 65th Annual Meeting of the Society-for-Investigative-Dermatology, Providence Ri, Apr 28-May 01, 2004. BLACKWELL PUBLISHING INC. |
