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2017

Journal Article

Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes. Angewandte Chemie International Edition, 56 (29). doi: 10.1002/anie.201782961

Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

2017

Journal Article

Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes. Angewandte Chemie, 129 (29), 8490-8494. doi: 10.1002/ange.201701596

Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

2017

Journal Article

Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes. Angewandte Chemie - International Edition, 56 (29), 8370-8374. doi: 10.1002/anie.201701596

Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes

2016

Journal Article

Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets

Ziegler, Melanie, Alt, Karen, Paterson, Brett M., Kanellakis, Peter, Bobik, Alex, Donnelly, Paul S., Hagemeyer, Christoph E. and Peter, Karlheinz (2016). Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets. Scientific Reports, 6 (1) 38161. doi: 10.1038/srep38161

Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets

2015

Journal Article

Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer

Gourni, Eleni, Del Pozzo, Luigi, Kheirallah, Emilie, Smerling, Christiane, Waser, Beatrice, Reubi, Jean-Claude, Paterson, Brett M., Donnelly, Paul S., Meyer, Philipp T. and Maecke, Helmut R. (2015). Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer. Molecular Pharmaceutics, 12 (8), 2781-2790. doi: 10.1021/mp500671j

Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer

2015

Journal Article

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

Alt, Karen, Paterson, Brett M., Westein, Erik, Rudd, Stacey E., Poniger, Stan S., Jagdale, Shweta, Ardipradja, Katie, Connell, Timothy U., Krippner, Guy Y., Nair, Ashish K. N., Wang, Xiaowei, Tochon-Danguy, Henri J., Donnelly, Paul S., Peter, Karlheinz and Hagemeyer, Christoph E. (2015). A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry. Angewandte Chemie - International Edition, 54 (26), 7515-7519. doi: 10.1002/anie.201411507

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

2015

Journal Article

The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution

Dearling, Jason L. J., Paterson, Brett M., Akurathi, Vamsidhar, Betanzos-Lara, Soledad, Treves, S. Ted, Voss, Stephan D., White, Jonathan M., Huston, James S., Smith, Suzanne V., Donnelly, Paul S. and Packard, Alan B. (2015). The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution. Bioconjugate Chemistry, 26 (4), 707-717. doi: 10.1021/acs.bioconjchem.5b00049

The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution

2015

Journal Article

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B

Ma, Michelle T., Meszaros, Levente K., Paterson, Brett M., Berry, David J., Cooper, Maggie S., Ma, Yongmin, Hider, Robert C. and Blower, Philip J. (2015). Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B. Dalton Transactions, 44 (11), 4884-4900. doi: 10.1039/c4dt02978j

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B

2015

Journal Article

Engineering poly(ethylene glycol) particles for improved biodistribution

Cui, Jiwei, De Rose, Robert, Alt, Karen, Alcantara, Sheilajen, Paterson, Brett M., Liang, Kang, Hu, Ming, Richardson, Joseph J., Yan, Yan, Jeffery, Charmaine M., Price, Roger I., Peter, Karlheinz, Hagemeyer, Christoph E., Donnelly, Paul S., Kent, Stephen J. and Caruso, Frank (2015). Engineering poly(ethylene glycol) particles for improved biodistribution. ACS Nano, 9 (2), 1571-1580. doi: 10.1021/nn5061578

Engineering poly(ethylene glycol) particles for improved biodistribution

2015

Journal Article

Bifunctional 64Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography

Paterson, Brett M., Buncic, Gojko, McInnes, Lachlan E., Roselt, Peter, Cullinane, Carleen, Binns, David S., Jeffery, Charmaine M., Price, Roger I., Hicks, Rodney J. and Donnelly, Paul S. (2015). Bifunctional 64Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography. Dalton Transactions, 44 (11), 4901-4909. doi: 10.1039/c4dt02983f

Bifunctional 64Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography

2014

Journal Article

+ complexes of exo-functionalized tridentate "click" macrocycles: Synthesis, stability, photophysical properties, bioconjugation, and antibacterial activity

Noor, Asif, Huff, Gregory S., Kumar, Sreedhar V., Lewis, James E. M., Paterson, Brett M., Schieber, Christine, Donnelly, Paul S., Brooks, Heather J. L., Gordon, Keith C., Moratti, Stephen C. and Crowley, James D. (2014). + complexes of exo-functionalized tridentate "click" macrocycles: Synthesis, stability, photophysical properties, bioconjugation, and antibacterial activity. Organometallics, 33 (24), 7031-7043. doi: 10.1021/om500664v

+ complexes of exo-functionalized tridentate "click" macrocycles: Synthesis, stability, photophysical properties, bioconjugation, and antibacterial activity

2014

Journal Article

Single-Chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets

Alt, Karen, Paterson, Brett M., Ardipradja, Katie, Schieber, Christine, Buncic, Gojko, Lim, Bock, Poniger, Stan S., Jakoby, Bjoern, Wang, Xiaowei, Okeefe, Graeme J., Tochon-Danguy, Henri J., Scott, Andrew M., Ackermann, Uwe, Peter, Karlheinz, Donnelly, Paul S. and Hagemeyer, Christoph E. (2014). Single-Chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets. Molecular Pharmaceutics, 11 (8), 2855-2863. doi: 10.1021/mp500209a

Single-Chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets

2014

Journal Article

Enzyme-mediated site-specific bioconjugation of metal complexes to proteins: Sortase-mediated coupling of copper-64 to a single-chain antibody

Paterson, Brett M., Alt, Karen, Jeffery, Charmaine M., Price, Roger I., Jagdale, Shweta, Rigby, Sheena, Williams, Charlotte C., Peter, Karlheinz, Hagemeyer, Christoph E. and Donnelly, Paul S. (2014). Enzyme-mediated site-specific bioconjugation of metal complexes to proteins: Sortase-mediated coupling of copper-64 to a single-chain antibody. Angewandte Chemie - International Edition, 53 (24), 6115-6119. doi: 10.1002/anie.201402613

Enzyme-mediated site-specific bioconjugation of metal complexes to proteins: Sortase-mediated coupling of copper-64 to a single-chain antibody

2014

Journal Article

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

Bica, Laura, Liddell, Jeffrey R., Donnelly, Paul S., Duncan, Clare, Caragounis, Aphrodite, Volitakis, Irene, Paterson, Brett M., Cappai, Roberto, Grubman, Alexandra, Camakaris, James, Crouch, Peter J. and White, Anthony R. (2014). Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation. PLoS ONE, 9 (2) e90070, e90070. doi: 10.1371/journal.pone.0090070

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

2014

Journal Article

PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate

Paterson, Brett M., Roselt, Peter, Denoyer, Delphine, Cullinane, Carleen, Binns, David, Noonan, Wayne, Jeffery, Charmaine M., Price, Roger I., White, Jonathan M., Hicks, Rodney J. and Donnelly, Paul S. (2014). PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate. Dalton Transactions, 43 (3), 1386-1396. doi: 10.1039/c3dt52647j

PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate

2014

Journal Article

Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

Djoko, Karrera Y., Paterson, Brett M., Donnelly, Paul S. and McEwan, Alastair G. (2014). Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action. Metallomics, Advance Article (4), 1-10. doi: 10.1039/C3MT00348E

Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

2014

Journal Article

Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

Roberts, Blaine R., Lim, Nastasia K. H., McAllum, Erin J., Donnelly, Paul S., Hare, Dominic J., Doble, Philip A., Turner, Bradley J., Price, Katherine A., Lim, Sin Chun, Paterson, Brett M., Hickey, James L., Rhoads, Timothy W., Williams, Jared R., Kanninen, Katja M., Hung, Lin W., Liddell, Jeffrey R., Grubman, Alexandra, Monty, Jean-Francois, Llanos, Roxana M., Kramer, David R., Mercer, Julian F. B., Bush, Ashley I., Masters, Colin L., Duce, James A., Li, Qiao-Xin, Beckman, Joseph S., Barnham, Kevin J., White, Anthony R. and Crouch, Peter J. (2014). Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroscience, 34 (23), 8021-8031. doi: 10.1523/JNEUROSCI.4196-13.2014

Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

2013

Journal Article

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

McAllum, Erin J., Lim, Nastasia K.-H., Hickey, James L., Paterson, Brett M., Donnelly, Paul S., Li, Qiao-Xin, Liddell, Jeffrey R., Barnham, Kevin J., White, Anthony R. and Crouch, Peter J. (2013). Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (7-8), 586-590. doi: 10.3109/21678421.2013.824000

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

2013

Journal Article

Diagnostic imaging agents for alzheimer's disease: Copper radiopharmaceuticals that target aβ plaques

Hickey, James L., Lim, Sinchun, Hayne, David J., Paterson, Brett M., White, Jonathan M., Villemagne, Victor L., Roselt, Peter, Binns, David, Cullinane, Carleen, Jeffery, Charmaine M., Price, Roger I., Barnham, Kevin J. and Donnelly, Paul S. (2013). Diagnostic imaging agents for alzheimer's disease: Copper radiopharmaceuticals that target aβ plaques. Journal of the American Chemical Society, 135 (43), 16120-16132. doi: 10.1021/ja4057807

Diagnostic imaging agents for alzheimer's disease: Copper radiopharmaceuticals that target aβ plaques

2013

Journal Article

Increasing intracellular bioavailable copper selectively targets prostate cancer cells

Cater, Michael A., Pearson, Helen B., Wolyniec, Kamil, Klaver, Paul, Bilandzic, Maree, Paterson, Brett M., Bush, Ashley I., Humbert, Patrick O., La Fontaine, Sharon, Donnelly, Paul S. and Haupt, Ygal (2013). Increasing intracellular bioavailable copper selectively targets prostate cancer cells. ACS Chemical Biology, 8 (7), 1621-1631. doi: 10.1021/cb400198p

Increasing intracellular bioavailable copper selectively targets prostate cancer cells