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2013

Journal Article

Copper modulates the large dense core vesicle secretory pathway in PC12 cells

Duncan, Clare, Bica, Laura, Crouch, Peter J., Caragounis, Aphrodite, Lidgerwood, Grace E., Parker, Sarah J., Meyerowitz, Jodi, Volitakis, Irene, Liddell, Jeffrey R., Raghupathi, Ravinarayan, Paterson, Brett M., Duffield, Michael D., Cappai, Roberto, Donnelly, Paul S., Grubman, Alexandra, Camakaris, James, Keating, Damien J. and White, Anthony R. (2013). Copper modulates the large dense core vesicle secretory pathway in PC12 cells. Metallomics, 5 (6), 700-714. doi: 10.1039/c3mt20231c

Copper modulates the large dense core vesicle secretory pathway in PC12 cells

2013

Journal Article

Increased Zinc and Manganese in Parallel with Neurodegeneration, Synaptic Protein Changes and Activation of Akt/GSK3 Signaling in Ovine CLN6 Neuronal Ceroid Lipofuscinosis

Kanninen, Katja M., Grubman, Alexandra, Meyerowitz, Jodi, Duncan, Clare, Tan, Jiang-Li, Parker, Sarah J., Crouch, Peter J., Paterson, Brett M., Hickey, James L., Donnelly, Paul S., Volitakis, Irene, Tammen, Imke, Palmer, David N. and White, Anthony R. (2013). Increased Zinc and Manganese in Parallel with Neurodegeneration, Synaptic Protein Changes and Activation of Akt/GSK3 Signaling in Ovine CLN6 Neuronal Ceroid Lipofuscinosis. PLoS ONE, 8 (3) e58644, e58644. doi: 10.1371/journal.pone.0058644

Increased Zinc and Manganese in Parallel with Neurodegeneration, Synaptic Protein Changes and Activation of Akt/GSK3 Signaling in Ovine CLN6 Neuronal Ceroid Lipofuscinosis

2012

Journal Article

Inhibition of TDP-43 accumulation by Bis(thiosemicarbazonato)-copper complexes

Parker, Sarah J., Meyerowitz, Jodi, James, Janine L., Liddell, Jeffrey R., Nonaka, Takashi, Hasegawa, Masato, Kanninen, Katja M., Lim, SinChun, Paterson, Brett M., Donnelly, Paul S., Crouch, Peter J. and White, Anthony R. (2012). Inhibition of TDP-43 accumulation by Bis(thiosemicarbazonato)-copper complexes. PLoS ONE, 7 (8) e42277. doi: 10.1371/journal.pone.0042277

Inhibition of TDP-43 accumulation by Bis(thiosemicarbazonato)-copper complexes

2012

Journal Article

An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copper II

Donnelly, Paul S., Liddell, Jeffrey R., Lim, SinChun, Paterson, Brett M., Cater, Michael A., Savva, Maria S., Mot, Alexandra I., James, Janine L., Trounce, Ian A., White, Anthony R. and Crouch, Peter J. (2012). An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copper II . Proceedings of the National Academy of Sciences of the United States of America, 109 (1), 47-52. doi: 10.1073/pnas.1116227108

An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copper II

2011

Journal Article

Subcellular localization of a fluorescent derivative of Cu II(atsm) offers insight into the neuroprotective action of Cu II(atsm)

Price, Katherine Ann, Crouch, Peter J., Lim, Sinchun, Paterson, Brett M., Liddell, Jeffrey R., Donnelly, Paul S. and White, Anthony R. (2011). Subcellular localization of a fluorescent derivative of Cu II(atsm) offers insight into the neuroprotective action of Cu II(atsm). Metallomics, 3 (12), 1280-1290. doi: 10.1039/c1mt00092f

Subcellular localization of a fluorescent derivative of Cu II(atsm) offers insight into the neuroprotective action of Cu II(atsm)

2011

Journal Article

Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes

Price, Katherine Ann, Crouch, Peter J., Volitakis, Irene, Paterson, Brett M., Lim, Sinchun, Donnelly, Paul S. and White, Anthony R. (2011). Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes. Inorganic Chemistry, 50 (19), 9594-9605. doi: 10.1021/ic201334q

Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes

2011

Journal Article

Copper complexes of bis(thiosemicarbazones): From chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals

Paterson, Brett M. and Donnelly, Paul S. (2011). Copper complexes of bis(thiosemicarbazones): From chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals. Chemical Society Reviews, 40 (5), 3005-3018. doi: 10.1039/c0cs00215a

Copper complexes of bis(thiosemicarbazones): From chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals

2011

Journal Article

Cell cycle arrest in cultured neuroblastoma cells exposed to a bis(thiosemicarbazonato) metal complex

Bica, Laura, Meyerowitz, Jodi, Parker, Sarah J., Caragounis, Aphrodite, Du, Tai, Paterson, Brett M., Barnham, Kevin J., Crouch, Peter J., White, Anthony R. and Donnelly, Paul S. (2011). Cell cycle arrest in cultured neuroblastoma cells exposed to a bis(thiosemicarbazonato) metal complex. BioMetals, 24 (1), 117-133. doi: 10.1007/s10534-010-9380-7

Cell cycle arrest in cultured neuroblastoma cells exposed to a bis(thiosemicarbazonato) metal complex

2010

Journal Article

A copper radiopharmaceutical for diagnostic imaging of Alzheimer's disease: A bis(thiosemicarbazonato)copper(ii) complex that binds to amyloid-β plaques

Lim, Sinchun, Paterson, Brett M., Fodero-Tavoletti, Michelle T., O'Keefe, Graeme J., Cappai, Roberto, Barnham, Kevin J., Villemagne, Victor L. and Donnelly, Paul S. (2010). A copper radiopharmaceutical for diagnostic imaging of Alzheimer's disease: A bis(thiosemicarbazonato)copper(ii) complex that binds to amyloid-β plaques. Chemical Communications, 46 (30), 5437-5439. doi: 10.1039/c0cc01175d

A copper radiopharmaceutical for diagnostic imaging of Alzheimer's disease: A bis(thiosemicarbazonato)copper(ii) complex that binds to amyloid-β plaques

2010

Journal Article

A water-soluble bis(thiosemicarbazone) ligand. A sensitive probe and metal buffer for zinc

Buncic, Gojko, Donnelly, Paul S., Paterson, Brett M., White, Jonathan M., Zimmermann, Matthias, Xiao, Zhiguang and Wedd, Anthony G. (2010). A water-soluble bis(thiosemicarbazone) ligand. A sensitive probe and metal buffer for zinc. Inorganic Chemistry, 49 (7), 3071-3073. doi: 10.1021/ic902370a

A water-soluble bis(thiosemicarbazone) ligand. A sensitive probe and metal buffer for zinc

2010

Journal Article

A hexadentate bis(thiosemicarbazonato) ligand: Rhenium(v), iron(iii) and cobalt(iii) complexes

Paterson, Brett M., White, Jonathan M. and Donnelly, Paul S. (2010). A hexadentate bis(thiosemicarbazonato) ligand: Rhenium(v), iron(iii) and cobalt(iii) complexes. Dalton Transactions, 39 (11), 2831-2837. doi: 10.1039/b922127a

A hexadentate bis(thiosemicarbazonato) ligand: Rhenium(v), iron(iii) and cobalt(iii) complexes

2010

Journal Article

Versatile new bis(thiosemicarbazone) bifunctional chelators: Synthesis, conjugation to bombesin(7-14)-NH2, and copper-64 radiolabeling

Brett M. Paterson, M. Paterson, John A. Karas, A. Karas, Denis B. Scanlon, B. Scanlon, Jonathan M. White, M. White and Donnelly, Paul S. (2010). Versatile new bis(thiosemicarbazone) bifunctional chelators: Synthesis, conjugation to bombesin(7-14)-NH2, and copper-64 radiolabeling. Inorganic Chemistry, 49 (4), 1884-1893. doi: 10.1021/ic902204e

Versatile new bis(thiosemicarbazone) bifunctional chelators: Synthesis, conjugation to bombesin(7-14)-NH2, and copper-64 radiolabeling

2010

Journal Article

Copper and zinc bis(thiosemicarbazonato) complexes with a fluorescent tag: Synthesis, radiolabelling with copper-64, cell uptake and fluorescence studies

Lim, Sinchun, Price, Katherine A., Chong, Siow-Feng, Paterson, Brett M., Caragounis, Aphrodite, Barnham, Kevin J., Crouch, Peter J., Peach, Josephine M., Dilworth, Jonathan R., White, Anthony R. and Donnelly, Paul S. (2010). Copper and zinc bis(thiosemicarbazonato) complexes with a fluorescent tag: Synthesis, radiolabelling with copper-64, cell uptake and fluorescence studies. Journal of Biological Inorganic Chemistry, 15 (2), 225-235. doi: 10.1007/s00775-009-0587-4

Copper and zinc bis(thiosemicarbazonato) complexes with a fluorescent tag: Synthesis, radiolabelling with copper-64, cell uptake and fluorescence studies

2010

Journal Article

Bis (thiosemicarbazonato) Cu-64 complexes for positron emission tomography imaging of Alzheimer's disease

Fodero-Tavoletti, Michelle T., Villemagne, Victor L., Paterson, Brett M., White, Anthony R., Li, Qiao-Xin, Camakaris, James, O'keefe, Graeme, Cappai, Roberto, Barnham, Kevin J. and Donnelly, Paul S. (2010). Bis (thiosemicarbazonato) Cu-64 complexes for positron emission tomography imaging of Alzheimer's disease. Journal of Alzheimer's Disease, 20 (1), 49-55. doi: 10.3233/JAD-2010-1359

Bis (thiosemicarbazonato) Cu-64 complexes for positron emission tomography imaging of Alzheimer's disease

2009

Journal Article

Sustained activation of glial cell epidermal growth factor receptor by bis(thiosemicarbazonato) metal complexes is associated with inhibition of protein tyrosine phosphatase activity

Price, Katherine Ann, Caragounis, Aphrodite, Paterson, Brett M., Filiz, Gulay, Volitakis, Irene, Masters, Colin L., Barnham, Kevin J., Donnelly, Paul S., Crouch, Peter J. and White, Anthony R. (2009). Sustained activation of glial cell epidermal growth factor receptor by bis(thiosemicarbazonato) metal complexes is associated with inhibition of protein tyrosine phosphatase activity. Journal of Medicinal Chemistry, 52 (21), 6606-6620. doi: 10.1021/jm9007938

Sustained activation of glial cell epidermal growth factor receptor by bis(thiosemicarbazonato) metal complexes is associated with inhibition of protein tyrosine phosphatase activity

2007

Journal Article

New bimetallic compounds based on the bis(thiosemicarbazonato) motif

Christlieb, Martin, Cowley, Andrew R., Dilworth, Jonathan R., Donnelly, Paul S., Paterson, Brett M., Struthers, Harriet S. R. and White, Jonathan M. (2007). New bimetallic compounds based on the bis(thiosemicarbazonato) motif. Dalton Transactions (3), 327-331. doi: 10.1039/b612907b

New bimetallic compounds based on the bis(thiosemicarbazonato) motif