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2020

Journal Article

Treading lightly in a pandemic: #Zentensivist reflections on COVID-19

Siuba, Matthew T., Dugar, Siddharth and Shekar, Kiran (2020). Treading lightly in a pandemic: #Zentensivist reflections on COVID-19. Chest, 158 (2), 471-473. doi: 10.1016/j.chest.2020.04.013

Treading lightly in a pandemic: #Zentensivist reflections on COVID-19

2020

Journal Article

Position paper on global extracorporeal membrane oxygenation education and educational agenda for the future: a statement from the Extracorporeal Life Support Organization ECMOed Taskforce

Zakhary, Bishoy, Shekar, Kiran, Diaz, Rodrigo, Badulak, Jenelle, Johnston, Lindsay, Roeleveld, Peter Paul, Alinier, Guillaume, Lai, Peter Chi Keung, Ramanathan, Kollengode, Moore, Elizabeth, Hassan, Ibrahim, Agerstrand, Cara, Ngai, Wallace Chun-Wai, Salazar, Leonardo, Raman, Lakshmi, Bembea, Melania M., Davidson, Mark, Gomez-Gutierrez, Rene D., Mateo-Sidrón, Jose Alfonso Rubio, Kukutschka, Jeannie, Antonini, Marta V., Dickstein, Marc L., Schmidt, Matthieu, Abrams, Darryl and Ogino, Mark T. (2020). Position paper on global extracorporeal membrane oxygenation education and educational agenda for the future: a statement from the Extracorporeal Life Support Organization ECMOed Taskforce. Critical Care Medicine, 48 (3), 406-414. doi: 10.1097/CCM.0000000000004158

Position paper on global extracorporeal membrane oxygenation education and educational agenda for the future: a statement from the Extracorporeal Life Support Organization ECMOed Taskforce

2020

Journal Article

Mechanical ventilation for acute respiratory distress syndrome during extracorporeal life support research and practice

Abrams, Darryl, Schmidt, Matthieu, Pham, Tái, Beitler, Jeremy R., Fan, Eddy, Goligher, Ewan C., McNamee, James J., Patroniti, Nicoló, Wilcox, M. Elizabeth, Combes, Alain, Ferguson, Niall D., McAuley, Danny F., Pesenti, Antonio, Quintel, Michael, Fraser, John, Hodgson, Carol L., Hough, Catherine L., Mercat, Alain, Mueller, Thomas, Pellegrino, Vin, Ranieri, V. Marco, Rowan, Kathy, Shekar, Kiran, Brochard, Laurent and Brodie, Daniel (2020). Mechanical ventilation for acute respiratory distress syndrome during extracorporeal life support research and practice. American Journal of Respiratory and Critical Care Medicine, 201 (5), 514-525. doi: 10.1164/rccm.201907-1283CI

Mechanical ventilation for acute respiratory distress syndrome during extracorporeal life support research and practice

2020

Journal Article

Assessment of the Clinical Pulmonary Infection Scores for prediction of ventilator associated pneumonia in patients with out of hospital cardiac arrest

Manchal, Naveen, Siriwardena, Maithri, Hay, Karen, Shekar, Kiran and McNamara, John F. (2020). Assessment of the Clinical Pulmonary Infection Scores for prediction of ventilator associated pneumonia in patients with out of hospital cardiac arrest. Infection, Disease and Health, 26 (1), 48-54. doi: 10.1016/j.idh.2020.09.001

Assessment of the Clinical Pulmonary Infection Scores for prediction of ventilator associated pneumonia in patients with out of hospital cardiac arrest

2020

Journal Article

Clinical care of pregnant and postpartum women with COVID-19: living recommendations from the National COVID-19 Clinical Evidence Taskforce

Vogel, Joshua P., Tendal, Britta, Giles, Michelle, Whitehead, Clare, Burton, Wendy, Chakraborty, Samantha, Cheyne, Saskia, Downton, Teena, Fraile Navarro, David, Gleeson, Glenda, Gordon, Adrienne, Hunt, Jenny, Kitschke, Jackie, McDonald, Steven, McDonnell, Nolan, Middleton, Philippa, Millard, Tanya, Murano, Melissa, Oats, Jeremy, Tate, Rhiannon, White, Heath, Elliott, Julian, Roach, Vijay, Homer, Caroline S.E., McGowan, Sharon, Ballenden, Nicola, Barrett, Terri-Lee, Beavis, Vanessa, Saunders, James Beckford ... Mintzes, Barbara (2020). Clinical care of pregnant and postpartum women with COVID-19: living recommendations from the National COVID-19 Clinical Evidence Taskforce. Australian and New Zealand Journal of Obstetrics and Gynaecology, 60 (6) ajo.13270, 840-851. doi: 10.1111/ajo.13270

Clinical care of pregnant and postpartum women with COVID-19: living recommendations from the National COVID-19 Clinical Evidence Taskforce

2019

Journal Article

Risk factors for mortality in patients undergoing cardiothoracic surgery for infective endocarditis

Kumar, Aashish, Anstey, Chris, Tesar, Peter and Shekar, Kiran (2019). Risk factors for mortality in patients undergoing cardiothoracic surgery for infective endocarditis. Annals of Thoracic Surgery, 108 (4), 1101-1106. doi: 10.1016/j.athoracsur.2019.05.029

Risk factors for mortality in patients undergoing cardiothoracic surgery for infective endocarditis

2019

Journal Article

Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?

Abdul-Aziz, Mohd H., Shekar, Kiran and Roberts, Jason A. (2019). Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?. Anaesthesia Critical Care and Pain Medicine, 38 (5), 451-453. doi: 10.1016/j.accpm.2019.07.005

Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?

2019

Journal Article

Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? No

Shekar, Kiran and Brodie, Daniel (2019). Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? No. Critical Care Medicine, 47 (8), 1147-1149. doi: 10.1097/CCM.0000000000003865

Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? No

2019

Journal Article

ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sand

Schmidt, Matthieu, Combes, Alain and Shekar, Kiran (2019). ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sand. Intensive Care Medicine, 45 (8), 1140-1142. doi: 10.1007/s00134-019-05632-y

ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sand

2019

Journal Article

Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndrome

Shekar, Kiran and Schmidt, Matthieu (2019). Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine, 200 (2), 265-266. doi: 10.1164/rccm.201903-0594LE

Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndrome

2019

Journal Article

Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?

Shekar, Kiran, Abrams, Darryl and Schmidt, Matthieu (2019). Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?. Journal of Thoracic Disease, 11 (7), 2656-2659. doi: 10.21037/jtd.2019.05.58

Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?

2019

Journal Article

Steps to enhance safety of tracheostomy on ECMO

Grewal, Jatinder, Sutt, Anna-Liisa, Shekar, Kiran and Fraser, John F. (2019). Steps to enhance safety of tracheostomy on ECMO. Journal of Intensive Care Medicine, 2019, 088506661985107-2. doi: 10.1177/0885066619851074

Steps to enhance safety of tracheostomy on ECMO

2019

Journal Article

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy

Adiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Tesar, Peter, Naidoo, Rishendran, Rapchuk, Ivan, Belz, Stephen, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2019). Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy. Methods and Protocols, 2 (2) 38, 38-12. doi: 10.3390/mps2020038

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy

2019

Journal Article

Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation

Shekar, Kiran, Grewal, Jatinder, Sutt, Anna Lisa and Fraser, John (2019). Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation. ASAIO journal (American Society for Artificial Internal Organs : 1992), 65 (4), e44-e45. doi: 10.1097/MAT.0000000000000969

Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation

2019

Journal Article

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

Passmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

2019

Journal Article

Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience

Grewal, Jatinder, Sutt, Anna-Liisa, Cornmell, George, Shekar, Kiran and Fraser, John (2019). Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience. Journal of Intensive Care Medicine, 35 (11), 1153-1161. doi: 10.1177/0885066619837939

Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience

2019

Journal Article

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients

Cheng, Vesa, Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2019). Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients. Expert Opinion on Drug Metabolism & Toxicology, 15 (2), 103-112. doi: 10.1080/17425255.2019.1563596

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients

2019

Journal Article

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

2018

Journal Article

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

2018

Journal Article

Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future

Boyle, Andrew J., Sklar, Michael C., McNamee, James J., Brodie, Daniel, Slutsky, Arthur S., Brochard, Laurent, McAuley, Daniel F., International ECMO Network (ECMONet) and Shekar, Kiran (2018). Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future. The Lancet. Respiratory medicine, 6 (11), 874-884. doi: 10.1016/S2213-2600(18)30326-6

Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future